AR041242A1 - Formulaciones farmaceuticas de modafinil y procesos para su preparacion - Google Patents
Formulaciones farmaceuticas de modafinil y procesos para su preparacionInfo
- Publication number
- AR041242A1 AR041242A1 ARP030103305A ARP030103305A AR041242A1 AR 041242 A1 AR041242 A1 AR 041242A1 AR P030103305 A ARP030103305 A AR P030103305A AR P030103305 A ARP030103305 A AR P030103305A AR 041242 A1 AR041242 A1 AR 041242A1
- Authority
- AR
- Argentina
- Prior art keywords
- processes
- preparation
- treatment
- modafinil
- pharmaceutical formulations
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
- A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Psychiatry (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Psychology (AREA)
- Obesity (AREA)
- Cardiology (AREA)
- Hospice & Palliative Care (AREA)
- Child & Adolescent Psychology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Pulmonology (AREA)
- Urology & Nephrology (AREA)
- Toxicology (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Composiciones de modafinilo, incluyendo composiciones de modafinilo y uno o más diluyentes, disgregantes, aglutinantes y lubricantes, y a los procesos para su preparación. Reivindicación 36: El método de la reivindicación 35, en el cual lacomposición se administra para el tratamiento de somnolencia, promoción del estado de vigilia, tratamiento de la enfermedad de Parkinson, isquemia cerebral, accidente cerebrovascular, apneas del sueno, trastornos de alimentación, estimulación delapetito y aumento de peso, tratamiento del trastorno de hiperactividad con déficit de atención y cansancio, y mejoría de la disfunción cognitiva.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10/243,557 US7229644B2 (en) | 2002-05-23 | 2002-09-13 | Pharmaceutical formulations of modafinil |
Publications (1)
Publication Number | Publication Date |
---|---|
AR041242A1 true AR041242A1 (es) | 2005-05-11 |
Family
ID=31991673
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP030103305A AR041242A1 (es) | 2002-09-13 | 2003-09-12 | Formulaciones farmaceuticas de modafinil y procesos para su preparacion |
Country Status (29)
Country | Link |
---|---|
US (1) | US7229644B2 (es) |
EP (1) | EP1556026B1 (es) |
JP (2) | JP5415662B2 (es) |
KR (1) | KR101125361B1 (es) |
CN (2) | CN101606915B (es) |
AR (1) | AR041242A1 (es) |
AT (1) | ATE434435T1 (es) |
AU (1) | AU2003270563B2 (es) |
BR (1) | BR0314515A (es) |
CA (1) | CA2498506C (es) |
CY (1) | CY1109465T1 (es) |
DE (1) | DE60328119D1 (es) |
DK (1) | DK1556026T3 (es) |
EA (1) | EA008506B1 (es) |
ES (1) | ES2325860T3 (es) |
HK (1) | HK1078265A1 (es) |
IL (1) | IL167187A (es) |
IS (1) | IS2707B (es) |
MX (1) | MXPA05002832A (es) |
MY (1) | MY140081A (es) |
NO (1) | NO333725B1 (es) |
NZ (1) | NZ538940A (es) |
PL (1) | PL375831A1 (es) |
PT (1) | PT1556026E (es) |
SI (1) | SI1556026T1 (es) |
TW (1) | TWI316406B (es) |
UA (1) | UA88867C2 (es) |
WO (1) | WO2004024133A1 (es) |
ZA (1) | ZA200502792B (es) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PT1309547E (pt) | 2000-07-27 | 2007-03-30 | Teva Pharma | Modafinil cristalino e puro, e processo para a sua preparação |
US20080058424A1 (en) * | 2002-05-23 | 2008-03-06 | Cephalon, Inc. | Novel pharmaceutical formulations of modafinil |
US7229644B2 (en) * | 2002-05-23 | 2007-06-12 | Cephalon, Inc. | Pharmaceutical formulations of modafinil |
US20040116532A1 (en) | 2002-09-13 | 2004-06-17 | Craig Heacock | Pharmaceutical formulations of modafinil |
FR2849029B1 (fr) | 2002-12-20 | 2005-03-18 | Lafon Labor | Procede de preparation et formes cristallines des enantiomeres optiques du modafinil. |
US20040253308A1 (en) * | 2003-04-29 | 2004-12-16 | Barr Laboratories, Inc. | Surface-treated modafinil particles |
AR046410A1 (es) * | 2003-09-18 | 2005-12-07 | Cephalon Inc | Composiciones farmaceuticas para la liberacion modificada de modafinilo |
US7368591B2 (en) | 2003-09-19 | 2008-05-06 | Cephalon France | Process for enantioselective synthesis of single enantiomers of modafinil by asymmetric oxidation |
US20050137264A1 (en) * | 2003-12-22 | 2005-06-23 | Patel Ashish A. | Modafinil compositions |
US20060024370A1 (en) | 2004-07-29 | 2006-02-02 | Cephalon France | Modafinil oral lyophilizate |
US8173169B2 (en) * | 2007-07-11 | 2012-05-08 | Hikma Pharmaceuticals | Formulation and process for the preparation of modafinil |
EP3002005A1 (en) * | 2014-09-30 | 2016-04-06 | Molkerei Meggle Wasserburg GmbH & Co. Kg | Direct compression excipient based on lactose, cellulose and starch |
US9616068B2 (en) | 2014-10-27 | 2017-04-11 | Pohela LLC | Animal training using cognitive enhancement |
FR3117775B1 (fr) * | 2020-12-18 | 2024-04-19 | Commissariat Energie Atomique | Produit pharmaceutique, son procédé de préparation et ses utilisations |
Family Cites Families (41)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US1570994A (en) | 1923-11-20 | 1926-01-26 | William A Cook | Spring-forming die |
GB1584462A (en) | 1977-03-31 | 1981-02-11 | Lafon Labor | N-diaryl-malonamide and diarylmethyl-sulphinyl-acetamide derivatives and pharmaceutical compositions containing them |
HU187215B (en) * | 1983-01-26 | 1985-11-28 | Egyt Gyogyszervegyeszeti Gyar | Method for producing pharmaceutical product of high actor content and prolonged effect |
FR2593809B1 (fr) * | 1986-01-31 | 1988-07-22 | Lafon Labor | Benzhydrylsulfinylacetamide, procede de preparation et utilisation en therapeutique |
FR2663225B1 (fr) | 1990-06-14 | 1994-11-04 | Lafon Labor | Nouvelle utilisation du modafinil. |
FR2684875B1 (fr) * | 1991-12-13 | 1995-05-24 | Lafon Labor | Utilisation du modafinil pour la fabrication d'un medicament ayant un effet anti-ischemique. |
FR2697162B1 (fr) | 1992-10-23 | 1995-01-13 | Lafon Labor | Utilisation du modafinil pour la fabrication d'un médicament pour le traitement de l'incontinence urinaire et des troubles sphinctériens urétro vésicaux. |
GB9225492D0 (en) * | 1992-12-05 | 1993-01-27 | Glaxo Group Ltd | Amine derivatives |
FR2702968B1 (fr) | 1993-03-23 | 1995-06-23 | Lafon Labor | Procédé de préparation de particules renfermant un ingrédient actif par extrusion et lyophilisation . |
US5843347A (en) | 1993-03-23 | 1998-12-01 | Laboratoire L. Lafon | Extrusion and freeze-drying method for preparing particles containing an active ingredient |
FR2706767B1 (es) | 1993-06-22 | 1995-09-08 | Lafon Labor | |
US5618845A (en) | 1994-10-06 | 1997-04-08 | Cephalon, Inc. | Acetamide derivative having defined particle size |
SI9500173B (sl) * | 1995-05-19 | 2002-02-28 | Lek, | Trofazna farmacevtska oblika s konstantnim in kontroliranim sproščanjem amorfne učinkovine za enkrat dnevno aplikacijo |
PT874631E (pt) * | 1996-01-19 | 2004-04-30 | Glaxo Group Ltd | Utilizacao de valaciclovir para a manufactura de um medicamento para o tratamento de herpes genital por aplicacao diaria unica |
JPH09208468A (ja) * | 1996-02-02 | 1997-08-12 | Dainippon Pharmaceut Co Ltd | p−クロロ−N−(2−モルホリノエチル)ベンズアミドを含有する錠剤 |
US5948437A (en) * | 1996-05-23 | 1999-09-07 | Zeneca Limited | Pharmaceutical compositions using thiazepine |
JPH10179045A (ja) * | 1996-12-25 | 1998-07-07 | Osaka Kagaku Gokin Kk | シート状可食性成形物 |
CN1277550A (zh) * | 1997-09-11 | 2000-12-20 | 尼科梅德丹麦有限公司 | 非甾体抗炎药物(NSAIDs)的改进释放的复合型组合物 |
FR2772615B1 (fr) * | 1997-12-23 | 2002-06-14 | Lipha | Comprime multicouche pour la liberation instantanee puis prolongee de substances actives |
SI20109A (sl) * | 1998-12-16 | 2000-06-30 | LEK, tovarna farmacevtskih in kemi�nih izdelkov, d.d. | Stabilna farmacevtska formulacija |
HUP0104606A3 (en) * | 1998-12-18 | 2003-01-28 | Basf Ag | A pharmaceutical mixture comprising a profen |
CN1335769A (zh) | 1998-12-18 | 2002-02-13 | 艾博特公司 | 双丙戊酸钠的控释制剂 |
US6294192B1 (en) | 1999-02-26 | 2001-09-25 | Lipocine, Inc. | Triglyceride-free compositions and methods for improved delivery of hydrophobic therapeutic agents |
US7374779B2 (en) | 1999-02-26 | 2008-05-20 | Lipocine, Inc. | Pharmaceutical formulations and systems for improved absorption and multistage release of active agents |
US6267985B1 (en) | 1999-06-30 | 2001-07-31 | Lipocine Inc. | Clear oil-containing pharmaceutical compositions |
US6248363B1 (en) | 1999-11-23 | 2001-06-19 | Lipocine, Inc. | Solid carriers for improved delivery of active ingredients in pharmaceutical compositions |
US20030104048A1 (en) | 1999-02-26 | 2003-06-05 | Lipocine, Inc. | Pharmaceutical dosage forms for highly hydrophilic materials |
US6346548B1 (en) | 1999-08-16 | 2002-02-12 | Cephalon, Inc. | Compositions including modafinil for treatment of attention deficit hyperactivity disorder and multiple sclerosis fatigue |
US6455588B1 (en) * | 1999-08-20 | 2002-09-24 | Cephalon, Inc. | Compositions including modafinil for treatment of eating disorders and for appetite stimulation |
US6204245B1 (en) * | 1999-09-17 | 2001-03-20 | The Regents Of The University Of California | Treatment of narcolepsy with immunosuppressants |
JP3888064B2 (ja) * | 2000-01-27 | 2007-02-28 | 田辺製薬株式会社 | 徐放性製剤およびその製法 |
US20010034373A1 (en) | 2000-02-09 | 2001-10-25 | Matthew Miller | Low dose modafinil for enhancement of cognitive function |
US6670358B2 (en) | 2000-05-16 | 2003-12-30 | Cephalon, Inc. | Substituted thioacetamides |
US6492396B2 (en) | 2000-05-16 | 2002-12-10 | Cephalon, Inc. | Substituted thioacetamides |
ES2317943T3 (es) | 2000-10-11 | 2009-05-01 | Cephalon, Inc. | Composiciones que comprenden compuestos de modafinilo. |
DE60219005T2 (de) | 2001-05-25 | 2007-12-13 | Cephalon, Inc. | Modafinil umfassende feste pharmazeutische Formulierungen |
US7576133B2 (en) | 2002-03-11 | 2009-08-18 | Carl Henry Lawyer | Methods and compositions for nasal administration of modafinil |
US7229644B2 (en) * | 2002-05-23 | 2007-06-12 | Cephalon, Inc. | Pharmaceutical formulations of modafinil |
US7115281B2 (en) | 2002-07-08 | 2006-10-03 | Ranbaxy Laboratories Limited | Processes for the preparation of oral dosage formulations of modafinil |
WO2004010979A1 (en) | 2002-07-25 | 2004-02-05 | Ranbaxy Laboratories Limited | Processes for the preparation of oral dosage formulations of modafinil |
US20040116532A1 (en) * | 2002-09-13 | 2004-06-17 | Craig Heacock | Pharmaceutical formulations of modafinil |
-
2002
- 2002-09-13 US US10/243,557 patent/US7229644B2/en not_active Expired - Fee Related
-
2003
- 2003-09-08 TW TW092124721A patent/TWI316406B/zh not_active IP Right Cessation
- 2003-09-09 MY MYPI20033411A patent/MY140081A/en unknown
- 2003-09-11 EA EA200500486A patent/EA008506B1/ru not_active IP Right Cessation
- 2003-09-11 CA CA2498506A patent/CA2498506C/en not_active Expired - Fee Related
- 2003-09-11 JP JP2004536511A patent/JP5415662B2/ja not_active Expired - Lifetime
- 2003-09-11 WO PCT/US2003/028528 patent/WO2004024133A1/en active Application Filing
- 2003-09-11 NZ NZ538940A patent/NZ538940A/en not_active IP Right Cessation
- 2003-09-11 BR BR0314515-8A patent/BR0314515A/pt not_active Application Discontinuation
- 2003-09-11 AU AU2003270563A patent/AU2003270563B2/en not_active Ceased
- 2003-09-11 MX MXPA05002832A patent/MXPA05002832A/es active IP Right Grant
- 2003-09-11 EP EP03752264A patent/EP1556026B1/en not_active Expired - Lifetime
- 2003-09-11 KR KR1020057004186A patent/KR101125361B1/ko not_active IP Right Cessation
- 2003-09-11 ES ES03752264T patent/ES2325860T3/es not_active Expired - Lifetime
- 2003-09-11 CN CN2009101401499A patent/CN101606915B/zh not_active Expired - Fee Related
- 2003-09-11 AT AT03752264T patent/ATE434435T1/de active
- 2003-09-11 SI SI200331620T patent/SI1556026T1/sl unknown
- 2003-09-11 CN CNB038217481A patent/CN100528150C/zh not_active Expired - Fee Related
- 2003-09-11 DE DE60328119T patent/DE60328119D1/de not_active Expired - Lifetime
- 2003-09-11 UA UAA200503450A patent/UA88867C2/ru unknown
- 2003-09-11 PL PL03375831A patent/PL375831A1/xx not_active Application Discontinuation
- 2003-09-11 DK DK03752264T patent/DK1556026T3/da active
- 2003-09-11 PT PT03752264T patent/PT1556026E/pt unknown
- 2003-09-12 AR ARP030103305A patent/AR041242A1/es unknown
-
2005
- 2005-02-24 IS IS7715A patent/IS2707B/is unknown
- 2005-03-01 IL IL167187A patent/IL167187A/en unknown
- 2005-03-03 NO NO20051138A patent/NO333725B1/no not_active IP Right Cessation
- 2005-11-14 HK HK05110183.1A patent/HK1078265A1/xx not_active IP Right Cessation
-
2006
- 2006-01-17 ZA ZA200502792A patent/ZA200502792B/en unknown
-
2009
- 2009-09-10 CY CY20091100942T patent/CY1109465T1/el unknown
-
2013
- 2013-09-18 JP JP2013193257A patent/JP2014028833A/ja active Pending
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
AR041242A1 (es) | Formulaciones farmaceuticas de modafinil y procesos para su preparacion | |
PL365181A1 (en) | Substituted thioacetamides | |
ATE524439T1 (de) | Thiosubstituierte arylmethansulfinylderivate | |
GT200500297A (es) | Sintesis asimetrica de dehidrobenzofuranos sustituidos | |
RU2016105971A (ru) | Применение флекаинида в качестве антиконнексинового средства и способ потенцирования эффектов психотропных лекарственных средств | |
ATE454372T1 (de) | Am histamin-h3-rezeptor wirksame mittel, herstellung und therapeutische anwendungen | |
PE20050255A1 (es) | Nuevas cianotiazolidas y procedimiento para su preparacion como medicamentos | |
BR0011251A (pt) | Composições de a-beta peptìdeo e processos para a produção das mesmas | |
CY1115875T1 (el) | Αντισωματα toy υποδοχεα 1 της ιντερφερονης αλφα και οι χρησεις αυτων | |
RU2008150621A (ru) | Лечение депрессивных расстройств | |
DK1303495T3 (da) | Substituerede 5-alkylnylpyrimidiner med neurotrofisk aktivitet | |
EA201200975A1 (ru) | Тиено[2,3-b]пиридиндионовые активаторы амфк и их терапевтическое применение | |
DOP2002000429A (es) | Imidazotriazinas | |
WO2007022437A3 (en) | Therapeutic agents for the treatment of cancer and metabolic disorders | |
NI200700010A (es) | Moduladores de los receptores de alfa 7 acetilcolina nicotinica y sus usos terapéuticos | |
ECSP088338A (es) | Terapia de combinación de oxazolidinonas sustituidas para la profilaxis y el tratamiento de alteraciones del flujo sanguíneo cerebral | |
AR069524A1 (es) | Derivados de isoxazolo - pirazina, un procedimiento para la preparacion del compuesto, medicamento en base al compuesto y uso del compuesto para preparar un medicamento | |
DOP2005000103A (es) | Derivados de tetrahidroisoquinolinsulfonamidas. | |
HUP0401201A2 (hu) | Flibanserin stabil polimorfja, ipari eljárás előállítására és alkalmazása gyógyszerek előállítására | |
GT200500291A (es) | Nuevos heterociclos | |
EA200601449A1 (ru) | Применение агомелатина для получения лекарственных средств, предназначенных для лечения нарушений сна у пациента с депрессией | |
NI200700032A (es) | Derivados arilsulfonilestilbeno para tratamiento de insomnio y afecciones relacionadas | |
NZ525236A (en) | Modafinil (C5H15NOS), 2- (benzhydryl-sulfinyl) acetamide, aka 2- [(diphenylmethyl) sulfinyl] acetamide in compositions of suspended particles, methods of preparation and uses thereof | |
EA200801302A1 (ru) | Композиции и способы лечения нарушений цнс | |
UY29618A1 (es) | " pirazolo(1,5-a) pirimidinas halogenadas, métodos, usos, composiciones e intermedios" |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FB | Suspension of granting procedure |