AR018505A1 - COMPOSICIoN FARMACÉUTICA ANTIHISTAMíNICA CON UN INHIBIDOR DE LA P-GLICOPROTEíNA Y EL USO DE DICHA COMPOSICIoN PARA LA FABRICACIoN DE MEDICAMENTOS PARA AUMENTAR LA BIODISPONIBILIDAD DE DICHO ANTIHISTAMíNICO. - Google Patents
COMPOSICIoN FARMACÉUTICA ANTIHISTAMíNICA CON UN INHIBIDOR DE LA P-GLICOPROTEíNA Y EL USO DE DICHA COMPOSICIoN PARA LA FABRICACIoN DE MEDICAMENTOS PARA AUMENTAR LA BIODISPONIBILIDAD DE DICHO ANTIHISTAMíNICO.Info
- Publication number
- AR018505A1 AR018505A1 ARP980104005A ARP980104005A AR018505A1 AR 018505 A1 AR018505 A1 AR 018505A1 AR P980104005 A ARP980104005 A AR P980104005A AR P980104005 A ARP980104005 A AR P980104005A AR 018505 A1 AR018505 A1 AR 018505A1
- Authority
- AR
- Argentina
- Prior art keywords
- antihistaminal
- glycoprotein
- antihistamine
- manufacture
- composition
- Prior art date
Links
- 102100033350 ATP-dependent translocase ABCB1 Human genes 0.000 title abstract 3
- 108010047230 Member 1 Subfamily B ATP Binding Cassette Transporter Proteins 0.000 title abstract 3
- 239000003814 drug Substances 0.000 title abstract 3
- 238000004519 manufacturing process Methods 0.000 title abstract 3
- 239000000203 mixture Substances 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 239000003112 inhibitor Substances 0.000 title 1
- GUGOEEXESWIERI-UHFFFAOYSA-N Terfenadine Chemical compound C1=CC(C(C)(C)C)=CC=C1C(O)CCCN1CCC(C(O)(C=2C=CC=CC=2)C=2C=CC=CC=2)CC1 GUGOEEXESWIERI-UHFFFAOYSA-N 0.000 abstract 6
- 230000001387 anti-histamine Effects 0.000 abstract 6
- 239000000739 antihistaminic agent Substances 0.000 abstract 6
- 229940049937 Pgp inhibitor Drugs 0.000 abstract 2
- 239000002748 glycoprotein P inhibitor Substances 0.000 abstract 2
- 230000002401 inhibitory effect Effects 0.000 abstract 2
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 1
- 206010020751 Hypersensitivity Diseases 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 230000003287 optical effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/74—Synthetic polymeric materials
- A61K31/745—Polymers of hydrocarbons
- A61K31/75—Polymers of hydrocarbons of ethene
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/74—Synthetic polymeric materials
- A61K31/765—Polymers containing oxygen
- A61K31/77—Polymers containing oxygen of oxiranes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Pulmonology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Inorganic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US91156397A | 1997-08-14 | 1997-08-14 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR018505A1 true AR018505A1 (es) | 2001-11-28 |
Family
ID=25430473
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP980104005A AR018505A1 (es) | 1997-08-14 | 1998-08-13 | COMPOSICIoN FARMACÉUTICA ANTIHISTAMíNICA CON UN INHIBIDOR DE LA P-GLICOPROTEíNA Y EL USO DE DICHA COMPOSICIoN PARA LA FABRICACIoN DE MEDICAMENTOS PARA AUMENTAR LA BIODISPONIBILIDAD DE DICHO ANTIHISTAMíNICO. |
Country Status (29)
| Country | Link |
|---|---|
| EP (1) | EP1003528B1 (enExample) |
| JP (1) | JP4295913B2 (enExample) |
| KR (1) | KR100522985B1 (enExample) |
| CN (1) | CN1143680C (enExample) |
| AR (1) | AR018505A1 (enExample) |
| AT (1) | ATE224721T1 (enExample) |
| AU (1) | AU725965C (enExample) |
| BR (1) | BR9811937A (enExample) |
| CA (1) | CA2301267C (enExample) |
| CZ (1) | CZ293666B6 (enExample) |
| DE (1) | DE69808303T2 (enExample) |
| DK (1) | DK1003528T3 (enExample) |
| EE (1) | EE04263B1 (enExample) |
| ES (1) | ES2179523T3 (enExample) |
| HU (1) | HU226823B1 (enExample) |
| ID (1) | ID24463A (enExample) |
| IL (1) | IL134521A (enExample) |
| NO (1) | NO325148B1 (enExample) |
| NZ (1) | NZ502133A (enExample) |
| OA (1) | OA11287A (enExample) |
| PL (1) | PL191607B1 (enExample) |
| PT (1) | PT1003528E (enExample) |
| RU (1) | RU2197967C2 (enExample) |
| SK (1) | SK283868B6 (enExample) |
| TR (1) | TR200000419T2 (enExample) |
| TW (1) | TWI240633B (enExample) |
| UA (1) | UA64765C2 (enExample) |
| WO (1) | WO1999008690A1 (enExample) |
| ZA (1) | ZA987221B (enExample) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ302926A (en) * | 1995-02-28 | 1998-10-28 | Hoechst Marion Roussel Inc | Composition for use as antihistamines comprising piperidinoalkanol derivatives and inert ingredients |
| CN1159012C (zh) * | 1997-08-26 | 2004-07-28 | 阿旺蒂斯制药公司 | 用于组合哌啶子基烷醇-减充血剂的药物组合物 |
| GB9822170D0 (en) * | 1998-10-13 | 1998-12-02 | Danbioyst Uk Ltd | Novel formulations of fexofenadine |
| AU2003237253A1 (en) * | 2002-05-29 | 2003-12-19 | Aventis Pharmaceuticals Holdings Inc. | Method of treating asthma using fexofenadine |
| GB0319935D0 (en) * | 2003-08-26 | 2003-09-24 | Cipla Ltd | Polymorphs |
| AR050043A1 (es) * | 2004-08-03 | 2006-09-20 | Novartis Ag | Metodos para mejorar la biodisponibilidad y composicion farmaceutica para trastornos cardiovasculares |
| JP2008120684A (ja) * | 2005-03-07 | 2008-05-29 | Kumamoto Univ | 抗アレルギー薬 |
| KR101106374B1 (ko) | 2009-06-05 | 2012-01-19 | 민병욱 | 고체연료에 의한 가연성 가스 발생 장치 |
| KR101117014B1 (ko) * | 2009-09-09 | 2012-06-14 | 민병욱 | 부패성 폐기물의 바이오매스 처리에 의한 폐자원 재활용 방법 및 장치 |
| CN101843616B (zh) * | 2010-06-04 | 2011-07-27 | 西安万隆制药有限责任公司 | 一种盐酸非索非那定与微晶纤维素组合物及其制备方法 |
| RU2453315C2 (ru) * | 2010-08-17 | 2012-06-20 | Открытое акционерное общество "Химико-фармацевтический комбинат "АКРИХИН" (ОАО "АКРИХИН") | Фармацевтическая композиция для лечения аллергических заболеваний |
| CN103687592A (zh) | 2011-05-20 | 2014-03-26 | 安万特药物公司 | 包含非索非那定的药物组合物 |
| RU2504018C1 (ru) * | 2012-05-28 | 2014-01-10 | Государственное бюджетное образовательное учреждение высшего профессионального образования "Рязанский государственный медицинский университет имени академика И.П. Павлова" Министерства здравоохранения и социального развития Российской Федерации | Способ моделирования состояния индукции функциональной активности гликопротеина-р финастеридом в эксперименте |
| RU2553362C1 (ru) * | 2014-01-09 | 2015-06-10 | Государственное бюджетное образовательное учреждение высшего профессионального образования "Рязанский государственный медицинский университет имени академика И.П. Павлова" Министерства здравоохранения Российской Федерации | Способ моделирования состояния ингибирования функциональной активности гликопротеина-р линестренолом в эксперименте |
| CN104188998A (zh) * | 2014-09-18 | 2014-12-10 | 中山大学 | 一种柚皮苷与盐酸非索非那丁药物组合物及其制剂 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4254129A (en) * | 1979-04-10 | 1981-03-03 | Richardson-Merrell Inc. | Piperidine derivatives |
| KR910007515A (ko) * | 1989-01-31 | 1991-05-30 | 호르스트 카베리쯔 | 부식에 의한 활성제의 서방형 제제 및 그 제조방법 |
| US5567592A (en) * | 1994-02-02 | 1996-10-22 | Regents Of The University Of California | Screening method for the identification of bioenhancers through the inhibition of P-glycoprotein transport in the gut of a mammal |
| AU5893796A (en) * | 1995-06-07 | 1996-12-30 | Novo Nordisk A/S | Modification of polypeptides |
| CA2224227A1 (en) * | 1995-06-07 | 1996-12-19 | Avmax, Inc. | Use of essential oils to increase bioavailability of oral pharmaceutical compounds |
-
1998
- 1998-07-21 CA CA002301267A patent/CA2301267C/en not_active Expired - Lifetime
- 1998-07-21 WO PCT/US1998/015098 patent/WO1999008690A1/en not_active Ceased
- 1998-07-21 ID IDW20000262A patent/ID24463A/id unknown
- 1998-07-21 IL IL13452198A patent/IL134521A/xx not_active IP Right Cessation
- 1998-07-21 RU RU2000106042/14A patent/RU2197967C2/ru active
- 1998-07-21 JP JP2000509429A patent/JP4295913B2/ja not_active Expired - Lifetime
- 1998-07-21 NZ NZ502133A patent/NZ502133A/xx not_active IP Right Cessation
- 1998-07-21 PL PL338579A patent/PL191607B1/pl unknown
- 1998-07-21 PT PT98935892T patent/PT1003528E/pt unknown
- 1998-07-21 UA UA2000031425A patent/UA64765C2/uk unknown
- 1998-07-21 DK DK98935892T patent/DK1003528T3/da active
- 1998-07-21 TR TR2000/00419T patent/TR200000419T2/xx unknown
- 1998-07-21 CZ CZ2000522A patent/CZ293666B6/cs not_active IP Right Cessation
- 1998-07-21 HU HU0003189A patent/HU226823B1/hu unknown
- 1998-07-21 EE EEP200000069A patent/EE04263B1/xx unknown
- 1998-07-21 BR BR9811937-0A patent/BR9811937A/pt not_active Application Discontinuation
- 1998-07-21 AU AU85050/98A patent/AU725965C/en not_active Expired
- 1998-07-21 AT AT98935892T patent/ATE224721T1/de active
- 1998-07-21 SK SK184-2000A patent/SK283868B6/sk not_active IP Right Cessation
- 1998-07-21 ES ES98935892T patent/ES2179523T3/es not_active Expired - Lifetime
- 1998-07-21 DE DE69808303T patent/DE69808303T2/de not_active Expired - Lifetime
- 1998-07-21 CN CNB988081598A patent/CN1143680C/zh not_active Expired - Lifetime
- 1998-07-21 KR KR10-2000-7001447A patent/KR100522985B1/ko not_active Expired - Lifetime
- 1998-07-21 EP EP98935892A patent/EP1003528B1/en not_active Expired - Lifetime
- 1998-08-12 ZA ZA987221A patent/ZA987221B/xx unknown
- 1998-08-13 AR ARP980104005A patent/AR018505A1/es active IP Right Grant
- 1998-11-05 TW TW087113210A patent/TWI240633B/zh not_active IP Right Cessation
-
2000
- 2000-02-09 OA OA1200000032A patent/OA11287A/en unknown
- 2000-02-11 NO NO20000706A patent/NO325148B1/no not_active IP Right Cessation
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant, registration |