ZM2892A1 - Imidazo (1,2-a) (pyrrolo thieno or furano) (3,2-d) azepine derivatives compositions and method of use - Google Patents

Imidazo (1,2-a) (pyrrolo thieno or furano) (3,2-d) azepine derivatives compositions and method of use

Info

Publication number
ZM2892A1
ZM2892A1 ZM2892A ZM2892A ZM2892A1 ZM 2892 A1 ZM2892 A1 ZM 2892A1 ZM 2892 A ZM2892 A ZM 2892A ZM 2892 A ZM2892 A ZM 2892A ZM 2892 A1 ZM2892 A1 ZM 2892A1
Authority
ZM
Zambia
Prior art keywords
4alkyl
substituted
hydroxycarbonyl
represents hydrogen
4alkyloxy
Prior art date
Application number
ZM2892A
Other languages
English (en)
Inventor
Frans Eduard Janssens
Gaston Stanielas
Marcella Diels
Joseph Elisabeth Leenaerts
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of ZM2892A1 publication Critical patent/ZM2892A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
    • C07D491/14—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D495/14—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pulmonology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Paper (AREA)
  • Detergent Compositions (AREA)
  • Fats And Perfumes (AREA)
  • Lubricants (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
ZM2892A 1991-06-13 1992-06-12 Imidazo (1,2-a) (pyrrolo thieno or furano) (3,2-d) azepine derivatives compositions and method of use ZM2892A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US71448791A 1991-06-13 1991-06-13

Publications (1)

Publication Number Publication Date
ZM2892A1 true ZM2892A1 (en) 1994-05-25

Family

ID=24870247

Family Applications (1)

Application Number Title Priority Date Filing Date
ZM2892A ZM2892A1 (en) 1991-06-13 1992-06-12 Imidazo (1,2-a) (pyrrolo thieno or furano) (3,2-d) azepine derivatives compositions and method of use

Country Status (26)

Country Link
US (1) US5461050A (ko)
EP (2) EP0588859B1 (ko)
JP (1) JP3182421B2 (ko)
KR (1) KR100247504B1 (ko)
CN (1) CN1033587C (ko)
AT (1) ATE247118T1 (ko)
AU (1) AU652841B2 (ko)
CA (1) CA2102889C (ko)
DE (1) DE69233161T2 (ko)
ES (1) ES2204892T3 (ko)
FI (1) FI104077B (ko)
HR (1) HRP920156A2 (ko)
HU (1) HU221013B1 (ko)
IE (1) IE921919A1 (ko)
IL (1) IL101851A (ko)
MA (1) MA22554A1 (ko)
MX (1) MX9202860A (ko)
NO (2) NO300689B1 (ko)
NZ (1) NZ242775A (ko)
PL (1) PL170376B1 (ko)
SI (1) SI9200104A (ko)
TN (1) TNSN92049A1 (ko)
TW (1) TW218382B (ko)
WO (1) WO1992022553A1 (ko)
ZA (1) ZA924327B (ko)
ZM (1) ZM2892A1 (ko)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL101850A (en) * 1991-06-13 1996-01-31 Janssen Pharmaceutica Nv History 11-) 4-Pipridinyl (-Imidazo] B-1, 2 [] 3 [Benzazepine, their preparation and pharmaceutical preparations containing them
GR1001385B (el) * 1992-10-12 1993-10-29 Janssen Pharmaceutica Nv Παράγωγα ιμιδαζο 1,2-α (πυρρολο,?ειενο η φουρανο) 3,2-d αζεπίνης συν?έσεις και μέ?οδοι χρήσεως.
KR100251295B1 (ko) * 1992-12-04 2000-05-01 디르크 반테 항앨러지성 이미다조[1,2-a](피롤로, 티에노 또는 푸라노)[2,3-d]아제핀 유도체(Antiallergic imidazo[1,2-a](pyrrolo, thieno or furano)[2,3-d]azepine derivatives)
JP3503065B2 (ja) * 1992-12-04 2004-03-02 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノート シヤツプ 抗アレルギー性トリアゾロ（ピロロ、チエノ又はフラノ）アゼピン誘導体
NZ271071A (en) * 1993-07-13 1996-08-27 Janssen Pharmaceutica Nv Aryl- or benzo-imidazoazepine derivatives {typically 7,10-dihydro-7-methyl-10-(1-methyl-4-piperidinylidene)imida zo[1,2-a]pyrrolo[3,2-d]-azepin-6(5h)-one}; intermediates including 1-esterified-2-[disubstitutedmethyl-1h-imidazole
TW382017B (en) * 1995-12-27 2000-02-11 Janssen Pharmaceutica Nv 1-(1,2-disubstituted piperidinyl)-4-(fused imidazole)-piperidine derivatives
TW527186B (en) 1996-03-19 2003-04-11 Janssen Pharmaceutica Nv Fused imidazole derivatives as multidrug resistance modulators
JP3882224B2 (ja) * 1996-05-31 2007-02-14 旭硝子株式会社 パロキセチンの製造方法
EP1011726B1 (en) 1997-09-18 2003-02-26 Janssen Pharmaceutica N.V. Fused imidazole derivatives for improving oral bioavailability of pharmaceutical agents
SK286158B6 (sk) * 1998-12-19 2008-04-07 Janssen Pharmaceutica N. V. Spirozlúčenina, spôsob a medziprodukt na jej prípravu, jej použitie, farmaceutická kompozícia s jejobsahom a spôsob jej prípravy
TWI225488B (en) * 1999-12-21 2004-12-21 Janssen Pharmaceutica Nv Derivatives of homopiperidinyl substituted benzimidazole analogues
EP1401838B1 (en) 2001-06-12 2014-03-26 Janssen Pharmaceutica NV Novel substituted tetracyclic imidazole derivatives, processes for their preparation, pharmaceutical compositions comprising them and their use as a medicine
KR20060052867A (ko) * 2003-07-23 2006-05-19 엑셀리시스, 인코포레이티드 약제로서의 아제핀 유도체
CN101137657B (zh) 2005-03-08 2011-02-02 詹森药业有限公司 作为神经激肽（nk1）拮抗剂的二氮杂-螺-[4.4]-壬烷衍生物
TWI498115B (zh) * 2007-12-27 2015-09-01 Daiichi Sankyo Co Ltd 咪唑羰基化合物
CN103570731B (zh) * 2012-07-30 2016-05-18 中国科学院广州生物医药与健康研究院 嘧啶并三环或嘧啶并四环类化合物及其药用组合物和应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4148903A (en) * 1977-07-28 1979-04-10 Merck & Co., Inc. Antipsychotic, antiserotonin and antihistaminic pyrrolo[2,1-b][3]benzazepines
GB8900380D0 (en) * 1989-01-09 1989-03-08 Janssen Pharmaceutica Nv 2-aminopyrimidinone derivatives
IL101850A (en) * 1991-06-13 1996-01-31 Janssen Pharmaceutica Nv History 11-) 4-Pipridinyl (-Imidazo] B-1, 2 [] 3 [Benzazepine, their preparation and pharmaceutical preparations containing them

Also Published As

Publication number Publication date
NZ242775A (en) 1995-03-28
TW218382B (ko) 1994-01-01
NO934493D0 (no) 1993-12-09
US5461050A (en) 1995-10-24
FI935557A0 (fi) 1993-12-10
FI104077B1 (fi) 1999-11-15
JPH06507890A (ja) 1994-09-08
HU9303554D0 (en) 1994-04-28
IL101851A (en) 1996-05-14
EP0588859A1 (en) 1994-03-30
NO934493L (no) 1994-01-04
HRP920156A2 (en) 1995-12-31
MA22554A1 (fr) 1992-12-31
AU1901192A (en) 1993-01-12
SI9200104A (en) 1992-12-31
IL101851A0 (en) 1992-12-30
FI935557A (fi) 1993-12-10
PL170376B1 (pl) 1996-12-31
CA2102889C (en) 2002-11-26
ES2204892T3 (es) 2004-05-01
HUT70428A (en) 1995-10-30
ZA924327B (en) 1993-12-13
KR100247504B1 (ko) 2000-05-01
EP0518434A1 (en) 1992-12-16
TNSN92049A1 (fr) 1993-06-08
MX9202860A (es) 1992-12-01
JP3182421B2 (ja) 2001-07-03
FI104077B (fi) 1999-11-15
DE69233161T2 (de) 2004-05-27
WO1992022553A1 (en) 1992-12-23
CN1068116A (zh) 1993-01-20
IE921919A1 (en) 1992-12-16
ATE247118T1 (de) 2003-08-15
HU221013B1 (hu) 2002-07-29
NO300689B1 (no) 1997-07-07
CA2102889A1 (en) 1992-12-14
AU652841B2 (en) 1994-09-08
EP0588859B1 (en) 2003-08-13
DE69233161D1 (de) 2003-09-18
CN1033587C (zh) 1996-12-18

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