AR024998A1 - Nuevos retinoides para el tratamiento del enfisema - Google Patents
Nuevos retinoides para el tratamiento del enfisemaInfo
- Publication number
- AR024998A1 AR024998A1 ARP000103950A ARP000103950A AR024998A1 AR 024998 A1 AR024998 A1 AR 024998A1 AR P000103950 A ARP000103950 A AR P000103950A AR P000103950 A ARP000103950 A AR P000103950A AR 024998 A1 AR024998 A1 AR 024998A1
- Authority
- AR
- Argentina
- Prior art keywords
- disease
- treatment
- new
- new retinoids
- retinoids
- Prior art date
Links
- 201000010099 disease Diseases 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title 1
- 239000000556 agonist Substances 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 150000004492 retinoid derivatives Chemical class 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 229940124597 therapeutic agent Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/07—Retinol compounds, e.g. vitamin A
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/79—Acids; Esters
- C07D213/80—Acids; Esters in position 3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/57—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of rings other than six-membered aromatic rings
- C07C233/63—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of rings other than six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C61/00—Compounds having carboxyl groups bound to carbon atoms of rings other than six-membered aromatic rings
- C07C61/16—Unsaturated compounds
- C07C61/28—Unsaturated compounds polycyclic
- C07C61/29—Unsaturated compounds polycyclic having a carboxyl group bound to a condensed ring system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C63/00—Compounds having carboxyl groups bound to a carbon atoms of six-membered aromatic rings
- C07C63/66—Polycyclic acids with unsaturation outside the aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/74—Esters of carboxylic acids having an esterified carboxyl group bound to a carbon atom of a ring other than a six-membered aromatic ring
- C07C69/753—Esters of carboxylic acids having an esterified carboxyl group bound to a carbon atom of a ring other than a six-membered aromatic ring of polycyclic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/04—One of the condensed rings being a six-membered aromatic ring
- C07C2602/08—One of the condensed rings being a six-membered aromatic ring the other ring being five-membered, e.g. indane
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Dermatology (AREA)
- Epidemiology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP99115223 | 1999-08-02 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR024998A1 true AR024998A1 (es) | 2002-11-06 |
Family
ID=8238709
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP000103950A AR024998A1 (es) | 1999-08-02 | 2000-07-31 | Nuevos retinoides para el tratamiento del enfisema |
Country Status (18)
| Country | Link |
|---|---|
| US (3) | US6528677B1 (enExample) |
| EP (1) | EP1206436B1 (enExample) |
| JP (1) | JP3961827B2 (enExample) |
| KR (1) | KR100466730B1 (enExample) |
| CN (1) | CN1166618C (enExample) |
| AR (1) | AR024998A1 (enExample) |
| AT (1) | ATE279386T1 (enExample) |
| AU (1) | AU772551B2 (enExample) |
| BR (1) | BR0012951A (enExample) |
| CA (1) | CA2386793C (enExample) |
| DE (1) | DE60014928T2 (enExample) |
| DK (1) | DK1206436T3 (enExample) |
| ES (1) | ES2228587T3 (enExample) |
| MX (1) | MXPA02000828A (enExample) |
| PT (1) | PT1206436E (enExample) |
| TR (1) | TR200200263T2 (enExample) |
| WO (1) | WO2001009076A2 (enExample) |
| ZA (1) | ZA200200516B (enExample) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JO2178B1 (en) * | 1999-10-19 | 2003-04-23 | اف . هوفمان لاروش ايه جي | Treatment of invasive diseases, using selected anti-PAR materials |
| US20060189893A1 (en) * | 2005-01-06 | 2006-08-24 | Diamics, Inc. | Systems and methods for detecting abnormal cells |
| US20060161076A1 (en) * | 2005-01-06 | 2006-07-20 | Diamics, Inc. | Systems and methods for collection of cell clusters |
| US7914437B2 (en) * | 2005-02-04 | 2011-03-29 | Ams Research Corporation | Transobturator methods for installing sling to treat incontinence, and related devices |
| US8415390B2 (en) | 2008-05-30 | 2013-04-09 | Microdose Therapeutx, Inc. | Methods and compositions for administration of oxybutynin |
| US9119777B2 (en) | 2008-05-30 | 2015-09-01 | Microdose Therapeutx, Inc. | Methods and compositions for administration of oxybutynin |
| HRP20160430T1 (hr) | 2007-09-10 | 2016-05-20 | Boston Biomedical, Inc. | Nova grupa inhibitora stat3 puta i inhibitora puta matičnih stanica karcinoma |
| US9730909B2 (en) | 2010-03-19 | 2017-08-15 | Boston Biomedical, Inc | Methods for targeting cancer stem cells |
| US8772273B2 (en) * | 2011-10-04 | 2014-07-08 | Quretino Therapeutics, Inc. | Formulations and uses of retinoic acid receptor selective agonists |
| EP2768307B1 (en) * | 2011-10-19 | 2020-03-18 | Bikam Pharmaceuticals, Inc. | Opsin-binding ligands, compositions and methods of use |
| KR20150139955A (ko) | 2013-04-09 | 2015-12-14 | 보스톤 바이오메디칼, 인크. | 암 치료에 사용하기 위한 2-아세틸나프토[2,3-b]푸란-4,9-디온 |
| RS59007B1 (sr) | 2014-02-03 | 2019-08-30 | Vitae Pharmaceuticals Llc | Dihidropirolopiridinski inhibitori ror-gama |
| EA031967B1 (ru) | 2014-10-14 | 2019-03-29 | Вайтаи Фармасьютиклз, Инк. | ДИГИДРОПИРРОЛОПИРИДИНОВЫЕ ИНГИБИТОРЫ ROR-γ |
| US9663515B2 (en) | 2014-11-05 | 2017-05-30 | Vitae Pharmaceuticals, Inc. | Dihydropyrrolopyridine inhibitors of ROR-gamma |
| WO2017024018A1 (en) | 2015-08-05 | 2017-02-09 | Vitae Pharmaceuticals, Inc. | Modulators of ror-gamma |
| KR20180086221A (ko) | 2015-11-20 | 2018-07-30 | 비타이 파마슈티컬즈, 인코포레이티드 | Ror-감마의 조절물질 |
| TW202220968A (zh) | 2016-01-29 | 2022-06-01 | 美商維它藥物有限責任公司 | ＲＯＲ－γ調節劑 |
| US11299469B2 (en) | 2016-11-29 | 2022-04-12 | Sumitomo Dainippon Pharma Oncology, Inc. | Naphthofuran derivatives, preparation, and methods of use thereof |
| US10646464B2 (en) | 2017-05-17 | 2020-05-12 | Boston Biomedical, Inc. | Methods for treating cancer |
| MA49685A (fr) | 2017-07-24 | 2021-04-14 | Vitae Pharmaceuticals Llc | INHIBITEURS DE ROR gamma |
| WO2019018975A1 (en) | 2017-07-24 | 2019-01-31 | Vitae Pharmaceuticals, Inc. | INHIBITORS OF ROR GAMMA |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| LU87821A1 (fr) * | 1990-10-12 | 1992-05-25 | Cird Galderma | Composes bi-aromatiques,et leur utilisation en medecine humaine et veterinaire et en cosmetique |
| US5958954A (en) * | 1995-09-01 | 1999-09-28 | Allergan Sales, Inc. | Synthesis and use of retinoid compounds having negative hormone and/or antagonist activities |
-
2000
- 2000-07-25 MX MXPA02000828A patent/MXPA02000828A/es active IP Right Grant
- 2000-07-25 JP JP2001514280A patent/JP3961827B2/ja not_active Expired - Fee Related
- 2000-07-25 ES ES00951439T patent/ES2228587T3/es not_active Expired - Lifetime
- 2000-07-25 DK DK00951439T patent/DK1206436T3/da active
- 2000-07-25 BR BR0012951-8A patent/BR0012951A/pt not_active Application Discontinuation
- 2000-07-25 EP EP00951439A patent/EP1206436B1/en not_active Expired - Lifetime
- 2000-07-25 PT PT00951439T patent/PT1206436E/pt unknown
- 2000-07-25 CA CA002386793A patent/CA2386793C/en not_active Expired - Fee Related
- 2000-07-25 CN CNB008112568A patent/CN1166618C/zh not_active Expired - Fee Related
- 2000-07-25 WO PCT/EP2000/007091 patent/WO2001009076A2/en not_active Ceased
- 2000-07-25 TR TR2002/00263T patent/TR200200263T2/xx unknown
- 2000-07-25 AU AU64373/00A patent/AU772551B2/en not_active Ceased
- 2000-07-25 AT AT00951439T patent/ATE279386T1/de not_active IP Right Cessation
- 2000-07-25 DE DE60014928T patent/DE60014928T2/de not_active Expired - Fee Related
- 2000-07-25 KR KR10-2002-7001433A patent/KR100466730B1/ko not_active Expired - Fee Related
- 2000-07-26 US US09/625,806 patent/US6528677B1/en not_active Expired - Fee Related
- 2000-07-31 AR ARP000103950A patent/AR024998A1/es unknown
-
2002
- 2002-01-21 ZA ZA200200516A patent/ZA200200516B/en unknown
- 2002-12-19 US US10/323,306 patent/US6828337B2/en not_active Expired - Fee Related
-
2004
- 2004-11-02 US US10/979,355 patent/US20050113447A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| BR0012951A (pt) | 2002-04-30 |
| DE60014928T2 (de) | 2006-03-09 |
| KR20020030089A (ko) | 2002-04-22 |
| KR100466730B1 (ko) | 2005-01-24 |
| CN1166618C (zh) | 2004-09-15 |
| PT1206436E (pt) | 2004-12-31 |
| EP1206436B1 (en) | 2004-10-13 |
| WO2001009076A2 (en) | 2001-02-08 |
| US20030176726A1 (en) | 2003-09-18 |
| MXPA02000828A (es) | 2002-07-30 |
| AU6437300A (en) | 2001-02-19 |
| US6528677B1 (en) | 2003-03-04 |
| US6828337B2 (en) | 2004-12-07 |
| DK1206436T3 (da) | 2005-02-14 |
| EP1206436A2 (en) | 2002-05-22 |
| CA2386793A1 (en) | 2001-02-08 |
| JP3961827B2 (ja) | 2007-08-22 |
| CA2386793C (en) | 2006-03-28 |
| JP2003526626A (ja) | 2003-09-09 |
| TR200200263T2 (tr) | 2004-12-21 |
| CN1368946A (zh) | 2002-09-11 |
| ES2228587T3 (es) | 2005-04-16 |
| US20050113447A1 (en) | 2005-05-26 |
| DE60014928D1 (de) | 2004-11-18 |
| WO2001009076A3 (en) | 2001-07-19 |
| ZA200200516B (en) | 2003-06-25 |
| ATE279386T1 (de) | 2004-10-15 |
| AU772551B2 (en) | 2004-04-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FB | Suspension of granting procedure |