TR200003224T2 - İyi huylu prostat hiperplasianın tedavisinde alfa 1A reseptörü antagonistleri olarak yararlı olan ftalimido arilpiperazinler - Google Patents
İyi huylu prostat hiperplasianın tedavisinde alfa 1A reseptörü antagonistleri olarak yararlı olan ftalimido arilpiperazinlerInfo
- Publication number
- TR200003224T2 TR200003224T2 TR2000/03224T TR200003224T TR200003224T2 TR 200003224 T2 TR200003224 T2 TR 200003224T2 TR 2000/03224 T TR2000/03224 T TR 2000/03224T TR 200003224 T TR200003224 T TR 200003224T TR 200003224 T2 TR200003224 T2 TR 200003224T2
- Authority
- TR
- Turkey
- Prior art keywords
- alpha
- treatment
- benign prostatic
- prostatic hyperplasia
- useful
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/44—Iso-indoles; Hydrogenated iso-indoles
- C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Urology & Nephrology (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Indole Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Bu bulus bir ftalimido arilpiperazin türevleri serisi, bunlari içeren farmasötik bilesimler ve bunlarin yapiminda kullanilan islemler ve ara-bilesiklerle ilgilidir. Bulusun bilesikleri seçici olarak iyi huylu prostat hiperplasiada mevcut olan bir reseptör olan alfa 1a adrenerjik reseptörüne baglanmayi inhibe eder. Dolayisiyla bilesikler bu hastaligin tedavisinde potansiyel olarak yararlidir.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US7551098P | 1998-02-20 | 1998-02-20 |
Publications (1)
Publication Number | Publication Date |
---|---|
TR200003224T2 true TR200003224T2 (tr) | 2001-03-21 |
Family
ID=22126243
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TR2000/03224T TR200003224T2 (tr) | 1998-02-20 | 1999-02-19 | İyi huylu prostat hiperplasianın tedavisinde alfa 1A reseptörü antagonistleri olarak yararlı olan ftalimido arilpiperazinler |
Country Status (21)
Country | Link |
---|---|
US (2) | US20020077476A1 (tr) |
EP (1) | EP1056720B1 (tr) |
JP (1) | JP2002503722A (tr) |
KR (1) | KR100608473B1 (tr) |
CN (1) | CN1172911C (tr) |
AR (1) | AR015521A1 (tr) |
AT (1) | ATE280156T1 (tr) |
AU (1) | AU766411B2 (tr) |
BR (1) | BR9908122A (tr) |
DE (1) | DE69921300T2 (tr) |
ES (1) | ES2233023T3 (tr) |
HK (1) | HK1031872A1 (tr) |
HU (1) | HUP0100704A3 (tr) |
IL (2) | IL137953A0 (tr) |
NO (1) | NO317104B1 (tr) |
NZ (1) | NZ506461A (tr) |
PL (1) | PL194649B1 (tr) |
PT (1) | PT1056720E (tr) |
TR (1) | TR200003224T2 (tr) |
WO (1) | WO1999042445A1 (tr) |
ZA (1) | ZA991319B (tr) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ITMI20010164A1 (it) * | 2001-01-30 | 2002-07-30 | Recordati Chem Pharm | Alfa 1 antagonisti selettivi a + d |
CN103387531A (zh) * | 2012-05-10 | 2013-11-13 | 广州医学院 | 酰胺类芳基哌嗪衍生物及其制备方法和在抗良性前列腺增生中的应用 |
HUP1400294A2 (hu) | 2014-06-13 | 2015-12-28 | Skillpharm Kft | Clopidogrel új alkalmazása |
CN106966940B (zh) * | 2015-07-30 | 2019-03-19 | 新发药业有限公司 | 一种西他列汀磷酸盐中间体n-芳甲基-2s-氰基甲基吖啶的制备方法 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1382742A (en) | 1972-09-19 | 1975-02-05 | Labaz | Benzofuran derivatives and process for preparing the same |
CH585693A5 (tr) | 1974-02-08 | 1977-03-15 | Ciba Geigy Ag | |
HU177702B (en) | 1977-10-24 | 1981-12-28 | Noevenyvedelmi Kutato Intezet | Plant growth regulator and process for preparing the active materials |
PT82077B (fr) * | 1985-02-26 | 1987-09-25 | Sanofi Sa | Procede pour l'obtention des derives aminoalcools peptidiques inhibiteurs de la renine et des proteases acides |
FR2678271B1 (fr) * | 1991-06-27 | 1995-01-13 | Synthelabo | Derives de pyrimidine-4-carboxamide, leur preparation et leur application en therapeutique. |
US5428037A (en) * | 1993-04-09 | 1995-06-27 | Syntex Pharmaceuticals, Ltd. | Heterocyclic derivatives in the treatment of Ischaemia and related diseases |
DE69818255T2 (de) * | 1997-05-12 | 2004-12-23 | Ortho-Mcneil Pharmaceutical, Inc. | Arylsubstituierte piperazine die bei der behandlung von gutartiger prostatischer hyperlasie nützlich sind |
-
1999
- 1999-02-18 ZA ZA9901319A patent/ZA991319B/xx unknown
- 1999-02-19 PT PT99908303T patent/PT1056720E/pt unknown
- 1999-02-19 PL PL99342357A patent/PL194649B1/pl not_active IP Right Cessation
- 1999-02-19 WO PCT/US1999/003694 patent/WO1999042445A1/en active IP Right Grant
- 1999-02-19 ES ES99908303T patent/ES2233023T3/es not_active Expired - Lifetime
- 1999-02-19 BR BR9908122-9A patent/BR9908122A/pt not_active Application Discontinuation
- 1999-02-19 DE DE69921300T patent/DE69921300T2/de not_active Expired - Fee Related
- 1999-02-19 IL IL13795399A patent/IL137953A0/xx active IP Right Grant
- 1999-02-19 AT AT99908303T patent/ATE280156T1/de not_active IP Right Cessation
- 1999-02-19 HU HU0100704A patent/HUP0100704A3/hu unknown
- 1999-02-19 CN CNB998030260A patent/CN1172911C/zh not_active Expired - Fee Related
- 1999-02-19 EP EP99908303A patent/EP1056720B1/en not_active Expired - Lifetime
- 1999-02-19 AU AU27765/99A patent/AU766411B2/en not_active Ceased
- 1999-02-19 KR KR1020007009159A patent/KR100608473B1/ko not_active IP Right Cessation
- 1999-02-19 JP JP2000532397A patent/JP2002503722A/ja not_active Withdrawn
- 1999-02-19 TR TR2000/03224T patent/TR200003224T2/tr unknown
- 1999-02-19 NZ NZ506461A patent/NZ506461A/en unknown
- 1999-02-23 AR ARP990100676A patent/AR015521A1/es active IP Right Grant
-
2000
- 2000-08-18 NO NO20004142A patent/NO317104B1/no not_active IP Right Cessation
- 2000-08-18 IL IL137953A patent/IL137953A/en not_active IP Right Cessation
-
2001
- 2001-04-03 HK HK01102397A patent/HK1031872A1/xx not_active IP Right Cessation
- 2001-12-11 US US10/014,979 patent/US20020077476A1/en not_active Abandoned
-
2002
- 2002-07-29 US US10/207,473 patent/US6780994B2/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
AU766411B2 (en) | 2003-10-16 |
CN1172911C (zh) | 2004-10-27 |
ZA991319B (en) | 2000-11-20 |
US20030088099A1 (en) | 2003-05-08 |
EP1056720B1 (en) | 2004-10-20 |
US20020077476A1 (en) | 2002-06-20 |
NO20004142L (no) | 2000-10-19 |
HUP0100704A2 (hu) | 2001-10-28 |
DE69921300D1 (de) | 2004-11-25 |
BR9908122A (pt) | 2001-11-13 |
AR015521A1 (es) | 2001-05-02 |
US6780994B2 (en) | 2004-08-24 |
EP1056720A1 (en) | 2000-12-06 |
WO1999042445A1 (en) | 1999-08-26 |
KR20010041118A (ko) | 2001-05-15 |
IL137953A (en) | 2006-12-31 |
HK1031872A1 (en) | 2001-06-29 |
KR100608473B1 (ko) | 2006-08-09 |
CN1291185A (zh) | 2001-04-11 |
ATE280156T1 (de) | 2004-11-15 |
DE69921300T2 (de) | 2006-03-09 |
PL194649B1 (pl) | 2007-06-29 |
HUP0100704A3 (en) | 2002-10-28 |
NO20004142D0 (no) | 2000-08-18 |
AU2776599A (en) | 1999-09-06 |
IL137953A0 (en) | 2001-10-31 |
PT1056720E (pt) | 2005-02-28 |
PL342357A1 (en) | 2001-06-04 |
NO317104B1 (no) | 2004-08-09 |
NZ506461A (en) | 2003-08-29 |
ES2233023T3 (es) | 2005-06-01 |
JP2002503722A (ja) | 2002-02-05 |
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