ATE327994T1 - Meso-substituierte tripyrrane derivate, zusammensetzungen und verwendungsmöglichkeiten sowie verfahren zu deren herstellung - Google Patents
Meso-substituierte tripyrrane derivate, zusammensetzungen und verwendungsmöglichkeiten sowie verfahren zu deren herstellungInfo
- Publication number
- ATE327994T1 ATE327994T1 AT97903180T AT97903180T ATE327994T1 AT E327994 T1 ATE327994 T1 AT E327994T1 AT 97903180 T AT97903180 T AT 97903180T AT 97903180 T AT97903180 T AT 97903180T AT E327994 T1 ATE327994 T1 AT E327994T1
- Authority
- AT
- Austria
- Prior art keywords
- group
- formula
- meso
- derivatives
- compositions
- Prior art date
Links
- GGSGPPFRVNQBCV-UHFFFAOYSA-N 2,5-bis(1h-pyrrol-2-ylmethyl)-1h-pyrrole Chemical class C=1C=C(CC=2NC=CC=2)NC=1CC1=CC=CN1 GGSGPPFRVNQBCV-UHFFFAOYSA-N 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 239000000203 mixture Chemical class 0.000 title 1
- KAESVJOAVNADME-UHFFFAOYSA-N Pyrrole Chemical compound C=1C=CNC=1 KAESVJOAVNADME-UHFFFAOYSA-N 0.000 abstract 4
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 3
- 125000003118 aryl group Chemical group 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 1
- 125000003158 alcohol group Chemical group 0.000 abstract 1
- 239000006227 byproduct Substances 0.000 abstract 1
- 125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 abstract 1
- 230000003197 catalytic effect Effects 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- PBTPREHATAFBEN-UHFFFAOYSA-N dipyrromethane Chemical compound C=1C=CNC=1CC1=CC=CN1 PBTPREHATAFBEN-UHFFFAOYSA-N 0.000 abstract 1
- 230000008020 evaporation Effects 0.000 abstract 1
- 238000001704 evaporation Methods 0.000 abstract 1
- 125000001072 heteroaryl group Chemical group 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 125000006413 ring segment Chemical group 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D207/323—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to the ring nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pyrrole Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Polyoxymethylene Polymers And Polymers With Carbon-To-Carbon Bonds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Compounds Of Unknown Constitution (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US61221596A | 1996-03-07 | 1996-03-07 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE327994T1 true ATE327994T1 (de) | 2006-06-15 |
Family
ID=24452223
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT97903180T ATE327994T1 (de) | 1996-03-07 | 1997-02-25 | Meso-substituierte tripyrrane derivate, zusammensetzungen und verwendungsmöglichkeiten sowie verfahren zu deren herstellung |
Country Status (9)
| Country | Link |
|---|---|
| US (3) | US5883246A (de) |
| EP (1) | EP0885228B1 (de) |
| JP (1) | JP2001511112A (de) |
| AT (1) | ATE327994T1 (de) |
| AU (1) | AU1762597A (de) |
| DE (1) | DE69735992T2 (de) |
| ES (1) | ES2267129T3 (de) |
| TW (1) | TW502036B (de) |
| WO (1) | WO1997032884A1 (de) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5883246A (en) * | 1996-03-07 | 1999-03-16 | Qlt Phototherapeutics, Inc. | Synthesis of polypyrrolic macrocycles from meso-substituted tripyrrane compounds |
| US20020022032A1 (en) * | 1999-04-23 | 2002-02-21 | Curry Patrick Mark | Immuno-adjuvant PDT treatment of metastatic tumors |
| US6316264B1 (en) | 1999-12-17 | 2001-11-13 | Bayer Corporation | Test strip for the assay of an analyte in a liquid sample |
| US6693093B2 (en) * | 2000-05-08 | 2004-02-17 | The University Of British Columbia (Ubc) | Drug delivery systems for photodynamic therapy |
| US7282215B2 (en) | 2000-05-08 | 2007-10-16 | The University Of British Columbia | Supports for photosensitizer formulations |
| JP3385468B2 (ja) * | 2000-06-12 | 2003-03-10 | 科学技術振興事業団 | 新規な拡張ポルフィリン及び拡張ポルフィリンの合成法 |
| US20030118937A1 (en) * | 2000-08-23 | 2003-06-26 | Ryousuke Nara | Optical information recording medium |
| JP2005517017A (ja) * | 2002-02-07 | 2005-06-09 | コバレント パートナーズ, エルエルシー | 大環状モジュール組成物 |
| US20040034223A1 (en) * | 2002-02-07 | 2004-02-19 | Covalent Partners, Llc. | Amphiphilic molecular modules and constructs based thereon |
| WO2003067286A2 (en) * | 2002-02-07 | 2003-08-14 | Covalent Partners, Llc | Nanofilm and membrane compositions |
| US6852864B2 (en) | 2002-03-28 | 2005-02-08 | Council Of Scientific And Industrial Research | Process for the synthesis of dipyrromethanes |
| US7375216B2 (en) * | 2002-06-04 | 2008-05-20 | Infacare Pharmaceutical Corporation | Preparation of metal mesoporphyrin compounds |
| AU2003237349B2 (en) | 2002-06-04 | 2010-06-03 | Infacare Pharmaceutical Corporation | Preparation of metal mesoporphyrin halide compounds |
| US7001588B2 (en) * | 2002-09-12 | 2006-02-21 | Cylene Pharmaceuticals | Expanded porphyrin compositions for tumor inhibition |
| US20040106741A1 (en) * | 2002-09-17 | 2004-06-03 | Kriesel Joshua W. | Nanofilm compositions with polymeric components |
| US7332599B2 (en) * | 2003-06-06 | 2008-02-19 | North Carolina State University | Methods and intermediates for the synthesis of dipyrrin-substituted porphyrinic macrocycles |
| WO2005030711A2 (en) * | 2003-08-06 | 2005-04-07 | Covalent Partners Llc | Bridged macrocyclic module compositions |
| US20060222668A1 (en) * | 2005-04-01 | 2006-10-05 | Wellspring Pharmaceutical Corporation | Stannsoporfin compositions, drug products and methods of manufacture |
| WO2007103427A2 (en) * | 2006-03-06 | 2007-09-13 | Wang Xiang H | Medical use of bilirubin and its structural analogues |
| EP2076273A2 (de) * | 2006-10-04 | 2009-07-08 | InfaCare Pharmaceutical Corporation | Behandlung von hyperbilirubinämie bei säuglingen mit niedrigen dosen von stannsoporfin |
| CN101573122B (zh) | 2006-10-04 | 2016-08-03 | 婴儿护理药品公司 | 锡泊芬的高纯度大规模制备 |
| US20120034156A1 (en) * | 2010-08-03 | 2012-02-09 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware | Artificial cells |
| PT2691398T (pt) | 2011-03-30 | 2017-01-02 | Infacare Pharmaceutical Corp | Métodos para sintetizar mesoporfirinas de metal |
| CN103772398A (zh) * | 2014-02-11 | 2014-05-07 | 江苏大学 | 一种催化氧化线性五吡咯合成噻呋啉化合物的方法 |
| CN113121567A (zh) * | 2021-04-22 | 2021-07-16 | 中国科学院大学 | 分子内正交结构的环状三吡咯化合物的合成方法 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5162509A (en) * | 1989-03-06 | 1992-11-10 | Board Of Regents, The University Of Texas System | Process for preparing expanded porphyrins: large porphyrin-like tripyrroledimethine-derived macrocycles |
| US5252720A (en) * | 1989-03-06 | 1993-10-12 | Board Of Regents, The University Of Texas System | Metal complexes of water soluble texaphyrins |
| US4935498A (en) * | 1989-03-06 | 1990-06-19 | Board Of Regents, The University Of Texas System | Expanded porphyrins: large porphyrin-like tripyrroledimethine-derived macrocycles |
| US5159065A (en) * | 1989-12-21 | 1992-10-27 | Board Of Regents, The University Of Texas System | Sapphyrins, derivatives and syntheses |
| DE4027253A1 (de) * | 1990-08-29 | 1992-03-05 | Wacker Chemie Gmbh | Neue arylmethylole, deren herstellung und verwendung |
| DE4305523A1 (de) * | 1993-02-17 | 1994-08-18 | Diagnostikforschung Inst | Meso-Tetraphenylporphyrin-Komplexverbindungen, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Mittel |
| US5756726A (en) * | 1995-06-02 | 1998-05-26 | Pharmacyclics, Inc. | Methods of producing singlet oxygen using compounds having improved functionalization |
| US5599948A (en) * | 1995-11-27 | 1997-02-04 | Sun Company, Inc. | Substituted dipyrromethanes and their preparation |
| US5883246A (en) * | 1996-03-07 | 1999-03-16 | Qlt Phototherapeutics, Inc. | Synthesis of polypyrrolic macrocycles from meso-substituted tripyrrane compounds |
-
1996
- 1996-03-07 US US08/612,215 patent/US5883246A/en not_active Expired - Fee Related
-
1997
- 1997-02-25 AT AT97903180T patent/ATE327994T1/de not_active IP Right Cessation
- 1997-02-25 JP JP53127697A patent/JP2001511112A/ja not_active Ceased
- 1997-02-25 ES ES97903180T patent/ES2267129T3/es not_active Expired - Lifetime
- 1997-02-25 AU AU17625/97A patent/AU1762597A/en not_active Abandoned
- 1997-02-25 DE DE69735992T patent/DE69735992T2/de not_active Expired - Fee Related
- 1997-02-25 EP EP97903180A patent/EP0885228B1/de not_active Expired - Lifetime
- 1997-02-25 WO PCT/CA1997/000133 patent/WO1997032884A1/en not_active Ceased
- 1997-03-14 TW TW086103191A patent/TW502036B/zh not_active IP Right Cessation
-
1998
- 1998-05-19 US US09/080,989 patent/US5919923A/en not_active Expired - Fee Related
-
1999
- 1999-05-17 US US09/313,030 patent/US6022981A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| WO1997032884A1 (en) | 1997-09-12 |
| US6022981A (en) | 2000-02-08 |
| DE69735992D1 (de) | 2006-07-06 |
| AU1762597A (en) | 1997-09-22 |
| US5883246A (en) | 1999-03-16 |
| JP2001511112A (ja) | 2001-08-07 |
| DE69735992T2 (de) | 2007-02-08 |
| TW502036B (en) | 2002-09-11 |
| EP0885228A1 (de) | 1998-12-23 |
| ES2267129T3 (es) | 2007-03-01 |
| US5919923A (en) | 1999-07-06 |
| EP0885228B1 (de) | 2006-05-31 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |