HUP9901614A3 - Use of ultra-low molecular weights heparins for preparing pharmaceutical compns. for treting asthma - Google Patents
Use of ultra-low molecular weights heparins for preparing pharmaceutical compns. for treting asthmaInfo
- Publication number
- HUP9901614A3 HUP9901614A3 HU9901614A HUP9901614A HUP9901614A3 HU P9901614 A3 HUP9901614 A3 HU P9901614A3 HU 9901614 A HU9901614 A HU 9901614A HU P9901614 A HUP9901614 A HU P9901614A HU P9901614 A3 HUP9901614 A3 HU P9901614A3
- Authority
- HU
- Hungary
- Prior art keywords
- treting
- heparins
- asthma
- ultra
- low molecular
- Prior art date
Links
- 208000006673 asthma Diseases 0.000 title 1
- 229960002897 heparin Drugs 0.000 title 1
- 229920000669 heparin Polymers 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
- A61K31/727—Heparin; Heparan
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/12—Aerosols; Foams
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dispersion Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Dermatology (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Otolaryngology (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/516,786 US5690910A (en) | 1995-08-18 | 1995-08-18 | Method for treating asthma |
Publications (2)
Publication Number | Publication Date |
---|---|
HUP9901614A2 HUP9901614A2 (hu) | 1999-09-28 |
HUP9901614A3 true HUP9901614A3 (en) | 2000-04-28 |
Family
ID=24057086
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU9901614A HUP9901614A3 (en) | 1995-08-18 | 1996-08-13 | Use of ultra-low molecular weights heparins for preparing pharmaceutical compns. for treting asthma |
Country Status (22)
Country | Link |
---|---|
US (1) | US5690910A (hu) |
EP (1) | EP0844869B1 (hu) |
JP (1) | JP3263723B2 (hu) |
KR (1) | KR100451901B1 (hu) |
AR (1) | AR003271A1 (hu) |
AT (1) | ATE300938T1 (hu) |
AU (1) | AU701691B2 (hu) |
CA (1) | CA2229060A1 (hu) |
CZ (1) | CZ292134B6 (hu) |
DE (1) | DE69635023T2 (hu) |
DK (1) | DK0844869T3 (hu) |
ES (1) | ES2244974T3 (hu) |
HK (1) | HK1007060A1 (hu) |
HU (1) | HUP9901614A3 (hu) |
IL (1) | IL123166A (hu) |
NZ (2) | NZ315275A (hu) |
PL (1) | PL186912B1 (hu) |
PT (1) | PT844869E (hu) |
SK (1) | SK282759B6 (hu) |
UA (1) | UA62919C2 (hu) |
WO (1) | WO1997006783A1 (hu) |
ZA (1) | ZA966838B (hu) |
Families Citing this family (47)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5980865A (en) * | 1995-08-18 | 1999-11-09 | Baker Norton Pharmaceuticals, Inc. | Method for treating late phase allergic reactions and inflammatory diseases |
US7056504B1 (en) | 1998-08-27 | 2006-06-06 | Massachusetts Institute Of Technology | Rationally designed heparinases derived from heparinase I and II |
US6235725B1 (en) * | 1998-10-30 | 2001-05-22 | Baker Norton Pharmaceuticals, Inc. | Methods and compositions for the prevention of tolerance to medications |
EP1462148A3 (en) * | 1998-10-30 | 2010-03-17 | Ivax Research, Inc. | Methods and compositions for the prevention of tolerance to bronchodilators |
US9006175B2 (en) | 1999-06-29 | 2015-04-14 | Mannkind Corporation | Potentiation of glucose elimination |
AU4351201A (en) | 2000-03-08 | 2001-09-17 | Massachusetts Inst Technology | Heparinase iii and uses thereof |
WO2001093846A2 (en) * | 2000-05-23 | 2001-12-13 | The Trustees Of Columbia University In The City Of New York | Method for treating respiratory disorders associated with pulmonary elastic fiber injury comprising the use of clycosaminoglycans |
WO2002023190A2 (en) | 2000-09-12 | 2002-03-21 | Massachusetts Institute Of Technology | Methods and products related to low molecular weight heparin |
AU2002224408B2 (en) * | 2000-10-18 | 2007-08-23 | Massachusetts Institute Of Technology | Methods and products related to pulmonary delivery of polysaccharides |
EP1894591B1 (en) | 2002-03-20 | 2013-06-26 | MannKind Corporation | Cartridge for an inhalation apparatus |
US20040171819A1 (en) | 2002-10-10 | 2004-09-02 | Aventis Pharma S.A. | Mixtures of polysaccharides derived from heparin, their preparation and pharmaceutical compositions containing them |
US20040152694A1 (en) * | 2003-02-04 | 2004-08-05 | Istvan Kurucz | Methods and compositions for treating inflammatory disorders of the airways |
GB0327723D0 (en) * | 2003-09-15 | 2003-12-31 | Vectura Ltd | Pharmaceutical compositions |
PL1786784T3 (pl) | 2004-08-20 | 2011-04-29 | Mannkind Corp | Kataliza syntezy diketopiperazyn |
CN101027057B (zh) | 2004-08-23 | 2017-04-12 | 曼金德公司 | 用于药物输送的二酮哌嗪盐、二酮吗啉盐或二酮二氧杂环己烷盐 |
KR101241434B1 (ko) | 2004-09-10 | 2013-03-12 | 파마오리진 에이피에스 | 국소 기관, 기관지 또는 폐포의 출혈 또는 객혈의 치료방법 |
EP1928423B1 (en) | 2005-09-14 | 2015-12-09 | Mannkind Corporation | Method of drug formulation based on increasing the affinity of active agents for crystalline microparticle surfaces |
ES2647080T3 (es) | 2006-02-22 | 2017-12-19 | Mannkind Corporation | Un método para mejorar las propiedades farmacéuticas de micropartículas que comprenden dicetopiperazina y un agente activo |
WO2009059284A2 (en) * | 2007-11-02 | 2009-05-07 | Momenta Pharmaceuticals, Inc. | Non-anticoagulant polysaccharide compositions |
US8569262B2 (en) * | 2007-11-02 | 2013-10-29 | Momenta Pharmaceuticals, Inc. | Polysaccharide compositions and methods of use for the treatment and prevention of disorders associated with progenitor cell mobilization |
US8592393B2 (en) * | 2007-11-02 | 2013-11-26 | Momenta Pharmaceuticals, Inc. | Polysaccharide compositions and methods of use for the treatment and prevention of disorders associated with progenitor cell mobilization |
US8485180B2 (en) | 2008-06-13 | 2013-07-16 | Mannkind Corporation | Dry powder drug delivery system |
EP2567723B1 (en) | 2008-06-13 | 2021-01-20 | MannKind Corporation | A dry powder inhaler and system for drug delivery |
ES2421385T3 (es) | 2008-06-20 | 2013-09-02 | Mannkind Corp | Aparato interactivo y procedimiento para establecer el perfil, en tiempo real, de esfuerzos de inhalación |
TWI532497B (zh) | 2008-08-11 | 2016-05-11 | 曼凱公司 | 超快起作用胰島素之用途 |
US8314106B2 (en) | 2008-12-29 | 2012-11-20 | Mannkind Corporation | Substituted diketopiperazine analogs for use as drug delivery agents |
EP2676695A3 (en) | 2009-03-11 | 2017-03-01 | MannKind Corporation | Apparatus, system and method for measuring resistance of an inhaler |
KR20210027546A (ko) | 2009-06-12 | 2021-03-10 | 맨카인드 코포레이션 | 한정된 비표면적을 갖는 디케토피페라진 마이크로입자 |
CA2778698A1 (en) | 2009-11-03 | 2011-05-12 | Mannkind Corporation | An apparatus and method for simulating inhalation efforts |
WO2011068721A1 (en) * | 2009-12-03 | 2011-06-09 | Opko Health, Inc. | Hypersulfated disaccharide formulations |
WO2011130697A2 (en) | 2010-04-16 | 2011-10-20 | Momenta Pharmaceuticals, Inc. | Tissue targeting |
CA2795868A1 (en) | 2010-06-17 | 2011-12-22 | Momenta Pharmaceuticals, Inc. | Methods and compositions for modulating hair growth |
KR20130117755A (ko) | 2010-06-21 | 2013-10-28 | 맨카인드 코포레이션 | 건조 분말 약물 운반 시스템 및 방법 |
RU2528093C2 (ru) * | 2010-07-21 | 2014-09-10 | Олег Ильич Эпштейн | Фармацевтическая композиция и способ лечения острых и хронических заболевания дыхательной системы и синдрома кашля |
CN103269585B (zh) * | 2010-10-29 | 2016-12-21 | Opko健康公司 | 治疗弹性蛋白酶相关病症的超硫酸化双糖 |
EP2694402B1 (en) | 2011-04-01 | 2017-03-22 | MannKind Corporation | Blister package for pharmaceutical cartridges |
WO2012174472A1 (en) | 2011-06-17 | 2012-12-20 | Mannkind Corporation | High capacity diketopiperazine microparticles |
US9233159B2 (en) | 2011-10-24 | 2016-01-12 | Mannkind Corporation | Methods and compositions for treating pain |
AU2013289957B2 (en) | 2012-07-12 | 2017-02-23 | Mannkind Corporation | Dry powder drug delivery systems and methods |
EP2911690A1 (en) | 2012-10-26 | 2015-09-02 | MannKind Corporation | Inhalable influenza vaccine compositions and methods |
MX369136B (es) | 2013-03-15 | 2019-10-30 | Mannkind Corp | Composiciones de dicetopiperazina microcristalina y metodos. |
JP2016520613A (ja) | 2013-05-28 | 2016-07-14 | モメンタ ファーマシューティカルズ インコーポレイテッド | 薬学的組成物 |
KR102465025B1 (ko) | 2013-07-18 | 2022-11-09 | 맨카인드 코포레이션 | 열-안정성 건조 분말 약제학적 조성물 및 방법 |
US11446127B2 (en) | 2013-08-05 | 2022-09-20 | Mannkind Corporation | Insufflation apparatus and methods |
US10307464B2 (en) | 2014-03-28 | 2019-06-04 | Mannkind Corporation | Use of ultrarapid acting insulin |
US10561806B2 (en) | 2014-10-02 | 2020-02-18 | Mannkind Corporation | Mouthpiece cover for an inhaler |
EP3500583A1 (en) | 2016-08-16 | 2019-06-26 | OPKO Pharmaceuticals, LLC | Pure heptasulfated disaccharides having improved oral bioavailability |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5474759A (en) * | 1991-06-10 | 1995-12-12 | Schering Corporation | Non-chlorofluorocarbon aerosol formulations |
WO1993019734A1 (en) * | 1992-04-02 | 1993-10-14 | Baker Norton Pharmaceuticals, Inc. | Method and composition for treating antigen-induced and exercise-induced asthma |
-
1995
- 1995-08-18 US US08/516,786 patent/US5690910A/en not_active Expired - Fee Related
-
1996
- 1996-08-13 HU HU9901614A patent/HUP9901614A3/hu unknown
- 1996-08-13 PL PL96324970A patent/PL186912B1/pl unknown
- 1996-08-13 ES ES96926952T patent/ES2244974T3/es not_active Expired - Lifetime
- 1996-08-13 PT PT96926952T patent/PT844869E/pt unknown
- 1996-08-13 NZ NZ315275A patent/NZ315275A/xx not_active IP Right Cessation
- 1996-08-13 IL IL12316696A patent/IL123166A/en not_active IP Right Cessation
- 1996-08-13 DK DK96926952T patent/DK0844869T3/da active
- 1996-08-13 UA UA98020876A patent/UA62919C2/uk unknown
- 1996-08-13 DE DE69635023T patent/DE69635023T2/de not_active Expired - Lifetime
- 1996-08-13 AU AU66945/96A patent/AU701691B2/en not_active Expired
- 1996-08-13 ZA ZA9606838A patent/ZA966838B/xx unknown
- 1996-08-13 CA CA002229060A patent/CA2229060A1/en not_active Abandoned
- 1996-08-13 CZ CZ1998481A patent/CZ292134B6/cs not_active IP Right Cessation
- 1996-08-13 WO PCT/US1996/013133 patent/WO1997006783A1/en active IP Right Grant
- 1996-08-13 EP EP96926952A patent/EP0844869B1/en not_active Expired - Lifetime
- 1996-08-13 KR KR10-1998-0701167A patent/KR100451901B1/ko not_active IP Right Cessation
- 1996-08-13 SK SK172-98A patent/SK282759B6/sk not_active IP Right Cessation
- 1996-08-13 JP JP50942897A patent/JP3263723B2/ja not_active Expired - Lifetime
- 1996-08-13 AT AT96926952T patent/ATE300938T1/de active
- 1996-08-15 AR ARP960103997A patent/AR003271A1/es not_active Application Discontinuation
-
1998
- 1998-06-24 HK HK98106409A patent/HK1007060A1/xx not_active IP Right Cessation
-
1999
- 1999-09-23 NZ NZ337996A patent/NZ337996A/en not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
AR003271A1 (es) | 1998-07-08 |
UA62919C2 (en) | 2004-01-15 |
KR19990037688A (ko) | 1999-05-25 |
ES2244974T3 (es) | 2005-12-16 |
DE69635023T2 (de) | 2006-05-24 |
NZ315275A (en) | 2000-01-28 |
PL324970A1 (en) | 1998-06-22 |
AU6694596A (en) | 1997-03-12 |
US5690910A (en) | 1997-11-25 |
IL123166A (en) | 2002-07-25 |
HK1007060A1 (en) | 1999-04-01 |
DK0844869T3 (da) | 2005-12-12 |
JP3263723B2 (ja) | 2002-03-11 |
PL186912B1 (pl) | 2004-03-31 |
HUP9901614A2 (hu) | 1999-09-28 |
JPH11511196A (ja) | 1999-09-28 |
ZA966838B (en) | 1997-02-19 |
ATE300938T1 (de) | 2005-08-15 |
CZ48198A3 (cs) | 1998-11-11 |
WO1997006783A1 (en) | 1997-02-27 |
CZ292134B6 (cs) | 2003-08-13 |
AU701691B2 (en) | 1999-02-04 |
SK282759B6 (sk) | 2002-12-03 |
PT844869E (pt) | 2005-10-31 |
EP0844869A1 (en) | 1998-06-03 |
EP0844869A4 (en) | 2003-04-09 |
DE69635023D1 (de) | 2005-09-08 |
IL123166A0 (en) | 1998-09-24 |
KR100451901B1 (ko) | 2005-09-12 |
EP0844869B1 (en) | 2005-08-03 |
CA2229060A1 (en) | 1997-02-27 |
SK17298A3 (en) | 1998-09-09 |
MX9801165A (es) | 1998-07-31 |
NZ337996A (en) | 2001-04-27 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
HC9A | Change of name, address |
Owner name: IVAX RESEARCH, INC., US Free format text: FORMER OWNER(S): BAKER NORTON PHARMACEUTICALS, INC., US |