ATE224721T1 - Verfahren zur verbesserung der bioverfügbarkeit des fexofenadins und seiner derivate - Google Patents

Verfahren zur verbesserung der bioverfügbarkeit des fexofenadins und seiner derivate

Info

Publication number
ATE224721T1
ATE224721T1 AT98935892T AT98935892T ATE224721T1 AT E224721 T1 ATE224721 T1 AT E224721T1 AT 98935892 T AT98935892 T AT 98935892T AT 98935892 T AT98935892 T AT 98935892T AT E224721 T1 ATE224721 T1 AT E224721T1
Authority
AT
Austria
Prior art keywords
fexofenadine
bioavailability
derivatives
improving
Prior art date
Application number
AT98935892T
Other languages
English (en)
Inventor
Kin-Kai Hwang
Dennis H Giesing
Gail H Hurst
Original Assignee
Aventis Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Inc filed Critical Aventis Pharma Inc
Application granted granted Critical
Publication of ATE224721T1 publication Critical patent/ATE224721T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/745—Polymers of hydrocarbons
    • A61K31/75—Polymers of hydrocarbons of ethene
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/765—Polymers containing oxygen
    • A61K31/77—Polymers containing oxygen of oxiranes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
AT98935892T 1997-08-14 1998-07-21 Verfahren zur verbesserung der bioverfügbarkeit des fexofenadins und seiner derivate ATE224721T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US91156397A 1997-08-14 1997-08-14
PCT/US1998/015098 WO1999008690A1 (en) 1997-08-14 1998-07-21 Method of enhancing bioavailability of fexofenadine and its derivatives

Publications (1)

Publication Number Publication Date
ATE224721T1 true ATE224721T1 (de) 2002-10-15

Family

ID=25430473

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98935892T ATE224721T1 (de) 1997-08-14 1998-07-21 Verfahren zur verbesserung der bioverfügbarkeit des fexofenadins und seiner derivate

Country Status (30)

Country Link
EP (1) EP1003528B1 (de)
JP (1) JP4295913B2 (de)
KR (1) KR100522985B1 (de)
CN (1) CN1143680C (de)
AR (1) AR018505A1 (de)
AT (1) ATE224721T1 (de)
AU (1) AU725965C (de)
BR (1) BR9811937A (de)
CA (1) CA2301267C (de)
CZ (1) CZ293666B6 (de)
DE (1) DE69808303T2 (de)
DK (1) DK1003528T3 (de)
EE (1) EE04263B1 (de)
ES (1) ES2179523T3 (de)
HK (1) HK1025901A1 (de)
HU (1) HU226823B1 (de)
ID (1) ID24463A (de)
IL (1) IL134521A (de)
NO (1) NO325148B1 (de)
NZ (1) NZ502133A (de)
OA (1) OA11287A (de)
PL (1) PL191607B1 (de)
PT (1) PT1003528E (de)
RU (1) RU2197967C2 (de)
SK (1) SK283868B6 (de)
TR (1) TR200000419T2 (de)
TW (1) TWI240633B (de)
UA (1) UA64765C2 (de)
WO (1) WO1999008690A1 (de)
ZA (1) ZA987221B (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX9706449A (es) * 1995-02-28 1997-11-29 Hoechst Marion Roussel Inc Composicion farmaceutica para compuestos de piperidinalcanol.
ATE238773T1 (de) * 1997-08-26 2003-05-15 Aventis Pharma Inc Arzneimittel für die kombination piperidinoalkanol-dekongestivum
GB9822170D0 (en) * 1998-10-13 1998-12-02 Danbioyst Uk Ltd Novel formulations of fexofenadine
BR0306329A (pt) * 2002-05-29 2005-04-26 Aventis Pharmaceuticals Holdin Método de tratamento de asma
JP2008120684A (ja) * 2005-03-07 2008-05-29 Kumamoto Univ 抗アレルギー薬
KR101106374B1 (ko) 2009-06-05 2012-01-19 민병욱 고체연료에 의한 가연성 가스 발생 장치
KR101117014B1 (ko) * 2009-09-09 2012-06-14 민병욱 부패성 폐기물의 바이오매스 처리에 의한 폐자원 재활용 방법 및 장치
CN101843616B (zh) * 2010-06-04 2011-07-27 西安万隆制药有限责任公司 一种盐酸非索非那定与微晶纤维素组合物及其制备方法
RU2453315C2 (ru) * 2010-08-17 2012-06-20 Открытое акционерное общество "Химико-фармацевтический комбинат "АКРИХИН" (ОАО "АКРИХИН") Фармацевтическая композиция для лечения аллергических заболеваний
BR112013029778A2 (pt) 2011-05-20 2017-01-17 Aventis Pharma Inc composição farmacêutica que compreende fexofenadina
RU2504018C1 (ru) * 2012-05-28 2014-01-10 Государственное бюджетное образовательное учреждение высшего профессионального образования "Рязанский государственный медицинский университет имени академика И.П. Павлова" Министерства здравоохранения и социального развития Российской Федерации Способ моделирования состояния индукции функциональной активности гликопротеина-р финастеридом в эксперименте
RU2553362C1 (ru) * 2014-01-09 2015-06-10 Государственное бюджетное образовательное учреждение высшего профессионального образования "Рязанский государственный медицинский университет имени академика И.П. Павлова" Министерства здравоохранения Российской Федерации Способ моделирования состояния ингибирования функциональной активности гликопротеина-р линестренолом в эксперименте
CN104188998A (zh) * 2014-09-18 2014-12-10 中山大学 一种柚皮苷与盐酸非索非那丁药物组合物及其制剂

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5567592A (en) * 1994-02-02 1996-10-22 Regents Of The University Of California Screening method for the identification of bioenhancers through the inhibition of P-glycoprotein transport in the gut of a mammal
CA2224227A1 (en) * 1995-06-07 1996-12-19 Avmax, Inc. Use of essential oils to increase bioavailability of oral pharmaceutical compounds
WO1996040792A1 (en) * 1995-06-07 1996-12-19 Novo Nordisk A/S Modification of polypeptides

Also Published As

Publication number Publication date
EE200000069A (et) 2000-10-16
PL338579A1 (en) 2000-11-06
CA2301267A1 (en) 1999-02-25
CZ2000522A3 (cs) 2000-09-13
ZA987221B (en) 1999-02-15
CZ293666B6 (cs) 2004-06-16
RU2197967C2 (ru) 2003-02-10
PL191607B1 (pl) 2006-06-30
CN1267221A (zh) 2000-09-20
HU226823B1 (hu) 2009-11-30
IL134521A0 (en) 2001-04-30
AR018505A1 (es) 2001-11-28
NO20000706D0 (no) 2000-02-11
DK1003528T3 (da) 2003-02-03
WO1999008690A1 (en) 1999-02-25
BR9811937A (pt) 2000-09-05
NZ502133A (en) 2002-03-28
JP4295913B2 (ja) 2009-07-15
KR100522985B1 (ko) 2005-10-21
CA2301267C (en) 2004-07-13
AU725965B2 (en) 2000-10-26
HUP0003189A2 (en) 2001-03-28
AU725965C (en) 2004-04-22
TR200000419T2 (tr) 2000-09-21
ES2179523T3 (es) 2003-01-16
IL134521A (en) 2005-07-25
AU8505098A (en) 1999-03-08
HUP0003189A3 (en) 2001-04-28
ID24463A (id) 2000-07-20
UA64765C2 (uk) 2004-03-15
HK1025901A1 (en) 2000-12-01
CN1143680C (zh) 2004-03-31
EP1003528B1 (de) 2002-09-25
EP1003528A1 (de) 2000-05-31
OA11287A (en) 2003-10-22
SK283868B6 (sk) 2004-03-02
SK1842000A3 (en) 2000-08-14
EE04263B1 (et) 2004-04-15
TWI240633B (en) 2005-10-01
KR20010022845A (ko) 2001-03-26
DE69808303T2 (de) 2003-05-22
PT1003528E (pt) 2003-02-28
NO20000706L (no) 2000-04-13
JP2001515041A (ja) 2001-09-18
DE69808303D1 (de) 2002-10-31
NO325148B1 (no) 2008-02-11

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