ZA987804B - A combination of a monoamine oxidase inhibitor and a H5-HT1b antagonists or agonist - Google Patents

A combination of a monoamine oxidase inhibitor and a H5-HT1b antagonists or agonist

Info

Publication number
ZA987804B
ZA987804B ZA987804A ZA987804A ZA987804B ZA 987804 B ZA987804 B ZA 987804B ZA 987804 A ZA987804 A ZA 987804A ZA 987804 A ZA987804 A ZA 987804A ZA 987804 B ZA987804 B ZA 987804B
Authority
ZA
South Africa
Prior art keywords
agonist
combination
monoamine oxidase
oxidase inhibitor
ht1b antagonists
Prior art date
Application number
ZA987804A
Other languages
English (en)
Inventor
Stefan Berg
Svante Ross
Seth-Olov Thorberg
Original Assignee
Astra Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Ab filed Critical Astra Ab
Publication of ZA987804B publication Critical patent/ZA987804B/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Neurology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
ZA987804A 1997-09-18 1998-08-27 A combination of a monoamine oxidase inhibitor and a H5-HT1b antagonists or agonist ZA987804B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9703376A SE9703376D0 (sv) 1997-09-18 1997-09-18 A new combination

Publications (1)

Publication Number Publication Date
ZA987804B true ZA987804B (en) 1999-03-18

Family

ID=20408296

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA987804A ZA987804B (en) 1997-09-18 1998-08-27 A combination of a monoamine oxidase inhibitor and a H5-HT1b antagonists or agonist

Country Status (27)

Country Link
US (1) US6159970A (fr)
EP (1) EP1014986B1 (fr)
JP (1) JP2001516719A (fr)
KR (2) KR20010024087A (fr)
CN (1) CN1278727A (fr)
AR (1) AR013503A1 (fr)
AT (1) ATE270889T1 (fr)
AU (1) AU752719B2 (fr)
BR (1) BR9812236A (fr)
CA (1) CA2302204A1 (fr)
DE (1) DE69825062T2 (fr)
DK (1) DK1014986T3 (fr)
EE (1) EE200000146A (fr)
ES (1) ES2222603T3 (fr)
HU (1) HUP0100621A2 (fr)
ID (1) ID25789A (fr)
IL (1) IL134775A0 (fr)
IS (1) IS5401A (fr)
MX (1) MXPA00002616A (fr)
NO (1) NO20001400L (fr)
PL (1) PL339368A1 (fr)
PT (1) PT1014986E (fr)
SE (1) SE9703376D0 (fr)
SK (1) SK2832000A3 (fr)
TR (1) TR200000725T2 (fr)
WO (1) WO1999013878A1 (fr)
ZA (1) ZA987804B (fr)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4957948A (en) * 1988-05-05 1990-09-18 Interface, Inc. Biocidal protective coating for heat exchanger coils
SE9601110D0 (sv) * 1996-03-22 1996-03-22 Astra Ab Substituted 1,2,3,4-tetrahydronaphthalene derivatives
WO2002066454A1 (fr) * 2001-02-21 2002-08-29 Sankyo Company, Limited Derives de chromene
EP1408976B3 (fr) * 2001-07-20 2010-08-25 Psychogenics Inc. Traitement des troubles de deficit de l'attention/hyperactivite
US7732162B2 (en) 2003-05-05 2010-06-08 Probiodrug Ag Inhibitors of glutaminyl cyclase for treating neurodegenerative diseases
US20090054453A1 (en) * 2006-03-17 2009-02-26 Lilian Alcaraz Novel Tetralins as 5-HT6 Modulators
EP2089383B1 (fr) 2006-11-09 2015-09-16 Probiodrug AG Dérivés 3-hydr0xy-1,5-dihydr0-pyrr0l-2-one utiles en tant qu' inhibiteurs de la glutaminyl-cyclase dans le traitement des ulcères, du cancer et d'autres maladies
ATE554085T1 (de) 2006-11-30 2012-05-15 Probiodrug Ag Neue inhibitoren von glutaminylcyclase
MX2009009234A (es) 2007-03-01 2009-12-01 Probiodrug Ag Uso nuevo de inhibidores de ciclasa de glutaminilo.
WO2008128985A1 (fr) 2007-04-18 2008-10-30 Probiodrug Ag Dérivés de thio-urée utilisés comme inhibiteurs de la glutaminyl cyclase
KR101755737B1 (ko) 2009-09-11 2017-07-07 프로비오드룩 아게 글루타미닐 사이클라제의 억제제로서 헤테로사이클릭 유도체
US9181233B2 (en) 2010-03-03 2015-11-10 Probiodrug Ag Inhibitors of glutaminyl cyclase
CA2789440C (fr) 2010-03-10 2020-03-24 Probiodrug Ag Inhibiteurs heterocycliques de la glutaminyl cyclase (qc, ec 2.3.2.5)
JP5945532B2 (ja) 2010-04-21 2016-07-05 プロビオドルグ エージー グルタミニルシクラーゼの阻害剤としてのベンゾイミダゾール誘導体
ES2570167T3 (es) 2011-03-16 2016-05-17 Probiodrug Ag Derivados de benzimidazol como inhibidores de glutaminil ciclasa
ES2812698T3 (es) 2017-09-29 2021-03-18 Probiodrug Ag Inhibidores de glutaminil ciclasa
WO2020183011A1 (fr) 2019-03-14 2020-09-17 Institut Curie Inhibiteurs de htr1d et leurs utilisations dans le traitement du cancer
CN110179988A (zh) * 2019-07-10 2019-08-30 王大伟 五羟色胺再摄取抑制剂和单胺氧化酶抑制剂联合在制备治疗抑郁症或早泄药物中的应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0533268B1 (fr) * 1991-09-18 2001-08-16 Glaxo Group Limited Dérivés de benzanilide comme 5-HT1D antagonistes
GB9119932D0 (en) * 1991-09-18 1991-10-30 Glaxo Group Ltd Chemical compounds
SE9601110D0 (sv) * 1996-03-22 1996-03-22 Astra Ab Substituted 1,2,3,4-tetrahydronaphthalene derivatives

Also Published As

Publication number Publication date
SE9703376D0 (sv) 1997-09-18
TR200000725T2 (tr) 2000-08-21
KR20010024087A (ko) 2001-03-26
ATE270889T1 (de) 2004-07-15
AU9193198A (en) 1999-04-05
WO1999013878A1 (fr) 1999-03-25
DE69825062T2 (de) 2005-08-25
CA2302204A1 (fr) 1999-03-25
IL134775A0 (en) 2001-04-30
AR013503A1 (es) 2000-12-27
NO20001400L (no) 2000-05-05
SK2832000A3 (en) 2000-09-12
IS5401A (is) 2000-03-14
EE200000146A (et) 2001-02-15
ID25789A (id) 2000-11-02
DE69825062D1 (de) 2004-08-19
ES2222603T3 (es) 2005-02-01
PT1014986E (pt) 2004-10-29
EP1014986A1 (fr) 2000-07-05
DK1014986T3 (da) 2004-10-25
BR9812236A (pt) 2000-07-18
KR20010024084A (ko) 2001-03-26
EP1014986B1 (fr) 2004-07-14
CN1278727A (zh) 2001-01-03
MXPA00002616A (es) 2002-04-24
NO20001400D0 (no) 2000-03-17
PL339368A1 (en) 2000-12-18
US6159970A (en) 2000-12-12
HUP0100621A2 (hu) 2001-08-28
AU752719B2 (en) 2002-09-26
JP2001516719A (ja) 2001-10-02

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