AR003271A1 - Una composicion farmaceutica para el tratamiento del asma inducido por un antigeno y uso de la heparina de peso molecular ultra bajo para la preparación de dicha composicón farmacéutica. - Google Patents

Una composicion farmaceutica para el tratamiento del asma inducido por un antigeno y uso de la heparina de peso molecular ultra bajo para la preparación de dicha composicón farmacéutica.

Info

Publication number
AR003271A1
AR003271A1 ARP960103997A AR10399796A AR003271A1 AR 003271 A1 AR003271 A1 AR 003271A1 AR P960103997 A ARP960103997 A AR P960103997A AR 10399796 A AR10399796 A AR 10399796A AR 003271 A1 AR003271 A1 AR 003271A1
Authority
AR
Argentina
Prior art keywords
pharmaceutical composition
asthma
molecular weight
low molecular
preparation
Prior art date
Application number
ARP960103997A
Other languages
English (en)
Original Assignee
Ivax Research Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ivax Research Inc filed Critical Ivax Research Inc
Publication of AR003271A1 publication Critical patent/AR003271A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/727—Heparin; Heparan
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/12—Aerosols; Foams
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Dispersion Chemistry (AREA)
  • Pulmonology (AREA)
  • Molecular Biology (AREA)
  • Dermatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

Un método para el tratamiento de un paciente afectado de asma inducida por antígeno, que ha sido estimulado con un antígeno inductor de asma, quecomprende la administración intrabronquial al paciente de una composición farmacéutica quecontien e entre 0,05 mg aproximadamente y 1,0 mgaproximadamente de heparinas de peso molecular ultrabajo (en inglés ULMWH) por kilogramo de peso del paciente, en cada dosis; dicha ULMWH tiene un pesomolecular promedio de 3.000 daltons ó menos.
ARP960103997A 1995-08-18 1996-08-15 Una composicion farmaceutica para el tratamiento del asma inducido por un antigeno y uso de la heparina de peso molecular ultra bajo para la preparación de dicha composicón farmacéutica. AR003271A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/516,786 US5690910A (en) 1995-08-18 1995-08-18 Method for treating asthma

Publications (1)

Publication Number Publication Date
AR003271A1 true AR003271A1 (es) 1998-07-08

Family

ID=24057086

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP960103997A AR003271A1 (es) 1995-08-18 1996-08-15 Una composicion farmaceutica para el tratamiento del asma inducido por un antigeno y uso de la heparina de peso molecular ultra bajo para la preparación de dicha composicón farmacéutica.

Country Status (22)

Country Link
US (1) US5690910A (es)
EP (1) EP0844869B1 (es)
JP (1) JP3263723B2 (es)
KR (1) KR100451901B1 (es)
AR (1) AR003271A1 (es)
AT (1) ATE300938T1 (es)
AU (1) AU701691B2 (es)
CA (1) CA2229060A1 (es)
CZ (1) CZ292134B6 (es)
DE (1) DE69635023T2 (es)
DK (1) DK0844869T3 (es)
ES (1) ES2244974T3 (es)
HK (1) HK1007060A1 (es)
HU (1) HUP9901614A3 (es)
IL (1) IL123166A (es)
NZ (2) NZ315275A (es)
PL (1) PL186912B1 (es)
PT (1) PT844869E (es)
SK (1) SK282759B6 (es)
UA (1) UA62919C2 (es)
WO (1) WO1997006783A1 (es)
ZA (1) ZA966838B (es)

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US5980865A (en) * 1995-08-18 1999-11-09 Baker Norton Pharmaceuticals, Inc. Method for treating late phase allergic reactions and inflammatory diseases
US7056504B1 (en) 1998-08-27 2006-06-06 Massachusetts Institute Of Technology Rationally designed heparinases derived from heparinase I and II
SI1124563T1 (en) * 1998-10-30 2005-02-28 Ivax Research, Inc. Methods and compositions for the prevention of tolerance to bronchodilators
US6235725B1 (en) * 1998-10-30 2001-05-22 Baker Norton Pharmaceuticals, Inc. Methods and compositions for the prevention of tolerance to medications
US9006175B2 (en) 1999-06-29 2015-04-14 Mannkind Corporation Potentiation of glucose elimination
ES2527853T3 (es) 2000-03-08 2015-01-30 Massachusetts Institute Of Technology Heparinasa III y sus usos
EP1292314A2 (en) * 2000-05-23 2003-03-19 The Trustees of Columbia University in the City of New York Method for treating respiratory disorders associated with pulmonary elastic fiber injury comprising the use of glycosaminoglycans
US7083937B2 (en) 2000-09-12 2006-08-01 Massachusetts Institute Of Technology Methods and products related to the analysis of polysaccarides
CA2423469A1 (en) * 2000-10-18 2002-04-25 Massachusetts Institute Of Technology Methods and products related to pulmonary delivery of polysaccharides
ES2425392T3 (es) 2002-03-20 2013-10-15 Mannkind Corporation Cartucho para un aparato de inhalación
US20040171819A1 (en) 2002-10-10 2004-09-02 Aventis Pharma S.A. Mixtures of polysaccharides derived from heparin, their preparation and pharmaceutical compositions containing them
US20040152694A1 (en) * 2003-02-04 2004-08-05 Istvan Kurucz Methods and compositions for treating inflammatory disorders of the airways
GB0327723D0 (en) * 2003-09-15 2003-12-31 Vectura Ltd Pharmaceutical compositions
ATE486064T1 (de) 2004-08-20 2010-11-15 Mannkind Corp Katalyse der diketopiperazinsynthese
PL1791542T3 (pl) 2004-08-23 2015-11-30 Mannkind Corp Sole diketopiperazyny do dostarczania leków
AU2005282065B2 (en) * 2004-09-10 2013-02-07 Pharmaorigin Aps Methods for treating local tracheal, bronchial or alveolar bleeding or hemoptysis
AU2006290870B2 (en) 2005-09-14 2013-02-28 Mannkind Corporation Method of drug formulation based on increasing the affinity of active agents for crystalline microparticle surfaces
EP2497484A3 (en) 2006-02-22 2012-11-07 MannKind Corporation A method for improving the pharmaceutic properties of microparticles comprising diketopiperazine and an active agent
US8592393B2 (en) 2007-11-02 2013-11-26 Momenta Pharmaceuticals, Inc. Polysaccharide compositions and methods of use for the treatment and prevention of disorders associated with progenitor cell mobilization
EP2205642B1 (en) * 2007-11-02 2016-01-27 Momenta Pharmaceuticals, Inc. Non-anticoagulant polysaccharide compositions
US8569262B2 (en) * 2007-11-02 2013-10-29 Momenta Pharmaceuticals, Inc. Polysaccharide compositions and methods of use for the treatment and prevention of disorders associated with progenitor cell mobilization
US8485180B2 (en) 2008-06-13 2013-07-16 Mannkind Corporation Dry powder drug delivery system
DK2570147T3 (da) 2008-06-13 2018-01-29 Mannkind Corp Tørpulverinhalator og system til lægemiddelindgivelse
KR101628410B1 (ko) 2008-06-20 2016-06-08 맨카인드 코포레이션 흡입 활동에 관한 실시간 프로파일링을 위한 대화형 장치 및 방법
TWI532497B (zh) 2008-08-11 2016-05-11 曼凱公司 超快起作用胰島素之用途
US8314106B2 (en) 2008-12-29 2012-11-20 Mannkind Corporation Substituted diketopiperazine analogs for use as drug delivery agents
CA2754595C (en) 2009-03-11 2017-06-27 Mannkind Corporation Apparatus, system and method for measuring resistance of an inhaler
US8734845B2 (en) 2009-06-12 2014-05-27 Mannkind Corporation Diketopiperazine microparticles with defined specific surface areas
CA2778698A1 (en) 2009-11-03 2011-05-12 Mannkind Corporation An apparatus and method for simulating inhalation efforts
CA2781923C (en) * 2009-12-03 2018-08-14 Opko Health, Inc. Hypersulfated disaccharide formulations
WO2011130697A2 (en) 2010-04-16 2011-10-20 Momenta Pharmaceuticals, Inc. Tissue targeting
CN103096870B (zh) 2010-06-17 2017-04-19 动量制药公司 调节毛发生长的方法和组合物
RU2531455C2 (ru) 2010-06-21 2014-10-20 Маннкайнд Корпорейшн Системы и способы доставки сухих порошковых лекарств
RU2528093C2 (ru) * 2010-07-21 2014-09-10 Олег Ильич Эпштейн Фармацевтическая композиция и способ лечения острых и хронических заболевания дыхательной системы и синдрома кашля
JP2014500863A (ja) * 2010-10-29 2014-01-16 オプコ ヘルス インコーポレイテッド エラスターゼ関連障害を治療するための高硫酸化二糖
MY180552A (en) 2011-04-01 2020-12-02 Mannkind Corp Blister package for pharmaceutical cartridges
WO2012174472A1 (en) 2011-06-17 2012-12-20 Mannkind Corporation High capacity diketopiperazine microparticles
WO2013063160A1 (en) 2011-10-24 2013-05-02 Mannkind Corporation Methods and compositions for treating pain
CA2878457C (en) 2012-07-12 2021-01-19 Mannkind Corporation Dry powder drug delivery systems and methods
WO2014066856A1 (en) 2012-10-26 2014-05-01 Mannkind Corporation Inhalable influenza vaccine compositions and methods
BR112015023168B1 (pt) 2013-03-15 2021-08-10 Mannkind Corporation Composição de 3,6-bis(n-fumaril-4-aminobutil)-2,5-dicetopiperazina cristalina, método de produção de partículas de 3,6-bis(n-fumaril-4-aminobutil)-2,5-dicetopiperazina e uso de uma composição de dicetopiperazina cristalina
CA2910837A1 (en) 2013-05-28 2014-12-04 Momenta Pharmaceuticals, Inc. Pharmaceutical compositions
CN114848614A (zh) 2013-07-18 2022-08-05 曼金德公司 热稳定性干粉药物组合物和方法
CA2920488C (en) 2013-08-05 2022-04-26 Mannkind Corporation Insufflation apparatus and methods
US10307464B2 (en) 2014-03-28 2019-06-04 Mannkind Corporation Use of ultrarapid acting insulin
US10561806B2 (en) 2014-10-02 2020-02-18 Mannkind Corporation Mouthpiece cover for an inhaler
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ATE134509T1 (de) * 1991-06-10 1996-03-15 Schering Corp Fluorchlorkohlenwasserstoffreie aerosolformulierungen
WO1993019734A1 (en) * 1992-04-02 1993-10-14 Baker Norton Pharmaceuticals, Inc. Method and composition for treating antigen-induced and exercise-induced asthma

Also Published As

Publication number Publication date
HUP9901614A2 (hu) 1999-09-28
PL324970A1 (en) 1998-06-22
AU6694596A (en) 1997-03-12
SK17298A3 (en) 1998-09-09
JPH11511196A (ja) 1999-09-28
DE69635023T2 (de) 2006-05-24
SK282759B6 (sk) 2002-12-03
DE69635023D1 (de) 2005-09-08
WO1997006783A1 (en) 1997-02-27
CA2229060A1 (en) 1997-02-27
EP0844869A4 (en) 2003-04-09
UA62919C2 (en) 2004-01-15
DK0844869T3 (da) 2005-12-12
ATE300938T1 (de) 2005-08-15
CZ48198A3 (cs) 1998-11-11
NZ337996A (en) 2001-04-27
AU701691B2 (en) 1999-02-04
PT844869E (pt) 2005-10-31
EP0844869A1 (en) 1998-06-03
JP3263723B2 (ja) 2002-03-11
KR19990037688A (ko) 1999-05-25
PL186912B1 (pl) 2004-03-31
EP0844869B1 (en) 2005-08-03
US5690910A (en) 1997-11-25
ZA966838B (en) 1997-02-19
MX9801165A (es) 1998-07-31
CZ292134B6 (cs) 2003-08-13
IL123166A0 (en) 1998-09-24
IL123166A (en) 2002-07-25
HUP9901614A3 (en) 2000-04-28
KR100451901B1 (ko) 2005-09-12
ES2244974T3 (es) 2005-12-16
HK1007060A1 (en) 1999-04-01
NZ315275A (en) 2000-01-28

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