MX9602542A - Formulaciones farmaceuticas que comprenden politiourea y metodo para su uso. - Google Patents

Formulaciones farmaceuticas que comprenden politiourea y metodo para su uso.

Info

Publication number
MX9602542A
MX9602542A MX9602542A MX9602542A MX9602542A MX 9602542 A MX9602542 A MX 9602542A MX 9602542 A MX9602542 A MX 9602542A MX 9602542 A MX9602542 A MX 9602542A MX 9602542 A MX9602542 A MX 9602542A
Authority
MX
Mexico
Prior art keywords
oligomers
polythiourea
pharmaceutical formulations
polythioureas
aids
Prior art date
Application number
MX9602542A
Other languages
English (en)
Inventor
Michael J Mullins
William A Fordyce
William J Kruper
Norton P Peet
Alan D Cardin
Original Assignee
Merrell Pharma Inc
Dow Chemical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Pharma Inc, Dow Chemical Co filed Critical Merrell Pharma Inc
Publication of MX9602542A publication Critical patent/MX9602542A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C335/00—Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C335/04—Derivatives of thiourea
    • C07C335/16—Derivatives of thiourea having nitrogen atoms of thiourea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C335/00—Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C335/04—Derivatives of thiourea
    • C07C335/16—Derivatives of thiourea having nitrogen atoms of thiourea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C335/20—Derivatives of thiourea having nitrogen atoms of thiourea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by nitrogen atoms, not being part of nitro or nitroso groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Los oligomeros de la presente invencion son politioureas que tienen de 3 a 50 unidades recurrentes derivadas de diaminas aromáticas substituidas con grupos anionicos, y que tienen un numero de peso molecular promedio menor que 10,000. Estos oligomeros son solubles en agua, preferiblemente tienen una estructura de la base rígida, y son farmacéuticamente aceptables. Los oligomeros son utiles para el tratamiento y/o diagnostico de SIDA.
MX9602542A 1994-01-03 1995-01-03 Formulaciones farmaceuticas que comprenden politiourea y metodo para su uso. MX9602542A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US17658694A 1994-01-03 1994-01-03
PCT/US1995/000118 WO1995018791A1 (en) 1994-01-03 1995-01-03 Pharmaceutical formulations comprising polythiourea and method of use thereof

Publications (1)

Publication Number Publication Date
MX9602542A true MX9602542A (es) 1997-05-31

Family

ID=22644965

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9602542A MX9602542A (es) 1994-01-03 1995-01-03 Formulaciones farmaceuticas que comprenden politiourea y metodo para su uso.

Country Status (23)

Country Link
US (1) US6086864A (es)
EP (1) EP0738261B1 (es)
KR (1) KR100362343B1 (es)
CN (1) CN1070180C (es)
AP (1) AP638A (es)
AT (1) ATE178595T1 (es)
AU (1) AU693853B2 (es)
CA (1) CA2179988C (es)
CZ (1) CZ197996A3 (es)
DE (1) DE69508913T2 (es)
DK (1) DK0738261T3 (es)
ES (1) ES2133734T3 (es)
FI (1) FI962725A0 (es)
GR (1) GR3030521T3 (es)
HU (1) HUT74694A (es)
IL (1) IL112174A (es)
MX (1) MX9602542A (es)
NO (1) NO306613B1 (es)
NZ (1) NZ279587A (es)
OA (1) OA10367A (es)
TW (1) TW303377B (es)
WO (1) WO1995018791A1 (es)
ZA (1) ZA9410408B (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6186659B1 (en) * 1998-08-21 2001-02-13 Agilent Technologies Inc. Apparatus and method for mixing a film of fluid
CN105582020B (zh) * 2014-10-21 2019-04-16 浙江大学 一种线形聚硫脲和超支化聚硫脲在制备抗肿瘤药物及抗病毒或抗菌药物中的应用
CN107236128A (zh) * 2017-06-21 2017-10-10 华南理工大学 一种异腈、硫和胺的多组分聚合制备聚硫脲的方法及该聚硫脲的应用

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE544868A (es) *
US2833744A (en) * 1953-08-27 1958-05-06 Ciba Pharm Prod Inc Polyureas and process of preparing same
GB781479A (en) * 1953-08-27 1957-08-21 Ciba Ltd New polyureas and process for making them
US2868834A (en) * 1955-02-01 1959-01-13 Ciba Pharm Prod Inc Manufacture of new polythioureas
US3164571A (en) * 1959-12-31 1965-01-05 Union Carbide Corp Polyureas from n-phenyl, phenylene biscarbamyl halide and a diamine
US3528949A (en) * 1968-05-07 1970-09-15 Atlas Chem Ind Polymers from ureas and dihalides
US3978024A (en) * 1973-12-28 1976-08-31 General Electric Company Flame retardant polycarbonate composition
US4328244A (en) * 1980-05-21 1982-05-04 The Dow Chemical Company Novel (((substituted-phenyl)methyl)amino)benzenesulfonic acids and pharmaceutically-acceptable salts thereof
US4349568A (en) * 1980-06-12 1982-09-14 The Dow Chemical Company Sulfur-substituted diphenyl ethers having antiviral activity
US4435394A (en) * 1981-12-17 1984-03-06 Shionogi & Co., Ltd. 3-Sulfonamido-benzophenonimine derivatives useful for treating virus infections
US4471110A (en) * 1982-08-02 1984-09-11 E. I. Dupont De Nemours And Company Polyamide of disulfonated diamine and permselective membrane thereof
US4824916A (en) * 1985-03-15 1989-04-25 The Dow Chemical Company Water-insoluble, crosslinked, sulfonated aromatic polyamide
US4604404A (en) * 1985-04-03 1986-08-05 A. H. Robins Company, Inc. Antiviral sulfonated naphthalene formaldehyde condensation polymers
US4783446A (en) * 1985-11-22 1988-11-08 Neushul Mariculture Incorporated Method for the treatment of AIDS virus and other retroviruses
DE3601136A1 (de) * 1986-01-16 1987-07-23 Max Planck Gesellschaft Hemmstoffe der reversen transkriptase fuer prophylaxe und therapie von retrovirus-infektionen in saeugetieren
US4895660A (en) * 1986-07-14 1990-01-23 The Dow Chemical Company Water-soluble aromatic polyamides and polyureas
DE3626309A1 (de) * 1986-08-02 1988-02-18 Stockhausen Chem Fab Gmbh Antivirusmittel
DE3744119A1 (de) * 1987-12-24 1989-07-06 Basf Ag Verwendung von polysulfatierten heparinen
ZA9094B (en) * 1989-01-11 1990-10-31 Merrell Dow Pharma Heparin fraction with anti-hiv activity
US5276182A (en) * 1990-07-09 1994-01-04 The Dow Chemical Company Process for preparing polyurea oligomers
US5124149A (en) * 1990-11-07 1992-06-23 The United States Of America As Represented By The Secretary Of Agriculture Compositions and methods for biocontrol using fluorescent brighteners
FR2669535A1 (fr) * 1990-11-26 1992-05-29 Medgenix Group Sa Utilisation a titre de medicament de macromolecules polysulfonees.
DE69106493T2 (de) * 1991-02-05 1995-06-29 Merrell Dow Pharma Sulfonische Stilbenderivate zur Behandlung von Viruserkrankungen.
US5424063A (en) * 1992-01-09 1995-06-13 The Dow Chemical Company Narrow poly- and mono-dispersed anionic oligomers, and their uses, formulations and process
CA2130360C (en) * 1992-02-20 1998-06-09 Allan D. Cardin Sulfonic acid derivatives in the treatment of viral diseases

Also Published As

Publication number Publication date
DK0738261T3 (da) 1999-10-18
AP638A (en) 1998-04-14
AP9600842A0 (en) 1996-07-31
ES2133734T3 (es) 1999-09-16
EP0738261B1 (en) 1999-04-07
OA10367A (en) 2001-11-19
IL112174A (en) 1999-05-09
NO962782L (no) 1996-09-02
WO1995018791A1 (en) 1995-07-13
HUT74694A (en) 1997-01-28
ZA9410408B (en) 1995-12-11
CA2179988C (en) 2002-10-29
AU693853B2 (en) 1998-07-09
IL112174A0 (en) 1995-03-15
CN1070180C (zh) 2001-08-29
NZ279587A (en) 1997-04-24
DE69508913D1 (de) 1999-05-12
KR100362343B1 (ko) 2003-11-28
AU1675695A (en) 1995-08-01
CN1138323A (zh) 1996-12-18
GR3030521T3 (en) 1999-10-29
EP0738261A1 (en) 1996-10-23
TW303377B (es) 1997-04-21
HU9601813D0 (en) 1996-09-30
FI962725A0 (fi) 1996-07-02
US6086864A (en) 2000-07-11
NO306613B1 (no) 1999-11-29
FI962725A (fi) 1995-07-02
ATE178595T1 (de) 1999-04-15
DE69508913T2 (de) 1999-12-02
CZ197996A3 (en) 1996-12-11
CA2179988A1 (en) 1995-07-13
NO962782D0 (no) 1996-07-02

Similar Documents

Publication Publication Date Title
EP1133989A3 (en) Polymer compositions for use in therapy
EP0767191A3 (en) Polymer, preparation process thereof, hairtreating compositions and cosmetic compositions
CA2326510A1 (en) Dextran formulations and method for treatment of inflammatory joint disorders
NO982703D0 (no) Lineµre blokkpolymerer som omfatter urea- og uretangrupper, fremgangsmÕte til fremstilling av lineµre blokkpolymerer og anvendelse av blokkpolymerene som implantater
HUP0003323A2 (hu) Vorikonazolt tartalmazó gyógyászati készítmények
HUT70211A (en) Proteinoid carriers and methods for preparation and use thereof
IL117750A0 (en) Cell growth substrate polymer
TJ392B (en) Fraction of copolymer-1 and method prodaction of it, composition for the treatment of multiple sclerosis, farmaceutical composition, method for the t reatment of multiple sclerosis.
WO1996039156A3 (en) Phosphate-binding polymers for oral administration
HUP0101073A2 (hu) Közepes sűrűségű etilén polimerek, eljárás előállításukra és karbonilcsoportot tartalmazó láncátvivő szerek alkalmazása az eljárásnál
ZA200300712B (en) Pharmaceutical compositions for the treatment of mucositis, stomatitis and Behcet's syndrome.
BG101059A (en) Compositions based on propylene copolymers having statistical distribution of monomer links, method for their preparation and thermoresistant multilayer foil based on these compositions
HUP0101189A2 (hu) Vas-dextrán vegyület felhasználása vashiány megelőzésére és kezelésére szolgáló gyógyszerkészítmény alkotórészeként, eljárás a nevezett vas-dextrán vegyület előállítására, és a nevezett vegyület felhasználása parenterálisan beadható gyógyszerkészítmény...
IL115138A (en) Implantable polymer-containing molded articles for the administration of active substances to plants and processes for the preparation thereof
CA2154103A1 (en) Treatment of Mucous Membrane Disease, Trauma or Condition and for the Relief of Pain
ES2099962T3 (es) Oligomeros que inhiben la proliferacion.
IL132214A0 (en) Use of zinc hyaluronate against peptic ulcer
DE50006334D1 (en) Thermoplastische nanocomposites
MX9602542A (es) Formulaciones farmaceuticas que comprenden politiourea y metodo para su uso.
EP0744176A3 (en) Methods for inhibiting bone loss
AU3280300A (en) Preparations for treating keratin fibres
CA2186760A1 (fr) Utilisation de biopolymeres pour le traitement des muscles
SE9403905D0 (sv) New formulations
Wilczek et al. Regular Star-Shaped Polydimethylsiloxane Polymers
CA2277873A1 (en) A method for treating dentures