PT1206436E - Retinoides para o tratamento de enfisema - Google Patents
Retinoides para o tratamento de enfisemaInfo
- Publication number
- PT1206436E PT1206436E PT00951439T PT00951439T PT1206436E PT 1206436 E PT1206436 E PT 1206436E PT 00951439 T PT00951439 T PT 00951439T PT 00951439 T PT00951439 T PT 00951439T PT 1206436 E PT1206436 E PT 1206436E
- Authority
- PT
- Portugal
- Prior art keywords
- enfisema
- retinoids
- treatment
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/07—Retinol compounds, e.g. vitamin A
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/79—Acids; Esters
- C07D213/80—Acids; Esters in position 3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/57—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of rings other than six-membered aromatic rings
- C07C233/63—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of rings other than six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C61/00—Compounds having carboxyl groups bound to carbon atoms of rings other than six-membered aromatic rings
- C07C61/16—Unsaturated compounds
- C07C61/28—Unsaturated compounds polycyclic
- C07C61/29—Unsaturated compounds polycyclic having a carboxyl group bound to a condensed ring system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C63/00—Compounds having carboxyl groups bound to a carbon atoms of six-membered aromatic rings
- C07C63/66—Polycyclic acids with unsaturation outside the aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/74—Esters of carboxylic acids having an esterified carboxyl group bound to a carbon atom of a ring other than a six-membered aromatic ring
- C07C69/753—Esters of carboxylic acids having an esterified carboxyl group bound to a carbon atom of a ring other than a six-membered aromatic ring of polycyclic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/04—One of the condensed rings being a six-membered aromatic ring
- C07C2602/08—One of the condensed rings being a six-membered aromatic ring the other ring being five-membered, e.g. indane
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pulmonology (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP99115223 | 1999-08-02 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT1206436E true PT1206436E (pt) | 2004-12-31 |
Family
ID=8238709
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT00951439T PT1206436E (pt) | 1999-08-02 | 2000-07-25 | Retinoides para o tratamento de enfisema |
Country Status (18)
| Country | Link |
|---|---|
| US (3) | US6528677B1 (enExample) |
| EP (1) | EP1206436B1 (enExample) |
| JP (1) | JP3961827B2 (enExample) |
| KR (1) | KR100466730B1 (enExample) |
| CN (1) | CN1166618C (enExample) |
| AR (1) | AR024998A1 (enExample) |
| AT (1) | ATE279386T1 (enExample) |
| AU (1) | AU772551B2 (enExample) |
| BR (1) | BR0012951A (enExample) |
| CA (1) | CA2386793C (enExample) |
| DE (1) | DE60014928T2 (enExample) |
| DK (1) | DK1206436T3 (enExample) |
| ES (1) | ES2228587T3 (enExample) |
| MX (1) | MXPA02000828A (enExample) |
| PT (1) | PT1206436E (enExample) |
| TR (1) | TR200200263T2 (enExample) |
| WO (1) | WO2001009076A2 (enExample) |
| ZA (1) | ZA200200516B (enExample) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JO2178B1 (en) * | 1999-10-19 | 2003-04-23 | اف . هوفمان لاروش ايه جي | Treatment of emphysema using rar selective retinoid antagonists |
| US20060161076A1 (en) * | 2005-01-06 | 2006-07-20 | Diamics, Inc. | Systems and methods for collection of cell clusters |
| US20060189893A1 (en) * | 2005-01-06 | 2006-08-24 | Diamics, Inc. | Systems and methods for detecting abnormal cells |
| US7914437B2 (en) * | 2005-02-04 | 2011-03-29 | Ams Research Corporation | Transobturator methods for installing sling to treat incontinence, and related devices |
| US8415390B2 (en) | 2008-05-30 | 2013-04-09 | Microdose Therapeutx, Inc. | Methods and compositions for administration of oxybutynin |
| US9119777B2 (en) | 2008-05-30 | 2015-09-01 | Microdose Therapeutx, Inc. | Methods and compositions for administration of oxybutynin |
| EP2190429B1 (en) | 2007-09-10 | 2016-04-20 | Boston Biomedical, Inc. | A novel group of stat3 pathway inhibitors and cancer stem cell pathway inhibitors |
| DK2547205T3 (da) | 2010-03-19 | 2024-05-27 | 1Globe Biomedical Co Ltd | Hidtil ukendte fremgangsmåder til målretning mod cancerstamceller |
| US8772273B2 (en) * | 2011-10-04 | 2014-07-08 | Quretino Therapeutics, Inc. | Formulations and uses of retinoic acid receptor selective agonists |
| CA2856703A1 (en) | 2011-10-19 | 2013-04-25 | Bikam Pharmaceuticals, Inc. | Opsin-binding ligands, compositions and methods of use |
| US20160030384A1 (en) | 2013-04-09 | 2016-02-04 | Boston Biomedical, Inc. | 2-acetylnaphtho[2,3-b]furan -4,9-dione for use on treating cancer |
| DK3102576T3 (da) | 2014-02-03 | 2019-07-22 | Vitae Pharmaceuticals Llc | Dihydropyrrolopyridininhibitorer af ror-gamma |
| SI3207043T1 (sl) | 2014-10-14 | 2019-04-30 | Vitae Pharmaceuticals, Inc. | Dihidropirolopiridinovi inhibitorji za ROR-gama |
| US9663515B2 (en) | 2014-11-05 | 2017-05-30 | Vitae Pharmaceuticals, Inc. | Dihydropyrrolopyridine inhibitors of ROR-gamma |
| EP3331876B1 (en) | 2015-08-05 | 2020-10-07 | Vitae Pharmaceuticals, LLC | Modulators of ror-gamma |
| EP3868750A1 (en) | 2015-11-20 | 2021-08-25 | Vitae Pharmaceuticals, LLC | Modulators of ror-gamma |
| TWI757266B (zh) | 2016-01-29 | 2022-03-11 | 美商維它藥物有限責任公司 | ＲＯＲ－γ調節劑 |
| CA3045306A1 (en) | 2016-11-29 | 2018-06-07 | Boston Biomedical, Inc. | Naphthofuran derivatives, preparation, and methods of use thereof |
| JP2020520923A (ja) | 2017-05-17 | 2020-07-16 | ボストン バイオメディカル， インコーポレイテッド | がんを処置するための方法 |
| WO2019018975A1 (en) | 2017-07-24 | 2019-01-31 | Vitae Pharmaceuticals, Inc. | INHIBITORS OF ROR GAMMA |
| CN115716826A (zh) | 2017-07-24 | 2023-02-28 | 生命医药有限责任公司 | RORγ的抑制剂 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| LU87821A1 (fr) * | 1990-10-12 | 1992-05-25 | Cird Galderma | Composes bi-aromatiques,et leur utilisation en medecine humaine et veterinaire et en cosmetique |
| US5958954A (en) * | 1995-09-01 | 1999-09-28 | Allergan Sales, Inc. | Synthesis and use of retinoid compounds having negative hormone and/or antagonist activities |
-
2000
- 2000-07-25 PT PT00951439T patent/PT1206436E/pt unknown
- 2000-07-25 AT AT00951439T patent/ATE279386T1/de not_active IP Right Cessation
- 2000-07-25 MX MXPA02000828A patent/MXPA02000828A/es active IP Right Grant
- 2000-07-25 ES ES00951439T patent/ES2228587T3/es not_active Expired - Lifetime
- 2000-07-25 TR TR2002/00263T patent/TR200200263T2/xx unknown
- 2000-07-25 DE DE60014928T patent/DE60014928T2/de not_active Expired - Fee Related
- 2000-07-25 KR KR10-2002-7001433A patent/KR100466730B1/ko not_active Expired - Fee Related
- 2000-07-25 WO PCT/EP2000/007091 patent/WO2001009076A2/en not_active Ceased
- 2000-07-25 BR BR0012951-8A patent/BR0012951A/pt not_active Application Discontinuation
- 2000-07-25 DK DK00951439T patent/DK1206436T3/da active
- 2000-07-25 EP EP00951439A patent/EP1206436B1/en not_active Expired - Lifetime
- 2000-07-25 JP JP2001514280A patent/JP3961827B2/ja not_active Expired - Fee Related
- 2000-07-25 CA CA002386793A patent/CA2386793C/en not_active Expired - Fee Related
- 2000-07-25 AU AU64373/00A patent/AU772551B2/en not_active Ceased
- 2000-07-25 CN CNB008112568A patent/CN1166618C/zh not_active Expired - Fee Related
- 2000-07-26 US US09/625,806 patent/US6528677B1/en not_active Expired - Fee Related
- 2000-07-31 AR ARP000103950A patent/AR024998A1/es unknown
-
2002
- 2002-01-21 ZA ZA200200516A patent/ZA200200516B/en unknown
- 2002-12-19 US US10/323,306 patent/US6828337B2/en not_active Expired - Fee Related
-
2004
- 2004-11-02 US US10/979,355 patent/US20050113447A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| ZA200200516B (en) | 2003-06-25 |
| AR024998A1 (es) | 2002-11-06 |
| US20030176726A1 (en) | 2003-09-18 |
| WO2001009076A3 (en) | 2001-07-19 |
| CA2386793C (en) | 2006-03-28 |
| TR200200263T2 (tr) | 2004-12-21 |
| US6528677B1 (en) | 2003-03-04 |
| US20050113447A1 (en) | 2005-05-26 |
| ES2228587T3 (es) | 2005-04-16 |
| JP2003526626A (ja) | 2003-09-09 |
| AU772551B2 (en) | 2004-04-29 |
| KR100466730B1 (ko) | 2005-01-24 |
| ATE279386T1 (de) | 2004-10-15 |
| EP1206436B1 (en) | 2004-10-13 |
| DK1206436T3 (da) | 2005-02-14 |
| MXPA02000828A (es) | 2002-07-30 |
| DE60014928D1 (de) | 2004-11-18 |
| KR20020030089A (ko) | 2002-04-22 |
| EP1206436A2 (en) | 2002-05-22 |
| WO2001009076A2 (en) | 2001-02-08 |
| CN1166618C (zh) | 2004-09-15 |
| CA2386793A1 (en) | 2001-02-08 |
| BR0012951A (pt) | 2002-04-30 |
| DE60014928T2 (de) | 2006-03-09 |
| US6828337B2 (en) | 2004-12-07 |
| AU6437300A (en) | 2001-02-19 |
| JP3961827B2 (ja) | 2007-08-22 |
| CN1368946A (zh) | 2002-09-11 |
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