AR015105A1 - Una composicion que comprende derivados de urea o carbonato y factores neurotroficos para estimular el crecimiento de neuritas en celulas nerviosas y unmedicamento que la comprende - Google Patents
Una composicion que comprende derivados de urea o carbonato y factores neurotroficos para estimular el crecimiento de neuritas en celulas nerviosas y unmedicamento que la comprendeInfo
- Publication number
- AR015105A1 AR015105A1 ARP970105320A ARP970105320A AR015105A1 AR 015105 A1 AR015105 A1 AR 015105A1 AR P970105320 A ARP970105320 A AR P970105320A AR P970105320 A ARP970105320 A AR P970105320A AR 015105 A1 AR015105 A1 AR 015105A1
- Authority
- AR
- Argentina
- Prior art keywords
- growth
- neurites
- stimulate
- understands
- medicine
- Prior art date
Links
- 108010025020 Nerve Growth Factor Proteins 0.000 title abstract 5
- 239000000203 mixture Substances 0.000 title abstract 5
- 102000007072 Nerve Growth Factors Human genes 0.000 title abstract 3
- 239000003900 neurotrophic factor Substances 0.000 title abstract 3
- 210000002241 neurite Anatomy 0.000 title abstract 2
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 title 1
- 239000004202 carbamide Substances 0.000 title 1
- BVKZGUZCCUSVTD-UHFFFAOYSA-N carbonic acid Chemical class OC(O)=O BVKZGUZCCUSVTD-UHFFFAOYSA-N 0.000 title 1
- 210000004027 cell Anatomy 0.000 title 1
- 102000015336 Nerve Growth Factor Human genes 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 229940053128 nerve growth factor Drugs 0.000 abstract 2
- 210000002569 neuron Anatomy 0.000 abstract 2
- 208000014674 injury Diseases 0.000 abstract 1
- 230000003961 neuronal insult Effects 0.000 abstract 1
- 230000000508 neurotrophic effect Effects 0.000 abstract 1
- 230000008733 trauma Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/185—Nerve growth factor [NGF]; Brain derived neurotrophic factor [BDNF]; Ciliary neurotrophic factor [CNTF]; Glial derived neurotrophic factor [GDNF]; Neurotrophins, e.g. NT-3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Psychology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/749,114 US5780484A (en) | 1996-11-13 | 1996-11-13 | Methods for stimulating neurite growth with piperidine compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR015105A1 true AR015105A1 (es) | 2001-04-18 |
Family
ID=25012320
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP970105320A AR015105A1 (es) | 1996-11-13 | 1997-11-13 | Una composicion que comprende derivados de urea o carbonato y factores neurotroficos para estimular el crecimiento de neuritas en celulas nerviosas y unmedicamento que la comprende |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US5780484A (OSRAM) |
| EP (2) | EP1666053A1 (OSRAM) |
| JP (1) | JP2001503778A (OSRAM) |
| KR (1) | KR100537866B1 (OSRAM) |
| CN (1) | CN1168443C (OSRAM) |
| AR (1) | AR015105A1 (OSRAM) |
| AU (1) | AU741186B2 (OSRAM) |
| BR (1) | BR9713037A (OSRAM) |
| CA (1) | CA2270985A1 (OSRAM) |
| CO (1) | CO5080733A1 (OSRAM) |
| EA (1) | EA003530B1 (OSRAM) |
| IL (1) | IL129557A0 (OSRAM) |
| IN (1) | IN183409B (OSRAM) |
| NZ (1) | NZ335396A (OSRAM) |
| PL (1) | PL191249B1 (OSRAM) |
| TW (1) | TW509572B (OSRAM) |
| UA (1) | UA61090C2 (OSRAM) |
| WO (1) | WO1998020893A1 (OSRAM) |
| ZA (1) | ZA9710248B (OSRAM) |
Families Citing this family (43)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6150527A (en) * | 1994-08-18 | 2000-11-21 | Ariad Pharmaceuticals, Inc. | Synthetic multimerizing agents |
| US6133456A (en) * | 1994-08-18 | 2000-10-17 | Ariad Gene Therapeutics, Inc. | Synthetic multimerizing agents |
| US20030036654A1 (en) * | 1994-08-18 | 2003-02-20 | Holt Dennis A. | Synthetic multimerizing agents |
| US5859031A (en) | 1995-06-07 | 1999-01-12 | Gpi Nil Holdings, Inc. | Small molecule inhibitors of rotamase enzyme activity |
| US6242468B1 (en) * | 1997-02-27 | 2001-06-05 | Jia-He Li | Carbamate and urea compositions and neurotrophic uses |
| ZA98825B (en) * | 1997-02-27 | 1998-10-19 | Guilford Pharm Inc | Method of using neurotrophic carbamates and ureas |
| US6514686B2 (en) | 1997-04-28 | 2003-02-04 | The University Of British Columbia | Method and composition for modulating amyloidosis |
| US5945441A (en) | 1997-06-04 | 1999-08-31 | Gpi Nil Holdings, Inc. | Pyrrolidine carboxylate hair revitalizing agents |
| US20010049381A1 (en) | 1997-06-04 | 2001-12-06 | Gpl Nil Holdings, Inc., | Pyrrolidine derivative hair growth compositions and uses |
| US6852496B1 (en) | 1997-08-12 | 2005-02-08 | Oregon Health And Science University | Methods of screening for agents that promote nerve cell growth |
| US5968921A (en) | 1997-10-24 | 1999-10-19 | Orgegon Health Sciences University | Compositions and methods for promoting nerve regeneration |
| PL348671A1 (en) * | 1998-06-03 | 2002-06-03 | Gpi Nil Holdings | Ureas and carbamates of n-heterocyclic carboxylic acids and carboxylic acid isosteres |
| US6331537B1 (en) | 1998-06-03 | 2001-12-18 | Gpi Nil Holdings, Inc. | Carboxylic acids and carboxylic acid isosteres of N-heterocyclic compounds |
| WO1999062880A1 (en) | 1998-06-03 | 1999-12-09 | Gpi Nil Holdings, Inc. | N-linked sulfonamides of n-heterocyclic carboxylic acids or carboxylic acid isosteres |
| IL140676A0 (en) | 1998-07-17 | 2002-02-10 | Agouron Pharma | Compounds, compositions, and methods for stimulating neuronal growth and elongation |
| GB9815880D0 (en) | 1998-07-21 | 1998-09-16 | Pfizer Ltd | Heterocycles |
| US7338976B1 (en) * | 1998-08-14 | 2008-03-04 | Gpi Nil Holdings, Inc. | Heterocyclic esters or amides for vision and memory disorders |
| US6376517B1 (en) * | 1998-08-14 | 2002-04-23 | Gpi Nil Holdings, Inc. | Pipecolic acid derivatives for vision and memory disorders |
| US6395758B1 (en) | 1998-08-14 | 2002-05-28 | Gpi Nil Holdings, Inc. | Small molecule carbamates or ureas for vision and memory disorders |
| US6462072B1 (en) | 1998-09-21 | 2002-10-08 | Gpi Nil Holdings, Inc. | Cyclic ester or amide derivatives |
| US6228872B1 (en) | 1998-11-12 | 2001-05-08 | Bristol-Myers Squibb Company | Neurotrophic diamide and carbamate agents |
| WO2001002368A1 (en) * | 1999-07-06 | 2001-01-11 | Vertex Pharmaceuticals Incorporated | N-heterocyclic derivatives with neuronal activity |
| RU2241709C2 (ru) | 1999-07-09 | 2004-12-10 | Орто-Макнейл Фармасьютикал, Инк. | Производные азотсодержащих гетероциклических соединений и способ лечения расстройств, характеризующихся поражением нейронов |
| US6734211B1 (en) * | 1999-07-09 | 2004-05-11 | Oregon Health & Sciences University | Compositions and methods for promoting nerve regeneration |
| AU7353300A (en) | 1999-09-08 | 2001-04-10 | Guilford Pharmaceuticals Inc. | Non-peptidic cyclophilin binding compounds and their use |
| US6417189B1 (en) | 1999-11-12 | 2002-07-09 | Gpi Nil Holdings, Inc. | AZA compounds, pharmaceutical compositions and methods of use |
| ATE335524T1 (de) * | 1999-11-12 | 2006-09-15 | Alcon Inc | Verwendung von neurophilin liganden zur behandlung von augenerkrankungen |
| US7253169B2 (en) | 1999-11-12 | 2007-08-07 | Gliamed, Inc. | Aza compounds, pharmaceutical compositions and methods of use |
| US6818643B1 (en) | 1999-12-08 | 2004-11-16 | Bristol-Myers Squibb Company | Neurotrophic bicyclic diamides |
| EP1244670B1 (en) | 1999-12-21 | 2006-03-08 | MGI GP, Inc. | Hydantoin derivative compounds, pharmaceutical compositions, and methods of using same |
| MXPA03006666A (es) | 2001-01-25 | 2004-05-31 | Guilford Pharm Inc | Compuestos de union de ciclofilina carbociclicos trisubstituidos y su uso. |
| EP1404325A2 (en) * | 2001-05-29 | 2004-04-07 | Guilford Pharmaceuticals Inc. | Method for treating nerve injury caused by surgery |
| US20040147433A1 (en) * | 2001-06-14 | 2004-07-29 | Marcus Keep | Neuroimmunophilins for selective neuronal radioprotection |
| US6635892B2 (en) * | 2002-01-24 | 2003-10-21 | Pei Electronics, Inc. | Compact integrated infrared scene projector |
| MXPA05003471A (es) * | 2002-10-03 | 2005-07-01 | Vertex Pharma | Derivados de piperazina y piperadina para el tratamiento de enfermedades neurologicas. |
| US20060189551A1 (en) * | 2004-10-04 | 2006-08-24 | Duke University | Combination therapies for fungal pathogens |
| SG158143A1 (en) * | 2004-12-20 | 2010-01-29 | Wyeth Corp | Rapamycin analogues and the uses thereof in the treatment of neurological, proliferative, and inflammatory disorders |
| RU2007119585A (ru) * | 2004-12-20 | 2009-01-27 | Вайет (Us) | Производные рапамицина и их применение при лечении неврологических заболеваний |
| MX2007010076A (es) * | 2005-02-17 | 2007-10-16 | Astellas Pharma Inc | Derivado de heterociclico-1-carboxilato que contiene nitrogeno no aromatico de piridilo. |
| CA2637707A1 (en) * | 2006-02-02 | 2007-08-09 | Rinat Neuroscience Corporation | Methods for treating obesity by administering a trkb antagonist |
| CN101400367A (zh) * | 2006-02-02 | 2009-04-01 | 瑞纳神经科学公司 | 施用trkb激动剂治疗不希望的重量减轻或进食障碍的方法 |
| JP2021525737A (ja) | 2018-05-30 | 2021-09-27 | ザップ サージカル システムズ, インコーポレイテッド | 重要構造近くにおける放射線外科的神経調節 |
| CN116763768B (zh) * | 2022-03-15 | 2026-03-20 | 润佳(苏州)医药科技有限公司 | 同位素富集的3-氨基-1-丙磺酸衍生物及其用途 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5192773A (en) * | 1990-07-02 | 1993-03-09 | Vertex Pharmaceuticals, Inc. | Immunosuppressive compounds |
| HU217621B (hu) * | 1991-05-09 | 2000-03-28 | Vertex Pharmaceuticals Inc. | Eljárás új glioxaloil-pipekolinsav-észterek, származékaik és az ezeket tartalmazó gyógyszerkészítmények előállítására |
| NZ314207A (en) * | 1992-09-28 | 2000-12-22 | Vertex Pharma | 1-(2-Oxoacetyl)-piperidine-2-carboxylic acid derivatives as multi drug resistant cancer cell sensitizers |
| US5744485A (en) * | 1994-03-25 | 1998-04-28 | Vertex Pharmaceuticals Incorporated | Carbamates and ureas as modifiers of multi-drug resistance |
| IL115685A (en) * | 1994-11-16 | 2000-08-31 | Vertex Pharma | Amino acid derivatives pharmaceutical compositions containing the same and processes for the preparation thereof |
| US5543423A (en) * | 1994-11-16 | 1996-08-06 | Vertex Pharmaceuticals, Incorporated | Amino acid derivatives with improved multi-drug resistance activity |
| US5726184A (en) * | 1995-05-19 | 1998-03-10 | Vertex Pharmaceuticals Incorporated | Tetralin compounds with improved MDR activity |
| US5614547A (en) * | 1995-06-07 | 1997-03-25 | Guilford Pharmaceuticals Inc. | Small molecule inhibitors of rotamase enzyme |
| US5696135A (en) * | 1995-06-07 | 1997-12-09 | Gpi Nil Holdings, Inc. | Inhibitors of rotamase enzyme activity effective at stimulating neuronal growth |
| US5859031A (en) * | 1995-06-07 | 1999-01-12 | Gpi Nil Holdings, Inc. | Small molecule inhibitors of rotamase enzyme activity |
| US6037370A (en) * | 1995-06-08 | 2000-03-14 | Vertex Pharmaceuticals Incorporated | Methods and compositions for stimulating neurite growth |
| US5801197A (en) * | 1995-10-31 | 1998-09-01 | Gpi Nil Holdings, Inc. | Rotamase enzyme activity inhibitors |
| US5840736A (en) * | 1996-11-13 | 1998-11-24 | Vertex Pharmaceuticals Incorporated | Methods and compositions for stimulating neurite growth |
| US5811434A (en) * | 1996-11-13 | 1998-09-22 | Vertex Pharmacueticals Incorporated | Methods and compositions for stimulating neurite growth |
| CN104718162B (zh) * | 2012-09-28 | 2017-11-21 | Dic株式会社 | α‑氧化铝微粒以及其制造方法 |
-
1996
- 1996-11-13 US US08/749,114 patent/US5780484A/en not_active Expired - Lifetime
-
1997
- 1997-11-13 WO PCT/US1997/020868 patent/WO1998020893A1/en not_active Ceased
- 1997-11-13 CA CA002270985A patent/CA2270985A1/en not_active Abandoned
- 1997-11-13 TW TW086116912A patent/TW509572B/zh not_active IP Right Cessation
- 1997-11-13 IN IN2147CA1997 patent/IN183409B/en unknown
- 1997-11-13 AU AU54397/98A patent/AU741186B2/en not_active Ceased
- 1997-11-13 UA UA99063269A patent/UA61090C2/uk unknown
- 1997-11-13 PL PL333286A patent/PL191249B1/pl not_active IP Right Cessation
- 1997-11-13 BR BR9713037-0A patent/BR9713037A/pt not_active Application Discontinuation
- 1997-11-13 JP JP52286798A patent/JP2001503778A/ja active Pending
- 1997-11-13 EP EP06000328A patent/EP1666053A1/en not_active Ceased
- 1997-11-13 CO CO97066753A patent/CO5080733A1/es unknown
- 1997-11-13 AR ARP970105320A patent/AR015105A1/es not_active Application Discontinuation
- 1997-11-13 NZ NZ335396A patent/NZ335396A/xx unknown
- 1997-11-13 EA EA199900463A patent/EA003530B1/ru not_active IP Right Cessation
- 1997-11-13 KR KR10-1999-7004194A patent/KR100537866B1/ko not_active Expired - Fee Related
- 1997-11-13 EP EP97948309A patent/EP0941113A1/en not_active Ceased
- 1997-11-13 CN CNB971802483A patent/CN1168443C/zh not_active Expired - Fee Related
- 1997-11-13 IL IL12955797A patent/IL129557A0/xx not_active IP Right Cessation
- 1997-11-13 ZA ZA9710248A patent/ZA9710248B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO1998020893A1 (en) | 1998-05-22 |
| NZ335396A (en) | 2000-11-24 |
| IN183409B (OSRAM) | 1999-12-25 |
| PL191249B1 (pl) | 2006-04-28 |
| EA199900463A1 (ru) | 2000-02-28 |
| KR20000068964A (ko) | 2000-11-25 |
| US5780484A (en) | 1998-07-14 |
| CN1239434A (zh) | 1999-12-22 |
| EP1666053A1 (en) | 2006-06-07 |
| CA2270985A1 (en) | 1998-05-22 |
| EA003530B1 (ru) | 2003-06-26 |
| ZA9710248B (en) | 1998-05-28 |
| AU5439798A (en) | 1998-06-03 |
| AU741186B2 (en) | 2001-11-22 |
| KR100537866B1 (ko) | 2005-12-21 |
| IL129557A0 (en) | 2000-02-29 |
| CO5080733A1 (es) | 2001-09-25 |
| JP2001503778A (ja) | 2001-03-21 |
| BR9713037A (pt) | 2000-04-11 |
| PL333286A1 (en) | 1999-11-22 |
| EP0941113A1 (en) | 1999-09-15 |
| TW509572B (en) | 2002-11-11 |
| UA61090C2 (uk) | 2003-11-17 |
| CN1168443C (zh) | 2004-09-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC | Refusal |