AP770A - Method for diagnosing schizophrenia. - Google Patents

Method for diagnosing schizophrenia. Download PDF

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Publication number
AP770A
AP770A APAP/P/1997/001126A AP9701126A AP770A AP 770 A AP770 A AP 770A AP 9701126 A AP9701126 A AP 9701126A AP 770 A AP770 A AP 770A
Authority
AP
ARIPO
Prior art keywords
allele
schizophrenia
dna
primers
microsatellite
Prior art date
Application number
APAP/P/1997/001126A
Other languages
English (en)
Other versions
AP9701126A0 (en
Inventor
Claudine Laurent
Jacques Mallet
Rolando Meloni
Original Assignee
Rhone Poulenc Rorer Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Rorer Sa filed Critical Rhone Poulenc Rorer Sa
Publication of AP9701126A0 publication Critical patent/AP9701126A0/xx
Application granted granted Critical
Publication of AP770A publication Critical patent/AP770A/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C07H21/04—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • C12P19/28—N-glycosides
    • C12P19/30—Nucleotides
    • C12P19/34—Polynucleotides, e.g. nucleic acids, oligoribonucleotides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y10T436/142222—Hetero-O [e.g., ascorbic acid, etc.]
    • Y10T436/143333—Saccharide [e.g., DNA, etc.]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
APAP/P/1997/001126A 1995-05-03 1996-04-29 Method for diagnosing schizophrenia. AP770A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9505264A FR2733766B1 (fr) 1995-05-03 1995-05-03 Methode de diagnostic de la schizophrenie
PCT/FR1996/000650 WO1996034980A1 (fr) 1995-05-03 1996-04-29 Methode de diagnostic de la schizophrenie

Publications (2)

Publication Number Publication Date
AP9701126A0 AP9701126A0 (en) 1997-10-31
AP770A true AP770A (en) 1999-10-06

Family

ID=9478648

Family Applications (1)

Application Number Title Priority Date Filing Date
APAP/P/1997/001126A AP770A (en) 1995-05-03 1996-04-29 Method for diagnosing schizophrenia.

Country Status (29)

Country Link
US (1) US6210879B1 (no)
EP (1) EP0826068B1 (no)
JP (1) JPH11504809A (no)
KR (1) KR19990008221A (no)
CN (1) CN1125881C (no)
AP (1) AP770A (no)
AT (1) ATE193559T1 (no)
AU (1) AU715264B2 (no)
BG (1) BG63017B1 (no)
BR (1) BR9608432A (no)
CA (1) CA2217332A1 (no)
CZ (1) CZ291234B6 (no)
DE (1) DE69608682T2 (no)
DK (1) DK0826068T3 (no)
EA (1) EA001037B1 (no)
ES (1) ES2148760T3 (no)
FR (1) FR2733766B1 (no)
GR (1) GR3033592T3 (no)
HU (1) HUP9802918A3 (no)
NO (1) NO974974L (no)
NZ (1) NZ308132A (no)
OA (1) OA10534A (no)
PL (1) PL183819B1 (no)
PT (1) PT826068E (no)
RO (1) RO116731B1 (no)
SI (1) SI0826068T1 (no)
SK (1) SK282119B6 (no)
UA (1) UA49827C2 (no)
WO (1) WO1996034980A1 (no)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6566065B1 (en) * 1994-05-26 2003-05-20 Mcgill University Method of diagnosing schizophrenia by detecting a mutation in the (MTHFR) gene
US6395524B2 (en) 1996-11-27 2002-05-28 University Of Washington Thermostable polymerases having altered fidelity and method of identifying and using same
US7166462B2 (en) 2000-08-24 2007-01-23 Vanderbult University Methods and systems for facilitating the diagnosis and treatment of schizophrenia
US20020106794A1 (en) * 2000-08-30 2002-08-08 Lorraine Iacovitti Tyrosine hydroxylase 5' control elements and uses thereof
US20070072233A1 (en) * 2001-05-01 2007-03-29 Levitt Pat R Methods and systems for facilitating the diagnosis and treatment of schizophrenia
DE10141464A1 (de) * 2001-08-23 2004-03-04 Genprofile Ag I.Ins. Sequenzvarianten des für neuropsychiatrische Krankheiten verantwortlichen Gens 22444 und deren Verwendung
US6764824B2 (en) * 2002-03-21 2004-07-20 Council Of Scientific And Industrial Research Primers for screening schizophrenia and a method thereof
AU2003231562A1 (en) * 2003-05-19 2004-12-03 Institute Of Mental Health, Peking University Detecting method of the schizophrenia susceptible gene and use
US8709762B2 (en) 2010-03-02 2014-04-29 Bio-Rad Laboratories, Inc. System for hot-start amplification via a multiple emulsion
WO2011120020A1 (en) 2010-03-25 2011-09-29 Quantalife, Inc. Droplet transport system for detection
US9764322B2 (en) 2008-09-23 2017-09-19 Bio-Rad Laboratories, Inc. System for generating droplets with pressure monitoring
US9417190B2 (en) 2008-09-23 2016-08-16 Bio-Rad Laboratories, Inc. Calibrations and controls for droplet-based assays
US9492797B2 (en) 2008-09-23 2016-11-15 Bio-Rad Laboratories, Inc. System for detection of spaced droplets
US8633015B2 (en) * 2008-09-23 2014-01-21 Bio-Rad Laboratories, Inc. Flow-based thermocycling system with thermoelectric cooler
US11130128B2 (en) 2008-09-23 2021-09-28 Bio-Rad Laboratories, Inc. Detection method for a target nucleic acid
US9132394B2 (en) 2008-09-23 2015-09-15 Bio-Rad Laboratories, Inc. System for detection of spaced droplets
US9598725B2 (en) * 2010-03-02 2017-03-21 Bio-Rad Laboratories, Inc. Emulsion chemistry for encapsulated droplets
US10512910B2 (en) 2008-09-23 2019-12-24 Bio-Rad Laboratories, Inc. Droplet-based analysis method
US8951939B2 (en) 2011-07-12 2015-02-10 Bio-Rad Laboratories, Inc. Digital assays with multiplexed detection of two or more targets in the same optical channel
US9156010B2 (en) 2008-09-23 2015-10-13 Bio-Rad Laboratories, Inc. Droplet-based assay system
US9399215B2 (en) 2012-04-13 2016-07-26 Bio-Rad Laboratories, Inc. Sample holder with a well having a wicking promoter
EP2940153B1 (en) 2009-09-02 2020-05-13 Bio-Rad Laboratories, Inc. System for mixing fluids by coalescence of multiple emulsions
CA2767113A1 (en) 2010-03-25 2011-09-29 Bio-Rad Laboratories, Inc. Detection system for droplet-based assays
EP2550528B1 (en) 2010-03-25 2019-09-11 Bio-Rad Laboratories, Inc. Droplet generation for droplet-based assays
JP5922139B2 (ja) 2010-11-01 2016-05-24 バイオ−ラッド・ラボラトリーズ・インコーポレーテッド エマルジョンを形成するためのシステム
CN103534360A (zh) 2011-03-18 2014-01-22 伯乐生命医学产品有限公司 借助对信号的组合使用进行的多重数字分析
EP2702175B1 (en) 2011-04-25 2018-08-08 Bio-Rad Laboratories, Inc. Methods and compositions for nucleic acid analysis
EP2737089B1 (en) 2011-07-29 2017-09-06 Bio-rad Laboratories, Inc. Library characterization by digital assay
CN107677831A (zh) * 2017-06-28 2018-02-09 深圳市龙岗中心医院 测定用于评估精神分裂症病人的诊断标志物的方法

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994003640A1 (en) * 1992-07-31 1994-02-17 Government Of The United States As Represented By Secretary Department Of Health And Human Services Eleven highly informative microsatellite repeat polymorphic dna markers

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994003640A1 (en) * 1992-07-31 1994-02-17 Government Of The United States As Represented By Secretary Department Of Health And Human Services Eleven highly informative microsatellite repeat polymorphic dna markers

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
THE LANCET, vol. 345, April 1995, page 932 XP002012401 MELONI, R. ET AL.: "Association of maniac-depressive illness with typrosine hydroxylase microsatellite marker" *

Also Published As

Publication number Publication date
ES2148760T3 (es) 2000-10-16
AP9701126A0 (en) 1997-10-31
DK0826068T3 (da) 2000-08-28
EA001037B1 (ru) 2000-08-28
SK282119B6 (sk) 2001-11-06
CN1125881C (zh) 2003-10-29
HUP9802918A2 (hu) 1999-03-29
BG63017B1 (bg) 2001-01-31
HUP9802918A3 (en) 2001-01-29
EA199700355A1 (ru) 1998-08-27
PL183819B1 (pl) 2002-07-31
JPH11504809A (ja) 1999-05-11
NO974974D0 (no) 1997-10-28
KR19990008221A (ko) 1999-01-25
OA10534A (fr) 2002-04-29
PL323178A1 (en) 1998-03-16
PT826068E (pt) 2000-12-29
DE69608682D1 (de) 2000-07-06
BR9608432A (pt) 1999-03-02
WO1996034980A1 (fr) 1996-11-07
ATE193559T1 (de) 2000-06-15
CZ346797A3 (cs) 1998-01-14
AU5767896A (en) 1996-11-21
AU715264B2 (en) 2000-01-20
FR2733766A1 (fr) 1996-11-08
CN1183122A (zh) 1998-05-27
GR3033592T3 (en) 2000-09-29
UA49827C2 (uk) 2002-10-15
CZ291234B6 (cs) 2003-01-15
EP0826068A1 (fr) 1998-03-04
DE69608682T2 (de) 2000-10-26
NZ308132A (en) 1999-10-28
RO116731B1 (ro) 2001-05-30
BG102016A (en) 1998-11-30
FR2733766B1 (fr) 1997-06-06
SK147997A3 (en) 1998-05-06
SI0826068T1 (en) 2000-10-31
CA2217332A1 (fr) 1996-11-07
US6210879B1 (en) 2001-04-03
NO974974L (no) 1997-10-28
EP0826068B1 (fr) 2000-05-31

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