IL101851A - History 01 -) 4 - Pipridinyl - and Pipridinylidene (- Imidazo] A-1,2 [Pirolo, Thiano or Purano (] 3,2 [Azpin, their preparation and pharmaceutical preparations containing them and composition - Google Patents
History 01 -) 4 - Pipridinyl - and Pipridinylidene (- Imidazo] A-1,2 [Pirolo, Thiano or Purano (] 3,2 [Azpin, their preparation and pharmaceutical preparations containing them and compositionInfo
- Publication number
- IL101851A IL101851A IL10185192A IL10185192A IL101851A IL 101851 A IL101851 A IL 101851A IL 10185192 A IL10185192 A IL 10185192A IL 10185192 A IL10185192 A IL 10185192A IL 101851 A IL101851 A IL 101851A
- Authority
- IL
- Israel
- Prior art keywords
- formula
- compound
- substituted
- alkyl
- reaction
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
- C07D487/14—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
- C07D491/14—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D495/14—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Pulmonology (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Paper (AREA)
- Detergent Compositions (AREA)
- Fats And Perfumes (AREA)
- Lubricants (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US71448791A | 1991-06-13 | 1991-06-13 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL101851A0 IL101851A0 (en) | 1992-12-30 |
| IL101851A true IL101851A (en) | 1996-05-14 |
Family
ID=24870247
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL10185192A IL101851A (en) | 1991-06-13 | 1992-05-13 | History 01 -) 4 - Pipridinyl - and Pipridinylidene (- Imidazo] A-1,2 [Pirolo, Thiano or Purano (] 3,2 [Azpin, their preparation and pharmaceutical preparations containing them and composition |
Country Status (26)
| Country | Link |
|---|---|
| US (1) | US5461050A (ko) |
| EP (2) | EP0588859B1 (ko) |
| JP (1) | JP3182421B2 (ko) |
| KR (1) | KR100247504B1 (ko) |
| CN (1) | CN1033587C (ko) |
| AT (1) | ATE247118T1 (ko) |
| AU (1) | AU652841B2 (ko) |
| CA (1) | CA2102889C (ko) |
| DE (1) | DE69233161T2 (ko) |
| ES (1) | ES2204892T3 (ko) |
| FI (1) | FI104077B (ko) |
| HR (1) | HRP920156A2 (ko) |
| HU (1) | HU221013B1 (ko) |
| IE (1) | IE921919A1 (ko) |
| IL (1) | IL101851A (ko) |
| MA (1) | MA22554A1 (ko) |
| MX (1) | MX9202860A (ko) |
| NO (2) | NO934493D0 (ko) |
| NZ (1) | NZ242775A (ko) |
| PL (1) | PL170376B1 (ko) |
| SI (1) | SI9200104A (ko) |
| TN (1) | TNSN92049A1 (ko) |
| TW (1) | TW218382B (ko) |
| WO (1) | WO1992022553A1 (ko) |
| ZA (1) | ZA924327B (ko) |
| ZM (1) | ZM2892A1 (ko) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL101850A (en) * | 1991-06-13 | 1996-01-31 | Janssen Pharmaceutica Nv | History 11-) 4-Pipridinyl (-Imidazo] B-1, 2 [] 3 [Benzazepine, their preparation and pharmaceutical preparations containing them |
| GR1001385B (el) * | 1992-10-12 | 1993-10-29 | Janssen Pharmaceutica Nv | Παράγωγα ιμιδαζο 1,2-α (πυρρολο,?ειενο η φουρανο) 3,2-d αζεπίνης συν?έσεις και μέ?οδοι χρήσεως. |
| CA2150805C (en) * | 1992-12-04 | 2006-08-15 | Frans Eduard Janssens | Antiallergic imidazo[1,2-a](pyrrolo, thieno or furano)[2,3-d]azepine derivatives |
| RU2127737C1 (ru) * | 1992-12-04 | 1999-03-20 | Жансен Фармасетика Н.В. | Производные триазоло-(пирроло-тиено- или фурано-)-азепина, обладающие антиаллергической активностью, способ их получения, промежуточное для их получения, фармацевтическая композиция и способ ее получения |
| US5674866A (en) * | 1993-07-13 | 1997-10-07 | Janssen Pharmaceutica N.V. | Antiallergic imidazoazepines |
| TW382017B (en) | 1995-12-27 | 2000-02-11 | Janssen Pharmaceutica Nv | 1-(1,2-disubstituted piperidinyl)-4-(fused imidazole)-piperidine derivatives |
| TW527186B (en) | 1996-03-19 | 2003-04-11 | Janssen Pharmaceutica Nv | Fused imidazole derivatives as multidrug resistance modulators |
| JP3882224B2 (ja) * | 1996-05-31 | 2007-02-14 | 旭硝子株式会社 | パロキセチンの製造方法 |
| AU1146099A (en) * | 1997-09-18 | 1999-04-05 | Janssen Pharmaceutica N.V. | Fused imidazole derivatives for improving oral bioavailability of pharmaceuticalagents |
| SK286158B6 (sk) * | 1998-12-19 | 2008-04-07 | Janssen Pharmaceutica N. V. | Spirozlúčenina, spôsob a medziprodukt na jej prípravu, jej použitie, farmaceutická kompozícia s jejobsahom a spôsob jej prípravy |
| TWI225488B (en) * | 1999-12-21 | 2004-12-21 | Janssen Pharmaceutica Nv | Derivatives of homopiperidinyl substituted benzimidazole analogues |
| WO2002100862A2 (en) | 2001-06-12 | 2002-12-19 | Janssen Pharmaceutica N.V. | Novel substituted tetracyclic imidazole derivatives, processes for their preparation, pharmaceutical compositions comprising them and their use as a medicine |
| AU2004259009A1 (en) * | 2003-07-23 | 2005-02-03 | Exelixis, Inc. | Azepine derivatives as pharmaceutical agents |
| JP5078869B2 (ja) | 2005-03-08 | 2012-11-21 | ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ | ニューロキニン（ｎｋ１）拮抗物質としてのジアザ−スピロ−［４．４］−ノナン誘導体 |
| TWI498115B (zh) * | 2007-12-27 | 2015-09-01 | Daiichi Sankyo Co Ltd | 咪唑羰基化合物 |
| CN103570731B (zh) * | 2012-07-30 | 2016-05-18 | 中国科学院广州生物医药与健康研究院 | 嘧啶并三环或嘧啶并四环类化合物及其药用组合物和应用 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4148903A (en) * | 1977-07-28 | 1979-04-10 | Merck & Co., Inc. | Antipsychotic, antiserotonin and antihistaminic pyrrolo[2,1-b][3]benzazepines |
| GB8900380D0 (en) * | 1989-01-09 | 1989-03-08 | Janssen Pharmaceutica Nv | 2-aminopyrimidinone derivatives |
| IL101850A (en) * | 1991-06-13 | 1996-01-31 | Janssen Pharmaceutica Nv | History 11-) 4-Pipridinyl (-Imidazo] B-1, 2 [] 3 [Benzazepine, their preparation and pharmaceutical preparations containing them |
-
1992
- 1992-05-13 IL IL10185192A patent/IL101851A/en not_active IP Right Cessation
- 1992-05-15 NZ NZ242775A patent/NZ242775A/en unknown
- 1992-05-16 CN CN92104830A patent/CN1033587C/zh not_active Expired - Fee Related
- 1992-05-21 TW TW081103953A patent/TW218382B/zh active
- 1992-06-09 HU HU9303554A patent/HU221013B1/hu not_active IP Right Cessation
- 1992-06-09 EP EP92911643A patent/EP0588859B1/en not_active Expired - Lifetime
- 1992-06-09 WO PCT/EP1992/001331 patent/WO1992022553A1/en active IP Right Grant
- 1992-06-09 JP JP51073492A patent/JP3182421B2/ja not_active Expired - Fee Related
- 1992-06-09 US US08/150,121 patent/US5461050A/en not_active Expired - Lifetime
- 1992-06-09 EP EP92201665A patent/EP0518434A1/en active Pending
- 1992-06-09 CA CA002102889A patent/CA2102889C/en not_active Expired - Fee Related
- 1992-06-09 DE DE69233161T patent/DE69233161T2/de not_active Expired - Fee Related
- 1992-06-09 ES ES92911643T patent/ES2204892T3/es not_active Expired - Lifetime
- 1992-06-09 AT AT92911643T patent/ATE247118T1/de not_active IP Right Cessation
- 1992-06-09 KR KR1019930703789A patent/KR100247504B1/ko not_active IP Right Cessation
- 1992-06-09 PL PL92301819A patent/PL170376B1/pl unknown
- 1992-06-09 AU AU19011/92A patent/AU652841B2/en not_active Ceased
- 1992-06-10 HR HR920156A patent/HRP920156A2/hr not_active Application Discontinuation
- 1992-06-11 MA MA22844A patent/MA22554A1/fr unknown
- 1992-06-12 ZM ZM2892A patent/ZM2892A1/xx unknown
- 1992-06-12 ZA ZA924327A patent/ZA924327B/xx unknown
- 1992-06-12 MX MX9202860A patent/MX9202860A/es not_active IP Right Cessation
- 1992-06-12 SI SI19929200104A patent/SI9200104A/sl not_active IP Right Cessation
- 1992-06-15 TN TNTNSN92049A patent/TNSN92049A1/fr unknown
- 1992-07-01 IE IE191992A patent/IE921919A1/en not_active Application Discontinuation
-
1993
- 1993-12-09 NO NO934493D patent/NO934493D0/no unknown
- 1993-12-09 NO NO934493A patent/NO300689B1/no not_active IP Right Cessation
- 1993-12-10 FI FI935557A patent/FI104077B/fi active
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| EP0588858B1 (en) | IMIDAZO 2,1-b] 3]BENZAZEPINE DERIVATIVES, COMPOSITIONS AND METHOD OF USE | |
| IL101851A (en) | History 01 -) 4 - Pipridinyl - and Pipridinylidene (- Imidazo] A-1,2 [Pirolo, Thiano or Purano (] 3,2 [Azpin, their preparation and pharmaceutical preparations containing them and composition | |
| AU676702B2 (en) | Antiallergic imidazo{1,2-a}(pyrrolo, thieno or furano){2,3-d}azepine derivatives | |
| EP0708776B1 (en) | Antiallergic imidazoazepines | |
| US5595988A (en) | Triazolo(pyrrolo, thieno or furano)azepine derivatives | |
| CA2165800C (en) | Antiallergic imidazoazepines |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FF | Patent granted | ||
| KB | Patent renewed | ||
| KB | Patent renewed | ||
| KB | Patent renewed | ||
| MM9K | Patent not in force due to non-payment of renewal fees |