HUP9901614A3 - Use of ultra-low molecular weights heparins for preparing pharmaceutical compns. for treting asthma - Google Patents

Use of ultra-low molecular weights heparins for preparing pharmaceutical compns. for treting asthma

Info

Publication number
HUP9901614A3
HUP9901614A3 HU9901614A HUP9901614A HUP9901614A3 HU P9901614 A3 HUP9901614 A3 HU P9901614A3 HU 9901614 A HU9901614 A HU 9901614A HU P9901614 A HUP9901614 A HU P9901614A HU P9901614 A3 HUP9901614 A3 HU P9901614A3
Authority
HU
Hungary
Prior art keywords
treting
heparins
asthma
ultra
low molecular
Prior art date
Application number
HU9901614A
Other languages
English (en)
Original Assignee
Baker Norton Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Baker Norton Pharma filed Critical Baker Norton Pharma
Publication of HUP9901614A2 publication Critical patent/HUP9901614A2/hu
Publication of HUP9901614A3 publication Critical patent/HUP9901614A3/hu

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/727Heparin; Heparan
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0078Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/12Aerosols; Foams
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dispersion Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Dermatology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Otolaryngology (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
HU9901614A 1995-08-18 1996-08-13 Use of ultra-low molecular weights heparins for preparing pharmaceutical compns. for treting asthma HUP9901614A3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/516,786 US5690910A (en) 1995-08-18 1995-08-18 Method for treating asthma

Publications (2)

Publication Number Publication Date
HUP9901614A2 HUP9901614A2 (hu) 1999-09-28
HUP9901614A3 true HUP9901614A3 (en) 2000-04-28

Family

ID=24057086

Family Applications (1)

Application Number Title Priority Date Filing Date
HU9901614A HUP9901614A3 (en) 1995-08-18 1996-08-13 Use of ultra-low molecular weights heparins for preparing pharmaceutical compns. for treting asthma

Country Status (22)

Country Link
US (1) US5690910A (hu)
EP (1) EP0844869B1 (hu)
JP (1) JP3263723B2 (hu)
KR (1) KR100451901B1 (hu)
AR (1) AR003271A1 (hu)
AT (1) ATE300938T1 (hu)
AU (1) AU701691B2 (hu)
CA (1) CA2229060A1 (hu)
CZ (1) CZ292134B6 (hu)
DE (1) DE69635023T2 (hu)
DK (1) DK0844869T3 (hu)
ES (1) ES2244974T3 (hu)
HK (1) HK1007060A1 (hu)
HU (1) HUP9901614A3 (hu)
IL (1) IL123166A (hu)
NZ (2) NZ315275A (hu)
PL (1) PL186912B1 (hu)
PT (1) PT844869E (hu)
SK (1) SK282759B6 (hu)
UA (1) UA62919C2 (hu)
WO (1) WO1997006783A1 (hu)
ZA (1) ZA966838B (hu)

Families Citing this family (47)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5980865A (en) * 1995-08-18 1999-11-09 Baker Norton Pharmaceuticals, Inc. Method for treating late phase allergic reactions and inflammatory diseases
US7056504B1 (en) 1998-08-27 2006-06-06 Massachusetts Institute Of Technology Rationally designed heparinases derived from heparinase I and II
US6235725B1 (en) * 1998-10-30 2001-05-22 Baker Norton Pharmaceuticals, Inc. Methods and compositions for the prevention of tolerance to medications
EP1462148A3 (en) * 1998-10-30 2010-03-17 Ivax Research, Inc. Methods and compositions for the prevention of tolerance to bronchodilators
US9006175B2 (en) 1999-06-29 2015-04-14 Mannkind Corporation Potentiation of glucose elimination
AU4351201A (en) 2000-03-08 2001-09-17 Massachusetts Inst Technology Heparinase iii and uses thereof
WO2001093846A2 (en) * 2000-05-23 2001-12-13 The Trustees Of Columbia University In The City Of New York Method for treating respiratory disorders associated with pulmonary elastic fiber injury comprising the use of clycosaminoglycans
WO2002023190A2 (en) 2000-09-12 2002-03-21 Massachusetts Institute Of Technology Methods and products related to low molecular weight heparin
AU2002224408B2 (en) * 2000-10-18 2007-08-23 Massachusetts Institute Of Technology Methods and products related to pulmonary delivery of polysaccharides
EP1894591B1 (en) 2002-03-20 2013-06-26 MannKind Corporation Cartridge for an inhalation apparatus
US20040171819A1 (en) 2002-10-10 2004-09-02 Aventis Pharma S.A. Mixtures of polysaccharides derived from heparin, their preparation and pharmaceutical compositions containing them
US20040152694A1 (en) * 2003-02-04 2004-08-05 Istvan Kurucz Methods and compositions for treating inflammatory disorders of the airways
GB0327723D0 (en) * 2003-09-15 2003-12-31 Vectura Ltd Pharmaceutical compositions
PL1786784T3 (pl) 2004-08-20 2011-04-29 Mannkind Corp Kataliza syntezy diketopiperazyn
CN101027057B (zh) 2004-08-23 2017-04-12 曼金德公司 用于药物输送的二酮哌嗪盐、二酮吗啉盐或二酮二氧杂环己烷盐
KR101241434B1 (ko) 2004-09-10 2013-03-12 파마오리진 에이피에스 국소 기관, 기관지 또는 폐포의 출혈 또는 객혈의 치료방법
EP1928423B1 (en) 2005-09-14 2015-12-09 Mannkind Corporation Method of drug formulation based on increasing the affinity of active agents for crystalline microparticle surfaces
ES2647080T3 (es) 2006-02-22 2017-12-19 Mannkind Corporation Un método para mejorar las propiedades farmacéuticas de micropartículas que comprenden dicetopiperazina y un agente activo
WO2009059284A2 (en) * 2007-11-02 2009-05-07 Momenta Pharmaceuticals, Inc. Non-anticoagulant polysaccharide compositions
US8569262B2 (en) * 2007-11-02 2013-10-29 Momenta Pharmaceuticals, Inc. Polysaccharide compositions and methods of use for the treatment and prevention of disorders associated with progenitor cell mobilization
US8592393B2 (en) * 2007-11-02 2013-11-26 Momenta Pharmaceuticals, Inc. Polysaccharide compositions and methods of use for the treatment and prevention of disorders associated with progenitor cell mobilization
US8485180B2 (en) 2008-06-13 2013-07-16 Mannkind Corporation Dry powder drug delivery system
EP2567723B1 (en) 2008-06-13 2021-01-20 MannKind Corporation A dry powder inhaler and system for drug delivery
ES2421385T3 (es) 2008-06-20 2013-09-02 Mannkind Corp Aparato interactivo y procedimiento para establecer el perfil, en tiempo real, de esfuerzos de inhalación
TWI532497B (zh) 2008-08-11 2016-05-11 曼凱公司 超快起作用胰島素之用途
US8314106B2 (en) 2008-12-29 2012-11-20 Mannkind Corporation Substituted diketopiperazine analogs for use as drug delivery agents
EP2676695A3 (en) 2009-03-11 2017-03-01 MannKind Corporation Apparatus, system and method for measuring resistance of an inhaler
KR20210027546A (ko) 2009-06-12 2021-03-10 맨카인드 코포레이션 한정된 비표면적을 갖는 디케토피페라진 마이크로입자
CA2778698A1 (en) 2009-11-03 2011-05-12 Mannkind Corporation An apparatus and method for simulating inhalation efforts
WO2011068721A1 (en) * 2009-12-03 2011-06-09 Opko Health, Inc. Hypersulfated disaccharide formulations
WO2011130697A2 (en) 2010-04-16 2011-10-20 Momenta Pharmaceuticals, Inc. Tissue targeting
CA2795868A1 (en) 2010-06-17 2011-12-22 Momenta Pharmaceuticals, Inc. Methods and compositions for modulating hair growth
KR20130117755A (ko) 2010-06-21 2013-10-28 맨카인드 코포레이션 건조 분말 약물 운반 시스템 및 방법
RU2528093C2 (ru) * 2010-07-21 2014-09-10 Олег Ильич Эпштейн Фармацевтическая композиция и способ лечения острых и хронических заболевания дыхательной системы и синдрома кашля
CN103269585B (zh) * 2010-10-29 2016-12-21 Opko健康公司 治疗弹性蛋白酶相关病症的超硫酸化双糖
EP2694402B1 (en) 2011-04-01 2017-03-22 MannKind Corporation Blister package for pharmaceutical cartridges
WO2012174472A1 (en) 2011-06-17 2012-12-20 Mannkind Corporation High capacity diketopiperazine microparticles
US9233159B2 (en) 2011-10-24 2016-01-12 Mannkind Corporation Methods and compositions for treating pain
AU2013289957B2 (en) 2012-07-12 2017-02-23 Mannkind Corporation Dry powder drug delivery systems and methods
EP2911690A1 (en) 2012-10-26 2015-09-02 MannKind Corporation Inhalable influenza vaccine compositions and methods
MX369136B (es) 2013-03-15 2019-10-30 Mannkind Corp Composiciones de dicetopiperazina microcristalina y metodos.
JP2016520613A (ja) 2013-05-28 2016-07-14 モメンタ ファーマシューティカルズ インコーポレイテッド 薬学的組成物
KR102465025B1 (ko) 2013-07-18 2022-11-09 맨카인드 코포레이션 열-안정성 건조 분말 약제학적 조성물 및 방법
US11446127B2 (en) 2013-08-05 2022-09-20 Mannkind Corporation Insufflation apparatus and methods
US10307464B2 (en) 2014-03-28 2019-06-04 Mannkind Corporation Use of ultrarapid acting insulin
US10561806B2 (en) 2014-10-02 2020-02-18 Mannkind Corporation Mouthpiece cover for an inhaler
EP3500583A1 (en) 2016-08-16 2019-06-26 OPKO Pharmaceuticals, LLC Pure heptasulfated disaccharides having improved oral bioavailability

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5474759A (en) * 1991-06-10 1995-12-12 Schering Corporation Non-chlorofluorocarbon aerosol formulations
WO1993019734A1 (en) * 1992-04-02 1993-10-14 Baker Norton Pharmaceuticals, Inc. Method and composition for treating antigen-induced and exercise-induced asthma

Also Published As

Publication number Publication date
AR003271A1 (es) 1998-07-08
UA62919C2 (en) 2004-01-15
KR19990037688A (ko) 1999-05-25
ES2244974T3 (es) 2005-12-16
DE69635023T2 (de) 2006-05-24
NZ315275A (en) 2000-01-28
PL324970A1 (en) 1998-06-22
AU6694596A (en) 1997-03-12
US5690910A (en) 1997-11-25
IL123166A (en) 2002-07-25
HK1007060A1 (en) 1999-04-01
DK0844869T3 (da) 2005-12-12
JP3263723B2 (ja) 2002-03-11
PL186912B1 (pl) 2004-03-31
HUP9901614A2 (hu) 1999-09-28
JPH11511196A (ja) 1999-09-28
ZA966838B (en) 1997-02-19
ATE300938T1 (de) 2005-08-15
CZ48198A3 (cs) 1998-11-11
WO1997006783A1 (en) 1997-02-27
CZ292134B6 (cs) 2003-08-13
AU701691B2 (en) 1999-02-04
SK282759B6 (sk) 2002-12-03
PT844869E (pt) 2005-10-31
EP0844869A1 (en) 1998-06-03
EP0844869A4 (en) 2003-04-09
DE69635023D1 (de) 2005-09-08
IL123166A0 (en) 1998-09-24
KR100451901B1 (ko) 2005-09-12
EP0844869B1 (en) 2005-08-03
CA2229060A1 (en) 1997-02-27
SK17298A3 (en) 1998-09-09
MX9801165A (es) 1998-07-31
NZ337996A (en) 2001-04-27

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Legal Events

Date Code Title Description
HC9A Change of name, address

Owner name: IVAX RESEARCH, INC., US

Free format text: FORMER OWNER(S): BAKER NORTON PHARMACEUTICALS, INC., US