EP1030666A4 - Neue verwendung von verbindungen mit anti-juck wirkung - Google Patents
Neue verwendung von verbindungen mit anti-juck wirkungInfo
- Publication number
- EP1030666A4 EP1030666A4 EP98953608A EP98953608A EP1030666A4 EP 1030666 A4 EP1030666 A4 EP 1030666A4 EP 98953608 A EP98953608 A EP 98953608A EP 98953608 A EP98953608 A EP 98953608A EP 1030666 A4 EP1030666 A4 EP 1030666A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- compounds
- novel use
- pruritic activity
- pruritic
- activity
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
- A61K31/522—Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US6374697P | 1997-10-17 | 1997-10-17 | |
US63746P | 1997-10-17 | ||
PCT/US1998/021886 WO1999020280A1 (en) | 1997-10-17 | 1998-10-16 | Novel use of compounds for anti-pruritic activity |
Publications (2)
Publication Number | Publication Date |
---|---|
EP1030666A1 EP1030666A1 (de) | 2000-08-30 |
EP1030666A4 true EP1030666A4 (de) | 2002-10-16 |
Family
ID=22051225
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP98953608A Withdrawn EP1030666A4 (de) | 1997-10-17 | 1998-10-16 | Neue verwendung von verbindungen mit anti-juck wirkung |
Country Status (18)
Country | Link |
---|---|
EP (1) | EP1030666A4 (de) |
JP (1) | JP2001520196A (de) |
KR (1) | KR20010031149A (de) |
CN (1) | CN1306426A (de) |
AR (1) | AR015966A1 (de) |
AU (1) | AU740875B2 (de) |
BR (1) | BR9814080A (de) |
CA (1) | CA2306985A1 (de) |
CO (1) | CO4810374A1 (de) |
CZ (1) | CZ20001376A3 (de) |
HU (1) | HUP0003792A3 (de) |
IL (1) | IL135581A0 (de) |
NO (1) | NO20001847L (de) |
NZ (1) | NZ503551A (de) |
PL (1) | PL341062A1 (de) |
TR (1) | TR200001040T2 (de) |
WO (1) | WO1999020280A1 (de) |
ZA (1) | ZA989450B (de) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PL364910A1 (en) | 2001-01-31 | 2004-12-27 | Pfizer Products Inc. | Ether derivatives useful as inhibitors of pde4 isozymes |
EE200300362A (et) | 2001-01-31 | 2003-12-15 | Pfizer Products Inc. | PDE4 isosüümide inhibiitoritena kasutatavad tiasolüül-, oksasolüül-, pürrolüül- ja imidasolüülhappeamiidi derivaadid |
IL156413A0 (en) | 2001-01-31 | 2004-01-04 | Pfizer Prod Inc | Nicotinamide biaryl derivatives useful as inhibitors of pde4 isozymes |
US7250518B2 (en) | 2001-01-31 | 2007-07-31 | Pfizer Inc. | Nicotinamide acids, amides, and their mimetics active as inhibitors of PDE4 isozymes |
US20030175314A1 (en) * | 2001-11-19 | 2003-09-18 | Didriksen Erik Johannes | Pharmaceutical composition for dermal application |
EP1647274A4 (de) * | 2003-07-17 | 2008-12-10 | Ono Pharmaceutical Co | Mittel zur behandlung von pruritus mit einem piperidin-derivat als wirkstoff |
JP2005187458A (ja) * | 2003-12-04 | 2005-07-14 | Santen Pharmaceut Co Ltd | シロミラストまたはその塩を有効成分とする掻痒治療剤 |
WO2005053672A1 (ja) * | 2003-12-04 | 2005-06-16 | Santen Pharmaceutical Co., Ltd. | シロミラストまたはその塩を有効成分とする掻痒治療剤 |
NZ548496A (en) * | 2004-02-14 | 2010-02-26 | Smithkline Beecham Corp | Medicaments with HM74A receptor activity for disorder of lipid metabolism |
JP2008137892A (ja) * | 2005-03-04 | 2008-06-19 | Eisai Co Ltd | 止痒剤 |
ATE487719T1 (de) | 2005-08-10 | 2010-11-15 | Glaxosmithkline Llc | Xanthinderivate als selektive hm74a-agonisten |
WO2007097317A1 (ja) * | 2006-02-21 | 2007-08-30 | Eisai R & D Management Co., Ltd. | 4-(3-ベンゾイルアミノフェニル)-6,7-ジメトキシ-2-メチルアミノキナゾリン誘導体 |
TWI404709B (zh) * | 2006-02-21 | 2013-08-11 | Eisai R&D Man Co Ltd | 4- (3-benzamidophenyl) -6,7-dimethoxy-2-methylamine quinazoline derivatives |
WO2008099887A1 (ja) | 2007-02-16 | 2008-08-21 | Eisai R & D Management Co., Ltd. | メチル n-[3-(6,7-ジメトキシ-2-メチルアミノキナゾリン-4-イル)フェニル]テレフタラミックアシッドの結晶、非晶質体または塩 |
EP2189450B1 (de) | 2007-08-17 | 2011-12-21 | Eisai R&D Management Co., Ltd. | Verfahren zur herstellung eines chinazolinderivats |
JP5060561B2 (ja) | 2007-08-17 | 2012-10-31 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | 新規外用剤 |
EP2727594B1 (de) | 2011-06-28 | 2017-12-20 | Mitsubishi Tanabe Pharma Corporation | Naphtalene verbindungen zur behandlung von juckreiz |
PT3251675T (pt) | 2015-01-30 | 2021-05-25 | Shanton Pharma Pte Ltd | Prevenção ou tratamento de doença de ácido úrico ou gota |
Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1997035854A1 (de) * | 1996-03-26 | 1997-10-02 | Byk Gulden Lomberg Chemische Fabrik Gmbh | Neue in 6-position substituierte phenanthridine |
WO1997043288A1 (en) * | 1996-05-15 | 1997-11-20 | Byk Gulden Lomberg Chemische Fabrik Gmbh | Novel imidazopyridines |
WO1998040382A1 (en) * | 1997-03-07 | 1998-09-17 | Byk Gulden Lomberg Chemische Fabrik Gmbh | Novel tetrazoles |
WO1998041232A2 (en) * | 1997-03-18 | 1998-09-24 | Basf Aktiengesellschaft | Compositions for modulating responsiveness to corticosteroids |
WO1998055481A1 (en) * | 1997-06-03 | 1998-12-10 | Byk Gulden Lomberg Chemische Fabrik Gmbh | Benzonaphthyridine |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE194345T1 (de) * | 1990-12-21 | 2000-07-15 | Beecham Group Plc | Xanthinderivate |
-
1998
- 1998-10-15 AR ARP980105131A patent/AR015966A1/es not_active Application Discontinuation
- 1998-10-16 EP EP98953608A patent/EP1030666A4/de not_active Withdrawn
- 1998-10-16 CN CN98810066A patent/CN1306426A/zh active Pending
- 1998-10-16 AU AU10938/99A patent/AU740875B2/en not_active Ceased
- 1998-10-16 CA CA002306985A patent/CA2306985A1/en not_active Abandoned
- 1998-10-16 JP JP2000516677A patent/JP2001520196A/ja not_active Withdrawn
- 1998-10-16 IL IL13558198A patent/IL135581A0/xx unknown
- 1998-10-16 TR TR2000/01040T patent/TR200001040T2/xx unknown
- 1998-10-16 CO CO98060225A patent/CO4810374A1/es unknown
- 1998-10-16 WO PCT/US1998/021886 patent/WO1999020280A1/en not_active Application Discontinuation
- 1998-10-16 BR BR9814080-9A patent/BR9814080A/pt not_active IP Right Cessation
- 1998-10-16 PL PL98341062A patent/PL341062A1/xx unknown
- 1998-10-16 HU HU0003792A patent/HUP0003792A3/hu unknown
- 1998-10-16 ZA ZA989450A patent/ZA989450B/xx unknown
- 1998-10-16 CZ CZ20001376A patent/CZ20001376A3/cs unknown
- 1998-10-16 NZ NZ503551A patent/NZ503551A/en unknown
- 1998-10-16 KR KR1020007004053A patent/KR20010031149A/ko not_active Application Discontinuation
-
2000
- 2000-04-10 NO NO20001847A patent/NO20001847L/no not_active Application Discontinuation
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1997035854A1 (de) * | 1996-03-26 | 1997-10-02 | Byk Gulden Lomberg Chemische Fabrik Gmbh | Neue in 6-position substituierte phenanthridine |
WO1997043288A1 (en) * | 1996-05-15 | 1997-11-20 | Byk Gulden Lomberg Chemische Fabrik Gmbh | Novel imidazopyridines |
WO1998040382A1 (en) * | 1997-03-07 | 1998-09-17 | Byk Gulden Lomberg Chemische Fabrik Gmbh | Novel tetrazoles |
WO1998041232A2 (en) * | 1997-03-18 | 1998-09-24 | Basf Aktiengesellschaft | Compositions for modulating responsiveness to corticosteroids |
WO1998055481A1 (en) * | 1997-06-03 | 1998-12-10 | Byk Gulden Lomberg Chemische Fabrik Gmbh | Benzonaphthyridine |
Non-Patent Citations (3)
Title |
---|
DATABASE CA [online] CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; COHAN, V. L. ET AL: "In vitro pharmacology of the novel phosphodiesterase type 4 inhibitor, CP - 80633", XP002210532, retrieved from STN Database accession no. 125:237990 CA * |
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (1996), 278(3), 1356-1361, 1996 * |
See also references of WO9920280A1 * |
Also Published As
Publication number | Publication date |
---|---|
CA2306985A1 (en) | 1999-04-29 |
NO20001847D0 (no) | 2000-04-10 |
PL341062A1 (en) | 2001-03-26 |
CZ20001376A3 (cs) | 2002-06-12 |
AU1093899A (en) | 1999-05-10 |
EP1030666A1 (de) | 2000-08-30 |
BR9814080A (pt) | 2000-09-26 |
TR200001040T2 (tr) | 2001-01-22 |
NZ503551A (en) | 2002-05-31 |
WO1999020280A1 (en) | 1999-04-29 |
IL135581A0 (en) | 2001-05-20 |
KR20010031149A (ko) | 2001-04-16 |
HUP0003792A3 (en) | 2001-12-28 |
AU740875B2 (en) | 2001-11-15 |
ZA989450B (en) | 1999-04-19 |
AR015966A1 (es) | 2001-05-30 |
CO4810374A1 (es) | 1999-06-30 |
JP2001520196A (ja) | 2001-10-30 |
HUP0003792A2 (hu) | 2001-10-28 |
NO20001847L (no) | 2000-04-10 |
CN1306426A (zh) | 2001-08-01 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 20000508 |
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AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE |
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AX | Request for extension of the european patent |
Free format text: SI PAYMENT 20000508 |
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A4 | Supplementary search report drawn up and despatched |
Effective date: 20020902 |
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AK | Designated contracting states |
Kind code of ref document: A4 Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE |
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STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
18D | Application deemed to be withdrawn |
Effective date: 20040503 |