ZA967800B - Heteroaryllsubstituted acryloylguanidine derivatives and pharmaceutical compositions comprising them - Google Patents
Heteroaryllsubstituted acryloylguanidine derivatives and pharmaceutical compositions comprising themInfo
- Publication number
- ZA967800B ZA967800B ZA967800A ZA967800A ZA967800B ZA 967800 B ZA967800 B ZA 967800B ZA 967800 A ZA967800 A ZA 967800A ZA 967800 A ZA967800 A ZA 967800A ZA 967800 B ZA967800 B ZA 967800B
- Authority
- ZA
- South Africa
- Prior art keywords
- heteroaryllsubstituted
- pharmaceutical compositions
- acryloylguanidine
- derivatives
- acryloylguanidine derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
- C07D213/82—Amides; Imides in position 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D207/325—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
- C07D207/327—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/357—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
- A61K31/36—Compounds containing methylenedioxyphenyl groups, e.g. sesamin
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP24171695 | 1995-09-20 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA967800B true ZA967800B (en) | 1997-04-03 |
Family
ID=17078479
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA967800A ZA967800B (en) | 1995-09-20 | 1996-09-16 | Heteroaryllsubstituted acryloylguanidine derivatives and pharmaceutical compositions comprising them |
Country Status (13)
| Country | Link |
|---|---|
| EP (1) | EP0861831A4 (fr) |
| KR (1) | KR19990063589A (fr) |
| CN (1) | CN1196721A (fr) |
| AU (1) | AU702092B2 (fr) |
| BR (1) | BR9610530A (fr) |
| CA (1) | CA2232497A1 (fr) |
| CZ (1) | CZ84098A3 (fr) |
| HU (1) | HUP9901336A3 (fr) |
| NO (1) | NO981241L (fr) |
| PL (1) | PL326033A1 (fr) |
| SK (1) | SK35198A3 (fr) |
| WO (1) | WO1997011055A1 (fr) |
| ZA (1) | ZA967800B (fr) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE69616364T2 (de) * | 1995-08-02 | 2002-07-11 | Smithkline Beecham Corp | Endothelinrezeptorantagonisten |
| JP3652708B2 (ja) * | 1997-03-06 | 2005-05-25 | トーアエイヨー株式会社 | シクロアルカ［ｂ］ピリジン−３−カルボニルグアニジン誘導体、その製造法およびそれを含有する医薬品 |
| WO2001014363A1 (fr) * | 1999-08-23 | 2001-03-01 | Smithkline Beecham Corporation | Inhibiteurs de synthase d'acide gras |
| DE60123665T2 (de) * | 2000-12-26 | 2007-08-16 | Sankyo Co., Ltd. | Medizinische zusammensetzungen mit diuretischem und die insulinresistenz verbesserndem mittel |
| EP1758907B1 (fr) | 2004-06-16 | 2009-02-18 | Wyeth | Diphenylimidazopyrimidine et -imidazole amines utilisees comme inhibiteurs de b-secretase |
| BRPI0512213A (pt) | 2004-06-16 | 2008-02-19 | Wyeth Corp | método para tratamento, prevenção ou melhora de uma doença ou distúrbio; composição farmacêutica; processo para a preparação de um composto; e uso de um composto |
| JP2008526966A (ja) | 2005-01-14 | 2008-07-24 | ワイス | β−セクレターゼの阻害のためのアミノ−イミダゾロン |
| AU2006211159A1 (en) | 2005-02-01 | 2006-08-10 | Wyeth | Amino-pyridines as inhibitors of beta-secretase |
| RU2007131043A (ru) | 2005-02-14 | 2009-03-20 | Вайет (Us) | Азолилацилгуанидины, применяемые в качестве ингибиторов бета-секретазы |
| WO2006088694A1 (fr) | 2005-02-14 | 2006-08-24 | Wyeth | THIÉNYL- ET FURYLACYLGUANIDINE SUBSTITUÉES ET MÉTHODES D'EMPLOI DESDITS COMPOSÉS EN TANT QUE RÉGULATEURS DE LA β-SECRÉTASE |
| AU2006266167A1 (en) | 2005-06-30 | 2007-01-11 | Wyeth | Amino-5-(6-membered)heteroarylimidazolone compounds and the use thereof for beta-secretase modulation |
| TW200738683A (en) | 2005-06-30 | 2007-10-16 | Wyeth Corp | Amino-5-(5-membered)heteroarylimidazolone compounds and the use thereof for β-secretase modulation |
| AU2006294620A1 (en) | 2005-09-26 | 2007-04-05 | Wyeth | Amino-5- [4- (difluoromethoxy) phenyl] -5-phenylimidazolone compounds as inhibitors of the beta-secretase (bace) |
| WO2007100536A1 (fr) | 2006-02-24 | 2007-09-07 | Wyeth | COMPOSES DE DIHYDROSPIRO[DIBENZO[A,D][7]ANNULENE-5,4'-IMIDAZOL] POUR L'INHIBITION DE LA β-SECRETASE |
| US7700606B2 (en) | 2006-08-17 | 2010-04-20 | Wyeth Llc | Imidazole amines as inhibitors of β-secretase |
| AR065814A1 (es) | 2007-03-23 | 2009-07-01 | Wyeth Corp | Derivados de 5-fenilimidazolona,inhibidores de beta-secretasa,composiciones farmaceuticas que los contienen y usos para prevenir y/o tratar trastornos asociados a niveles beta-amiloides elevados. |
| WO2018065288A1 (fr) | 2016-10-07 | 2018-04-12 | Bayer Cropscience Aktiengesellschaft | Dérivés de 2-[2-phényl-1-(sulfonylméthyl)vinyl]-imidazo[4,5-b]pyridine et composés apparentés utilisés comme pesticides en protection des plantes |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3929582A1 (de) | 1989-09-06 | 1991-03-07 | Hoechst Ag | Benzoylguanidine, verfahren zu ihrer herstellung, ihre verwendung als medikament sowie sie enthaltendes medikament |
| ATE139526T1 (de) * | 1992-02-15 | 1996-07-15 | Hoechst Ag | 3,5-substituierte benzoylguanidine, mit antiarrythmischer wirkung und inhibierender wirkung auf die proliferationen von zellen |
| JP3162572B2 (ja) * | 1993-04-28 | 2001-05-08 | 住友製薬株式会社 | インドロイルグアニジン誘導体 |
| US5401758A (en) * | 1993-10-07 | 1995-03-28 | Bristol-Myers Squibb Company | Pyridinyl cyanoguanidine compounds |
| DE4430861A1 (de) * | 1994-08-31 | 1996-03-07 | Merck Patent Gmbh | Heterocyclyl-benzoylguanidine |
| JPH0959245A (ja) * | 1995-08-25 | 1997-03-04 | Yamanouchi Pharmaceut Co Ltd | Ｎ−（２−プロペノイル）グアニジン誘導体 |
-
1996
- 1996-09-16 ZA ZA967800A patent/ZA967800B/xx unknown
- 1996-09-19 CA CA002232497A patent/CA2232497A1/fr not_active Abandoned
- 1996-09-19 CZ CZ98840A patent/CZ84098A3/cs unknown
- 1996-09-19 AU AU70007/96A patent/AU702092B2/en not_active Ceased
- 1996-09-19 PL PL96326033A patent/PL326033A1/xx unknown
- 1996-09-19 HU HU9901336A patent/HUP9901336A3/hu unknown
- 1996-09-19 EP EP96931252A patent/EP0861831A4/fr not_active Withdrawn
- 1996-09-19 KR KR1019980702028A patent/KR19990063589A/ko not_active Application Discontinuation
- 1996-09-19 BR BR9610530A patent/BR9610530A/pt not_active Application Discontinuation
- 1996-09-19 WO PCT/JP1996/002696 patent/WO1997011055A1/fr not_active Application Discontinuation
- 1996-09-19 CN CN96196999A patent/CN1196721A/zh active Pending
- 1996-09-19 SK SK351-98A patent/SK35198A3/sk unknown
-
1998
- 1998-03-19 NO NO981241A patent/NO981241L/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CA2232497A1 (fr) | 1997-03-27 |
| PL326033A1 (en) | 1998-08-17 |
| MX9802238A (es) | 1998-08-30 |
| CZ84098A3 (cs) | 1998-09-16 |
| WO1997011055A1 (fr) | 1997-03-27 |
| KR19990063589A (ko) | 1999-07-26 |
| AU7000796A (en) | 1997-04-09 |
| HUP9901336A2 (hu) | 1999-08-30 |
| NO981241L (no) | 1998-05-20 |
| NO981241D0 (no) | 1998-03-19 |
| EP0861831A1 (fr) | 1998-09-02 |
| EP0861831A4 (fr) | 1998-11-11 |
| SK35198A3 (en) | 1999-06-11 |
| BR9610530A (pt) | 1999-07-06 |
| AU702092B2 (en) | 1999-02-11 |
| HUP9901336A3 (en) | 2000-02-28 |
| CN1196721A (zh) | 1998-10-21 |
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