ATE178595T1 - Pharmazeutische polythioharnstoffe enthaltende formulierungen und methode zu ihrer verwendung - Google Patents

Pharmazeutische polythioharnstoffe enthaltende formulierungen und methode zu ihrer verwendung

Info

Publication number
ATE178595T1
ATE178595T1 AT95908436T AT95908436T ATE178595T1 AT E178595 T1 ATE178595 T1 AT E178595T1 AT 95908436 T AT95908436 T AT 95908436T AT 95908436 T AT95908436 T AT 95908436T AT E178595 T1 ATE178595 T1 AT E178595T1
Authority
AT
Austria
Prior art keywords
polythioureas
pharmaceutical formulations
formulations containing
pharmaceutical
formulations
Prior art date
Application number
AT95908436T
Other languages
English (en)
Inventor
Michael J Mullins
William A Fordyce
William J Kruper
Norton P Peet
Alan D Cardin
Original Assignee
Merrell Pharma Inc
Dow Chemical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Pharma Inc, Dow Chemical Co filed Critical Merrell Pharma Inc
Application granted granted Critical
Publication of ATE178595T1 publication Critical patent/ATE178595T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C335/00—Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C335/04—Derivatives of thiourea
    • C07C335/16—Derivatives of thiourea having nitrogen atoms of thiourea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C335/00—Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C335/04—Derivatives of thiourea
    • C07C335/16—Derivatives of thiourea having nitrogen atoms of thiourea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C335/20—Derivatives of thiourea having nitrogen atoms of thiourea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by nitrogen atoms, not being part of nitro or nitroso groups

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT95908436T 1994-01-03 1995-01-03 Pharmazeutische polythioharnstoffe enthaltende formulierungen und methode zu ihrer verwendung ATE178595T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US17658694A 1994-01-03 1994-01-03

Publications (1)

Publication Number Publication Date
ATE178595T1 true ATE178595T1 (de) 1999-04-15

Family

ID=22644965

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95908436T ATE178595T1 (de) 1994-01-03 1995-01-03 Pharmazeutische polythioharnstoffe enthaltende formulierungen und methode zu ihrer verwendung

Country Status (23)

Country Link
US (1) US6086864A (de)
EP (1) EP0738261B1 (de)
KR (1) KR100362343B1 (de)
CN (1) CN1070180C (de)
AP (1) AP638A (de)
AT (1) ATE178595T1 (de)
AU (1) AU693853B2 (de)
CA (1) CA2179988C (de)
CZ (1) CZ197996A3 (de)
DE (1) DE69508913T2 (de)
DK (1) DK0738261T3 (de)
ES (1) ES2133734T3 (de)
FI (1) FI962725A0 (de)
GR (1) GR3030521T3 (de)
HU (1) HUT74694A (de)
IL (1) IL112174A (de)
MX (1) MX9602542A (de)
NO (1) NO306613B1 (de)
NZ (1) NZ279587A (de)
OA (1) OA10367A (de)
TW (1) TW303377B (de)
WO (1) WO1995018791A1 (de)
ZA (1) ZA9410408B (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6186659B1 (en) * 1998-08-21 2001-02-13 Agilent Technologies Inc. Apparatus and method for mixing a film of fluid
CN105582020B (zh) * 2014-10-21 2019-04-16 浙江大学 一种线形聚硫脲和超支化聚硫脲在制备抗肿瘤药物及抗病毒或抗菌药物中的应用
CN107236128A (zh) * 2017-06-21 2017-10-10 华南理工大学 一种异腈、硫和胺的多组分聚合制备聚硫脲的方法及该聚硫脲的应用

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE544868A (de) *
US2833744A (en) * 1953-08-27 1958-05-06 Ciba Pharm Prod Inc Polyureas and process of preparing same
GB781479A (en) * 1953-08-27 1957-08-21 Ciba Ltd New polyureas and process for making them
US2868834A (en) * 1955-02-01 1959-01-13 Ciba Pharm Prod Inc Manufacture of new polythioureas
US3164571A (en) * 1959-12-31 1965-01-05 Union Carbide Corp Polyureas from n-phenyl, phenylene biscarbamyl halide and a diamine
US3528949A (en) * 1968-05-07 1970-09-15 Atlas Chem Ind Polymers from ureas and dihalides
US3978024A (en) * 1973-12-28 1976-08-31 General Electric Company Flame retardant polycarbonate composition
US4328244A (en) * 1980-05-21 1982-05-04 The Dow Chemical Company Novel (((substituted-phenyl)methyl)amino)benzenesulfonic acids and pharmaceutically-acceptable salts thereof
US4349568A (en) * 1980-06-12 1982-09-14 The Dow Chemical Company Sulfur-substituted diphenyl ethers having antiviral activity
US4435394A (en) * 1981-12-17 1984-03-06 Shionogi & Co., Ltd. 3-Sulfonamido-benzophenonimine derivatives useful for treating virus infections
US4471110A (en) * 1982-08-02 1984-09-11 E. I. Dupont De Nemours And Company Polyamide of disulfonated diamine and permselective membrane thereof
US4824916A (en) * 1985-03-15 1989-04-25 The Dow Chemical Company Water-insoluble, crosslinked, sulfonated aromatic polyamide
US4604404A (en) * 1985-04-03 1986-08-05 A. H. Robins Company, Inc. Antiviral sulfonated naphthalene formaldehyde condensation polymers
US4783446A (en) * 1985-11-22 1988-11-08 Neushul Mariculture Incorporated Method for the treatment of AIDS virus and other retroviruses
DE3601136A1 (de) * 1986-01-16 1987-07-23 Max Planck Gesellschaft Hemmstoffe der reversen transkriptase fuer prophylaxe und therapie von retrovirus-infektionen in saeugetieren
US4895660A (en) * 1986-07-14 1990-01-23 The Dow Chemical Company Water-soluble aromatic polyamides and polyureas
DE3626309A1 (de) * 1986-08-02 1988-02-18 Stockhausen Chem Fab Gmbh Antivirusmittel
DE3744119A1 (de) * 1987-12-24 1989-07-06 Basf Ag Verwendung von polysulfatierten heparinen
ZA9094B (en) * 1989-01-11 1990-10-31 Merrell Dow Pharma Heparin fraction with anti-hiv activity
US5276182A (en) * 1990-07-09 1994-01-04 The Dow Chemical Company Process for preparing polyurea oligomers
US5124149A (en) * 1990-11-07 1992-06-23 The United States Of America As Represented By The Secretary Of Agriculture Compositions and methods for biocontrol using fluorescent brighteners
FR2669535A1 (fr) * 1990-11-26 1992-05-29 Medgenix Group Sa Utilisation a titre de medicament de macromolecules polysulfonees.
EP0498095B1 (de) * 1991-02-05 1995-01-04 Merrell Dow Pharmaceuticals Inc. Sulfonische Stilbenderivate zur Behandlung von Viruserkrankungen
US5424063A (en) * 1992-01-09 1995-06-13 The Dow Chemical Company Narrow poly- and mono-dispersed anionic oligomers, and their uses, formulations and process
WO1993016992A1 (en) * 1992-02-20 1993-09-02 Merrell Dow Pharmaceuticals Inc. Sulfonic acid derivatives in the treatment of viral diseases

Also Published As

Publication number Publication date
HUT74694A (en) 1997-01-28
KR100362343B1 (ko) 2003-11-28
OA10367A (en) 2001-11-19
EP0738261A1 (de) 1996-10-23
AU1675695A (en) 1995-08-01
NO962782D0 (no) 1996-07-02
MX9602542A (es) 1997-05-31
FI962725A (fi) 1995-07-02
CZ197996A3 (en) 1996-12-11
EP0738261B1 (de) 1999-04-07
GR3030521T3 (en) 1999-10-29
CN1070180C (zh) 2001-08-29
IL112174A0 (en) 1995-03-15
AP9600842A0 (en) 1996-07-31
DE69508913D1 (de) 1999-05-12
CA2179988A1 (en) 1995-07-13
CN1138323A (zh) 1996-12-18
NO962782L (no) 1996-09-02
IL112174A (en) 1999-05-09
NZ279587A (en) 1997-04-24
AP638A (en) 1998-04-14
DE69508913T2 (de) 1999-12-02
TW303377B (de) 1997-04-21
US6086864A (en) 2000-07-11
NO306613B1 (no) 1999-11-29
FI962725A0 (fi) 1996-07-02
DK0738261T3 (da) 1999-10-18
CA2179988C (en) 2002-10-29
ZA9410408B (en) 1995-12-11
AU693853B2 (en) 1998-07-09
ES2133734T3 (es) 1999-09-16
WO1995018791A1 (en) 1995-07-13
HU9601813D0 (en) 1996-09-30

Similar Documents

Publication Publication Date Title
EE9700145A (et) Tsükloalkaanpüridiinid, nende valmistamismeetod, kasutamine ravimite tootmiseks ja nimetatud ühendeid sisaldavad ravimid
DE69233474D1 (de) Pharmazeutische Zusammensetzung enthaltend S-Nitrosoimmunoglobuline und Verwendung davon
DE69505657D1 (de) Fluorcarbonetherhybriden enthaltende physiologich akzeptabele emulsionen und verwendungsverfahren
EE03742B1 (et) Tramadooli mitmikühikulised preparaadid ja nende valmistamismeetod
HUP0000808A3 (en) Pharmaceutical composition of fenofibrate and method for preparing same
ITMI942025A0 (it) Composizioni farmaceutiche contenenti microorganismi ingegnerizzati e loro uso per terapia
DE69830222D1 (de) Reformer und Methode zu dessen Betreiben
EE03280B1 (et) Pidurdatud vabanemisega ravimkuulikesed ja neid sisaldav ravimpreparaat
DE69828895D1 (de) Alpha-aryl-n-alkylnitrone sowie diese enthaltende pharmazeutische zubereitungen
HUP0202338A2 (en) Pharmaceutical composition containing fenofibrate and preparation method
NO984878D0 (no) Fremstilling og anvendelse som medikamenter av 3-alkoksypyridin-2-karboksylsyreamidestere
DE69411604D1 (de) Wirkstoffzusammensetzung und Verfahren zu ihrer Herstellung
DE69802739T2 (de) Avalanche-Photodiode und Methode zu deren Herstellung
AP9801208A0 (en) Orthomolecular medical use of L-citrulline for vasoprotection relaxative smooth muscle tone and cell protection
DE59608606D1 (de) Cyclosprorin(e) enthaltende pharmazeutische zubereitung zur oralen applikation und verfahren zu ihrer herstellung
ATE308365T1 (de) Zusammensetzungen zur oralen verabreichung von taxanen und deren verwendung
IL123849A0 (en) Pharmaceutical composition useful for nucleic acid transfection and use thereof
NO20001717D0 (no) Serotonin-inneholdende formulering for oral administrering og anvendelse av samme
ATE178595T1 (de) Pharmazeutische polythioharnstoffe enthaltende formulierungen und methode zu ihrer verwendung
DE69808793D1 (de) Pharmazeutische zusammensetzungen aus dalfopristine und quinupristine und verfahren zu ihrer herstellung
DE59606062D1 (de) Substituierte Benzolsulfonylharnstoffe und -thioharnstoffe, Verfahren zu ihrer Herstellung und ihrer Verwendung zur Herstellung pharmazeutischer Präparate sowie sie enthaltende pharmazeutische Präparate
AU7001796A (en) Benzoic acid compounds and medicinal use thereof
GB9514816D0 (en) Substances and their medical use
IL113415A0 (en) Dihydrodibenzoquinolinediones their preparation and use and pharmaceutical compositions containing them
DE59610705D1 (de) Pharmazeutische präparate zur oralen anwendung und verfahren zu ihrer herstellung

Legal Events

Date Code Title Description
REN Ceased due to non-payment of the annual fee