ZA982225B - LHRH antagonists. - Google Patents

LHRH antagonists.

Info

Publication number
ZA982225B
ZA982225B ZA9802225A ZA982225A ZA982225B ZA 982225 B ZA982225 B ZA 982225B ZA 9802225 A ZA9802225 A ZA 9802225A ZA 982225 A ZA982225 A ZA 982225A ZA 982225 B ZA982225 B ZA 982225B
Authority
ZA
South Africa
Prior art keywords
lhrh antagonists
lhrh
antagonists
Prior art date
Application number
ZA9802225A
Other languages
English (en)
Inventor
Juergen Prof Dr Engel
Wolfgang Dr Deger
Thomas Dr Reissmann
Guenter Prof Losse
Wolfgang Dr Naumann
Sandra Murgas
Original Assignee
Asta Medica Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Asta Medica Ag filed Critical Asta Medica Ag
Publication of ZA982225B publication Critical patent/ZA982225B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A61K38/09—Luteinising hormone-releasing hormone [LHRH], i.e. Gonadotropin-releasing hormone [GnRH]; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
    • A61K47/645—Polycationic or polyanionic oligopeptides, polypeptides or polyamino acids, e.g. polylysine, polyarginine, polyglutamic acid or peptide TAT
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Reproductive Health (AREA)
  • Epidemiology (AREA)
  • Endocrinology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ZA9802225A 1997-03-26 1998-03-17 LHRH antagonists. ZA982225B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19712718A DE19712718C2 (de) 1997-03-26 1997-03-26 Immobilisierte und aktivitätsstabilisierte Komplexe von LHRH-Antagonisten und Verfahren zu deren Herstellung

Publications (1)

Publication Number Publication Date
ZA982225B true ZA982225B (en) 1998-04-03

Family

ID=7824698

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA9802225A ZA982225B (en) 1997-03-26 1998-03-17 LHRH antagonists.

Country Status (27)

Country Link
US (2) US6022860A (ru)
EP (1) EP0981377B1 (ru)
JP (1) JP4180120B2 (ru)
CN (1) CN1150943C (ru)
AR (1) AR012186A1 (ru)
AT (1) ATE249245T1 (ru)
AU (1) AU747808B2 (ru)
BR (1) BR9807887B1 (ru)
CA (1) CA2285054C (ru)
CZ (1) CZ300755B6 (ru)
DE (2) DE19712718C2 (ru)
DK (1) DK0981377T3 (ru)
ES (1) ES2206912T3 (ru)
HK (1) HK1025255A1 (ru)
HU (1) HUP0002059A3 (ru)
IL (1) IL131181A (ru)
NO (1) NO327404B1 (ru)
NZ (1) NZ337343A (ru)
PL (1) PL190090B1 (ru)
PT (1) PT981377E (ru)
RU (1) RU2207151C2 (ru)
SK (1) SK284461B6 (ru)
TR (1) TR199902168T2 (ru)
TW (1) TW520288B (ru)
UA (1) UA69381C2 (ru)
WO (1) WO1998042381A1 (ru)
ZA (1) ZA982225B (ru)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6828415B2 (en) * 1993-02-19 2004-12-07 Zentaris Gmbh Oligopeptide lyophilisate, their preparation and use
EP0788799A3 (en) * 1996-02-07 1998-10-21 ASTA Medica Aktiengesellschaft LHRH-Antagonists in the treatment of fertility disorders
US5968895A (en) 1996-12-11 1999-10-19 Praecis Pharmaceuticals, Inc. Pharmaceutical formulations for sustained drug delivery
US20070185032A1 (en) * 1996-12-11 2007-08-09 Praecis Pharmaceuticals, Inc. Pharmaceutical formulations for sustained drug delivery
WO1999055357A1 (en) * 1998-04-23 1999-11-04 Asta Medica Aktiengesellschaft Method for the treatment of fertility disorders
CO5160256A1 (es) * 1999-02-08 2002-05-30 Zentaris Ag Sales de peptidos farmaceuticamente activos para la liberacion sostenida y proceso de produccion
DE10024451A1 (de) * 2000-05-18 2001-11-29 Asta Medica Ag Pharmazeutische Darreichungsform für Peptide, Verfahren zu deren Herstellung und Verwendung
ATE552859T1 (de) * 2000-09-13 2012-04-15 Praecis Pharm Inc Pharmazeutische formulierungen zur kontinuierlichen abgabe von peptiden
US20020169125A1 (en) * 2001-03-21 2002-11-14 Cell Therapeutics, Inc. Recombinant production of polyanionic polymers and uses thereof
WO2003005889A2 (en) * 2001-07-10 2003-01-23 Ams Research Corporation Surgical kit for treating prostate tissue
US7214662B2 (en) 2001-11-27 2007-05-08 Zentaris Gmbh Injectable solution of an LHRH antagonist
US8093207B2 (en) * 2005-12-09 2012-01-10 Unigene Laboratories, Inc. Fast-acting oral peptide pharmaceutical products
US9232959B2 (en) 2007-01-02 2016-01-12 Aquabeam, Llc Multi fluid tissue resection methods and devices
EP2810613B1 (en) 2007-01-02 2019-03-20 AquaBeam LLC Minimally invasive devices for the treatment of prostate diseases
US8814921B2 (en) * 2008-03-06 2014-08-26 Aquabeam Llc Tissue ablation and cautery with optical energy carried in fluid stream
US9848904B2 (en) 2009-03-06 2017-12-26 Procept Biorobotics Corporation Tissue resection and treatment with shedding pulses
WO2016037137A1 (en) 2014-09-05 2016-03-10 Procept Biorobotics Corporation Physician controlled tissue resection integrated with treatment mapping of target organ images
US8853354B2 (en) 2009-03-27 2014-10-07 Kagoshima University Polyion complex comprising hydrophobized polyamino acid and use of the same
JP6080872B2 (ja) 2012-02-29 2017-02-15 プロセプト バイオロボティクス コーポレイション 自動化された画像誘導組織切除および治療
CN105431096B (zh) 2013-02-14 2018-07-31 普罗赛普特生物机器人公司 液体消融液体束眼外科手术的方法和装置
CN109965976B (zh) 2013-09-06 2022-05-31 普罗赛普特生物机器人公司 利用致脱脉冲的用于消融组织的装置
EP4070744A1 (en) 2014-06-30 2022-10-12 PROCEPT BioRobotics Corporation Fluid jet tissue resection and cold coagulation (aquablation) apparatus

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE257197C (ru) *
US4341767A (en) * 1980-10-06 1982-07-27 Syntex Inc. Nonapeptide and decapeptide analogs of LHRH, useful as LHRH antagonists
DD257197A1 (de) * 1987-01-28 1988-06-08 Univ Dresden Tech Verfahren zur herstellung von immobilisierten, in ihrer biologischen aktivitaet stabilisierten und in ihren pharmakologischen eigenschaften modifizierten insulinpraeparationen
US4801577A (en) * 1987-02-05 1989-01-31 Syntex (U.S.A.) Inc. Nonapeptide and decapeptide analogs of LHRH useful as LHRH antagonists
DD269785A1 (de) * 1988-02-08 1989-07-12 Univ Dresden Tech Verfahren zur herstellung von aktivitaetsstabilisierten und in ihren pharmakologischen eigenschaften modifizierten peptidderivaten
DD273980B5 (de) * 1988-07-12 1994-04-14 Berlin Chemie Ag Verfahren zur Herstellung von Insulin-Pr{paraten zur rektalen Anwendung
DE59107006D1 (de) * 1990-04-25 1996-01-18 Hoechst Ag Pharmakologische Zubereitung, enthaltend Polyelektrolytkomplexe in mikropartikulärer Form und mindestens einen Wirkstoff.
DD299265A5 (de) * 1990-09-11 1992-04-09 Technische Universitaet Dresden,De Verfahren zur herstellung von immobilisierten und aktivitaetsstabilisierten praeparaten des gonadotropin-releasing-hormons oder dessen analoga mit polyaminosaeuren
US5834520A (en) * 1992-10-08 1998-11-10 Asta-Medica Aktiengesellschaft Container for injectable mesna solutions
EP0670728A4 (en) * 1992-11-12 1996-04-17 Molecular Dynamics Inc PIPTIDE-BASED LIPOPHILE-BASED CARRIERS FOR TARGETED MEDICINE ADMINISTRATION USING A RATIONAL MEDICINE-BINDING DESIGN.
DE4305225A1 (de) * 1993-02-19 1994-08-25 Asta Medica Ag Neues Herstellverfahren für Cetrorelix Lyophilisat
US5449720A (en) * 1993-05-24 1995-09-12 Biotech Australia Pty Limited Amplification of the VB12 uptake system using polymers
US5502035A (en) * 1993-08-06 1996-03-26 Tap Holdings Inc. N-terminus modified analogs of LHRH
CA2178592C (en) * 1993-12-09 2009-07-28 Jurgen Engel Long-acting injection suspensions and a process for their preparation
US5821230A (en) * 1997-04-11 1998-10-13 Ferring Bv GnRH antagonist decapeptides

Also Published As

Publication number Publication date
SK131699A3 (en) 2000-05-16
RU2207151C2 (ru) 2003-06-27
DE19712718A1 (de) 1998-10-01
DE19712718C2 (de) 1999-09-23
HUP0002059A2 (hu) 2000-10-28
CZ300755B6 (cs) 2009-08-05
JP2001520662A (ja) 2001-10-30
ATE249245T1 (de) 2003-09-15
US6054555A (en) 2000-04-25
IL131181A (en) 2004-09-27
AR012186A1 (es) 2000-09-27
PL190090B1 (pl) 2005-10-31
CA2285054A1 (en) 1998-10-01
NO994665L (no) 1999-09-24
TW520288B (en) 2003-02-11
NO994665D0 (no) 1999-09-24
US6022860A (en) 2000-02-08
UA69381C2 (ru) 2004-09-15
DE59809575D1 (de) 2003-10-16
WO1998042381A1 (de) 1998-10-01
EP0981377A1 (de) 2000-03-01
BR9807887A (pt) 2000-02-22
AU6920798A (en) 1998-10-20
EP0981377B1 (de) 2003-09-10
ES2206912T3 (es) 2004-05-16
CN1249691A (zh) 2000-04-05
AU747808B2 (en) 2002-05-23
DK0981377T3 (da) 2003-11-10
NZ337343A (en) 2001-10-26
HK1025255A1 (en) 2000-11-10
SK284461B6 (sk) 2005-04-01
JP4180120B2 (ja) 2008-11-12
BR9807887B1 (pt) 2010-05-18
PT981377E (pt) 2004-02-27
CN1150943C (zh) 2004-05-26
CA2285054C (en) 2007-08-21
IL131181A0 (en) 2001-01-28
HUP0002059A3 (en) 2001-02-28
CZ337199A3 (cs) 2000-03-15
NO327404B1 (no) 2009-06-22
PL335830A1 (en) 2000-05-22
TR199902168T2 (xx) 1999-12-21

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