GR3030521T3 - Pharmaceutical formulations comprising polythiourea and method of use thereof - Google Patents

Pharmaceutical formulations comprising polythiourea and method of use thereof

Info

Publication number
GR3030521T3
GR3030521T3 GR990401596T GR990401596T GR3030521T3 GR 3030521 T3 GR3030521 T3 GR 3030521T3 GR 990401596 T GR990401596 T GR 990401596T GR 990401596 T GR990401596 T GR 990401596T GR 3030521 T3 GR3030521 T3 GR 3030521T3
Authority
GR
Greece
Prior art keywords
polythiourea
pharmaceutical formulations
formulations
pharmaceutical
Prior art date
Application number
GR990401596T
Other languages
English (en)
Inventor
Michael J Mullins
William A Fordyce
William J Kruper
Norton P Peet
Alan D Cardin
Original Assignee
Merrell Pharma Inc
Merrell Dow Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Pharma Inc, Merrell Dow Pharma filed Critical Merrell Pharma Inc
Publication of GR3030521T3 publication Critical patent/GR3030521T3/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C335/00—Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C335/04—Derivatives of thiourea
    • C07C335/16—Derivatives of thiourea having nitrogen atoms of thiourea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C335/00—Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C335/04—Derivatives of thiourea
    • C07C335/16—Derivatives of thiourea having nitrogen atoms of thiourea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C335/20—Derivatives of thiourea having nitrogen atoms of thiourea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by nitrogen atoms, not being part of nitro or nitroso groups

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
GR990401596T 1994-01-03 1999-06-16 Pharmaceutical formulations comprising polythiourea and method of use thereof GR3030521T3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US17658694A 1994-01-03 1994-01-03
PCT/US1995/000118 WO1995018791A1 (en) 1994-01-03 1995-01-03 Pharmaceutical formulations comprising polythiourea and method of use thereof

Publications (1)

Publication Number Publication Date
GR3030521T3 true GR3030521T3 (en) 1999-10-29

Family

ID=22644965

Family Applications (1)

Application Number Title Priority Date Filing Date
GR990401596T GR3030521T3 (en) 1994-01-03 1999-06-16 Pharmaceutical formulations comprising polythiourea and method of use thereof

Country Status (23)

Country Link
US (1) US6086864A (el)
EP (1) EP0738261B1 (el)
KR (1) KR100362343B1 (el)
CN (1) CN1070180C (el)
AP (1) AP638A (el)
AT (1) ATE178595T1 (el)
AU (1) AU693853B2 (el)
CA (1) CA2179988C (el)
CZ (1) CZ197996A3 (el)
DE (1) DE69508913T2 (el)
DK (1) DK0738261T3 (el)
ES (1) ES2133734T3 (el)
FI (1) FI962725A0 (el)
GR (1) GR3030521T3 (el)
HU (1) HUT74694A (el)
IL (1) IL112174A (el)
MX (1) MX9602542A (el)
NO (1) NO306613B1 (el)
NZ (1) NZ279587A (el)
OA (1) OA10367A (el)
TW (1) TW303377B (el)
WO (1) WO1995018791A1 (el)
ZA (1) ZA9410408B (el)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6186659B1 (en) * 1998-08-21 2001-02-13 Agilent Technologies Inc. Apparatus and method for mixing a film of fluid
CN105582020B (zh) * 2014-10-21 2019-04-16 浙江大学 一种线形聚硫脲和超支化聚硫脲在制备抗肿瘤药物及抗病毒或抗菌药物中的应用
CN107236128A (zh) * 2017-06-21 2017-10-10 华南理工大学 一种异腈、硫和胺的多组分聚合制备聚硫脲的方法及该聚硫脲的应用

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE544868A (el) *
GB781479A (en) * 1953-08-27 1957-08-21 Ciba Ltd New polyureas and process for making them
US2833744A (en) * 1953-08-27 1958-05-06 Ciba Pharm Prod Inc Polyureas and process of preparing same
US2868834A (en) * 1955-02-01 1959-01-13 Ciba Pharm Prod Inc Manufacture of new polythioureas
US3164571A (en) * 1959-12-31 1965-01-05 Union Carbide Corp Polyureas from n-phenyl, phenylene biscarbamyl halide and a diamine
US3528949A (en) * 1968-05-07 1970-09-15 Atlas Chem Ind Polymers from ureas and dihalides
US3978024A (en) * 1973-12-28 1976-08-31 General Electric Company Flame retardant polycarbonate composition
US4328244A (en) * 1980-05-21 1982-05-04 The Dow Chemical Company Novel (((substituted-phenyl)methyl)amino)benzenesulfonic acids and pharmaceutically-acceptable salts thereof
US4349568A (en) * 1980-06-12 1982-09-14 The Dow Chemical Company Sulfur-substituted diphenyl ethers having antiviral activity
US4435394A (en) * 1981-12-17 1984-03-06 Shionogi & Co., Ltd. 3-Sulfonamido-benzophenonimine derivatives useful for treating virus infections
US4471110A (en) * 1982-08-02 1984-09-11 E. I. Dupont De Nemours And Company Polyamide of disulfonated diamine and permselective membrane thereof
US4824916A (en) * 1985-03-15 1989-04-25 The Dow Chemical Company Water-insoluble, crosslinked, sulfonated aromatic polyamide
US4604404A (en) * 1985-04-03 1986-08-05 A. H. Robins Company, Inc. Antiviral sulfonated naphthalene formaldehyde condensation polymers
US4783446A (en) * 1985-11-22 1988-11-08 Neushul Mariculture Incorporated Method for the treatment of AIDS virus and other retroviruses
DE3601136A1 (de) * 1986-01-16 1987-07-23 Max Planck Gesellschaft Hemmstoffe der reversen transkriptase fuer prophylaxe und therapie von retrovirus-infektionen in saeugetieren
US4895660A (en) * 1986-07-14 1990-01-23 The Dow Chemical Company Water-soluble aromatic polyamides and polyureas
DE3626309A1 (de) * 1986-08-02 1988-02-18 Stockhausen Chem Fab Gmbh Antivirusmittel
DE3744119A1 (de) * 1987-12-24 1989-07-06 Basf Ag Verwendung von polysulfatierten heparinen
ZA9094B (en) * 1989-01-11 1990-10-31 Merrell Dow Pharma Heparin fraction with anti-hiv activity
US5276182A (en) * 1990-07-09 1994-01-04 The Dow Chemical Company Process for preparing polyurea oligomers
US5124149A (en) * 1990-11-07 1992-06-23 The United States Of America As Represented By The Secretary Of Agriculture Compositions and methods for biocontrol using fluorescent brighteners
FR2669535A1 (fr) * 1990-11-26 1992-05-29 Medgenix Group Sa Utilisation a titre de medicament de macromolecules polysulfonees.
EP0498095B1 (en) * 1991-02-05 1995-01-04 Merrell Dow Pharmaceuticals Inc. Sulfonic stilbene derivatives in the treatment of viral diseases
US5424063A (en) * 1992-01-09 1995-06-13 The Dow Chemical Company Narrow poly- and mono-dispersed anionic oligomers, and their uses, formulations and process
EP0626945B1 (en) * 1992-02-20 1998-04-22 Merrell Pharmaceuticals Inc. Sulfonic acid derivatives in the treatment of viral diseases

Also Published As

Publication number Publication date
AP9600842A0 (en) 1996-07-31
EP0738261A1 (en) 1996-10-23
NO962782L (no) 1996-09-02
EP0738261B1 (en) 1999-04-07
IL112174A0 (en) 1995-03-15
FI962725A (fi) 1995-07-02
HUT74694A (en) 1997-01-28
ES2133734T3 (es) 1999-09-16
KR100362343B1 (ko) 2003-11-28
FI962725A0 (fi) 1996-07-02
DE69508913T2 (de) 1999-12-02
DK0738261T3 (da) 1999-10-18
ZA9410408B (en) 1995-12-11
TW303377B (el) 1997-04-21
ATE178595T1 (de) 1999-04-15
WO1995018791A1 (en) 1995-07-13
DE69508913D1 (de) 1999-05-12
AU693853B2 (en) 1998-07-09
NO306613B1 (no) 1999-11-29
OA10367A (en) 2001-11-19
NZ279587A (en) 1997-04-24
CN1138323A (zh) 1996-12-18
CZ197996A3 (en) 1996-12-11
MX9602542A (es) 1997-05-31
US6086864A (en) 2000-07-11
NO962782D0 (no) 1996-07-02
AP638A (en) 1998-04-14
IL112174A (en) 1999-05-09
CA2179988A1 (en) 1995-07-13
CA2179988C (en) 2002-10-29
HU9601813D0 (en) 1996-09-30
CN1070180C (zh) 2001-08-29
AU1675695A (en) 1995-08-01

Similar Documents

Publication Publication Date Title
GB9422571D0 (en) Haemorrihoidal compositions and method of use
HUP0000808A3 (en) Pharmaceutical composition of fenofibrate and method for preparing same
EP0760635A4 (en) EXTENSIBLE DENTAL IMPLANT AND MANUFACTURING METHOD THEREOF
EP0711572A4 (en) INHALATOR AND METHOD FOR USE THEREOF
ZA947138B (en) Skin care method and composition
AUPO727097A0 (en) Method of treatment of hepatoma and pharmaceutical compositions for use therein
GB9710800D0 (en) Pharmaceutical composition and method of preparing it
IL113431A0 (en) Naphthalene derivatives method of preparation and use and pharmaceutical compositions containing them
GB2294637B (en) Therapeutic compositions and methods of use
EP0747351A3 (en) Thiocationic lipids, pharmaceutical compositions and their methods of use
ZA9410408B (en) Pharmaceutical formulations comprising polythiourea and method of use thereof
IL116532A0 (en) 1-oxo-2-(phenylsulphonylamino) pentylpiperdine derivatives their preparation and their therapeutic application
IL113415A0 (en) Dihydrodibenzoquinolinediones their preparation and use and pharmaceutical compositions containing them
IL114161A0 (en) Amido- quinoxalinediones pharmaceutical compositions containing them and their use
GB9304745D0 (en) Use of pharmaceutical formulations
PL303822A1 (en) Therapeutic compositions containing ipsapyrone and method of obtaining them
ZA951789B (en) Pharmaceutical materials and methods of administration
ZA947139B (en) Skin care method and composition
GB9608927D0 (en) Method of treatment and pharmaceutical composition
ZA956970B (en) Improved pharmaceutical formulations their preparation and use
HU9400634D0 (en) Vaccine and diagnosticum against parvovirosis of gooses and barbari duks
SI0785770T1 (en) Hemorrhoidal compositions and method of use
GB9419698D0 (en) Pharmaceutical compositions and their use
ZA95871B (en) Mutable composition and method of use thereof
IL111090A0 (en) Mimetopes and pharmaceutical compositions and vaccines comprising them