AR024350A1 - Antagonistas de los receptores de il-8 - Google Patents
Antagonistas de los receptores de il-8Info
- Publication number
- AR024350A1 AR024350A1 ARP000102922A ARP000102922A AR024350A1 AR 024350 A1 AR024350 A1 AR 024350A1 AR P000102922 A ARP000102922 A AR P000102922A AR P000102922 A ARP000102922 A AR P000102922A AR 024350 A1 AR024350 A1 AR 024350A1
- Authority
- AR
- Argentina
- Prior art keywords
- antagonists
- receivers
- chemokine
- interleukin
- refers
- Prior art date
Links
- 108090001007 Interleukin-8 Proteins 0.000 title abstract 3
- 239000005557 antagonist Substances 0.000 title 1
- 102000004890 Interleukin-8 Human genes 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 230000001404 mediated effect Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/428—Thiazoles condensed with carbocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A61P33/06—Antimalarials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Virology (AREA)
- Epidemiology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Tropical Medicine & Parasitology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Hematology (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Immunology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Diabetes (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
La presente se refiere a nuevos compuestos de formula (1), y composiciones farmacéuticas de los mismos, así como a métodos de tratamiento de estados deenfermedad mediados por la quimiocina Interleucina-8 (IL-8).
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US14002499P | 1999-06-16 | 1999-06-16 |
Publications (1)
Publication Number | Publication Date |
---|---|
AR024350A1 true AR024350A1 (es) | 2002-10-02 |
Family
ID=22489379
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP000102922A AR024350A1 (es) | 1999-06-16 | 2000-06-14 | Antagonistas de los receptores de il-8 |
Country Status (19)
Country | Link |
---|---|
EP (1) | EP1185265A4 (es) |
JP (1) | JP2003501463A (es) |
KR (1) | KR20020015347A (es) |
CN (1) | CN1356899A (es) |
AR (1) | AR024350A1 (es) |
AU (1) | AU766235B2 (es) |
BR (1) | BR0011122A (es) |
CA (1) | CA2377386A1 (es) |
CO (1) | CO5190696A1 (es) |
CZ (1) | CZ20014472A3 (es) |
HU (1) | HUP0201582A3 (es) |
IL (1) | IL145762A0 (es) |
MX (1) | MXPA01013005A (es) |
NO (1) | NO20016052L (es) |
NZ (1) | NZ514696A (es) |
PL (1) | PL352213A1 (es) |
TR (1) | TR200103638T2 (es) |
WO (1) | WO2000076501A1 (es) |
ZA (1) | ZA200109480B (es) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE60326080D1 (en) | 2002-10-09 | 2009-03-19 | Schering Corp | Thiadiazoldioxide und thiadiazoloxide als cxc- und cc-chemokinrezeptor liganden |
DE10334309A1 (de) * | 2003-07-28 | 2005-03-03 | Aventis Pharma Deutschland Gmbh | Substituierte Thiazol-Benzoisothiazoldioxidderivate, Verfahren zu deren Herstellung und deren Verwendung |
US7094794B2 (en) | 2003-07-28 | 2006-08-22 | Sanofi-Aventis Deutschland Gmbh | Substituted thiazole-benzoisothiazole dioxide derivatives, process for their preparation and their use |
CN1852905A (zh) | 2003-08-21 | 2006-10-25 | Osi制药公司 | 具有n-取代的苯并咪唑基的c-kit抑制剂 |
KR20060115346A (ko) | 2003-08-21 | 2006-11-08 | 오에스아이 파마슈티컬스, 인코포레이티드 | N―치환된 피라졸릴-아미딜-벤즈이미다졸릴 c―kit억제제 |
US7442709B2 (en) | 2003-08-21 | 2008-10-28 | Osi Pharmaceuticals, Inc. | N3-substituted imidazopyridine c-Kit inhibitors |
TW200528450A (en) | 2003-12-19 | 2005-09-01 | Schering Corp | Thiadiazoles as cxc-and cc-chemokine receptor ligands |
AU2005299771A1 (en) | 2004-10-21 | 2006-05-04 | High Point Pharmaceuticals, Llc | Bissulfonamide compounds as agonists of GalR1, compositions, and methods of use |
CN101193867A (zh) | 2004-12-01 | 2008-06-04 | Osi医药有限公司 | N取代的苯并咪唑基c-Kit抑制剂和苯并咪唑组合库 |
EA201290073A1 (ru) | 2009-08-24 | 2013-01-30 | Эсэпиен Фармасьютикалз, Инк. | Соединения мочевины, содержащие 5,6-бициклический гетероарил, как ингибиторы киназ |
EP2377850A1 (en) | 2010-03-30 | 2011-10-19 | Pharmeste S.r.l. | TRPV1 vanilloid receptor antagonists with a bicyclic portion |
CN102060780B (zh) * | 2010-12-27 | 2014-11-05 | 雅本化学股份有限公司 | 2-(n-取代)-氨基苯并咪唑衍生物的制备方法 |
CN111116502A (zh) * | 2018-10-30 | 2020-05-08 | 中国石油化工股份有限公司 | 一步法合成苯骈三氮唑的方法 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ZA921120B (en) * | 1991-02-19 | 1993-01-27 | Smithkline Beecham Corp | Cytokine inhibitors |
BR9807083A (pt) * | 1997-01-23 | 2000-04-18 | Smithkline Beckman Corp | Antagonistas ao receptor de il-8 |
-
2000
- 2000-06-13 CO CO00043846A patent/CO5190696A1/es not_active Application Discontinuation
- 2000-06-14 AR ARP000102922A patent/AR024350A1/es not_active Application Discontinuation
- 2000-06-15 AU AU56161/00A patent/AU766235B2/en not_active Ceased
- 2000-06-15 EP EP00941455A patent/EP1185265A4/en not_active Withdrawn
- 2000-06-15 BR BR0011122-8A patent/BR0011122A/pt not_active IP Right Cessation
- 2000-06-15 NZ NZ514696A patent/NZ514696A/xx unknown
- 2000-06-15 JP JP2001502834A patent/JP2003501463A/ja not_active Withdrawn
- 2000-06-15 CA CA002377386A patent/CA2377386A1/en not_active Abandoned
- 2000-06-15 KR KR1020017016144A patent/KR20020015347A/ko not_active Application Discontinuation
- 2000-06-15 WO PCT/US2000/016506 patent/WO2000076501A1/en not_active Application Discontinuation
- 2000-06-15 IL IL14576200A patent/IL145762A0/xx unknown
- 2000-06-15 PL PL00352213A patent/PL352213A1/xx not_active Application Discontinuation
- 2000-06-15 MX MXPA01013005A patent/MXPA01013005A/es unknown
- 2000-06-15 CN CN00809090A patent/CN1356899A/zh active Pending
- 2000-06-15 HU HU0201582A patent/HUP0201582A3/hu unknown
- 2000-06-15 TR TR2001/03638T patent/TR200103638T2/xx unknown
- 2000-06-15 CZ CZ20014472A patent/CZ20014472A3/cs unknown
- 2000-11-16 ZA ZA200109480A patent/ZA200109480B/en unknown
-
2001
- 2001-12-11 NO NO20016052A patent/NO20016052L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
CO5190696A1 (es) | 2002-08-29 |
MXPA01013005A (es) | 2002-07-02 |
NO20016052D0 (no) | 2001-12-11 |
EP1185265A1 (en) | 2002-03-13 |
PL352213A1 (en) | 2003-08-11 |
AU5616100A (en) | 2001-01-02 |
NO20016052L (no) | 2001-12-11 |
ZA200109480B (en) | 2002-11-18 |
EP1185265A4 (en) | 2004-02-04 |
WO2000076501A1 (en) | 2000-12-21 |
IL145762A0 (en) | 2002-07-25 |
CA2377386A1 (en) | 2000-12-21 |
BR0011122A (pt) | 2002-02-26 |
AU766235B2 (en) | 2003-10-09 |
CZ20014472A3 (cs) | 2002-06-12 |
KR20020015347A (ko) | 2002-02-27 |
CN1356899A (zh) | 2002-07-03 |
JP2003501463A (ja) | 2003-01-14 |
HUP0201582A2 (hu) | 2002-12-28 |
TR200103638T2 (tr) | 2002-04-22 |
NZ514696A (en) | 2004-03-26 |
HUP0201582A3 (en) | 2003-02-28 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
BR0313109A (pt) | Ciclobuteno-1,2-dionas 3,4-dissubstituìdas como ligandos de receptor de quimiocina de cxc | |
AR024350A1 (es) | Antagonistas de los receptores de il-8 | |
EA200500342A1 (ru) | Гетероциклические замещённые пиперазины для лечения шизофрении | |
GT200100160A (es) | Derivados 4-fenil-piridina. | |
EA200300717A1 (ru) | Гетероциклилиндазольные и -азаиндазольные соединения в качестве 5-гидрокситриптамин-6-лигандов | |
CY1106514T1 (el) | Ανταγωνιστες υποδοχεων il-8 | |
BR9916159A (pt) | Sulfonamidas de hidróxi-difenil-uréia comoantagonistas dos receptores de il-8 | |
BRPI0514738A (pt) | derivados de amida de 3-fenil-diidropirimido[4,5-d]pirimidinonas, sua fabricação e aplicação como agentes farmacêuticos | |
EA200200194A1 (ru) | Антагонисты хемокинного рецептора и способы их применения | |
TR199901710T2 (xx) | IL-8 resept�r antagonistleri. | |
BRPI0415773A (pt) | derivados de indolinona e sua aplicação no tratamento de estados de doença tais como cáncer | |
DE60230722D1 (de) | Il-8-rezeptor-antagonisten | |
ATE365730T1 (de) | Neuartige verbindungen | |
EA200200933A1 (ru) | Антагонисты рецептора il-8 | |
BR0111279A (pt) | Derivados da ciclohexilamina como antagonistas para o receptor do nmda seletivo ao subtipo | |
WO2005000231A3 (en) | Il-8 receptor antagonists | |
AP1548A (en) | Il-8 Receptor Antagonists. | |
WO2001068569A3 (en) | Il-8 receptor antagonists | |
TR199901761T2 (xx) | IL-8 resept�r antagonistleri. | |
AP2002002606A0 (en) | INTERLEUKIN 8 RECEPTOR ANTAGONISTS | |
MY143477A (en) | Il-8 receptor antagonists | |
ATE384066T1 (de) | Thieno-pyrrole verbindungen als antagonisten der gonadotropin-freisetzenden hormonrezeptoren | |
WO2004033436A8 (en) | Sulfonylbenzodiazepinone acetamides as bradykinin antagonists | |
BRPI0415767A (pt) | antagonistas de receptor de ccr-3 | |
WO2001068033A3 (en) | Il-8 receptor antagonists |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FA | Abandonment or withdrawal |