ZA97288B - Angiogenesis inhibiting pyridazinamines - Google Patents

Angiogenesis inhibiting pyridazinamines

Info

Publication number
ZA97288B
ZA97288B ZA97288A ZA97288A ZA97288B ZA 97288 B ZA97288 B ZA 97288B ZA 97288 A ZA97288 A ZA 97288A ZA 97288 A ZA97288 A ZA 97288A ZA 97288 B ZA97288 B ZA 97288B
Authority
ZA
South Africa
Prior art keywords
6alkyl
alk
amino
6alkyloxy
hydrogen
Prior art date
Application number
ZA97288A
Other languages
English (en)
Inventor
Raymond Antoine Stokbroekx
Marcel Jozef Maria Van Der Aa
Marc Willems
Lieven Meerpoel
Marcel Gerebernus
Maria Luyckx
Robert W Tuman
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of ZA97288B publication Critical patent/ZA97288B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50—Pyridazines; Hydrogenated pyridazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Cardiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
ZA97288A 1996-01-15 1997-01-14 Angiogenesis inhibiting pyridazinamines ZA97288B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP96200085 1996-01-15

Publications (1)

Publication Number Publication Date
ZA97288B true ZA97288B (en) 1998-07-14

Family

ID=8223585

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA97288A ZA97288B (en) 1996-01-15 1997-01-14 Angiogenesis inhibiting pyridazinamines

Country Status (21)

Country Link
US (1) US5985878A (ko)
EP (1) EP0876366B1 (ko)
JP (1) JP4169368B2 (ko)
KR (1) KR100443893B1 (ko)
CN (1) CN1104430C (ko)
AT (1) ATE203534T1 (ko)
AU (1) AU717744B2 (ko)
CA (1) CA2237273C (ko)
DE (1) DE69705819T2 (ko)
DK (1) DK0876366T3 (ko)
ES (1) ES2162235T3 (ko)
GR (1) GR3036900T3 (ko)
IL (1) IL124461A (ko)
MY (1) MY117098A (ko)
NO (1) NO309653B1 (ko)
NZ (1) NZ326354A (ko)
PT (1) PT876366E (ko)
SI (1) SI0876366T1 (ko)
TW (1) TW480256B (ko)
WO (1) WO1997026258A1 (ko)
ZA (1) ZA97288B (ko)

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EP1804799B1 (en) 2004-09-20 2013-08-21 Xenon Pharmaceuticals Inc. Heterocyclic derivatives and their use as stearoyl-coa desaturase inhibitors
JP5149009B2 (ja) 2004-09-20 2013-02-20 ゼノン・ファーマシューティカルズ・インコーポレイテッド ヒトステアロイル−ＣｏＡデサチュラーゼを阻害するためのピリダジン誘導体
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US11046658B2 (en) 2018-07-02 2021-06-29 Incyte Corporation Aminopyrazine derivatives as PI3K-γ inhibitors
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Also Published As

Publication number Publication date
US5985878A (en) 1999-11-16
KR100443893B1 (ko) 2004-10-15
EP0876366A2 (en) 1998-11-11
PT876366E (pt) 2002-01-30
CN1208415A (zh) 1999-02-17
NZ326354A (en) 1999-05-28
GR3036900T3 (en) 2002-01-31
CN1104430C (zh) 2003-04-02
DE69705819T2 (de) 2002-04-11
CA2237273A1 (en) 1997-07-24
WO1997026258A1 (en) 1997-07-24
NO309653B1 (no) 2001-03-05
AU717744B2 (en) 2000-03-30
DK0876366T3 (da) 2001-11-05
IL124461A0 (en) 1998-12-06
MY117098A (en) 2004-05-31
KR19990067654A (ko) 1999-08-25
JP2000503014A (ja) 2000-03-14
DE69705819D1 (de) 2001-08-30
NO982037L (no) 1998-09-15
TW480256B (en) 2002-03-21
ES2162235T3 (es) 2001-12-16
ATE203534T1 (de) 2001-08-15
CA2237273C (en) 2009-01-13
EP0876366B1 (en) 2001-07-25
JP4169368B2 (ja) 2008-10-22
SI0876366T1 (en) 2001-12-31
NO982037D0 (no) 1998-05-05
IL124461A (en) 2000-07-26
AU1443997A (en) 1997-08-11

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