AR039783A1 - Metodos mejorados de purificacion viral - Google Patents

Metodos mejorados de purificacion viral

Info

Publication number
AR039783A1
AR039783A1 ARP030101504A ARP030101504A AR039783A1 AR 039783 A1 AR039783 A1 AR 039783A1 AR P030101504 A ARP030101504 A AR P030101504A AR P030101504 A ARP030101504 A AR P030101504A AR 039783 A1 AR039783 A1 AR 039783A1
Authority
AR
Argentina
Prior art keywords
virus
viruses
cell culture
improved methods
detergent
Prior art date
Application number
ARP030101504A
Other languages
English (en)
Original Assignee
Oncolytics Biotech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=29406789&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AR039783(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Oncolytics Biotech Inc filed Critical Oncolytics Biotech Inc
Publication of AR039783A1 publication Critical patent/AR039783A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/15—Reoviridae, e.g. calf diarrhea virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2720/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsRNA viruses
    • C12N2720/00011—Details
    • C12N2720/12011—Reoviridae
    • C12N2720/12051—Methods of production or purification of viral material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2720/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsRNA viruses
    • C12N2720/00011—Details
    • C12N2720/12011—Reoviridae
    • C12N2720/12211—Orthoreovirus, e.g. mammalian orthoreovirus
    • C12N2720/12222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2720/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsRNA viruses
    • C12N2720/00011—Details
    • C12N2720/12011—Reoviridae
    • C12N2720/12211—Orthoreovirus, e.g. mammalian orthoreovirus
    • C12N2720/12234—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2720/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsRNA viruses
    • C12N2720/00011—Details
    • C12N2720/12011—Reoviridae
    • C12N2720/12211—Orthoreovirus, e.g. mammalian orthoreovirus
    • C12N2720/12251—Methods of production or purification of viral material

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

Se refiere a un método mejorado de purificación de virus, en particular reovirus. Se pueden extraer virus infecciosos de un cultivo celular con un detergente para producir títulos virales más altos y el virus puede ser purificado luego mediante pasos simples tal como filtración y cromatografía en columna. También se proveen virus y composiciones que comprenden virus preparadas de acuerdo con la presente. Reivindicación 1: Un método para producir virus a partir de un cultivo de células, caracterizado porque comprende los pasos de: a) proveer un cultivo de células que ha sido infectado con el virus; b) extraer el virus de las células por adición de un detergente al cultivo e incubarlo por un período de tiempo para obtener un lisado celular; c) eliminar los desechos celulares; y d) recolectar el virus.
ARP030101504A 2002-04-30 2003-04-29 Metodos mejorados de purificacion viral AR039783A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US37727302P 2002-04-30 2002-04-30
US44317603P 2003-01-29 2003-01-29

Publications (1)

Publication Number Publication Date
AR039783A1 true AR039783A1 (es) 2005-03-02

Family

ID=29406789

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP030101504A AR039783A1 (es) 2002-04-30 2003-04-29 Metodos mejorados de purificacion viral

Country Status (17)

Country Link
US (3) US7223585B2 (es)
EP (1) EP1501921B2 (es)
JP (1) JP2005523722A (es)
AR (1) AR039783A1 (es)
AT (1) ATE427990T1 (es)
AU (1) AU2003229159B2 (es)
BR (1) BR0309659A (es)
CA (1) CA2482512C (es)
DE (1) DE60327069D1 (es)
DK (1) DK1501921T4 (es)
ES (1) ES2323454T5 (es)
HK (1) HK1070670A1 (es)
IL (1) IL164551A (es)
MX (1) MXPA04010603A (es)
NZ (1) NZ535944A (es)
TW (1) TWI317378B (es)
WO (1) WO2003093463A1 (es)

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Also Published As

Publication number Publication date
BR0309659A (pt) 2005-02-22
CA2482512A1 (en) 2003-11-13
US10167452B2 (en) 2019-01-01
DK1501921T3 (da) 2009-06-22
DE60327069D1 (de) 2009-05-20
US20040005693A1 (en) 2004-01-08
IL164551A (en) 2010-05-17
EP1501921B1 (en) 2009-04-08
US20140178969A1 (en) 2014-06-26
TW200401829A (en) 2004-02-01
DK1501921T4 (da) 2012-10-08
US8685734B2 (en) 2014-04-01
CA2482512C (en) 2011-09-20
ES2323454T5 (es) 2012-11-14
HK1070670A1 (en) 2005-06-24
ES2323454T3 (es) 2009-07-16
TWI317378B (en) 2009-11-21
NZ535944A (en) 2007-11-30
EP1501921A1 (en) 2005-02-02
AU2003229159B2 (en) 2008-02-21
US7223585B2 (en) 2007-05-29
ATE427990T1 (de) 2009-04-15
WO2003093463A1 (en) 2003-11-13
US20070269856A1 (en) 2007-11-22
MXPA04010603A (es) 2004-12-13
AU2003229159A1 (en) 2003-11-17
EP1501921B2 (en) 2012-07-25
IL164551A0 (en) 2005-12-18
JP2005523722A (ja) 2005-08-11

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