ZA989450B - Novel use of compounds for anti-pruritic activity - Google Patents

Novel use of compounds for anti-pruritic activity

Info

Publication number
ZA989450B
ZA989450B ZA989450A ZA989450A ZA989450B ZA 989450 B ZA989450 B ZA 989450B ZA 989450 A ZA989450 A ZA 989450A ZA 989450 A ZA989450 A ZA 989450A ZA 989450 B ZA989450 B ZA 989450B
Authority
ZA
South Africa
Prior art keywords
compounds
novel use
pruritic activity
pruritic
activity
Prior art date
Application number
ZA989450A
Other languages
English (en)
Inventor
Don E Griswold
Siegfried B Christensen Iv
Original Assignee
Smithkline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Corp filed Critical Smithkline Beecham Corp
Publication of ZA989450B publication Critical patent/ZA989450B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A61K31/522—Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/04—Antipruritics

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dermatology (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
ZA989450A 1997-10-17 1998-10-16 Novel use of compounds for anti-pruritic activity ZA989450B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US6374697P 1997-10-17 1997-10-17

Publications (1)

Publication Number Publication Date
ZA989450B true ZA989450B (en) 1999-04-19

Family

ID=22051225

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA989450A ZA989450B (en) 1997-10-17 1998-10-16 Novel use of compounds for anti-pruritic activity

Country Status (18)

Country Link
EP (1) EP1030666A4 (de)
JP (1) JP2001520196A (de)
KR (1) KR20010031149A (de)
CN (1) CN1306426A (de)
AR (1) AR015966A1 (de)
AU (1) AU740875B2 (de)
BR (1) BR9814080A (de)
CA (1) CA2306985A1 (de)
CO (1) CO4810374A1 (de)
CZ (1) CZ20001376A3 (de)
HU (1) HUP0003792A3 (de)
IL (1) IL135581A0 (de)
NO (1) NO20001847L (de)
NZ (1) NZ503551A (de)
PL (1) PL341062A1 (de)
TR (1) TR200001040T2 (de)
WO (1) WO1999020280A1 (de)
ZA (1) ZA989450B (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUP0401305A2 (hu) 2001-01-31 2004-10-28 Pfizer Products Inc. Tiazolil-, oxazolil-, pirrolil- és imidazolil-savamid-származékok, mint PDE4 izozimek inhibitorai és az ezeket tartalmazó gyógyszerkészítmények
JP2004520386A (ja) 2001-01-31 2004-07-08 ファイザー・プロダクツ・インク Ｐｄｅ４アイソザイムの阻害剤として有用なニコチンアミドビアリール誘導体
PL364910A1 (en) 2001-01-31 2004-12-27 Pfizer Products Inc. Ether derivatives useful as inhibitors of pde4 isozymes
US7250518B2 (en) 2001-01-31 2007-07-31 Pfizer Inc. Nicotinamide acids, amides, and their mimetics active as inhibitors of PDE4 isozymes
US20030175314A1 (en) * 2001-11-19 2003-09-18 Didriksen Erik Johannes Pharmaceutical composition for dermal application
TW200503709A (en) * 2003-07-17 2005-02-01 Santen Pharmaceutical Co Ltd Itching treating agent containing piperidine derivative as active ingredient
WO2005053672A1 (ja) * 2003-12-04 2005-06-16 Santen Pharmaceutical Co., Ltd. シロミラストまたはその塩を有効成分とする掻痒治療剤
JP2005187458A (ja) * 2003-12-04 2005-07-14 Santen Pharmaceut Co Ltd シロミラストまたはその塩を有効成分とする掻痒治療剤
US7713982B2 (en) 2004-02-14 2010-05-11 Smithkline Beecham Corporation Xanthines with HM74A receptor activity
JP2008137892A (ja) * 2005-03-04 2008-06-19 Eisai Co Ltd 止痒剤
AR055369A1 (es) 2005-08-10 2007-08-22 Smithkline Beecham Corp Compuestos derivados de xantina, su uso para preparar un medicamento para el tratamiento de una enfermedad mediada por el receptor hm74a, formulaciones y combinacion farmaceuticas que la comprenden y metodo de preparacion de los mismos
MX2008010774A (es) * 2006-02-21 2008-09-01 Eisai R&D Man Co Ltd Derivados de 4-(3-benzoilaminofenil)-6, 7-dimetoxi-2-metilaminoqui nazolina.
TWI404709B (zh) * 2006-02-21 2013-08-11 Eisai R&D Man Co Ltd 4- (3-benzamidophenyl) -6,7-dimethoxy-2-methylamine quinazoline derivatives
EP2123641A4 (de) 2007-02-16 2011-06-22 Eisai R&D Man Co Ltd Kristall, amorphe form und salt von methyl n-[3-(6,7-dimethoxy- 2-methylaminochinazolin-4-yl)phenyl]terephthalamsäure
JP5060561B2 (ja) 2007-08-17 2012-10-31 エーザイ・アール・アンド・ディー・マネジメント株式会社 新規外用剤
US8492543B2 (en) 2007-08-17 2013-07-23 Eisai R&D Management Co., Ltd. Method for producing quinazoline derivative
US20140121240A1 (en) * 2011-06-28 2014-05-01 Maruho Co., Ltd. Novel pharmaceutical composition
SI3251675T1 (sl) 2015-01-30 2021-08-31 Shanton Pharma Pte. Ltd. Preprečevanje ali zdravljenje sečnokislinske ali protinske bolezni

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR930703319A (ko) * 1990-12-21 1993-11-29 데이빗 로버츠 키산틴 유도체
ATE224386T1 (de) * 1996-03-26 2002-10-15 Altana Pharma Ag Neue in 6-position substituierte phenanthridine
ES2187775T3 (es) * 1996-05-15 2003-06-16 Altana Pharma Ag Imidazopiridinas.
AU6825898A (en) * 1997-03-07 1998-09-29 Byk Gulden Lomberg Chemische Fabrik Gmbh Novel tetrazoles
CN1269722A (zh) * 1997-03-18 2000-10-11 Basf公司 调节对皮质类固醇反应的方法及组合物
US6384047B1 (en) * 1997-06-03 2002-05-07 Byk Gulden Lomberg Chemische Fabrik Gmbh Benzonaphthyridine

Also Published As

Publication number Publication date
NO20001847D0 (no) 2000-04-10
HUP0003792A3 (en) 2001-12-28
WO1999020280A1 (en) 1999-04-29
EP1030666A1 (de) 2000-08-30
TR200001040T2 (tr) 2001-01-22
NZ503551A (en) 2002-05-31
AU740875B2 (en) 2001-11-15
CO4810374A1 (es) 1999-06-30
IL135581A0 (en) 2001-05-20
PL341062A1 (en) 2001-03-26
CZ20001376A3 (cs) 2002-06-12
EP1030666A4 (de) 2002-10-16
AR015966A1 (es) 2001-05-30
AU1093899A (en) 1999-05-10
HUP0003792A2 (hu) 2001-10-28
NO20001847L (no) 2000-04-10
JP2001520196A (ja) 2001-10-30
BR9814080A (pt) 2000-09-26
KR20010031149A (ko) 2001-04-16
CN1306426A (zh) 2001-08-01
CA2306985A1 (en) 1999-04-29

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