AR028813A1 - Un compuesto derivado de piperidina su utilizacion procedimientos para prepararlo una composicion farmaceutica que lo comprende y un compuesto util como intermediario para preparar dicho compuesto derivado de piperidina - Google Patents
Un compuesto derivado de piperidina su utilizacion procedimientos para prepararlo una composicion farmaceutica que lo comprende y un compuesto util como intermediario para preparar dicho compuesto derivado de piperidinaInfo
- Publication number
- AR028813A1 AR028813A1 ARP000100555A ARP000100555A AR028813A1 AR 028813 A1 AR028813 A1 AR 028813A1 AR P000100555 A ARP000100555 A AR P000100555A AR P000100555 A ARP000100555 A AR P000100555A AR 028813 A1 AR028813 A1 AR 028813A1
- Authority
- AR
- Argentina
- Prior art keywords
- piperidine
- prepare
- compound
- compound derived
- intermediary
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/34—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/26—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Pain & Pain Management (AREA)
- Urology & Nephrology (AREA)
- Pulmonology (AREA)
- Cardiology (AREA)
- Psychiatry (AREA)
- Rheumatology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hospice & Palliative Care (AREA)
- Otolaryngology (AREA)
- Dermatology (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Hydrogenated Pyridines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
Compuestos de formula 1 así como a sus sales con ácidos minerales u orgánicos, sus solvatos y/o sus hidratos, que presentan una fuerte afinidad y una gran selectividad para los receptores NK1 humanos de la Sustancia P. Los sustituyentes X, Ar y R1 son tal como figuran en la memoria descriptiva. Se refiere también a su procedimiento de preparacion, los compuestos intermedios de formula (7) utiles para la preparacion, las composiciones farmacéuticas que los contienen y su utilizacion para la fabricacion de medicamentos destinados a tratar toda clase de patología donde la Sustancia P, y los receptores NK1 humanos están implicados.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9901593A FR2789389B3 (fr) | 1999-02-10 | 1999-02-10 | Nouveaux derives de piperidine, procede pour leur obtention et compositions pharmaceutiques les contenant |
FR9904429A FR2789390B3 (fr) | 1999-02-10 | 1999-04-07 | Nouveaux derives de piperidine, procede pour leur obtention et compositions pharmaceutiques les contenant |
Publications (1)
Publication Number | Publication Date |
---|---|
AR028813A1 true AR028813A1 (es) | 2003-05-28 |
Family
ID=26234812
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP000100555A AR028813A1 (es) | 1999-02-10 | 2000-02-09 | Un compuesto derivado de piperidina su utilizacion procedimientos para prepararlo una composicion farmaceutica que lo comprende y un compuesto util como intermediario para preparar dicho compuesto derivado de piperidina |
Country Status (37)
Country | Link |
---|---|
US (2) | US6642233B1 (es) |
EP (1) | EP1150970B1 (es) |
JP (1) | JP4648544B2 (es) |
KR (1) | KR100611261B1 (es) |
CN (1) | CN1273463C (es) |
AR (1) | AR028813A1 (es) |
AT (1) | ATE370942T1 (es) |
AU (1) | AU763716B2 (es) |
BG (1) | BG65031B1 (es) |
BR (1) | BR0008067A (es) |
CA (1) | CA2360894C (es) |
CO (1) | CO4980896A1 (es) |
CZ (1) | CZ300765B6 (es) |
DE (1) | DE60036081T2 (es) |
DK (1) | DK1150970T3 (es) |
EE (1) | EE04437B1 (es) |
ES (1) | ES2291187T3 (es) |
FR (1) | FR2789390B3 (es) |
HK (1) | HK1038927A1 (es) |
HR (1) | HRP20010566A2 (es) |
HU (1) | HUP0201281A3 (es) |
ID (1) | ID29219A (es) |
IL (2) | IL144363A0 (es) |
ME (1) | MEP11908A (es) |
NO (2) | NO321149B1 (es) |
NZ (1) | NZ513053A (es) |
PE (1) | PE20001463A1 (es) |
PL (1) | PL198561B1 (es) |
PT (1) | PT1150970E (es) |
RS (1) | RS50210B (es) |
RU (1) | RU2220956C2 (es) |
SI (1) | SI1150970T1 (es) |
SK (1) | SK286401B6 (es) |
TR (1) | TR200102331T2 (es) |
TW (1) | TWI254712B (es) |
UA (1) | UA70986C2 (es) |
WO (1) | WO2000047572A1 (es) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2003217535A1 (en) * | 2002-02-20 | 2003-09-09 | Sepracor Inc. | Carbonate and carbamate modified forms of glucocorticoids |
US20050009798A1 (en) * | 2002-02-20 | 2005-01-13 | Sepracor Inc. | Carbonate and carbamate modified forms of glucocorticoids in combination with B2 adrenergic agonists |
US20070129328A1 (en) * | 2004-01-30 | 2007-06-07 | BOETTNER Wayne | Pharmaceutical compositions of neurokinin receptor antagonists and cyclodextrin and methods for improved injection site toleration |
FR2873373B1 (fr) * | 2004-07-23 | 2006-09-08 | Sanofi Synthelabo | Derives de 4-arylmorpholin-3-one, leur preparation et leur application en therapeutique |
GB2452696B (en) * | 2007-08-02 | 2009-09-23 | Cambridge Entpr Ltd | 3-(2',2'-dimethylpropanoylamino)-tetrahydropyridin-2-one and its use in pharmaceutical compositions |
DE102008015428A1 (de) * | 2008-03-20 | 2009-09-24 | Beiersdorf Ag | Kühlende Zubereitungen für den humanen Haut- und/oder Schleimhautkontakt mit einem Gehalt an (1R,2S,5R)-2-Isopropyl-5-methyl-N-(2-(pyridin-2-yl)ethyl-cyclohexancarboxamid und/oder (1R,2S,5R)-N-(4-(Cyanomethyl)-phenyl)-2-isopropyl-5-methylcyclohexancarboxamid |
DE102008015425A1 (de) * | 2008-03-20 | 2010-01-21 | Beiersdorf Ag | Kosmetische oder dermatologische Zubereitungen zur Verringerung von Juckreiz und anderen dermatologischen Missempfindungen, die insbesondere bei Altershaut auftreten können, mit einem Gehalt an (1R,2S,5R)-2-Isopropyl-5-methyl-N-(2-(pyridin-2-yl)ethyl-cyclohexancarboxamid und/oder (1R,2S,5R)-N-(4-(Cyanomethyl)-phenyl)-2-isopropyl-5-methylcyclohexancarboxamid |
DE102008015426A1 (de) * | 2008-03-20 | 2009-09-24 | Beiersdorf Ag | Kühlende kosmetische oder dermatologische Zubereitungen mit einem Gehalt an (1R,2S,5R)-2-Isopropyl-5-methyl-N-(2-(pyridyn-2-yl)ethyl-cyclohexancarboxamid und/oder (1R,2S,5R)-N-(4-(Cyanomethyl)-phenyl)-2-isopropyl-5-methylcyclohexancarboxamid zu Reduktion von Hautrötungen |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US512901A (en) * | 1894-01-16 | Folding bed | ||
GB821012A (en) * | 1957-01-15 | 1959-09-30 | Rhone Poulenc Sa | New phenthiazine derivatives and processes for their preparation |
FR2676055B1 (fr) | 1991-05-03 | 1993-09-03 | Sanofi Elf | Composes polycycliques amines et leurs enantiomeres, procede pour leur preparation et compositions pharmaceutiques les contenant. |
CN1067385C (zh) | 1994-08-25 | 2001-06-20 | 默里尔药物公司 | 用于治疗变应性疾病的新的取代的哌啶类化合物 |
EP0714891A1 (en) * | 1994-11-22 | 1996-06-05 | Eli Lilly And Company | Heterocyclic tachykinin receptor antagonists |
-
1999
- 1999-04-07 FR FR9904429A patent/FR2789390B3/fr not_active Expired - Lifetime
-
2000
- 2000-02-08 HU HU0201281A patent/HUP0201281A3/hu unknown
- 2000-02-08 RS YUP-564/01A patent/RS50210B/sr unknown
- 2000-02-08 NZ NZ513053A patent/NZ513053A/xx not_active IP Right Cessation
- 2000-02-08 WO PCT/FR2000/000284 patent/WO2000047572A1/fr active IP Right Grant
- 2000-02-08 ID IDW00200101651A patent/ID29219A/id unknown
- 2000-02-08 CN CNB008058261A patent/CN1273463C/zh not_active Expired - Fee Related
- 2000-02-08 EE EEP200100417A patent/EE04437B1/xx not_active IP Right Cessation
- 2000-02-08 PL PL350243A patent/PL198561B1/pl not_active IP Right Cessation
- 2000-02-08 CZ CZ20012888A patent/CZ300765B6/cs not_active IP Right Cessation
- 2000-02-08 AU AU25531/00A patent/AU763716B2/en not_active Ceased
- 2000-02-08 BR BR0008067-5A patent/BR0008067A/pt not_active Application Discontinuation
- 2000-02-08 UA UA2001075184A patent/UA70986C2/uk unknown
- 2000-02-08 RU RU2001121989/04A patent/RU2220956C2/ru not_active IP Right Cessation
- 2000-02-08 SK SK1139-2001A patent/SK286401B6/sk not_active IP Right Cessation
- 2000-02-08 IL IL14436300A patent/IL144363A0/xx not_active IP Right Cessation
- 2000-02-08 PT PT00903744T patent/PT1150970E/pt unknown
- 2000-02-08 ME MEP-119/08A patent/MEP11908A/xx unknown
- 2000-02-08 SI SI200030968T patent/SI1150970T1/sl unknown
- 2000-02-08 DE DE60036081T patent/DE60036081T2/de not_active Expired - Lifetime
- 2000-02-08 DK DK00903744T patent/DK1150970T3/da active
- 2000-02-08 JP JP2000598492A patent/JP4648544B2/ja not_active Expired - Fee Related
- 2000-02-08 TR TR2001/02331T patent/TR200102331T2/xx unknown
- 2000-02-08 KR KR1020017009983A patent/KR100611261B1/ko not_active IP Right Cessation
- 2000-02-08 ES ES00903744T patent/ES2291187T3/es not_active Expired - Lifetime
- 2000-02-08 CA CA002360894A patent/CA2360894C/en not_active Expired - Fee Related
- 2000-02-08 EP EP00903744A patent/EP1150970B1/fr not_active Expired - Lifetime
- 2000-02-08 AT AT00903744T patent/ATE370942T1/de not_active IP Right Cessation
- 2000-02-08 US US09/913,106 patent/US6642233B1/en not_active Expired - Fee Related
- 2000-02-09 AR ARP000100555A patent/AR028813A1/es active IP Right Grant
- 2000-02-09 TW TW089102106A patent/TWI254712B/zh active
- 2000-02-10 PE PE2000000102A patent/PE20001463A1/es not_active Application Discontinuation
- 2000-02-10 CO CO00008757A patent/CO4980896A1/es unknown
-
2001
- 2001-07-26 HR HR20010566A patent/HRP20010566A2/hr not_active Application Discontinuation
- 2001-08-08 NO NO20013878A patent/NO321149B1/no not_active IP Right Cessation
- 2001-08-08 BG BG105794A patent/BG65031B1/bg unknown
-
2002
- 2002-01-29 HK HK02100715A patent/HK1038927A1/xx not_active IP Right Cessation
-
2003
- 2003-09-16 US US10/663,124 patent/US6951940B2/en not_active Expired - Fee Related
-
2005
- 2005-04-21 NO NO20051958A patent/NO20051958L/no unknown
-
2007
- 2007-01-07 IL IL180579A patent/IL180579A0/en unknown
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