AR050036A1 - Anticuerpos anti - igf- ir y sus usos - Google Patents

Anticuerpos anti - igf- ir y sus usos

Info

Publication number
AR050036A1
AR050036A1 ARP050103179A ARP050103179A AR050036A1 AR 050036 A1 AR050036 A1 AR 050036A1 AR P050103179 A ARP050103179 A AR P050103179A AR P050103179 A ARP050103179 A AR P050103179A AR 050036 A1 AR050036 A1 AR 050036A1
Authority
AR
Argentina
Prior art keywords
antibodies
igf
igr
overexpression
receptor
Prior art date
Application number
ARP050103179A
Other languages
English (en)
Original Assignee
Pf Medicament
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34950307&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AR050036(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Pf Medicament filed Critical Pf Medicament
Publication of AR050036A1 publication Critical patent/AR050036A1/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2896Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/08Drugs for disorders of the urinary system of the prostate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies

Abstract

Se refiere a anticuerpos capaces de unirse específicamente al receptor IGF-IR del factor de crecimiento humano similar a la insulina y/o capaces de inhibir específicamente la actividad tirosin-quinasa de dicho IGF-IR, especialmente anticuerpos monoclonales de origen murino, quimérico o humanizado, así como las secuencias de los aminoácidos y secuencias de nucleotidos que codifiquen estos anticuerpos. La invencion también abarca el uso de estos anticuerpos como medicamento para el tratamiento profiláctico y/o terapéutico de cánceres que sobreexpresen IGF-IGR o cualquier patología conectada con la sobreexpresion de dicho receptor, así como los procesos o kits de diagnostico de enfermedades relacionadas con la sobreexpresion de IGF-IGR. La invencion finalmente comprende los productos y/o las composiciones que abarquen los mencionados anticuerpos en combinacion con anticuerpos anti-EGFR y/o anticuerpos anti-VEGF y/o anticuerpos dirigidos contra otros factores de crecimiento involucrados en la progresion del tumor o metástasis y/o compuestos y/o agentes anticancerígenos o agentes conjugados con toxinas y su uso para la prevencion y/o tratamiento de ciertos cánceres.
ARP050103179A 2004-07-29 2005-07-29 Anticuerpos anti - igf- ir y sus usos AR050036A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US59193204P 2004-07-29 2004-07-29
FR0408379A FR2873699B1 (fr) 2004-07-29 2004-07-29 Nouveaux anticorps anti igf ir rt leurs utilisations

Publications (1)

Publication Number Publication Date
AR050036A1 true AR050036A1 (es) 2006-09-20

Family

ID=34950307

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP050103179A AR050036A1 (es) 2004-07-29 2005-07-29 Anticuerpos anti - igf- ir y sus usos

Country Status (23)

Country Link
US (3) US7854930B2 (es)
EP (4) EP2365006A3 (es)
JP (3) JP5016487B2 (es)
KR (1) KR101220635B1 (es)
CN (2) CN103951752A (es)
AR (1) AR050036A1 (es)
AU (1) AU2005268505B2 (es)
BR (1) BRPI0513890A (es)
CA (1) CA2575348A1 (es)
CO (1) CO5700152A1 (es)
FR (1) FR2873699B1 (es)
GT (1) GT200500205A (es)
HK (1) HK1102600A1 (es)
IL (2) IL181025A (es)
MX (1) MX2007001109A (es)
NO (1) NO20071093L (es)
NZ (2) NZ569718A (es)
PA (1) PA8640601A1 (es)
RU (2) RU2406729C2 (es)
SV (1) SV2006002182A (es)
TW (1) TWI432451B (es)
WO (1) WO2006013472A2 (es)
ZA (1) ZA200700593B (es)

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CN101014625A (zh) 2007-08-08
IL181025A0 (en) 2007-07-04
RU2009138977A (ru) 2011-04-27
IL181025A (en) 2013-12-31
CA2575348A1 (en) 2006-02-09
US8420085B2 (en) 2013-04-16
FR2873699B1 (fr) 2009-08-21
IL229778A0 (en) 2014-01-30
SV2006002182A (es) 2006-10-04
NZ552821A (en) 2009-10-30
US20120183559A1 (en) 2012-07-19
ZA200700593B (en) 2008-05-28
RU2007107589A (ru) 2008-09-10
EP2365005A3 (en) 2011-10-26
HK1102600A1 (en) 2007-11-30
KR20070057814A (ko) 2007-06-07
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EP1771481A2 (en) 2007-04-11
TW200628490A (en) 2006-08-16
EP2365005A2 (en) 2011-09-14
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EP2380912A1 (en) 2011-10-26
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JP5016487B2 (ja) 2012-09-05
WO2006013472A3 (en) 2006-05-11
CO5700152A1 (es) 2006-11-30
US8124079B2 (en) 2012-02-28
AU2005268505A1 (en) 2006-02-09
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US7854930B2 (en) 2010-12-21
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CN103951752A (zh) 2014-07-30
RU2406729C2 (ru) 2010-12-20
CN101014625B (zh) 2013-07-03
AU2005268505B2 (en) 2011-11-17
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US20090214525A1 (en) 2009-08-27
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