AR029729A1 - Derivados de polifluoroalquiltriazol, su preparacion y su utilizacion en terapeutica - Google Patents

Derivados de polifluoroalquiltriazol, su preparacion y su utilizacion en terapeutica

Info

Publication number
AR029729A1
AR029729A1 ARP010103375A ARP010103375A AR029729A1 AR 029729 A1 AR029729 A1 AR 029729A1 AR P010103375 A ARP010103375 A AR P010103375A AR P010103375 A ARP010103375 A AR P010103375A AR 029729 A1 AR029729 A1 AR 029729A1
Authority
AR
Argentina
Prior art keywords
therapeutics
group
polifluoroalquiltriazol
derivatives
preparation
Prior art date
Application number
ARP010103375A
Other languages
English (en)
Original Assignee
Sanofi Synthelabo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Synthelabo filed Critical Sanofi Synthelabo
Publication of AR029729A1 publication Critical patent/AR029729A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C07D249/10—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D249/12—Oxygen or sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Compuesto de formula general 1 en la cual R1 es un grupo de formula CnHxFy, donde n =1 o 2 , x = 0 a 4, y = 1 a 5 y x + y = 2n + 1; R representa un grupo alquenilo, fenilo, tienilo, furilo, piridilo, imidazolilo, tiazolilo, piranilo o dihidropiranilo C2-4, eventualmente sustituido por uno o dos grupos R3; R2 y R3 representan independientemente entre sí, un átomo de hidrogeno, un átomo de halogeno, un grupo alquilo C1-4, alcoxi C1-4, un hidroxi un amino, un ciano, un nitro, un alquiltio C1-4, un SO2NH2 o un hidroximetilo; y sus sales N-oxidos e hidratos. Aplicacion en terapéutica, como antagonistas de receptores 5-HT4 y M3. También se reivindica compuestos intermediarios.
ARP010103375A 2000-07-18 2001-07-16 Derivados de polifluoroalquiltriazol, su preparacion y su utilizacion en terapeutica AR029729A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0009418A FR2811989A1 (fr) 2000-07-18 2000-07-18 Derives de polyfluoroalkytriazole, leur preparation et leur application en therapeutique

Publications (1)

Publication Number Publication Date
AR029729A1 true AR029729A1 (es) 2003-07-10

Family

ID=8852646

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP010103375A AR029729A1 (es) 2000-07-18 2001-07-16 Derivados de polifluoroalquiltriazol, su preparacion y su utilizacion en terapeutica

Country Status (4)

Country Link
AR (1) AR029729A1 (es)
AU (1) AU2001284084A1 (es)
FR (1) FR2811989A1 (es)
WO (1) WO2002006272A1 (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR039385A1 (es) 2002-04-19 2005-02-16 Astrazeneca Ab Derivados de tioxantina como inhibidores de la mieloperoxidasa
FR2846559B1 (fr) 2002-10-31 2007-06-15 Centre Nat Rech Scient Composition pharmaceutique pour la preparation d'un medicament destine a traiter et/ou a prevenir une pathologie liee a une conduite obsessionnelle
MY140748A (en) 2004-12-06 2010-01-15 Astrazeneca Ab Novel pyrrolo [3,2-d] pyrimidin-4-one derivatives and their use in therapy
TW200804383A (en) 2006-06-05 2008-01-16 Astrazeneca Ab New compounds
US20160311826A1 (en) 2013-12-11 2016-10-27 Ironwood Pharmaceuticals, Inc. Sgc stimulators
CN117143013A (zh) * 2023-11-01 2023-12-01 苏州开元民生科技股份有限公司 一种2-氯烟酸的合成方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4225778A1 (de) * 1992-08-04 1994-02-17 Hoechst Ag 1,2,4-Triazolyl-3-carbonsäure-4-aminopiperidide, Verfahren zu ihrer Herstellung, sie enthaltende Mittel und ihre Verwendung als Schädlingsbekämpfungsmittel, insbesondere Fungizide
FR2751647B1 (fr) * 1996-07-25 1998-09-11 Synthelabo Derives de benzimidazole, leurs preparations et leurs applications en therapeutique
FR2766485B1 (fr) * 1997-07-23 2002-05-24 Synthelabo Derives de 2,4-dihydro-3h-1,2,4-triazol-3-one, leur prparation et leur application en therapeutique
FR2789077A1 (fr) * 1999-02-02 2000-08-04 Synthelabo Derives de perazole, leur preparation et leur application en therapeutique

Also Published As

Publication number Publication date
AU2001284084A1 (en) 2002-01-30
WO2002006272A1 (fr) 2002-01-24
FR2811989A1 (fr) 2002-01-25

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