AP638A - Pharmaceutical formulations comprising polythiourea and method of use thereof. - Google Patents

Pharmaceutical formulations comprising polythiourea and method of use thereof. Download PDF

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Publication number
AP638A
AP638A APAP/P/1996/000842A AP9600842A AP638A AP 638 A AP638 A AP 638A AP 9600842 A AP9600842 A AP 9600842A AP 638 A AP638 A AP 638A
Authority
AP
ARIPO
Prior art keywords
oligomer
oligomers
polythiourea
hiv
pharmaceutical formulation
Prior art date
Application number
APAP/P/1996/000842A
Other languages
English (en)
Other versions
AP9600842A0 (en
Inventor
Michael J Mullins
William Arthur Fordyce
William Jack Krupper
Norton P Peet
Allan D Cardin
Original Assignee
Dow Chemical Co
Merrell Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dow Chemical Co, Merrell Pharma Inc filed Critical Dow Chemical Co
Publication of AP9600842A0 publication Critical patent/AP9600842A0/xx
Application granted granted Critical
Publication of AP638A publication Critical patent/AP638A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C335/00—Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C335/04—Derivatives of thiourea
    • C07C335/16—Derivatives of thiourea having nitrogen atoms of thiourea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C335/00—Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C335/04—Derivatives of thiourea
    • C07C335/16—Derivatives of thiourea having nitrogen atoms of thiourea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C335/20—Derivatives of thiourea having nitrogen atoms of thiourea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by nitrogen atoms, not being part of nitro or nitroso groups

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
APAP/P/1996/000842A 1994-01-03 1995-01-03 Pharmaceutical formulations comprising polythiourea and method of use thereof. AP638A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US17658694A 1994-01-03 1994-01-03

Publications (2)

Publication Number Publication Date
AP9600842A0 AP9600842A0 (en) 1996-07-31
AP638A true AP638A (en) 1998-04-14

Family

ID=22644965

Family Applications (1)

Application Number Title Priority Date Filing Date
APAP/P/1996/000842A AP638A (en) 1994-01-03 1995-01-03 Pharmaceutical formulations comprising polythiourea and method of use thereof.

Country Status (23)

Country Link
US (1) US6086864A (el)
EP (1) EP0738261B1 (el)
KR (1) KR100362343B1 (el)
CN (1) CN1070180C (el)
AP (1) AP638A (el)
AT (1) ATE178595T1 (el)
AU (1) AU693853B2 (el)
CA (1) CA2179988C (el)
CZ (1) CZ197996A3 (el)
DE (1) DE69508913T2 (el)
DK (1) DK0738261T3 (el)
ES (1) ES2133734T3 (el)
FI (1) FI962725A0 (el)
GR (1) GR3030521T3 (el)
HU (1) HUT74694A (el)
IL (1) IL112174A (el)
MX (1) MX9602542A (el)
NO (1) NO306613B1 (el)
NZ (1) NZ279587A (el)
OA (1) OA10367A (el)
TW (1) TW303377B (el)
WO (1) WO1995018791A1 (el)
ZA (1) ZA9410408B (el)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6186659B1 (en) * 1998-08-21 2001-02-13 Agilent Technologies Inc. Apparatus and method for mixing a film of fluid
CN105582020B (zh) * 2014-10-21 2019-04-16 浙江大学 一种线形聚硫脲和超支化聚硫脲在制备抗肿瘤药物及抗病毒或抗菌药物中的应用
CN107236128A (zh) * 2017-06-21 2017-10-10 华南理工大学 一种异腈、硫和胺的多组分聚合制备聚硫脲的方法及该聚硫脲的应用

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2868834A (en) * 1955-02-01 1959-01-13 Ciba Pharm Prod Inc Manufacture of new polythioureas
WO1992000749A1 (en) * 1990-07-09 1992-01-23 Merrell Dow Pharmaceuticals Inc. Anti-herpes virus and cytomegalovirus oligomers
WO1993014146A1 (en) * 1992-01-09 1993-07-22 The Dow Chemical Company Narrow poly- and mono-dispersed anionic oligomers, and their uses, formulations and process

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE544868A (el) *
GB781479A (en) * 1953-08-27 1957-08-21 Ciba Ltd New polyureas and process for making them
US2833744A (en) * 1953-08-27 1958-05-06 Ciba Pharm Prod Inc Polyureas and process of preparing same
US3164571A (en) * 1959-12-31 1965-01-05 Union Carbide Corp Polyureas from n-phenyl, phenylene biscarbamyl halide and a diamine
US3528949A (en) * 1968-05-07 1970-09-15 Atlas Chem Ind Polymers from ureas and dihalides
US3978024A (en) * 1973-12-28 1976-08-31 General Electric Company Flame retardant polycarbonate composition
US4328244A (en) * 1980-05-21 1982-05-04 The Dow Chemical Company Novel (((substituted-phenyl)methyl)amino)benzenesulfonic acids and pharmaceutically-acceptable salts thereof
US4349568A (en) * 1980-06-12 1982-09-14 The Dow Chemical Company Sulfur-substituted diphenyl ethers having antiviral activity
US4435394A (en) * 1981-12-17 1984-03-06 Shionogi & Co., Ltd. 3-Sulfonamido-benzophenonimine derivatives useful for treating virus infections
US4471110A (en) * 1982-08-02 1984-09-11 E. I. Dupont De Nemours And Company Polyamide of disulfonated diamine and permselective membrane thereof
US4824916A (en) * 1985-03-15 1989-04-25 The Dow Chemical Company Water-insoluble, crosslinked, sulfonated aromatic polyamide
US4604404A (en) * 1985-04-03 1986-08-05 A. H. Robins Company, Inc. Antiviral sulfonated naphthalene formaldehyde condensation polymers
US4783446A (en) * 1985-11-22 1988-11-08 Neushul Mariculture Incorporated Method for the treatment of AIDS virus and other retroviruses
DE3601136A1 (de) * 1986-01-16 1987-07-23 Max Planck Gesellschaft Hemmstoffe der reversen transkriptase fuer prophylaxe und therapie von retrovirus-infektionen in saeugetieren
US4895660A (en) * 1986-07-14 1990-01-23 The Dow Chemical Company Water-soluble aromatic polyamides and polyureas
DE3626309A1 (de) * 1986-08-02 1988-02-18 Stockhausen Chem Fab Gmbh Antivirusmittel
DE3744119A1 (de) * 1987-12-24 1989-07-06 Basf Ag Verwendung von polysulfatierten heparinen
ZA9094B (en) * 1989-01-11 1990-10-31 Merrell Dow Pharma Heparin fraction with anti-hiv activity
US5124149A (en) * 1990-11-07 1992-06-23 The United States Of America As Represented By The Secretary Of Agriculture Compositions and methods for biocontrol using fluorescent brighteners
FR2669535A1 (fr) * 1990-11-26 1992-05-29 Medgenix Group Sa Utilisation a titre de medicament de macromolecules polysulfonees.
DE69106493T2 (de) * 1991-02-05 1995-06-29 Merrell Dow Pharma Sulfonische Stilbenderivate zur Behandlung von Viruserkrankungen.
ATE165345T1 (de) * 1992-02-20 1998-05-15 Merrell Pharma Inc Sulfonsaeurederivate zur behandlung von viruserkrankungen

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2868834A (en) * 1955-02-01 1959-01-13 Ciba Pharm Prod Inc Manufacture of new polythioureas
WO1992000749A1 (en) * 1990-07-09 1992-01-23 Merrell Dow Pharmaceuticals Inc. Anti-herpes virus and cytomegalovirus oligomers
WO1993014146A1 (en) * 1992-01-09 1993-07-22 The Dow Chemical Company Narrow poly- and mono-dispersed anionic oligomers, and their uses, formulations and process

Also Published As

Publication number Publication date
DE69508913D1 (de) 1999-05-12
IL112174A0 (en) 1995-03-15
HUT74694A (en) 1997-01-28
DK0738261T3 (da) 1999-10-18
CN1138323A (zh) 1996-12-18
ZA9410408B (en) 1995-12-11
EP0738261A1 (en) 1996-10-23
NO306613B1 (no) 1999-11-29
WO1995018791A1 (en) 1995-07-13
OA10367A (en) 2001-11-19
FI962725A0 (fi) 1996-07-02
KR100362343B1 (ko) 2003-11-28
ATE178595T1 (de) 1999-04-15
TW303377B (el) 1997-04-21
GR3030521T3 (en) 1999-10-29
NO962782D0 (no) 1996-07-02
US6086864A (en) 2000-07-11
HU9601813D0 (en) 1996-09-30
CA2179988C (en) 2002-10-29
CZ197996A3 (en) 1996-12-11
NO962782L (no) 1996-09-02
AU693853B2 (en) 1998-07-09
ES2133734T3 (es) 1999-09-16
AP9600842A0 (en) 1996-07-31
IL112174A (en) 1999-05-09
NZ279587A (en) 1997-04-24
FI962725A (fi) 1995-07-02
MX9602542A (es) 1997-05-31
CN1070180C (zh) 2001-08-29
EP0738261B1 (en) 1999-04-07
DE69508913T2 (de) 1999-12-02
AU1675695A (en) 1995-08-01
CA2179988A1 (en) 1995-07-13

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