ZA961314B - Substituted benzenesulfonylureas and -thioreas processes for their preparation their use for the production of pharmaceutical preparations and medicaments containing them - Google Patents

Substituted benzenesulfonylureas and -thioreas processes for their preparation their use for the production of pharmaceutical preparations and medicaments containing them

Info

Publication number
ZA961314B
ZA961314B ZA961314A ZA961314A ZA961314B ZA 961314 B ZA961314 B ZA 961314B ZA 961314 A ZA961314 A ZA 961314A ZA 961314 A ZA961314 A ZA 961314A ZA 961314 B ZA961314 B ZA 961314B
Authority
ZA
South Africa
Prior art keywords
thioreas
processes
preparation
production
pharmaceutical preparations
Prior art date
Application number
ZA961314A
Other languages
English (en)
Inventor
Heinrich Englert
Uwe Gerlach
Dieter Mania
Heinz Goegelein
Joachim Kaiser
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of ZA961314B publication Critical patent/ZA961314B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D303/00Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02Compounds containing oxirane rings
    • C07D303/48Compounds containing oxirane rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms, e.g. ester or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/50Compounds containing any of the groups, X being a hetero atom, Y being any atom
    • C07C311/52Y being a hetero atom
    • C07C311/54Y being a hetero atom either X or Y, but not both, being nitrogen atoms, e.g. N-sulfonylurea
    • C07C311/57Y being a hetero atom either X or Y, but not both, being nitrogen atoms, e.g. N-sulfonylurea having sulfur atoms of the sulfonylurea groups bound to carbon atoms of six-membered aromatic rings
    • C07C311/58Y being a hetero atom either X or Y, but not both, being nitrogen atoms, e.g. N-sulfonylurea having sulfur atoms of the sulfonylurea groups bound to carbon atoms of six-membered aromatic rings having nitrogen atoms of the sulfonylurea groups bound to hydrogen atoms or to acyclic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/02Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C335/00Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C335/40Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of thiourea or isothiourea groups further bound to other hetero atoms
    • C07C335/42Sulfonylthioureas; Sulfonylisothioureas
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/02Systems containing only non-condensed rings with a three-membered ring

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Hospice & Palliative Care (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Epoxy Compounds (AREA)
ZA961314A 1995-02-21 1994-02-20 Substituted benzenesulfonylureas and -thioreas processes for their preparation their use for the production of pharmaceutical preparations and medicaments containing them ZA961314B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19505910A DE19505910A1 (de) 1995-02-21 1995-02-21 Substituierte Benzolsulfonylharnstoffe und -thioharnstoffe, Verfahren zu ihrer Herstellung, ihre Verwendung zur Herstellung pharmazeutischer Präparate und sie enthaltende Medikamente

Publications (1)

Publication Number Publication Date
ZA961314B true ZA961314B (en) 1996-08-27

Family

ID=7754593

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA961314A ZA961314B (en) 1995-02-21 1994-02-20 Substituted benzenesulfonylureas and -thioreas processes for their preparation their use for the production of pharmaceutical preparations and medicaments containing them

Country Status (30)

Country Link
US (1) US5633239A (no)
EP (1) EP0728741B1 (no)
JP (1) JP3905570B2 (no)
KR (1) KR100446566B1 (no)
CN (1) CN1060767C (no)
AR (1) AR001352A1 (no)
AT (1) ATE196467T1 (no)
AU (1) AU701278B2 (no)
BR (1) BR9600773A (no)
CA (1) CA2169695C (no)
CZ (1) CZ291219B6 (no)
DE (2) DE19505910A1 (no)
DK (1) DK0728741T3 (no)
ES (1) ES2151614T3 (no)
FI (1) FI120392B (no)
GR (1) GR3034646T3 (no)
HR (1) HRP960081B1 (no)
HU (1) HU227308B1 (no)
IL (1) IL117179A (no)
MY (1) MY113432A (no)
NO (1) NO305792B1 (no)
NZ (1) NZ286013A (no)
PL (1) PL181628B1 (no)
PT (1) PT728741E (no)
RU (1) RU2159763C2 (no)
SI (1) SI9600053B (no)
SK (1) SK281876B6 (no)
TR (1) TR199600129A2 (no)
TW (1) TW357140B (no)
ZA (1) ZA961314B (no)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19832009A1 (de) 1998-07-16 2000-01-20 Hoechst Marion Roussel De Gmbh 2,5-Substituierte Benzolsulfonylharnstoffe und -thioharnstoffe, Verfahren zu ihrer Herstellung, ihre Verwendung und sie enthaltende pharamazeutische Präparate
US6436864B1 (en) 1999-10-06 2002-08-20 Sri International Unsaturated nitrogenous compounds as electron donors for use with ziegler-natta catalysts
DE10129704A1 (de) * 2001-06-22 2003-01-02 Aventis Pharma Gmbh Verwendung von Benzolsulfonyl(thio)harnstoffen in der Behandlung des septischen Schocks
CN101160285A (zh) * 2005-03-17 2008-04-09 辉瑞大药厂 适用于治疗疼痛的n-(n-磺酰氨基甲基)环丙烷甲酰胺衍生物

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL141381B (nl) * 1963-09-25 1974-03-15 Hoechst Ag Werkwijze voor het bereiden van geneesmiddelen met bloedsuikerspiegel verlagende werkzaamheid.
DE1198354B (de) * 1963-09-25 1965-08-12 Hoechst Ag Verfahren zur Herstellung von Benzol-sulfonylharnstoffen
BE754454A (fr) * 1969-08-06 1971-02-05 Bayer Ag Nouveaux composes hypoglycemiques du type d'arylsulfonylurees et d'arylsulfonylsemicarbazides contenant des groupes carbonamide
ES2098069T3 (es) * 1993-02-23 1997-04-16 Hoechst Ag Bencenosulfonil-ureas y -tioureas sustituidas, procedimiento para su preparacion y su utilizacion como agentes farmaceuticos.
DE4341655A1 (de) * 1993-12-07 1995-06-08 Hoechst Ag Aminosubstituierte Benzolsulfonylharnstoffe und -thioharnstoffe, Verfahren zu ihrer Herstellung und ihre Verwendung als Pharmazeutika

Also Published As

Publication number Publication date
CZ48696A3 (en) 1996-09-11
AU4560096A (en) 1996-08-29
MY113432A (en) 2002-02-28
KR960031429A (ko) 1996-09-17
PL181628B1 (pl) 2001-08-31
IL117179A (en) 2000-02-17
SK22296A3 (en) 1996-10-02
JPH08245555A (ja) 1996-09-24
NO305792B1 (no) 1999-07-26
NO960664L (no) 1996-08-22
BR9600773A (pt) 1997-12-23
SK281876B6 (sk) 2001-08-06
IL117179A0 (en) 1996-06-18
HU227308B1 (en) 2011-03-28
CN1060767C (zh) 2001-01-17
AU701278B2 (en) 1999-01-21
ATE196467T1 (de) 2000-10-15
HUT73974A (en) 1996-10-28
CN1134932A (zh) 1996-11-06
KR100446566B1 (ko) 2004-12-03
TW357140B (en) 1999-05-01
JP3905570B2 (ja) 2007-04-18
DE19505910A1 (de) 1996-08-22
ES2151614T3 (es) 2001-01-01
DK0728741T3 (da) 2000-12-18
EP0728741B1 (de) 2000-09-20
HU9503931D0 (en) 1996-03-28
TR199600129A2 (tr) 1996-10-21
HRP960081B1 (en) 2001-08-31
CA2169695A1 (en) 1996-08-22
SI9600053A (en) 1996-12-31
CA2169695C (en) 2008-05-20
RU2159763C2 (ru) 2000-11-27
PL312529A1 (en) 1996-09-02
DE59605898D1 (de) 2000-10-26
AR001352A1 (es) 1997-10-22
SI9600053B (en) 2001-12-31
HRP960081A2 (en) 1997-10-31
EP0728741A1 (de) 1996-08-28
FI120392B (fi) 2009-10-15
US5633239A (en) 1997-05-27
CZ291219B6 (cs) 2003-01-15
NZ286013A (en) 1996-10-28
GR3034646T3 (en) 2001-01-31
FI960740A (fi) 1996-08-22
NO960664D0 (no) 1996-02-20
FI960740A0 (fi) 1996-02-19
PT728741E (pt) 2001-03-30

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