DE69619230D1 - Oxidatives verfahren zur herstellung von narwedin-derivaten - Google Patents

Oxidatives verfahren zur herstellung von narwedin-derivaten

Info

Publication number
DE69619230D1
DE69619230D1 DE69619230T DE69619230T DE69619230D1 DE 69619230 D1 DE69619230 D1 DE 69619230D1 DE 69619230 T DE69619230 T DE 69619230T DE 69619230 T DE69619230 T DE 69619230T DE 69619230 D1 DE69619230 D1 DE 69619230D1
Authority
DE
Germany
Prior art keywords
narvedine
derivatives
producing
compound
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69619230T
Other languages
English (en)
Other versions
DE69619230T2 (de
Inventor
James Henshilwood
Bernard Johnson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Janssen Pharmaceutica NV
Original Assignee
Janssen Pharmaceutica NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica NV filed Critical Janssen Pharmaceutica NV
Publication of DE69619230D1 publication Critical patent/DE69619230D1/de
Application granted granted Critical
Publication of DE69619230T2 publication Critical patent/DE69619230T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10—Spiro-condensed systems
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
DE69619230T 1995-04-03 1996-04-02 Oxidatives verfahren zur herstellung von narwedin-derivaten Expired - Lifetime DE69619230T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9506843.3A GB9506843D0 (en) 1995-04-03 1995-04-03 Oxidative process and products thereof
PCT/GB1996/000815 WO1996031458A1 (en) 1995-04-03 1996-04-02 Oxidative process for preparing narwedine derivatives

Publications (2)

Publication Number Publication Date
DE69619230D1 true DE69619230D1 (de) 2002-03-21
DE69619230T2 DE69619230T2 (de) 2002-09-19

Family

ID=10772408

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69619230T Expired - Lifetime DE69619230T2 (de) 1995-04-03 1996-04-02 Oxidatives verfahren zur herstellung von narwedin-derivaten

Country Status (12)

Country Link
US (2) US6084094A (de)
EP (1) EP0819112B1 (de)
AT (1) ATE213228T1 (de)
AU (1) AU716794B2 (de)
CA (1) CA2215633C (de)
DE (1) DE69619230T2 (de)
DK (1) DK0819112T3 (de)
ES (1) ES2171661T3 (de)
GB (1) GB9506843D0 (de)
PT (1) PT819112E (de)
WO (1) WO1996031458A1 (de)
ZA (1) ZA962677B (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9506843D0 (en) * 1995-04-03 1995-05-24 Chiroscience Ltd Oxidative process and products thereof
CN1875004B (zh) * 2003-09-26 2010-06-23 台湾神隆股份有限公司 那维啶酰胺衍生物的拆分
CA2551946A1 (en) * 2003-12-31 2005-07-21 Actavis Group Hf Immediate, controlled and sustained release formulations of galantamine
CA2552114A1 (en) * 2003-12-31 2005-07-21 Actavis Group Hf Solid dosage formulations of galantamine
AR054753A1 (es) * 2005-05-03 2007-07-11 Medichem Sa Sintesis y preparaciones de narwedina galantamina y compuestos relacionados
AU2008239730B2 (en) 2007-04-12 2011-10-06 Scinopharm Taiwan, Ltd. Process for making galantamine
DK3114225T3 (da) 2014-03-07 2021-07-26 Dna Genotek Inc Sammensætning og fremgangsmåde til stabilisering af nukleinsyrer i biologiske prøver
CN104592243B (zh) * 2014-12-19 2016-08-24 北京大学 加兰他敏和力克拉敏的不对称合成方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL122665B1 (en) * 1978-11-21 1982-08-31 Edinen Zentar Chim Process for preparing novel dienones of narvedine type and their derivatives
US4290862A (en) * 1979-11-14 1981-09-22 Edinen Centar P Chimia Method for the preparation of narwedine-type enones
DE3856594D1 (de) 1987-05-04 2008-11-27 Bonnie Davis Mittel zur behandlung der alzheimer-krankheit
AT401058B (de) 1994-10-21 1996-06-25 Waldheim Pharmazeutika Gmbh Verfahren zum herstellen von derivaten des 4a,5, 9,10,11,12,-hexahydro-6h-benzofuro(3a,-3,2-ef) (2)benzazepins
GB9506843D0 (en) * 1995-04-03 1995-05-24 Chiroscience Ltd Oxidative process and products thereof
AU709080B2 (en) * 1995-04-06 1999-08-19 Janssen Pharmaceutica N.V. Process for preparing galanthamine derivatives by asymmetric reduction

Also Published As

Publication number Publication date
ATE213228T1 (de) 2002-02-15
ZA962677B (en) 1997-04-03
PT819112E (pt) 2002-07-31
CA2215633A1 (en) 1996-10-10
AU716794B2 (en) 2000-03-09
EP0819112B1 (de) 2002-02-13
ES2171661T3 (es) 2002-09-16
US6084094A (en) 2000-07-04
CA2215633C (en) 2007-07-31
EP0819112A1 (de) 1998-01-21
AU5159596A (en) 1996-10-23
WO1996031458A1 (en) 1996-10-10
GB9506843D0 (en) 1995-05-24
US6271371B1 (en) 2001-08-07
DE69619230T2 (de) 2002-09-19
DK0819112T3 (da) 2002-04-29

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Legal Events

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8364 No opposition during term of opposition