ZA991319B - Novel phthalimido arylpiperazines useful in the treatment of benign prostatic hyperplasia. - Google Patents

Novel phthalimido arylpiperazines useful in the treatment of benign prostatic hyperplasia.

Info

Publication number
ZA991319B
ZA991319B ZA9901319A ZA991319A ZA991319B ZA 991319 B ZA991319 B ZA 991319B ZA 9901319 A ZA9901319 A ZA 9901319A ZA 991319 A ZA991319 A ZA 991319A ZA 991319 B ZA991319 B ZA 991319B
Authority
ZA
South Africa
Prior art keywords
novel
treatment
benign prostatic
prostatic hyperplasia
phthalimido
Prior art date
Application number
ZA9901319A
Other languages
English (en)
Inventor
Gee-Hong Kuo
William V Murray
Catherine P Prouty
Original Assignee
Ortho Mcneil Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ortho Mcneil Pharm Inc filed Critical Ortho Mcneil Pharm Inc
Publication of ZA991319B publication Critical patent/ZA991319B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44Iso-indoles; Hydrogenated iso-indoles
    • C07D209/48Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/08Drugs for disorders of the urinary system of the prostate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/10Drugs for disorders of the urinary system of the bladder
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/24Drugs for disorders of the endocrine system of the sex hormones
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Indole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ZA9901319A 1998-02-20 1999-02-18 Novel phthalimido arylpiperazines useful in the treatment of benign prostatic hyperplasia. ZA991319B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US7551098P 1998-02-20 1998-02-20

Publications (1)

Publication Number Publication Date
ZA991319B true ZA991319B (en) 2000-11-20

Family

ID=22126243

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA9901319A ZA991319B (en) 1998-02-20 1999-02-18 Novel phthalimido arylpiperazines useful in the treatment of benign prostatic hyperplasia.

Country Status (21)

Country Link
US (2) US20020077476A1 (de)
EP (1) EP1056720B1 (de)
JP (1) JP2002503722A (de)
KR (1) KR100608473B1 (de)
CN (1) CN1172911C (de)
AR (1) AR015521A1 (de)
AT (1) ATE280156T1 (de)
AU (1) AU766411B2 (de)
BR (1) BR9908122A (de)
DE (1) DE69921300T2 (de)
ES (1) ES2233023T3 (de)
HK (1) HK1031872A1 (de)
HU (1) HUP0100704A3 (de)
IL (2) IL137953A0 (de)
NO (1) NO317104B1 (de)
NZ (1) NZ506461A (de)
PL (1) PL194649B1 (de)
PT (1) PT1056720E (de)
TR (1) TR200003224T2 (de)
WO (1) WO1999042445A1 (de)
ZA (1) ZA991319B (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITMI20010164A1 (it) * 2001-01-30 2002-07-30 Recordati Chem Pharm Alfa 1 antagonisti selettivi a + d
CN103387531A (zh) * 2012-05-10 2013-11-13 广州医学院 酰胺类芳基哌嗪衍生物及其制备方法和在抗良性前列腺增生中的应用
HUP1400294A2 (hu) 2014-06-13 2015-12-28 Skillpharm Kft Clopidogrel új alkalmazása
CN105061434B (zh) * 2015-07-30 2017-07-21 新发药业有限公司 一种西他列汀磷酸盐的制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1382742A (en) 1972-09-19 1975-02-05 Labaz Benzofuran derivatives and process for preparing the same
CH585693A5 (de) 1974-02-08 1977-03-15 Ciba Geigy Ag
HU177702B (en) 1977-10-24 1981-12-28 Noevenyvedelmi Kutato Intezet Plant growth regulator and process for preparing the active materials
PT82077B (fr) * 1985-02-26 1987-09-25 Sanofi Sa Procede pour l'obtention des derives aminoalcools peptidiques inhibiteurs de la renine et des proteases acides
FR2678271B1 (fr) * 1991-06-27 1995-01-13 Synthelabo Derives de pyrimidine-4-carboxamide, leur preparation et leur application en therapeutique.
US5428037A (en) * 1993-04-09 1995-06-27 Syntex Pharmaceuticals, Ltd. Heterocyclic derivatives in the treatment of Ischaemia and related diseases
EA001904B1 (ru) * 1997-05-12 2001-10-22 ОРТО МакНЕЙЛ ФАРМАСЬЮТИКАЛ, ИНК. Арилзамещенные пиперазины для лечения доброкачественной гиперплазии простаты

Also Published As

Publication number Publication date
HUP0100704A3 (en) 2002-10-28
HK1031872A1 (en) 2001-06-29
AU766411B2 (en) 2003-10-16
BR9908122A (pt) 2001-11-13
EP1056720B1 (de) 2004-10-20
CN1172911C (zh) 2004-10-27
JP2002503722A (ja) 2002-02-05
DE69921300D1 (de) 2004-11-25
CN1291185A (zh) 2001-04-11
ATE280156T1 (de) 2004-11-15
KR100608473B1 (ko) 2006-08-09
PL342357A1 (en) 2001-06-04
PL194649B1 (pl) 2007-06-29
US20020077476A1 (en) 2002-06-20
KR20010041118A (ko) 2001-05-15
US20030088099A1 (en) 2003-05-08
WO1999042445A1 (en) 1999-08-26
NZ506461A (en) 2003-08-29
IL137953A0 (en) 2001-10-31
ES2233023T3 (es) 2005-06-01
EP1056720A1 (de) 2000-12-06
PT1056720E (pt) 2005-02-28
AU2776599A (en) 1999-09-06
NO317104B1 (no) 2004-08-09
NO20004142L (no) 2000-10-19
HUP0100704A2 (hu) 2001-10-28
TR200003224T2 (tr) 2001-03-21
NO20004142D0 (no) 2000-08-18
US6780994B2 (en) 2004-08-24
IL137953A (en) 2006-12-31
DE69921300T2 (de) 2006-03-09
AR015521A1 (es) 2001-05-02

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