AR034679A1 - Derivados de aril (o heteroaril) azolilcarbinoles para el tratamiento de la incontinencia urinaria - Google Patents

Derivados de aril (o heteroaril) azolilcarbinoles para el tratamiento de la incontinencia urinaria

Info

Publication number
AR034679A1
AR034679A1 ARP020102482A ARP020102482A AR034679A1 AR 034679 A1 AR034679 A1 AR 034679A1 AR P020102482 A ARP020102482 A AR P020102482A AR P020102482 A ARP020102482 A AR P020102482A AR 034679 A1 AR034679 A1 AR 034679A1
Authority
AR
Argentina
Prior art keywords
treatment
urinary incontinence
derivatives
azolilcarbinoles
heteroaril
Prior art date
Application number
ARP020102482A
Other languages
English (en)
Original Assignee
Esteve Labor Dr
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Esteve Labor Dr filed Critical Esteve Labor Dr
Publication of AR034679A1 publication Critical patent/AR034679A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4196—1,2,4-Triazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A61K31/4155—1,2-Diazoles non condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/10—Drugs for disorders of the urinary system of the bladder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/12—Antidiuretics, e.g. drugs for diabetes insipidus

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Los derivados de arilo(o heteroarilo)azolilcarbinoles de fórmula general (1), en la cual Ar representa un radical fenilo o un radical tienilo, opcionalmente sustituidos; R1 representa un átomo de hidrógeno o un grupo alquilo inferior; R2 representa un radical dialquilaminoalquilo o azaheterociclilalquil; y Het representa un azol no sustituido u opcionalmente sustituido por uno ó dos sustituyentes; así como sus sales fisiológicas aceptables; son útiles como medicamentos en terapéutica humana y/o veterinaria para el tratamiento de la incontinencia urinaria, en mamíferos, incluido el hombre.
ARP020102482A 2001-07-06 2002-07-01 Derivados de aril (o heteroaril) azolilcarbinoles para el tratamiento de la incontinencia urinaria AR034679A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES200101587A ES2180449B1 (es) 2001-07-06 2001-07-06 Derivados de aril (o heteroaril) azolilcarbinoles para el tratamiento de la incontinencia urinaria.

Publications (1)

Publication Number Publication Date
AR034679A1 true AR034679A1 (es) 2004-03-03

Family

ID=8498326

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP020102482A AR034679A1 (es) 2001-07-06 2002-07-01 Derivados de aril (o heteroaril) azolilcarbinoles para el tratamiento de la incontinencia urinaria

Country Status (23)

Country Link
US (2) US20030022925A1 (es)
EP (1) EP1413305B1 (es)
JP (1) JP2004521150A (es)
KR (1) KR20040030788A (es)
CN (1) CN1543344A (es)
AR (1) AR034679A1 (es)
AT (1) ATE327752T1 (es)
BR (1) BR0211237A (es)
CA (1) CA2452646A1 (es)
CY (1) CY1105113T1 (es)
DE (1) DE60211913T2 (es)
DK (1) DK1413305T3 (es)
ES (2) ES2180449B1 (es)
MA (1) MA27056A1 (es)
MX (1) MXPA04000065A (es)
NO (1) NO20040031L (es)
NZ (1) NZ530817A (es)
PL (1) PL369062A1 (es)
PT (1) PT1413305E (es)
RU (1) RU2308268C2 (es)
UA (1) UA79238C2 (es)
WO (1) WO2003004022A1 (es)
ZA (1) ZA200400780B (es)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040142929A1 (en) * 2001-07-06 2004-07-22 Ramon Merce-Vidal Derivatives of aryl (or heteroaryl) azolylcarbinoles for the treatment of urinary incontinence
DE10335566A1 (de) * 2003-07-31 2005-02-24 Grünenthal GmbH Arzneimittel enthaltend Derivate von Aryl( oder Heteroaryl)azolylcarbinolen
TW200533657A (en) * 2004-02-17 2005-10-16 Esteve Labor Dr Substituted pyrazoline compounds, their preparation and use as medicaments
ES2244326B1 (es) * 2004-04-05 2007-02-16 Laboratorios Del Dr. Esteve, S.A. Combinacion de substancias activas.
EP1584335A3 (en) * 2004-04-05 2006-02-22 Laboratorios Del Dr. Esteve, S.A. Active substance combination comprising a carbinol composition and an opioid
US20060040924A1 (en) * 2004-06-22 2006-02-23 Laboratorios Dr. Esteve S.A. Derivatives of aryl (or heteroaryl) azolylcarbinols for the treatment of renal colic
WO2006010627A1 (en) * 2004-07-30 2006-02-02 Laboratorios Del Dr. Esteve, S.A. Aryl (or heteroaryl) azolylcarbinols
EP1743892A1 (en) * 2005-07-15 2007-01-17 Laboratorios del Dr. Esteve S.A. Substituted pyrazoline compounds, their preparation and use as medicaments
EP1743890A1 (en) * 2005-07-15 2007-01-17 Laboratorios Del Dr. Esteve, S.A. 4,5-Dihydro-1H-pyrazole derivatives, their preparation and use as medicaments
US7897589B2 (en) * 2005-07-15 2011-03-01 Laboratorios Del Dr. Esteve, S.A. Substituted pyrazoline compounds, their preparation and use as medicaments
EP1757587A1 (en) * 2005-07-15 2007-02-28 Laboratorios Del Dr. Esteve, S.A. Substituted pyrazoline compounds, their preparation and use as medicaments
US20070021485A1 (en) * 2005-07-22 2007-01-25 Gomis Antonio F Aryl (or heteroaryl) azolylcarbinols
ES2334548B1 (es) * 2005-07-29 2010-10-27 Laboratorios Del Dr. Esteve, S.A Forma de dosificacion de liberacion controlada de compuestos de pirazol para el tratamiento de la incontinencia urinaria.
US8722079B2 (en) 2008-04-18 2014-05-13 Warsaw Orthopedic, Inc. Methods for treating conditions such as dystonia and post-stroke spasticity with clonidine
EP2151234A1 (en) * 2008-07-28 2010-02-10 Laboratorios Del. Dr. Esteve, S.A. Pharmaceutical formulation comprising a CB1-receptor compound in a solid solution and/or solid dispersion
US20100291151A1 (en) * 2009-04-21 2010-11-18 Auspex Pharmaceuticals, Inc. 1-methylpyrazole modulators of substance p, calcitonin gene-related peptide, adrenergic receptor, and/or 5-ht receptor

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE891865A (fr) * 1981-01-30 1982-07-22 Sandoz Sa Nouveaux medicaments a base de derives condenses de l'imidazole pour le traitement des troubles urinaires
ES2150353B1 (es) * 1998-04-15 2001-07-01 Esteve Labor Dr Tienilazolilalcoxietanaminas, su preparacion y su aplicacion como medicamentos.
ES2137136B1 (es) * 1998-05-18 2000-07-01 Esteve Labor Dr Empleo de derivados de aril (o heteroaril) azolilcarbinoles en la elaboracion de un medicamento para el tratamiento de la inflamacion neurogenica.
ES2150378B1 (es) * 1998-08-07 2001-07-01 Esteve Labor Dr Empleo de derivados de aril(o heteroaril)azolilcarbinoles en la elaboracion de un medicamento para el tratamiento de los trastornos mediados por un exceso de substancia p.

Also Published As

Publication number Publication date
JP2004521150A (ja) 2004-07-15
RU2308268C2 (ru) 2007-10-20
KR20040030788A (ko) 2004-04-09
ES2180449B1 (es) 2004-01-16
RU2004103475A (ru) 2005-06-10
NZ530817A (en) 2005-07-29
PL369062A1 (en) 2005-04-18
NO20040031L (no) 2004-03-02
ES2263792T3 (es) 2006-12-16
ATE327752T1 (de) 2006-06-15
EP1413305B1 (en) 2006-05-31
US20030022925A1 (en) 2003-01-30
CA2452646A1 (en) 2003-01-16
BR0211237A (pt) 2004-08-10
DE60211913D1 (de) 2006-07-06
ZA200400780B (en) 2005-01-31
MXPA04000065A (es) 2004-05-21
EP1413305A1 (en) 2004-04-28
DK1413305T3 (da) 2006-09-18
MA27056A1 (fr) 2004-12-20
ES2180449A1 (es) 2003-02-01
CN1543344A (zh) 2004-11-03
UA79238C2 (en) 2007-06-11
CY1105113T1 (el) 2010-03-03
DE60211913T2 (de) 2007-05-24
US20050131049A1 (en) 2005-06-16
WO2003004022A1 (es) 2003-01-16
PT1413305E (pt) 2006-09-29

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Legal Events

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