AR025569A1 - Pirazol [4,3-d] pirimidinas - Google Patents

Pirazol [4,3-d] pirimidinas

Info

Publication number
AR025569A1
AR025569A1 ARP000104648A ARP000104648A AR025569A1 AR 025569 A1 AR025569 A1 AR 025569A1 AR P000104648 A ARP000104648 A AR P000104648A AR P000104648 A ARP000104648 A AR P000104648A AR 025569 A1 AR025569 A1 AR 025569A1
Authority
AR
Argentina
Prior art keywords
pyrimidins
pirazol
treatment
pyrimidines
pyrazole
Prior art date
Application number
ARP000104648A
Other languages
English (en)
Spanish (es)
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of AR025569A1 publication Critical patent/AR025569A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure

Landscapes

  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Gynecology & Obstetrics (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
ARP000104648A 1999-09-06 2000-09-06 Pirazol [4,3-d] pirimidinas AR025569A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19942474A DE19942474A1 (de) 1999-09-06 1999-09-06 Pyrazolo[4,3-d]pyrimidine

Publications (1)

Publication Number Publication Date
AR025569A1 true AR025569A1 (es) 2002-12-04

Family

ID=7920966

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP000104648A AR025569A1 (es) 1999-09-06 2000-09-06 Pirazol [4,3-d] pirimidinas

Country Status (23)

Country Link
US (1) US6777419B1 (cs)
EP (1) EP1210349B1 (cs)
JP (1) JP4975921B2 (cs)
KR (1) KR20020025253A (cs)
CN (1) CN1145627C (cs)
AR (1) AR025569A1 (cs)
AT (1) ATE231866T1 (cs)
AU (1) AU773878B2 (cs)
BR (1) BR0013781A (cs)
CA (1) CA2384037C (cs)
CZ (1) CZ294587B6 (cs)
DE (2) DE19942474A1 (cs)
DK (1) DK1210349T3 (cs)
ES (1) ES2189766T3 (cs)
HU (1) HUP0202624A3 (cs)
MX (1) MXPA02002383A (cs)
NO (1) NO20021083L (cs)
PL (1) PL353366A1 (cs)
PT (1) PT1210349E (cs)
RU (1) RU2249594C2 (cs)
SK (1) SK3132002A3 (cs)
WO (1) WO2001018004A2 (cs)
ZA (1) ZA200202653B (cs)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10031584A1 (de) 2000-06-29 2002-01-10 Merck Patent Gmbh 5-Aminoalkyl-pyrazolo[4,3-d]pyrimidine
DE10058662A1 (de) * 2000-11-25 2002-05-29 Merck Patent Gmbh Verwendung von Pyrazolo[4,3-d]pyrimidinen
AU2002229573A1 (en) * 2000-12-19 2002-07-01 Merck Patent Gmbh Pharmaceutical formulation containing pyrazolo(4,3-D)pyrimidines and antithrombotic agents, calcium-antagonists, prostaglandins or prostaglandin derivatives
DE10103647A1 (de) 2001-01-27 2002-08-01 Merck Patent Gmbh Verfahren zur Herstellung eines Pyrazolo (4,3-d) pyrimidinderivates
DE10148883A1 (de) 2001-10-04 2003-04-10 Merck Patent Gmbh Pyrimidinderivate
MXPA05011643A (es) 2003-04-29 2005-12-15 Pfizer Ltd 5,7-diaminopirazolo[4,3-d]pirimidinas en el tratamiento de hipertension.
US7572799B2 (en) * 2003-11-24 2009-08-11 Pfizer Inc Pyrazolo[4,3-d]pyrimidines as Phosphodiesterase Inhibitors
GB0327323D0 (en) * 2003-11-24 2003-12-31 Pfizer Ltd Novel pharmaceuticals
BRPI0509731A (pt) * 2004-04-07 2007-09-25 Pfizer pirazol[4,3-d]pirimidinas
US8227475B2 (en) 2005-05-12 2012-07-24 Pfizer Inc. Anhydrous crystalline forms of N-[1-(2-ethoxyethyl)-5-(N-ethyl-N-methylamino)-7-(4-methylpyridin-2-yl-amino)-1H-pyrazolo[4,3-d]pyrimidine-3-carbonyl]methanesulfonamide
NL2000291C2 (nl) 2005-11-10 2009-02-17 Pfizer Prod Inc 1-(1-(2-ethoxyethyl)-3-ethyl-7-(4-methylpyridin-2-ylamino)-1H- pyrazool(4,3-d)pyrimidine-5-yl)piperidine-4-carbonzuur en zouten daarvan.
MX363696B (es) * 2011-04-21 2019-03-28 Origenis Gmbh Pirazolo[4,3-d]pirimidinas utiles como inhibidores de cinasas.
CZ308056B6 (cs) * 2015-07-20 2019-11-27 Ustav Experimentalni Botaniky Av Cr V V I 5-Substituované-7-[4-(substituované)benzyl]amino-3-isopropylpyrazolo[4,3-d]pyrimidiny, jejich použití jako antirevmatika, a farmaceutické přípravky
US10034861B2 (en) 2016-07-04 2018-07-31 H. Lundbeck A/S 1H-pyrazolo[4,3-b]pyridines as PDE1 inhibitors
AR113926A1 (es) 2017-12-14 2020-07-01 H Lundbeck As Derivados de 1h-pirazolo[4,3-b]piridinas
US11634416B2 (en) * 2017-12-14 2023-04-25 H. Lundbeck A/S Combination treatments comprising administration of 1H-pyrazolo[4,3-b]pyridines
US10766893B2 (en) * 2017-12-20 2020-09-08 H. Lundbeck A/S 1H-pyrazolo[4,3-b]pyridines as PDE1 inhibitors
CN111511742B (zh) 2017-12-20 2023-10-27 H.隆德贝克有限公司 作为PDE1抑制剂的吡唑并[4,3-b]吡啶和咪唑并[1,5-a]嘧啶

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5256650A (en) * 1989-03-29 1993-10-26 Merrell Dow Pharmaceuticals Inc. Selective adenosine receptor agents
GB9114760D0 (en) * 1991-07-09 1991-08-28 Pfizer Ltd Therapeutic agents
DE19644228A1 (de) * 1996-10-24 1998-04-30 Merck Patent Gmbh Thienopyrimidine
ID22834A (id) * 1997-04-25 1999-12-09 Pfizer Pirazolopimidinona untuk kelainan seksual
DE19752952A1 (de) * 1997-11-28 1999-06-02 Merck Patent Gmbh Thienopyrimidine
DE10031584A1 (de) * 2000-06-29 2002-01-10 Merck Patent Gmbh 5-Aminoalkyl-pyrazolo[4,3-d]pyrimidine
DE10058662A1 (de) * 2000-11-25 2002-05-29 Merck Patent Gmbh Verwendung von Pyrazolo[4,3-d]pyrimidinen
DE10060388A1 (de) * 2000-12-05 2002-06-06 Merck Patent Gmbh Verwendung von Pyrazolo [4,3-d]pyrimidinen
DE10103647A1 (de) * 2001-01-27 2002-08-01 Merck Patent Gmbh Verfahren zur Herstellung eines Pyrazolo (4,3-d) pyrimidinderivates

Also Published As

Publication number Publication date
DE19942474A1 (de) 2001-03-15
US6777419B1 (en) 2004-08-17
EP1210349B1 (de) 2003-01-29
CA2384037A1 (en) 2001-03-15
HUP0202624A3 (en) 2004-11-29
WO2001018004A3 (de) 2001-08-09
BR0013781A (pt) 2002-05-14
RU2249594C2 (ru) 2005-04-10
DK1210349T3 (da) 2003-05-19
CZ2002736A3 (cs) 2002-05-15
WO2001018004A2 (de) 2001-03-15
ES2189766T3 (es) 2003-07-16
ZA200202653B (en) 2003-09-23
HUP0202624A2 (hu) 2002-12-28
JP2003508534A (ja) 2003-03-04
NO20021083D0 (no) 2002-03-05
NO20021083L (no) 2002-03-05
MXPA02002383A (es) 2002-09-02
CN1145627C (zh) 2004-04-14
AU773878B2 (en) 2004-06-10
ATE231866T1 (de) 2003-02-15
KR20020025253A (ko) 2002-04-03
DE50001191D1 (de) 2003-03-06
AU7279300A (en) 2001-04-10
CN1377357A (zh) 2002-10-30
SK3132002A3 (en) 2002-07-02
PL353366A1 (en) 2003-11-17
CA2384037C (en) 2009-10-13
PT1210349E (pt) 2003-06-30
EP1210349A2 (de) 2002-06-05
JP4975921B2 (ja) 2012-07-11
CZ294587B6 (cs) 2005-02-16

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