HRP20150578T1 - Metoda za stabilizaciju s-nitrozoglutationa i sastav pripremljen tom metodom - Google Patents
Metoda za stabilizaciju s-nitrozoglutationa i sastav pripremljen tom metodom Download PDFInfo
- Publication number
- HRP20150578T1 HRP20150578T1 HRP20150578TT HRP20150578T HRP20150578T1 HR P20150578 T1 HRP20150578 T1 HR P20150578T1 HR P20150578T T HRP20150578T T HR P20150578TT HR P20150578 T HRP20150578 T HR P20150578T HR P20150578 T1 HRP20150578 T1 HR P20150578T1
- Authority
- HR
- Croatia
- Prior art keywords
- nitrosoglutathione
- stabilization
- same
- composition prepared
- pharmaceutical composition
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title claims 4
- HYHSBSXUHZOYLX-WDSKDSINSA-N S-nitrosoglutathione Chemical compound OC(=O)[C@@H](N)CCC(=O)N[C@@H](CSN=O)C(=O)NCC(O)=O HYHSBSXUHZOYLX-WDSKDSINSA-N 0.000 title claims 2
- 108010001742 S-Nitrosoglutathione Proteins 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 230000006641 stabilisation Effects 0.000 title 1
- 238000011105 stabilization Methods 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 3
- 229920000642 polymer Polymers 0.000 claims 3
- 229920001282 polysaccharide Polymers 0.000 claims 2
- 239000005017 polysaccharide Substances 0.000 claims 2
- 150000004804 polysaccharides Chemical class 0.000 claims 2
- 239000004480 active ingredient Substances 0.000 claims 1
- 239000000654 additive Substances 0.000 claims 1
- 229920000615 alginic acid Polymers 0.000 claims 1
- 229960001126 alginic acid Drugs 0.000 claims 1
- 235000010443 alginic acid Nutrition 0.000 claims 1
- 239000000783 alginic acid Substances 0.000 claims 1
- 150000004781 alginic acids Chemical class 0.000 claims 1
- 238000001035 drying Methods 0.000 claims 1
- 238000004108 freeze drying Methods 0.000 claims 1
- 229920001223 polyethylene glycol Polymers 0.000 claims 1
- 229920002451 polyvinyl alcohol Polymers 0.000 claims 1
- 229920000036 polyvinylpyrrolidone Polymers 0.000 claims 1
- 150000003839 salts Chemical class 0.000 claims 1
- 239000007787 solid Substances 0.000 claims 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Neurology (AREA)
- Diabetes (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Pulmonology (AREA)
- Endocrinology (AREA)
- Cardiology (AREA)
- Emergency Medicine (AREA)
- Hematology (AREA)
- Heart & Thoracic Surgery (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Obesity (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Claims (3)
1. Farmaceutski sastav obuhvaća GSNO kao aktivni sastojak zajedno s uobičajenim aditivima i jedan ili više farmaceutski prihvatljivih polimera odabranih iz grupe polisaharida, PVA, PVP, PEG, alginske kiseline i njenih soli, gdje je pH vrijednost sastava približno 8-9.
2. Farmaceutski sastav u skladu s patentnim zahtjevom 1 karakteriziran na način da je sastav vodeni gel i sadrži PVA i PEG polimere kao farmaceutski prihvatljive polimere, opcionalno zajedno s polisaharidom.
3. Farmaceutski sastav u skladu s patentnim zahtjevom 1 ili 2 karakteriziran na način da je čvrsti oblik pripravljen sušenjem, poželjno liofiliziranjem sastava iz patentnog zahtjeva 1 ili 2.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU0800031A HU0800031D0 (en) | 2008-01-16 | 2008-01-16 | Method for stabilization of s-nitrosoglutathione and composition prepared by the same |
| EP09702422.8A EP2252260B1 (en) | 2008-01-16 | 2009-01-16 | Method for stabilization of s-nitrosoglutathione and composition prepared by the same |
| PCT/HU2009/000004 WO2009090439A2 (en) | 2008-01-16 | 2009-01-16 | Method for stabilization of s-nitrosoglutathione and composition prepared by the same |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HRP20150578T1 true HRP20150578T1 (hr) | 2015-08-14 |
Family
ID=89988005
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HRP20150578TT HRP20150578T1 (hr) | 2008-01-16 | 2015-05-29 | Metoda za stabilizaciju s-nitrozoglutationa i sastav pripremljen tom metodom |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US8404266B2 (hr) |
| EP (1) | EP2252260B1 (hr) |
| JP (1) | JP5508286B2 (hr) |
| KR (1) | KR101601989B1 (hr) |
| CN (2) | CN101969922B (hr) |
| BR (1) | BRPI0906874A2 (hr) |
| CA (1) | CA2712299C (hr) |
| CY (1) | CY1116359T1 (hr) |
| DK (1) | DK2252260T3 (hr) |
| ES (1) | ES2538338T3 (hr) |
| HK (1) | HK1153944A1 (hr) |
| HR (1) | HRP20150578T1 (hr) |
| HU (2) | HU0800031D0 (hr) |
| PL (1) | PL2252260T3 (hr) |
| PT (1) | PT2252260E (hr) |
| WO (1) | WO2009090439A2 (hr) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK2197417T3 (da) * | 2007-10-17 | 2012-06-25 | Pharmagenix Ag | Farmaceutisk sammensætning, omfattende s-nitrosoglutathion og polysaccharid |
| CN101897948B (zh) * | 2010-07-16 | 2013-03-13 | 浙江大学 | 一种s-亚硝基谷胱甘肽的用途 |
| KR101555523B1 (ko) * | 2014-02-28 | 2015-09-25 | 부산대학교 산학협력단 | 산화질소 방출성 상처치료 필름 및 이의 제조방법 |
| CN106689132A (zh) * | 2016-12-30 | 2017-05-24 | 中国农业科学院麻类研究所 | 一种提高红麻幼苗期耐镉性能的组合物 |
| CN107823627A (zh) * | 2017-12-01 | 2018-03-23 | 成都卓阳生物科技有限公司 | 一种还原型谷胱甘肽在制备治疗糖尿病足涂沫药剂中的应用 |
| WO2019236825A1 (en) * | 2018-06-08 | 2019-12-12 | University Of Georgia Research Foundation, Inc. | Antimicrobial compositions with wound healing properties |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9504350D0 (en) * | 1995-03-04 | 1995-04-26 | Sod Conseils Rech Applic | Arginine derivatives |
| US20070185205A1 (en) * | 2000-01-14 | 2007-08-09 | Hunt John F | Airway Alkalinization as Therapy for Airway Diseases |
| WO2001070199A1 (en) | 2000-03-20 | 2001-09-27 | Novovascular, Inc. | Matrices containing nitric oxide donors and reducing agents and their use |
| US20020002136A1 (en) * | 2000-06-28 | 2002-01-03 | Hebert Rolland F. | Salts of glutathione |
| CN1531546A (zh) * | 2001-01-02 | 2004-09-22 | ����ҩƷ��ҵ��ʽ���� | 肽化合物 |
| ATE485849T1 (de) * | 2005-12-02 | 2010-11-15 | Univ Michigan | Polymerzusammensetzungen, überzüge und vorrichtungen und herstellungs- und anwendungsverfahren damit |
| DK2197417T3 (da) * | 2007-10-17 | 2012-06-25 | Pharmagenix Ag | Farmaceutisk sammensætning, omfattende s-nitrosoglutathion og polysaccharid |
-
2008
- 2008-01-16 HU HU0800031A patent/HU0800031D0/hu unknown
-
2009
- 2009-01-16 PL PL09702422T patent/PL2252260T3/pl unknown
- 2009-01-16 EP EP09702422.8A patent/EP2252260B1/en active Active
- 2009-01-16 JP JP2010542695A patent/JP5508286B2/ja not_active Expired - Fee Related
- 2009-01-16 KR KR1020107017003A patent/KR101601989B1/ko active IP Right Grant
- 2009-01-16 WO PCT/HU2009/000004 patent/WO2009090439A2/en active Application Filing
- 2009-01-16 BR BRPI0906874-0A patent/BRPI0906874A2/pt not_active Application Discontinuation
- 2009-01-16 ES ES09702422.8T patent/ES2538338T3/es active Active
- 2009-01-16 CA CA2712299A patent/CA2712299C/en active Active
- 2009-01-16 PT PT97024228T patent/PT2252260E/pt unknown
- 2009-01-16 CN CN2009801077972A patent/CN101969922B/zh not_active Expired - Fee Related
- 2009-01-16 DK DK09702422.8T patent/DK2252260T3/en active
- 2009-01-16 US US12/863,816 patent/US8404266B2/en active Active
- 2009-01-16 CN CN2013102937033A patent/CN103417973A/zh active Pending
- 2009-01-16 HU HUE09702422A patent/HUE025573T2/en unknown
-
2011
- 2011-08-09 HK HK11108321.0A patent/HK1153944A1/xx not_active IP Right Cessation
-
2015
- 2015-05-29 HR HRP20150578TT patent/HRP20150578T1/hr unknown
- 2015-06-03 CY CY20151100493T patent/CY1116359T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2009090439A2 (en) | 2009-07-23 |
| EP2252260A2 (en) | 2010-11-24 |
| EP2252260B1 (en) | 2015-03-04 |
| HK1153944A1 (en) | 2012-04-20 |
| PT2252260E (pt) | 2015-07-09 |
| DK2252260T3 (en) | 2015-06-08 |
| CY1116359T1 (el) | 2017-02-08 |
| JP5508286B2 (ja) | 2014-05-28 |
| US20110136910A1 (en) | 2011-06-09 |
| HU0800031D0 (en) | 2008-03-28 |
| HUE025573T2 (en) | 2016-04-28 |
| KR101601989B1 (ko) | 2016-03-09 |
| CA2712299C (en) | 2016-10-11 |
| US8404266B2 (en) | 2013-03-26 |
| CN101969922A (zh) | 2011-02-09 |
| JP2011509993A (ja) | 2011-03-31 |
| CN101969922B (zh) | 2013-07-10 |
| CA2712299A1 (en) | 2009-07-23 |
| BRPI0906874A2 (pt) | 2019-02-19 |
| KR20100127206A (ko) | 2010-12-03 |
| PL2252260T3 (pl) | 2015-08-31 |
| CN103417973A (zh) | 2013-12-04 |
| ES2538338T3 (es) | 2015-06-19 |
| WO2009090439A3 (en) | 2009-11-26 |
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