DE69735992D1 - Meso-substituierte tripyrrane derivate, zusammensetzungen und verwendungsmöglichkeiten sowie verfahren zu deren herstellung - Google Patents

Meso-substituierte tripyrrane derivate, zusammensetzungen und verwendungsmöglichkeiten sowie verfahren zu deren herstellung

Info

Publication number
DE69735992D1
DE69735992D1 DE69735992T DE69735992T DE69735992D1 DE 69735992 D1 DE69735992 D1 DE 69735992D1 DE 69735992 T DE69735992 T DE 69735992T DE 69735992 T DE69735992 T DE 69735992T DE 69735992 D1 DE69735992 D1 DE 69735992D1
Authority
DE
Germany
Prior art keywords
group
formula
residue
meso
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69735992T
Other languages
English (en)
Other versions
DE69735992T2 (de
Inventor
Christian Bruckner
W Boyle
David Dolphin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of British Columbia
Original Assignee
University of British Columbia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of British Columbia filed Critical University of British Columbia
Publication of DE69735992D1 publication Critical patent/DE69735992D1/de
Application granted granted Critical
Publication of DE69735992T2 publication Critical patent/DE69735992T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/323—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to the ring nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyrrole Compounds (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Polyoxymethylene Polymers And Polymers With Carbon-To-Carbon Bonds (AREA)
DE69735992T 1996-03-07 1997-02-25 Meso-substituierte tripyrrane derivate, zusammensetzungen und verwendungsmöglichkeiten sowie verfahren zu deren herstellung Expired - Fee Related DE69735992T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US61221596A 1996-03-07 1996-03-07
US612215 1996-03-07
PCT/CA1997/000133 WO1997032884A1 (en) 1996-03-07 1997-02-25 Meso-substituted tripyrrane compounds, compositions, and methods for making and using the same

Publications (2)

Publication Number Publication Date
DE69735992D1 true DE69735992D1 (de) 2006-07-06
DE69735992T2 DE69735992T2 (de) 2007-02-08

Family

ID=24452223

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69735992T Expired - Fee Related DE69735992T2 (de) 1996-03-07 1997-02-25 Meso-substituierte tripyrrane derivate, zusammensetzungen und verwendungsmöglichkeiten sowie verfahren zu deren herstellung

Country Status (9)

Country Link
US (3) US5883246A (de)
EP (1) EP0885228B1 (de)
JP (1) JP2001511112A (de)
AT (1) ATE327994T1 (de)
AU (1) AU1762597A (de)
DE (1) DE69735992T2 (de)
ES (1) ES2267129T3 (de)
TW (1) TW502036B (de)
WO (1) WO1997032884A1 (de)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5883246A (en) * 1996-03-07 1999-03-16 Qlt Phototherapeutics, Inc. Synthesis of polypyrrolic macrocycles from meso-substituted tripyrrane compounds
US20020022032A1 (en) * 1999-04-23 2002-02-21 Curry Patrick Mark Immuno-adjuvant PDT treatment of metastatic tumors
US6316264B1 (en) 1999-12-17 2001-11-13 Bayer Corporation Test strip for the assay of an analyte in a liquid sample
CA2408332C (en) 2000-05-08 2011-02-15 The University Of British Columbia Supports for photosensitizer formulations
US6693093B2 (en) 2000-05-08 2004-02-17 The University Of British Columbia (Ubc) Drug delivery systems for photodynamic therapy
JP3385468B2 (ja) * 2000-06-12 2003-03-10 科学技術振興事業団 新規な拡張ポルフィリン及び拡張ポルフィリンの合成法
EP1316436A1 (de) * 2000-08-23 2003-06-04 Mitsui Chemicals, Inc. Optisches informationsaufzeichnungsmedium
US20040034223A1 (en) * 2002-02-07 2004-02-19 Covalent Partners, Llc. Amphiphilic molecular modules and constructs based thereon
EP1481268A4 (de) * 2002-02-07 2005-06-29 Covalent Partners Llc Nanofilm und membranzusammensetzungen
WO2003066646A2 (en) * 2002-02-07 2003-08-14 Covalent Partners, Llc Macrocyclic module compositions
US6852864B2 (en) 2002-03-28 2005-02-08 Council Of Scientific And Industrial Research Process for the synthesis of dipyrromethanes
US6818763B2 (en) 2002-06-04 2004-11-16 Wellspring Pharmaceutical Corporation Preparation of metal mesoporphyrin halide compounds
US7375216B2 (en) * 2002-06-04 2008-05-20 Infacare Pharmaceutical Corporation Preparation of metal mesoporphyrin compounds
WO2004024091A2 (en) * 2002-09-12 2004-03-25 Cyternex, Inc. Expanded porphyrin compositions for tumor inhibition
US20040106741A1 (en) * 2002-09-17 2004-06-03 Kriesel Joshua W. Nanofilm compositions with polymeric components
US7332599B2 (en) * 2003-06-06 2008-02-19 North Carolina State University Methods and intermediates for the synthesis of dipyrrin-substituted porphyrinic macrocycles
WO2005030711A2 (en) * 2003-08-06 2005-04-07 Covalent Partners Llc Bridged macrocyclic module compositions
US20060222668A1 (en) * 2005-04-01 2006-10-05 Wellspring Pharmaceutical Corporation Stannsoporfin compositions, drug products and methods of manufacture
WO2007103427A2 (en) * 2006-03-06 2007-09-13 Wang Xiang H Medical use of bilirubin and its structural analogues
CN104116745B (zh) 2006-10-04 2018-07-06 婴儿护理药品公司 包含锡泊芬的组合物
MX2009003532A (es) * 2006-10-04 2009-06-26 Infacare Pharmaceutical Corp Tratamiento de hiperbilirrubinemia infantil utilizando bajas dosis de estansoporfina.
US20120034156A1 (en) * 2010-08-03 2012-02-09 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Artificial cells
DK2691398T3 (en) 2011-03-30 2017-01-16 Infacare Pharmaceutical Corp Methods for synthesizing metal mesoporphyrins
CN103772398A (zh) * 2014-02-11 2014-05-07 江苏大学 一种催化氧化线性五吡咯合成噻呋啉化合物的方法
CN113121567A (zh) * 2021-04-22 2021-07-16 中国科学院大学 分子内正交结构的环状三吡咯化合物的合成方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5162509A (en) * 1989-03-06 1992-11-10 Board Of Regents, The University Of Texas System Process for preparing expanded porphyrins: large porphyrin-like tripyrroledimethine-derived macrocycles
US5252720A (en) * 1989-03-06 1993-10-12 Board Of Regents, The University Of Texas System Metal complexes of water soluble texaphyrins
US4935498A (en) * 1989-03-06 1990-06-19 Board Of Regents, The University Of Texas System Expanded porphyrins: large porphyrin-like tripyrroledimethine-derived macrocycles
US5159065A (en) * 1989-12-21 1992-10-27 Board Of Regents, The University Of Texas System Sapphyrins, derivatives and syntheses
DE4027253A1 (de) * 1990-08-29 1992-03-05 Wacker Chemie Gmbh Neue arylmethylole, deren herstellung und verwendung
DE4305523A1 (de) * 1993-02-17 1994-08-18 Diagnostikforschung Inst Meso-Tetraphenylporphyrin-Komplexverbindungen, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Mittel
US5756726A (en) * 1995-06-02 1998-05-26 Pharmacyclics, Inc. Methods of producing singlet oxygen using compounds having improved functionalization
US5599948A (en) * 1995-11-27 1997-02-04 Sun Company, Inc. Substituted dipyrromethanes and their preparation
US5883246A (en) * 1996-03-07 1999-03-16 Qlt Phototherapeutics, Inc. Synthesis of polypyrrolic macrocycles from meso-substituted tripyrrane compounds

Also Published As

Publication number Publication date
EP0885228B1 (de) 2006-05-31
ATE327994T1 (de) 2006-06-15
TW502036B (en) 2002-09-11
WO1997032884A1 (en) 1997-09-12
US5883246A (en) 1999-03-16
EP0885228A1 (de) 1998-12-23
US6022981A (en) 2000-02-08
JP2001511112A (ja) 2001-08-07
US5919923A (en) 1999-07-06
AU1762597A (en) 1997-09-22
ES2267129T3 (es) 2007-03-01
DE69735992T2 (de) 2007-02-08

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee