AR011126A1 - Procedimiento para preparar eprosartano y compuestos intermediarios. - Google Patents

Procedimiento para preparar eprosartano y compuestos intermediarios.

Info

Publication number
AR011126A1
AR011126A1 ARP980100586A ARP980100586A AR011126A1 AR 011126 A1 AR011126 A1 AR 011126A1 AR P980100586 A ARP980100586 A AR P980100586A AR P980100586 A ARP980100586 A AR P980100586A AR 011126 A1 AR011126 A1 AR 011126A1
Authority
AR
Argentina
Prior art keywords
compound
formula
nitrogen
4alkyl
reacting
Prior art date
Application number
ARP980100586A
Other languages
English (en)
Spanish (es)
Original Assignee
Smithkline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Corp filed Critical Smithkline Beecham Corp
Publication of AR011126A1 publication Critical patent/AR011126A1/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ARP980100586A 1997-02-14 1998-02-10 Procedimiento para preparar eprosartano y compuestos intermediarios. AR011126A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US3819697P 1997-02-14 1997-02-14

Publications (1)

Publication Number Publication Date
AR011126A1 true AR011126A1 (es) 2000-08-02

Family

ID=21898590

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP980100586A AR011126A1 (es) 1997-02-14 1998-02-10 Procedimiento para preparar eprosartano y compuestos intermediarios.

Country Status (41)

Country Link
US (2) US6294675B1 (cs)
EP (1) EP0973769B1 (cs)
JP (1) JP4227671B2 (cs)
KR (1) KR100551667B1 (cs)
CN (1) CN1093128C (cs)
AP (1) AP1202A (cs)
AR (1) AR011126A1 (cs)
AT (1) ATE274511T1 (cs)
AU (1) AU730162B2 (cs)
BG (1) BG63970B1 (cs)
BR (1) BRPI9808642B8 (cs)
CA (1) CA2281471C (cs)
CO (1) CO4950549A1 (cs)
CY (1) CY2551B1 (cs)
CZ (1) CZ296543B6 (cs)
DE (1) DE69825880T2 (cs)
DK (1) DK0973769T3 (cs)
DZ (1) DZ2418A1 (cs)
EA (1) EA001761B1 (cs)
EG (1) EG23780A (cs)
ES (1) ES2224358T3 (cs)
HK (1) HK1026206A1 (cs)
HU (1) HU228098B1 (cs)
ID (1) ID23155A (cs)
IL (4) IL143784A (cs)
IN (1) IN188000B (cs)
MA (1) MA24472A1 (cs)
MY (1) MY120024A (cs)
NO (1) NO317761B1 (cs)
NZ (1) NZ337182A (cs)
OA (1) OA11086A (cs)
PE (1) PE59799A1 (cs)
PL (1) PL192837B1 (cs)
PT (1) PT973769E (cs)
SA (1) SA98190146B1 (cs)
SI (1) SI0973769T1 (cs)
SK (1) SK285125B6 (cs)
TR (1) TR199901935T2 (cs)
UA (1) UA57060C2 (cs)
WO (1) WO1998035962A1 (cs)
ZA (1) ZA981208B (cs)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR011126A1 (es) * 1997-02-14 2000-08-02 Smithkline Beecham Corp Procedimiento para preparar eprosartano y compuestos intermediarios.
US6630498B2 (en) * 1997-08-06 2003-10-07 Smithkline Beecham Corporation Eprosartan arginyl charge-neutralization-complex and a process for its preparation and formulation
TR200100172T2 (tr) * 1998-07-20 2001-05-21 Smithkline Beecham Corporation Oral katı doz formunda eprosartan içeren biyolojik bakımdan kuvvetlendirilmiş formülasyonlar
US20060099230A1 (en) * 2004-11-10 2006-05-11 Chin-Chih Chiang Novel formulations of eprosartan with enhanced bioavailability
US20100137613A1 (en) * 2006-12-27 2010-06-03 Hetero Drugs Limited Process for eprosartan
RU2453536C2 (ru) * 2007-10-22 2012-06-20 Оркид Рисерч Лабораториз Лимитед Ингибиторы гистондезацетилазы
CN101215284B (zh) * 2007-12-31 2010-10-13 浙江华海药业股份有限公司 一种改进的依普罗沙坦的制备方法
WO2011004384A2 (en) 2009-06-05 2011-01-13 Glochem Industries Limited Process for the preparation of eprosartan
CN102584709B (zh) * 2011-12-19 2016-08-17 浙江华海药业股份有限公司 一种改进的依普罗沙坦中间体芳基咪唑醛的制备工艺
CN103288742A (zh) * 2013-06-04 2013-09-11 四川百利药业有限责任公司 一种高纯度英加韦林原料的制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5185351A (en) * 1989-06-14 1993-02-09 Smithkline Beecham Corporation Imidazolyl-alkenoic acids useful as angiotensin II receptor antagonists
DE69034103T2 (de) * 1989-06-14 2004-07-15 Smithkline Beecham Corp. Imidazoalkensäure
US5418250A (en) * 1989-06-14 1995-05-23 Smithkline Beecham Corporation Imidazolyl-alkenoic acids useful as angiotensin II receptor antagonists
NZ239161A (en) * 1990-07-31 1994-01-26 Smithkline Beecham Corp Substituted [1h-imidazol-5-yl] alkanoic acid derivatives; medicaments,
JP3214856B2 (ja) 1990-12-14 2001-10-02 スミスクライン・ビーチャム・コーポレイション イミダゾリル−アルケン酸
AR011126A1 (es) * 1997-02-14 2000-08-02 Smithkline Beecham Corp Procedimiento para preparar eprosartano y compuestos intermediarios.

Also Published As

Publication number Publication date
CA2281471A1 (en) 1998-08-20
CN1247538A (zh) 2000-03-15
SK108699A3 (en) 2000-05-16
DK0973769T3 (da) 2004-12-13
EA199900741A1 (ru) 2000-02-28
CZ285199A3 (cs) 2000-02-16
SI0973769T1 (en) 2004-12-31
HK1026206A1 (en) 2000-12-08
NO993912L (no) 1999-08-13
AP9901619A0 (en) 1999-09-30
PL335074A1 (en) 2000-04-10
BG103649A (en) 2000-06-30
ID23155A (id) 2000-03-23
DZ2418A1 (fr) 2003-06-26
IL143783A (en) 2005-05-17
ES2224358T3 (es) 2005-03-01
HU228098B1 (en) 2012-10-29
DE69825880T2 (de) 2005-09-08
BRPI9808642B8 (pt) 2021-05-25
JP2001511808A (ja) 2001-08-14
SK285125B6 (sk) 2006-06-01
IL143785A (en) 2004-12-15
HUP0001813A2 (hu) 2001-06-28
EA001761B1 (ru) 2001-08-27
IL131310A0 (en) 2001-01-28
NZ337182A (en) 2001-04-27
OA11086A (en) 2003-03-13
JP4227671B2 (ja) 2009-02-18
EP0973769A4 (en) 2001-01-24
DE69825880D1 (de) 2004-09-30
US6294675B1 (en) 2001-09-25
IL143784A0 (en) 2002-04-21
CO4950549A1 (es) 2000-09-01
EG23780A (en) 2007-08-13
MY120024A (en) 2005-08-30
PT973769E (pt) 2004-11-30
IL131310A (en) 2003-02-12
EP0973769A1 (en) 2000-01-26
US20020028951A1 (en) 2002-03-07
NO993912D0 (no) 1999-08-13
AP1202A (en) 2003-09-02
KR100551667B1 (ko) 2006-02-13
UA57060C2 (uk) 2003-06-16
PE59799A1 (es) 1999-08-06
CA2281471C (en) 2007-04-24
AU6273298A (en) 1998-09-08
BR9808642A (pt) 2000-05-23
SA98190146B1 (ar) 2006-08-20
HUP0001813A3 (en) 2001-07-30
CZ296543B6 (cs) 2006-04-12
BR9808642B1 (pt) 2013-11-26
AU730162B2 (en) 2001-03-01
CY2551B1 (en) 2008-07-02
IL143785A0 (en) 2002-04-21
NO317761B1 (no) 2004-12-13
MA24472A1 (fr) 1998-10-01
EP0973769B1 (en) 2004-08-25
IL143784A (en) 2005-05-17
PL192837B1 (pl) 2006-12-29
IL143783A0 (en) 2002-04-21
US6458963B1 (en) 2002-10-01
KR20000071008A (ko) 2000-11-25
ZA981208B (en) 1998-11-12
TR199901935T2 (xx) 1999-12-21
BG63970B1 (bg) 2003-08-29
IN188000B (cs) 2002-08-03
ATE274511T1 (de) 2004-09-15
CN1093128C (zh) 2002-10-23
WO1998035962A1 (en) 1998-08-20

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