EP1030666A4 - Neue verwendung von verbindungen mit anti-juck wirkung - Google Patents

Neue verwendung von verbindungen mit anti-juck wirkung

Info

Publication number
EP1030666A4
EP1030666A4 EP98953608A EP98953608A EP1030666A4 EP 1030666 A4 EP1030666 A4 EP 1030666A4 EP 98953608 A EP98953608 A EP 98953608A EP 98953608 A EP98953608 A EP 98953608A EP 1030666 A4 EP1030666 A4 EP 1030666A4
Authority
EP
European Patent Office
Prior art keywords
compounds
novel use
pruritic activity
pruritic
activity
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP98953608A
Other languages
English (en)
French (fr)
Other versions
EP1030666A1 (de
Inventor
Don E Griswold
Siegfried Benjamin Christensen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Ltd
Original Assignee
SmithKline Beecham Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SmithKline Beecham Ltd filed Critical SmithKline Beecham Ltd
Publication of EP1030666A1 publication Critical patent/EP1030666A1/de
Publication of EP1030666A4 publication Critical patent/EP1030666A4/de
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A61K31/522—Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/04—Antipruritics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
EP98953608A 1997-10-17 1998-10-16 Neue verwendung von verbindungen mit anti-juck wirkung Withdrawn EP1030666A4 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US6374697P 1997-10-17 1997-10-17
US63746P 1997-10-17
PCT/US1998/021886 WO1999020280A1 (en) 1997-10-17 1998-10-16 Novel use of compounds for anti-pruritic activity

Publications (2)

Publication Number Publication Date
EP1030666A1 EP1030666A1 (de) 2000-08-30
EP1030666A4 true EP1030666A4 (de) 2002-10-16

Family

ID=22051225

Family Applications (1)

Application Number Title Priority Date Filing Date
EP98953608A Withdrawn EP1030666A4 (de) 1997-10-17 1998-10-16 Neue verwendung von verbindungen mit anti-juck wirkung

Country Status (18)

Country Link
EP (1) EP1030666A4 (de)
JP (1) JP2001520196A (de)
KR (1) KR20010031149A (de)
CN (1) CN1306426A (de)
AR (1) AR015966A1 (de)
AU (1) AU740875B2 (de)
BR (1) BR9814080A (de)
CA (1) CA2306985A1 (de)
CO (1) CO4810374A1 (de)
CZ (1) CZ20001376A3 (de)
HU (1) HUP0003792A3 (de)
IL (1) IL135581A0 (de)
NO (1) NO20001847L (de)
NZ (1) NZ503551A (de)
PL (1) PL341062A1 (de)
TR (1) TR200001040T2 (de)
WO (1) WO1999020280A1 (de)
ZA (1) ZA989450B (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60113731T2 (de) 2001-01-31 2006-06-29 Pfizer Products Inc., Groton Als inhibitoren von pde4-isozymen geeignete etherderivate
US7250518B2 (en) 2001-01-31 2007-07-31 Pfizer Inc. Nicotinamide acids, amides, and their mimetics active as inhibitors of PDE4 isozymes
KR20030072614A (ko) 2001-01-31 2003-09-15 화이자 프로덕츠 인크. Ｐｄｅ４ 이소자임 억제제로 유용한 티아졸릴-,옥사졸릴-, 피롤릴- 및 이미다졸릴-산 아미드 유도체
CA2436535A1 (en) 2001-01-31 2002-08-08 Prizer Products Inc. Nicotinamide biaryl derivatives useful as inhibitors of pde4 isozymes
US20030175314A1 (en) * 2001-11-19 2003-09-18 Didriksen Erik Johannes Pharmaceutical composition for dermal application
US20060258703A1 (en) * 2003-07-17 2006-11-16 Ono Pharmaceutical Co., Ltd. Remedy for pruritus comprising piperidine derivative as the active ingredient
WO2005053672A1 (ja) * 2003-12-04 2005-06-16 Santen Pharmaceutical Co., Ltd. シロミラストまたはその塩を有効成分とする掻痒治療剤
JP2005187458A (ja) * 2003-12-04 2005-07-14 Santen Pharmaceut Co Ltd シロミラストまたはその塩を有効成分とする掻痒治療剤
JP5001012B2 (ja) 2004-02-14 2012-08-15 グラクソスミスクライン・リミテッド・ライアビリティ・カンパニー Ｈｍ７４ａ受容体活性を有する薬剤
JP2008137892A (ja) * 2005-03-04 2008-06-19 Eisai Co Ltd 止痒剤
EP2272848B1 (de) 2005-08-10 2012-12-26 Glaxosmithkline LLC Xanthinderivate als selektive HM74A-Agonisten
TWI404709B (zh) * 2006-02-21 2013-08-11 Eisai R&D Man Co Ltd 4- (3-benzamidophenyl) -6,7-dimethoxy-2-methylamine quinazoline derivatives
AU2007218725B2 (en) * 2006-02-21 2011-12-01 Eisai R & D Management Co., Ltd. 4-(3-benzoylaminophenyl)-6,7-dimethoxy-2- methylaminoquinazoline derivative
CA2678477A1 (en) 2007-02-16 2008-08-21 Eisai R&D Management Co., Ltd. Crystal, amorphous form and salt of methyl n-[3-(6,7-dimethoxy-2-methylaminoquinazolin-4-yl)phenyl]terephthalamic acid
EP2202229B1 (de) 2007-08-17 2012-03-14 Eisai R&D Management Co., Ltd. Neue zubereitung für die äusserliche anwendung
ATE538102T1 (de) 2007-08-17 2012-01-15 Eisai R&D Man Co Ltd Verfahren zur herstellung eines chinazolinderivats
ES2659458T3 (es) 2011-06-28 2018-03-15 Mitsubishi Tanabe Pharma Corporation Compuestos de naftaleno para tratar el prurito
WO2016119570A1 (zh) 2015-01-30 2016-08-04 上海珊顿医药科技有限公司 尿酸性或痛风性疾病的预防或治疗

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997035854A1 (de) * 1996-03-26 1997-10-02 Byk Gulden Lomberg Chemische Fabrik Gmbh Neue in 6-position substituierte phenanthridine
WO1997043288A1 (en) * 1996-05-15 1997-11-20 Byk Gulden Lomberg Chemische Fabrik Gmbh Novel imidazopyridines
WO1998040382A1 (en) * 1997-03-07 1998-09-17 Byk Gulden Lomberg Chemische Fabrik Gmbh Novel tetrazoles
WO1998041232A2 (en) * 1997-03-18 1998-09-24 Basf Aktiengesellschaft Compositions for modulating responsiveness to corticosteroids
WO1998055481A1 (en) * 1997-06-03 1998-12-10 Byk Gulden Lomberg Chemische Fabrik Gmbh Benzonaphthyridine

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2098846A1 (en) * 1990-12-21 1992-06-22 David G. Smith Xanthine derivatives

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997035854A1 (de) * 1996-03-26 1997-10-02 Byk Gulden Lomberg Chemische Fabrik Gmbh Neue in 6-position substituierte phenanthridine
WO1997043288A1 (en) * 1996-05-15 1997-11-20 Byk Gulden Lomberg Chemische Fabrik Gmbh Novel imidazopyridines
WO1998040382A1 (en) * 1997-03-07 1998-09-17 Byk Gulden Lomberg Chemische Fabrik Gmbh Novel tetrazoles
WO1998041232A2 (en) * 1997-03-18 1998-09-24 Basf Aktiengesellschaft Compositions for modulating responsiveness to corticosteroids
WO1998055481A1 (en) * 1997-06-03 1998-12-10 Byk Gulden Lomberg Chemische Fabrik Gmbh Benzonaphthyridine

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
DATABASE CA [online] CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; COHAN, V. L. ET AL: "In vitro pharmacology of the novel phosphodiesterase type 4 inhibitor, CP - 80633", XP002210532, retrieved from STN Database accession no. 125:237990 CA *
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (1996), 278(3), 1356-1361, 1996 *
See also references of WO9920280A1 *

Also Published As

Publication number Publication date
HUP0003792A2 (hu) 2001-10-28
NO20001847D0 (no) 2000-04-10
IL135581A0 (en) 2001-05-20
JP2001520196A (ja) 2001-10-30
NO20001847L (no) 2000-04-10
EP1030666A1 (de) 2000-08-30
NZ503551A (en) 2002-05-31
ZA989450B (en) 1999-04-19
PL341062A1 (en) 2001-03-26
KR20010031149A (ko) 2001-04-16
AU1093899A (en) 1999-05-10
CO4810374A1 (es) 1999-06-30
AR015966A1 (es) 2001-05-30
TR200001040T2 (tr) 2001-01-22
BR9814080A (pt) 2000-09-26
WO1999020280A1 (en) 1999-04-29
CA2306985A1 (en) 1999-04-29
HUP0003792A3 (en) 2001-12-28
CN1306426A (zh) 2001-08-01
CZ20001376A3 (cs) 2002-06-12
AU740875B2 (en) 2001-11-15

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