AP425A - "Benzofuran derivatives and their use in the treatment of migraine". - Google Patents

"Benzofuran derivatives and their use in the treatment of migraine". Download PDF

Info

Publication number
AP425A
AP425A APAP/P/1993/000581A AP9300581A AP425A AP 425 A AP425 A AP 425A AP 9300581 A AP9300581 A AP 9300581A AP 425 A AP425 A AP 425A
Authority
AP
ARIPO
Prior art keywords
formula
compound
ethyl
benzofuranyl
acetyl
Prior art date
Application number
APAP/P/1993/000581A
Other languages
English (en)
Other versions
AP9300581A0 (en
Inventor
Peter Charles North
Sjoerd Nicolaas Wadman
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of AP9300581A0 publication Critical patent/AP9300581A0/xx
Application granted granted Critical
Publication of AP425A publication Critical patent/AP425A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/10Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/04Nitro compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/06Antimigraine agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Furan Compounds (AREA)
APAP/P/1993/000581A 1992-10-16 1993-10-15 "Benzofuran derivatives and their use in the treatment of migraine". AP425A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB929221761A GB9221761D0 (en) 1992-10-16 1992-10-16 Chemical compounds

Publications (2)

Publication Number Publication Date
AP9300581A0 AP9300581A0 (en) 1993-10-31
AP425A true AP425A (en) 1995-11-08

Family

ID=10723562

Family Applications (1)

Application Number Title Priority Date Filing Date
APAP/P/1993/000581A AP425A (en) 1992-10-16 1993-10-15 "Benzofuran derivatives and their use in the treatment of migraine".

Country Status (24)

Country Link
US (1) US5494910A (es)
EP (1) EP0664804A1 (es)
JP (1) JPH06211842A (es)
KR (1) KR940009179A (es)
CN (1) CN1092420A (es)
AP (1) AP425A (es)
AU (1) AU5333794A (es)
CA (1) CA2146569A1 (es)
CZ (1) CZ96895A3 (es)
EC (1) ECSP941050A (es)
FI (1) FI951798A (es)
GB (1) GB9221761D0 (es)
HU (1) HUT72752A (es)
IL (1) IL107302A0 (es)
IS (1) IS4081A (es)
MX (1) MX9306394A (es)
NO (1) NO951433D0 (es)
PE (1) PE51294A1 (es)
PL (1) PL308357A1 (es)
RU (1) RU95110110A (es)
SI (1) SI9300542A (es)
TW (1) TW262473B (es)
WO (1) WO1994008993A1 (es)
ZA (1) ZA937633B (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9407447D0 (en) * 1994-04-14 1994-06-08 Glaxo Group Ltd Chemical compounds
WO1995032196A1 (en) * 1994-05-19 1995-11-30 Merck Sharp & Dohme Limited Piperazine, piperidine and tetrahydropyridine derivatives of indol-3-ylalkyl as 5-ht1d-alpha agonists
GB9610979D0 (en) * 1996-05-24 1996-07-31 Merck Sharp & Dohme Therapeutic agents
JP2001501946A (ja) * 1996-10-08 2001-02-13 イーライ・リリー・アンド・カンパニー 新規セロトニン5―ht▲下1f▼アゴニスト
US5891885A (en) * 1996-10-09 1999-04-06 Algos Pharmaceutical Corporation Method for treating migraine
US20030198669A1 (en) * 2001-07-05 2003-10-23 R.T. Alamo Ventures I, Llc Compositions and methods for rapid dissolving formulations of dihydroergotamine and caffeine for the treatment of migraine
US20030017175A1 (en) * 2001-07-05 2003-01-23 R.T. Alamo Ventures I, Inc. Sublingual administration of dihydroergotamine for the treatment of migraine
US6685951B2 (en) 2001-07-05 2004-02-03 R. T. Alamo Ventures I, Inc. Administration of dihydroergotamine as a sublingual spray or aerosol for the treatment of migraine
US9399053B2 (en) 2011-07-22 2016-07-26 The University Of Chicago Treatments for migraine and related disorders
KR101443041B1 (ko) * 2013-05-06 2014-09-23 (주)하이레벤 태양광 발전설비의 효율향상설비
WO2023018864A1 (en) 2021-08-12 2023-02-16 Psilosterics, Llc Hallucinogenic and non-hallucinogenic serotonin receptor agonists and methods of making and using the same

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1670105A1 (de) * 1966-07-08 1970-12-10 Byk Gulden Lomberg Chem Fab Verfahren zur Herstellung von Benzofuryl (3)-alkylaminen und deren Salzen
EP0398413A1 (en) * 1989-05-16 1990-11-22 Duphar International Research B.V "3,4-dehydropiperidine derivatives having psychotropic activity

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1670105A1 (de) * 1966-07-08 1970-12-10 Byk Gulden Lomberg Chem Fab Verfahren zur Herstellung von Benzofuryl (3)-alkylaminen und deren Salzen
EP0398413A1 (en) * 1989-05-16 1990-11-22 Duphar International Research B.V "3,4-dehydropiperidine derivatives having psychotropic activity

Also Published As

Publication number Publication date
GB9221761D0 (en) 1992-12-02
NO951433L (no) 1995-04-12
IL107302A0 (en) 1994-01-25
HUT72752A (en) 1996-05-28
AU5333794A (en) 1994-05-09
WO1994008993A1 (en) 1994-04-28
CA2146569A1 (en) 1994-04-28
US5494910A (en) 1996-02-27
PE51294A1 (es) 1995-01-06
FI951798A0 (fi) 1995-04-13
HU9501073D0 (en) 1995-06-28
ECSP941050A (es) 1994-11-16
JPH06211842A (ja) 1994-08-02
CZ96895A3 (en) 1995-12-13
TW262473B (es) 1995-11-11
MX9306394A (es) 1994-05-31
CN1092420A (zh) 1994-09-21
PL308357A1 (en) 1995-07-24
KR940009179A (ko) 1994-05-20
FI951798A (fi) 1995-04-13
EP0664804A1 (en) 1995-08-02
SI9300542A (en) 1994-06-30
IS4081A (is) 1994-04-17
ZA937633B (en) 1994-08-01
AP9300581A0 (en) 1993-10-31
NO951433D0 (no) 1995-04-12
RU95110110A (ru) 1996-12-27

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