AR029755A1 - Ditiepino (6,5-b) piridinas,analogos y drogas blandas de dichas piridinas, composicion farmaceutica que los comprende, usos de dosis de la composicion farmaceutica para la preparacion de medicamentos, aparato para la administracion de la composicion farmaceutica y procesos para la preparacion de dic - Google Patents
Ditiepino (6,5-b) piridinas,analogos y drogas blandas de dichas piridinas, composicion farmaceutica que los comprende, usos de dosis de la composicion farmaceutica para la preparacion de medicamentos, aparato para la administracion de la composicion farmaceutica y procesos para la preparacion de dicInfo
- Publication number
- AR029755A1 AR029755A1 ARP000102903A ARP000102903A AR029755A1 AR 029755 A1 AR029755 A1 AR 029755A1 AR P000102903 A ARP000102903 A AR P000102903A AR P000102903 A ARP000102903 A AR P000102903A AR 029755 A1 AR029755 A1 AR 029755A1
- Authority
- AR
- Argentina
- Prior art keywords
- preparation
- composition
- piridines
- pharmaceutical composition
- analogs
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/06—Anti-spasmodics, e.g. drugs for colics, esophagic dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/06—Antiabortive agents; Labour repressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pulmonology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Ophthalmology & Optometry (AREA)
- Gynecology & Obstetrics (AREA)
- Pregnancy & Childbirth (AREA)
- Vascular Medicine (AREA)
- Immunology (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Ditiepino [6,5-b]piridinas de las formulas (1) y (2) donde R1 a R9, m, n, y p tienen los significados que constan en la descripcion. Estos compuestos son utiles como antagonistas del canal de calcio, con actividad cardiovascular, antiasmática y antibroncoconstrictiva. Composiciones farmacéuticas así como también usos de dosis de dichas composiciones farmacéuticas para la preparacion de medicamentos para la prevencion y tratamiento de desordenes tales como hipersensibilidad, alergia, asma, broncoespasmo, dismenorrea, espasmo esofagal, glaucoma, parto prematuro, desordenes del tracto urinario, desordenes de la motilidad gastrointestinal y desordenes cardiovasculares. También se dan a conocer un aparato para la administracion de dichas composiciones farmacéuticas y procesos para la preparacion de dichas piridinas y de dichos análogos.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US13898799P | 1999-06-14 | 1999-06-14 | |
US09/580,882 US6291454B1 (en) | 1999-06-14 | 2000-05-30 | Dithiepino[6,5-b]pyridines, and related compositions and methods |
Publications (1)
Publication Number | Publication Date |
---|---|
AR029755A1 true AR029755A1 (es) | 2003-07-16 |
Family
ID=22484608
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP000102903A AR029755A1 (es) | 1999-06-14 | 2000-06-13 | Ditiepino (6,5-b) piridinas,analogos y drogas blandas de dichas piridinas, composicion farmaceutica que los comprende, usos de dosis de la composicion farmaceutica para la preparacion de medicamentos, aparato para la administracion de la composicion farmaceutica y procesos para la preparacion de dic |
Country Status (23)
Country | Link |
---|---|
US (4) | US6291454B1 (es) |
EP (1) | EP1192163B1 (es) |
JP (1) | JP2003502335A (es) |
KR (1) | KR20020027350A (es) |
CN (1) | CN1160359C (es) |
AR (1) | AR029755A1 (es) |
AT (1) | ATE250067T1 (es) |
AU (1) | AU771033B2 (es) |
BR (1) | BR0012215A (es) |
CA (1) | CA2375878A1 (es) |
CZ (1) | CZ20014518A3 (es) |
DE (1) | DE60005349T2 (es) |
DK (1) | DK1192163T3 (es) |
ES (1) | ES2207523T3 (es) |
HK (1) | HK1049485B (es) |
HU (1) | HUP0201566A3 (es) |
IL (1) | IL147128A0 (es) |
MX (1) | MXPA01013008A (es) |
MY (1) | MY128062A (es) |
PL (1) | PL352909A1 (es) |
PT (1) | PT1192163E (es) |
RU (1) | RU2230746C2 (es) |
WO (1) | WO2000077009A1 (es) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK1200446T3 (da) * | 1999-07-12 | 2005-10-24 | Ortho Mcneil Pharm Inc | Oxathiepino[6,5-b]dihydropyridiner og beslægtede forbindelser og fremgangsmåder |
US6472530B1 (en) | 1999-09-22 | 2002-10-29 | Ortho-Mcneil Pharmaceutical, Inc. | Benzo-fused dithiepino[6,5-b]pyridines, and related compositions and methods |
AU783470B2 (en) | 2000-01-12 | 2005-10-27 | Ortho-Mcneil Pharmaceutical, Inc. | Benzosulfones with calcium antagonist activity |
US6410552B1 (en) | 2000-01-27 | 2002-06-25 | Ortho-Mcneil Pharmaceutical, Inc. | Benzoether and related compositions and methods |
KR200451743Y1 (ko) * | 2008-03-25 | 2011-01-10 | 이영수 | 줄넘기용 줄 길이 조절장치 |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2397431A1 (fr) * | 1977-07-12 | 1979-02-09 | Ugine Kuhlmann | Procede de fabrication de copolymeres greffes par polymerisation-greffage en emulsion-suspension |
US4285955A (en) | 1978-10-31 | 1981-08-25 | Bayer Aktiengesellschaft | 1,4-Dihydropyridinecarboxylic acids |
US4483985A (en) | 1978-10-31 | 1984-11-20 | Bayer Aktiengesellschaft | Production of 1,4-dihydropyridinecarboxylic acids |
NZ201395A (en) | 1981-07-30 | 1987-02-20 | Bayer Ag | Pharmaceutical compositions containing 1,4-dihydropyridines and certain of these dihydropyridines |
JPS58201764A (ja) | 1982-05-17 | 1983-11-24 | Maruko Seiyaku Kk | ジヒドロピリジン誘導体 |
JPS61293972A (ja) | 1985-06-24 | 1986-12-24 | Nisshin Flour Milling Co Ltd | 1,4−ジヒドロピリジンスルホン誘導体およびその製法 |
US4845225A (en) * | 1986-04-09 | 1989-07-04 | Ortho Pharmaceutical Corporation | Substituted thiacycloalkeno [3,2-b] pyridines |
IT1204948B (it) * | 1987-03-13 | 1989-03-10 | Boheringer Biochemia Robin S P | 2-tiometil-sostituite-piridine, metodo per la loro preparazione e composizioni farmaceutiche che le contengono. |
US4889866A (en) | 1987-06-11 | 1989-12-26 | Syntex (U.S.A.) Inc. | Arylsulfonyl dihydropyridine derivatives |
US4879384A (en) * | 1988-06-15 | 1989-11-07 | Ortho Pharmaceutical Corporation | Preparation of thiocycloalkno [3,2-b] pyridines |
US5075440A (en) | 1990-05-03 | 1991-12-24 | Ortho Pharmaceutical Corporation | Novel pyrido[2,3-f](1,4)thiazepines and pyrido[3,2-b](1,5)benzothiazepines |
DE19532320A1 (de) | 1995-09-01 | 1997-03-06 | Bayer Ag | Verfahren zur Herstellung von optisch aktiven ortho-substituierten 4-Aryl-Dihydropyridinen |
-
2000
- 2000-05-30 ES ES00939382T patent/ES2207523T3/es not_active Expired - Lifetime
- 2000-05-30 DK DK00939382T patent/DK1192163T3/da active
- 2000-05-30 HU HU0201566A patent/HUP0201566A3/hu unknown
- 2000-05-30 DE DE60005349T patent/DE60005349T2/de not_active Expired - Fee Related
- 2000-05-30 AU AU54473/00A patent/AU771033B2/en not_active Ceased
- 2000-05-30 JP JP2001503866A patent/JP2003502335A/ja active Pending
- 2000-05-30 PL PL00352909A patent/PL352909A1/xx unknown
- 2000-05-30 CZ CZ20014518A patent/CZ20014518A3/cs unknown
- 2000-05-30 CA CA002375878A patent/CA2375878A1/en not_active Abandoned
- 2000-05-30 EP EP00939382A patent/EP1192163B1/en not_active Expired - Lifetime
- 2000-05-30 IL IL14712800A patent/IL147128A0/xx not_active IP Right Cessation
- 2000-05-30 WO PCT/US2000/014715 patent/WO2000077009A1/en not_active Application Discontinuation
- 2000-05-30 CN CNB008116970A patent/CN1160359C/zh not_active Expired - Fee Related
- 2000-05-30 AT AT00939382T patent/ATE250067T1/de not_active IP Right Cessation
- 2000-05-30 US US09/580,882 patent/US6291454B1/en not_active Expired - Lifetime
- 2000-05-30 MX MXPA01013008A patent/MXPA01013008A/es active IP Right Grant
- 2000-05-30 KR KR1020017016128A patent/KR20020027350A/ko not_active Application Discontinuation
- 2000-05-30 PT PT00939382T patent/PT1192163E/pt unknown
- 2000-05-30 BR BR0012215-7A patent/BR0012215A/pt not_active IP Right Cessation
- 2000-05-30 RU RU2002100354/04A patent/RU2230746C2/ru not_active IP Right Cessation
- 2000-06-13 AR ARP000102903A patent/AR029755A1/es not_active Application Discontinuation
- 2000-06-14 MY MYPI20002669A patent/MY128062A/en unknown
-
2001
- 2001-05-07 US US09/850,303 patent/US20020103376A1/en not_active Abandoned
- 2001-06-13 US US09/880,565 patent/US20020032332A1/en not_active Abandoned
- 2001-07-23 US US09/911,050 patent/US20020026051A1/en not_active Abandoned
-
2003
- 2003-03-05 HK HK03101638.3A patent/HK1049485B/zh not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
DE60005349T2 (de) | 2004-12-30 |
DE60005349D1 (de) | 2003-10-23 |
EP1192163A1 (en) | 2002-04-03 |
CN1370175A (zh) | 2002-09-18 |
US20020026051A1 (en) | 2002-02-28 |
CN1160359C (zh) | 2004-08-04 |
US20020103376A1 (en) | 2002-08-01 |
PT1192163E (pt) | 2004-01-30 |
MY128062A (en) | 2007-01-31 |
US6291454B1 (en) | 2001-09-18 |
ATE250067T1 (de) | 2003-10-15 |
AU5447300A (en) | 2001-01-02 |
US20020032332A1 (en) | 2002-03-14 |
CA2375878A1 (en) | 2000-12-21 |
WO2000077009A1 (en) | 2000-12-21 |
JP2003502335A (ja) | 2003-01-21 |
HK1049485B (zh) | 2005-04-29 |
HUP0201566A2 (en) | 2002-08-28 |
DK1192163T3 (da) | 2003-12-08 |
CZ20014518A3 (cs) | 2003-02-12 |
KR20020027350A (ko) | 2002-04-13 |
PL352909A1 (en) | 2003-09-22 |
MXPA01013008A (es) | 2003-06-24 |
IL147128A0 (en) | 2002-08-14 |
HK1049485A1 (en) | 2003-05-16 |
BR0012215A (pt) | 2002-07-02 |
EP1192163B1 (en) | 2003-09-17 |
RU2230746C2 (ru) | 2004-06-20 |
AU771033B2 (en) | 2004-03-11 |
HUP0201566A3 (en) | 2004-03-01 |
ES2207523T3 (es) | 2004-06-01 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
NO20060865L (no) | Indol-5-YL sulfonamid derivater, deres fremstilling og deres anvedelse 5-HT-6 som modulatorer | |
GT199800046A (es) | Compuestos de pirazina. | |
AR029011A1 (es) | Tiazoles e imidazo[4,5-b]piridinas, un proceso para su produccion, una composicion farmaceutica y el uso de dicho compuesto para la fabricacion de un medicamento | |
NO20060682L (no) | Indol-6 sulfonamid derivater, deres fremstilling og deres anvendelse 5-HT-6 som modulatorer | |
AR003440A1 (es) | Nuevos derivados de aminoacidos, formulacion farmaceutica que los contiene, uso de dichos derivados para preparar medicamentos y procedimiento para la preparacion de dichos derivados. | |
AR025959A1 (es) | DERIVADOS DE TER.-BUTIL-(7-METIL-IMIDAZO[1,2,a]PIRIDIN-3-IL)-AMINA, PROCEDIMIENTO PARA SU PREPARACION, MEDICAMENTOS QUE LOS CONTIENEN, SU USO PARA LAPREPARACION DE UN MEDICAMENTO PARA LA INHIBICION DE NO-SINTASA Y COMPOSICIONES FARMACEUTICAS QUE LOS CONTIENEN | |
AR028833A1 (es) | Compuestos inhibidores de metaloproteasas, composiciones farmaceuticas, uso para la manufactura de medicamentos, metodo de tratamiento y procedimiento para su preparacion | |
ES2160525B1 (es) | Derivados de la 4-aroilpiperidina antagonistas de los receptores ccr-3 | |
AR033367A1 (es) | Derivados de imidazopirimidina y derivados de triazolopirimidina, un procedimiento para su preparacion, medicamentos, una composicion farmaceutica, y uso de dichos derivados para la preparacion de medicamentos | |
GT199900063A (es) | Mesilato de n-(3-etinilfenilamino) -6, 7 -bis (2-metoxietoxi)-4-quinazolinamina anhidro y monohidratado. | |
MX9300407A (es) | Derivados azabiciclicos usados en la fabricacion de medicamentos, composiciones que los contienen y procedimiento para su preparacion. | |
UY28343A1 (es) | Derivados de 2-amino-piridina utiles para el tratamiento de enfermedades | |
HK1080764A1 (en) | Implant for transport and release for pharmacologically active agents as well as a process for producing the same | |
AR022423A1 (es) | Compuestos derivados de acidos 2,3,4,5-tetrahidro-1h-[1,4]benzodiazepina-3-hidroxamicos, composicion farmaceutica que los comprenden, y el uso de losmismos para la manufactura de un medicamento | |
AR004480A1 (es) | Compuestos de ascomicina que poseen actividad antiinflamatoria, pro cedimiento para prepararlos, uso de dichos compuestos para preparar agentesfarmaceuticos y composiciones farmaceuticas que los incluyen | |
AR029755A1 (es) | Ditiepino (6,5-b) piridinas,analogos y drogas blandas de dichas piridinas, composicion farmaceutica que los comprende, usos de dosis de la composicion farmaceutica para la preparacion de medicamentos, aparato para la administracion de la composicion farmaceutica y procesos para la preparacion de dic | |
ID29025A (id) | Fenilalkenoilguanidina-fenilalkenoilguanidina yang disubstitusi asam empedu, proses pembuatannya, penggunaannya sebagai obat atau diaknostik dan obat-obat yang mengandungnya | |
AR005102A1 (es) | Compuestos derivados de octahidro-pirrolo [1,2-a]-pirazina 2,7-sustituidos, composiciones farmaceuticas y uso de dichos compuestos para la fabricacion deun medicamento. | |
NO20060506L (no) | Indol-7-yl sulfonamid derivater, deres fremstilling og deres anvendelse i medikamenter | |
TW200740440A (en) | Novel combinations of medicaments for the treatment of respiratory diseases containing long-acting beta-agonists and at least one additional active ingredient | |
HUP0104002A2 (hu) | alfa2-Antagonista triciklusos delta3-piperidinek, eljárás előállításukra, ilyen vegyületeket tartalmazó gyógyászati készítmények és alkalmazásuk gyógyszerként | |
AR022405A1 (es) | Derivados de acido piroglutamico y compuestos relacionados que inhiben la adhesion de leucocitos intermediada por vla-4, composiciones farmaceuticas y eluso de los mismos para la manufactura de agentes y de medicamentos | |
AR024411A1 (es) | Polimorfos de un diclorhidrato cristalino de azobiciclo[2.2.2]oct-3-ilamina y sus composiciones farmaceuticas. | |
MY139613A (en) | Novel piperazinyl-pyrazinone derivatives for the treatment of 5-ht2a receptor-related disorders | |
BRPI0412928A (pt) | dibenzo[b,f]oxepina-10-carboxamidas e usos farmacêuticos das mesmas |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FA | Abandonment or withdrawal |