NO951433L - Kjemiske forbindelser - Google Patents
Kjemiske forbindelserInfo
- Publication number
- NO951433L NO951433L NO951433A NO951433A NO951433L NO 951433 L NO951433 L NO 951433L NO 951433 A NO951433 A NO 951433A NO 951433 A NO951433 A NO 951433A NO 951433 L NO951433 L NO 951433L
- Authority
- NO
- Norway
- Prior art keywords
- formula
- alkyl
- hydrogen
- different
- same
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/10—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/04—Nitro compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pain & Pain Management (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Furan Compounds (AREA)
Abstract
Denne oppfinnelse vedrører benzofuranderivater, frem- gangsmåter for deres fremstilling, farmasøytiske blandinger inneholdende dem og deres medisinske anvendelse, spesielt forbindelser og blandinger for bruk ved behandling av migrene. Spesielt tilveiebringer oppfinnelsen en forbindelse med formel (I) hvori R1 er -CH2CONR3R*; R2 er -CH2CH2NR5R6; R3 og R*, sammen med N-atomet som de er knyttet til, danner en mettet 4- til 7- leddet ring med formelen (II), hvor Z er en gruppe med formelen -CR7R8-, -O- eller -NR9-; R5 og R6, som kan være like eller forskjellige, er hydrogen eller Cj^alkyl; R7 og R8, som kan være like eller forskjellige, er hydrogen, hydroksy eller C^alkoksy; R» er -S02R10, -COR10 eller -COOR10; R10 er C^alkyl; og farmasøytisk akseptable salter og solvater derav.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB929221761A GB9221761D0 (en) | 1992-10-16 | 1992-10-16 | Chemical compounds |
| PCT/EP1993/002833 WO1994008993A1 (en) | 1992-10-16 | 1993-10-14 | Benzofuran derivatives as 5-ht1-like receptor antagonists |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO951433L true NO951433L (no) | 1995-04-12 |
| NO951433D0 NO951433D0 (no) | 1995-04-12 |
Family
ID=10723562
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO951433A NO951433D0 (no) | 1992-10-16 | 1995-04-12 | Kjemiske forbindelser |
Country Status (24)
| Country | Link |
|---|---|
| US (1) | US5494910A (no) |
| EP (1) | EP0664804A1 (no) |
| JP (1) | JPH06211842A (no) |
| KR (1) | KR940009179A (no) |
| CN (1) | CN1092420A (no) |
| AP (1) | AP425A (no) |
| AU (1) | AU5333794A (no) |
| CA (1) | CA2146569A1 (no) |
| CZ (1) | CZ96895A3 (no) |
| EC (1) | ECSP941050A (no) |
| FI (1) | FI951798A (no) |
| GB (1) | GB9221761D0 (no) |
| HU (1) | HUT72752A (no) |
| IL (1) | IL107302A0 (no) |
| IS (1) | IS4081A (no) |
| MX (1) | MX9306394A (no) |
| NO (1) | NO951433D0 (no) |
| PE (1) | PE51294A1 (no) |
| PL (1) | PL308357A1 (no) |
| RU (1) | RU95110110A (no) |
| SI (1) | SI9300542A (no) |
| TW (1) | TW262473B (no) |
| WO (1) | WO1994008993A1 (no) |
| ZA (1) | ZA937633B (no) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9407447D0 (en) * | 1994-04-14 | 1994-06-08 | Glaxo Group Ltd | Chemical compounds |
| EP0759918A1 (en) * | 1994-05-19 | 1997-03-05 | MERCK SHARP & DOHME LTD. | Piperazine, piperidine and tetrahydropyridine derivatives of indol-3-ylalkyl as 5-ht1d-alpha agonists |
| GB9610979D0 (en) * | 1996-05-24 | 1996-07-31 | Merck Sharp & Dohme | Therapeutic agents |
| AU4652697A (en) * | 1996-10-08 | 1998-05-05 | Eli Lilly And Company | New serotonin 5-ht1f agonists |
| US5891885A (en) * | 1996-10-09 | 1999-04-06 | Algos Pharmaceutical Corporation | Method for treating migraine |
| US20030198669A1 (en) * | 2001-07-05 | 2003-10-23 | R.T. Alamo Ventures I, Llc | Compositions and methods for rapid dissolving formulations of dihydroergotamine and caffeine for the treatment of migraine |
| US6685951B2 (en) | 2001-07-05 | 2004-02-03 | R. T. Alamo Ventures I, Inc. | Administration of dihydroergotamine as a sublingual spray or aerosol for the treatment of migraine |
| US20030017175A1 (en) * | 2001-07-05 | 2003-01-23 | R.T. Alamo Ventures I, Inc. | Sublingual administration of dihydroergotamine for the treatment of migraine |
| PL2734634T3 (pl) | 2011-07-22 | 2020-03-31 | The University Of Chicago | Igf-1 do zastosowania do leczenia migreny |
| KR101443041B1 (ko) * | 2013-05-06 | 2014-09-23 | (주)하이레벤 | 태양광 발전설비의 효율향상설비 |
| KR20240058859A (ko) | 2021-08-12 | 2024-05-03 | 쿨레온 엘엘씨 | 환각성 및 비환각성 세로토닌 수용체 작용제 및 이의 제조 및 사용 방법 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1670105A1 (de) * | 1966-07-08 | 1970-12-10 | Byk Gulden Lomberg Chem Fab | Verfahren zur Herstellung von Benzofuryl (3)-alkylaminen und deren Salzen |
| EP0398413A1 (en) * | 1989-05-16 | 1990-11-22 | Duphar International Research B.V | "3,4-dehydropiperidine derivatives having psychotropic activity |
-
1992
- 1992-10-16 GB GB929221761A patent/GB9221761D0/en active Pending
-
1993
- 1993-10-11 IS IS4081A patent/IS4081A/is unknown
- 1993-10-14 AU AU53337/94A patent/AU5333794A/en not_active Abandoned
- 1993-10-14 PL PL93308357A patent/PL308357A1/xx unknown
- 1993-10-14 US US08/406,981 patent/US5494910A/en not_active Expired - Fee Related
- 1993-10-14 RU RU95110110/04A patent/RU95110110A/ru unknown
- 1993-10-14 MX MX9306394A patent/MX9306394A/es unknown
- 1993-10-14 CZ CZ95968A patent/CZ96895A3/cs unknown
- 1993-10-14 HU HU9501073A patent/HUT72752A/hu unknown
- 1993-10-14 ZA ZA937633A patent/ZA937633B/xx unknown
- 1993-10-14 KR KR1019930021263A patent/KR940009179A/ko not_active Application Discontinuation
- 1993-10-14 WO PCT/EP1993/002833 patent/WO1994008993A1/en not_active Application Discontinuation
- 1993-10-14 CA CA002146569A patent/CA2146569A1/en not_active Abandoned
- 1993-10-14 EP EP93923463A patent/EP0664804A1/en not_active Withdrawn
- 1993-10-15 SI SI9300542A patent/SI9300542A/sl unknown
- 1993-10-15 IL IL107302A patent/IL107302A0/xx unknown
- 1993-10-15 JP JP5258631A patent/JPH06211842A/ja active Pending
- 1993-10-15 CN CN93115016A patent/CN1092420A/zh active Pending
- 1993-10-15 AP APAP/P/1993/000581A patent/AP425A/en active
- 1993-11-04 TW TW082108174A patent/TW262473B/zh active
-
1994
- 1994-03-02 EC EC1994001050A patent/ECSP941050A/es unknown
- 1994-04-13 PE PE1994240029A patent/PE51294A1/es not_active Application Discontinuation
-
1995
- 1995-04-12 NO NO951433A patent/NO951433D0/no unknown
- 1995-04-13 FI FI951798A patent/FI951798A/fi unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AP9300581A0 (en) | 1993-10-31 |
| US5494910A (en) | 1996-02-27 |
| MX9306394A (es) | 1994-05-31 |
| HU9501073D0 (en) | 1995-06-28 |
| RU95110110A (ru) | 1996-12-27 |
| CA2146569A1 (en) | 1994-04-28 |
| HUT72752A (en) | 1996-05-28 |
| KR940009179A (ko) | 1994-05-20 |
| WO1994008993A1 (en) | 1994-04-28 |
| SI9300542A (en) | 1994-06-30 |
| PE51294A1 (es) | 1995-01-06 |
| TW262473B (no) | 1995-11-11 |
| IS4081A (is) | 1994-04-17 |
| FI951798A0 (fi) | 1995-04-13 |
| PL308357A1 (en) | 1995-07-24 |
| AU5333794A (en) | 1994-05-09 |
| ZA937633B (en) | 1994-08-01 |
| JPH06211842A (ja) | 1994-08-02 |
| IL107302A0 (en) | 1994-01-25 |
| FI951798A (fi) | 1995-04-13 |
| GB9221761D0 (en) | 1992-12-02 |
| EP0664804A1 (en) | 1995-08-02 |
| CN1092420A (zh) | 1994-09-21 |
| CZ96895A3 (en) | 1995-12-13 |
| NO951433D0 (no) | 1995-04-12 |
| ECSP941050A (es) | 1994-11-16 |
| AP425A (en) | 1995-11-08 |
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