DK0876366T3 - Angiogenese-inhiberende pyridazinaminer - Google Patents

Angiogenese-inhiberende pyridazinaminer

Info

Publication number
DK0876366T3
DK0876366T3 DK97901059T DK97901059T DK0876366T3 DK 0876366 T3 DK0876366 T3 DK 0876366T3 DK 97901059 T DK97901059 T DK 97901059T DK 97901059 T DK97901059 T DK 97901059T DK 0876366 T3 DK0876366 T3 DK 0876366T3
Authority
DK
Denmark
Prior art keywords
6alkyl
alk
amino
6alkyloxy
hydrogen
Prior art date
Application number
DK97901059T
Other languages
English (en)
Inventor
Raymond Antoine Jan Stokbroekx
Der Aa Marcel Jozef Maria Van
Marc Willems
Lieven Meerpoel
Marcel Gerebernus Maria Luyckx
Robert W Tuman
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Application granted granted Critical
Publication of DK0876366T3 publication Critical patent/DK0876366T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50—Pyridazines; Hydrogenated pyridazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Cardiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
DK97901059T 1996-01-15 1997-01-14 Angiogenese-inhiberende pyridazinaminer DK0876366T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP96200085 1996-01-15
PCT/EP1997/000201 WO1997026258A1 (en) 1996-01-15 1997-01-14 Angiogenesis inhibiting pyridazinamines

Publications (1)

Publication Number Publication Date
DK0876366T3 true DK0876366T3 (da) 2001-11-05

Family

ID=8223585

Family Applications (1)

Application Number Title Priority Date Filing Date
DK97901059T DK0876366T3 (da) 1996-01-15 1997-01-14 Angiogenese-inhiberende pyridazinaminer

Country Status (21)

Country Link
US (1) US5985878A (da)
EP (1) EP0876366B1 (da)
JP (1) JP4169368B2 (da)
KR (1) KR100443893B1 (da)
CN (1) CN1104430C (da)
AT (1) ATE203534T1 (da)
AU (1) AU717744B2 (da)
CA (1) CA2237273C (da)
DE (1) DE69705819T2 (da)
DK (1) DK0876366T3 (da)
ES (1) ES2162235T3 (da)
GR (1) GR3036900T3 (da)
IL (1) IL124461A (da)
MY (1) MY117098A (da)
NO (1) NO309653B1 (da)
NZ (1) NZ326354A (da)
PT (1) PT876366E (da)
SI (1) SI0876366T1 (da)
TW (1) TW480256B (da)
WO (1) WO1997026258A1 (da)
ZA (1) ZA97288B (da)

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DE102004003812A1 (de) * 2004-01-25 2005-08-11 Aventis Pharma Deutschland Gmbh Arylsubstituierte Heterozyklen, Verfahren ihrer Herstellung und ihre Verwendung als Arzneimittel
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CN101084207A (zh) 2004-09-20 2007-12-05 泽农医药公司 杂环衍生物及其作为硬脂酰CoA去饱和酶抑制剂的用途
CN101083982A (zh) 2004-09-20 2007-12-05 泽农医药公司 用于治疗硬脂酰CoA去饱和酶介导的疾病的杂环衍生物
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AU2005329423A1 (en) * 2004-09-20 2006-09-28 Xenon Pharmaceuticals Inc. Heterocyclic derivatives and their use as stearoyl-CoA desaturase inhibitors
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CN102216292B (zh) 2008-11-17 2014-08-13 伊莱利利公司 四取代的哒嗪hedgehog途径拮抗剂
AR077014A1 (es) 2009-06-19 2011-07-27 Lilly Co Eli Compuesto derivado de ftalazina 1,4-disustituida, composicion farmaceutica que lo comprende y uso para preparar un medicamento util para el tratamiento de cancer
WO2011002067A1 (ja) * 2009-07-02 2011-01-06 武田薬品工業株式会社 複素環化合物およびその用途
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US9238658B2 (en) 2011-12-06 2016-01-19 Janssen Pharmaceutica Nv Substituted piperidinyl-carboxamide derivatives useful as SCD 1 inhibitors
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SI3762368T1 (sl) 2018-03-08 2022-06-30 Incyte Corporation Aminopirazin diolne spojine kot zaviralci PI3K-y
US11046658B2 (en) 2018-07-02 2021-06-29 Incyte Corporation Aminopyrazine derivatives as PI3K-γ inhibitors
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Also Published As

Publication number Publication date
EP0876366B1 (en) 2001-07-25
IL124461A (en) 2000-07-26
JP2000503014A (ja) 2000-03-14
ATE203534T1 (de) 2001-08-15
NO982037D0 (no) 1998-05-05
TW480256B (en) 2002-03-21
KR100443893B1 (ko) 2004-10-15
SI0876366T1 (en) 2001-12-31
JP4169368B2 (ja) 2008-10-22
CN1104430C (zh) 2003-04-02
MY117098A (en) 2004-05-31
CA2237273C (en) 2009-01-13
KR19990067654A (ko) 1999-08-25
PT876366E (pt) 2002-01-30
GR3036900T3 (en) 2002-01-31
NZ326354A (en) 1999-05-28
EP0876366A2 (en) 1998-11-11
AU1443997A (en) 1997-08-11
ZA97288B (en) 1998-07-14
AU717744B2 (en) 2000-03-30
WO1997026258A1 (en) 1997-07-24
IL124461A0 (en) 1998-12-06
NO309653B1 (no) 2001-03-05
CN1208415A (zh) 1999-02-17
NO982037L (no) 1998-09-15
CA2237273A1 (en) 1997-07-24
ES2162235T3 (es) 2001-12-16
DE69705819D1 (de) 2001-08-30
DE69705819T2 (de) 2002-04-11
US5985878A (en) 1999-11-16

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