IL117179A - Substituted benzenesulfonylureas and-thioureas processes for their preparation and use thereof in the production of medicaments and pharmaceutical compositions containing them - Google Patents
Substituted benzenesulfonylureas and-thioureas processes for their preparation and use thereof in the production of medicaments and pharmaceutical compositions containing themInfo
- Publication number
- IL117179A IL117179A IL11717996A IL11717996A IL117179A IL 117179 A IL117179 A IL 117179A IL 11717996 A IL11717996 A IL 11717996A IL 11717996 A IL11717996 A IL 11717996A IL 117179 A IL117179 A IL 117179A
- Authority
- IL
- Israel
- Prior art keywords
- thioureas
- medicaments
- processes
- preparation
- production
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/50—Compounds containing any of the groups, X being a hetero atom, Y being any atom
- C07C311/52—Y being a hetero atom
- C07C311/54—Y being a hetero atom either X or Y, but not both, being nitrogen atoms, e.g. N-sulfonylurea
- C07C311/57—Y being a hetero atom either X or Y, but not both, being nitrogen atoms, e.g. N-sulfonylurea having sulfur atoms of the sulfonylurea groups bound to carbon atoms of six-membered aromatic rings
- C07C311/58—Y being a hetero atom either X or Y, but not both, being nitrogen atoms, e.g. N-sulfonylurea having sulfur atoms of the sulfonylurea groups bound to carbon atoms of six-membered aromatic rings having nitrogen atoms of the sulfonylurea groups bound to hydrogen atoms or to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/48—Compounds containing oxirane rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms, e.g. ester or nitrile radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C335/00—Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C335/40—Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of thiourea or isothiourea groups further bound to other hetero atoms
- C07C335/42—Sulfonylthioureas; Sulfonylisothioureas
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/02—Systems containing only non-condensed rings with a three-membered ring
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Hospice & Palliative Care (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Epoxy Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19505910A DE19505910A1 (de) | 1995-02-21 | 1995-02-21 | Substituierte Benzolsulfonylharnstoffe und -thioharnstoffe, Verfahren zu ihrer Herstellung, ihre Verwendung zur Herstellung pharmazeutischer Präparate und sie enthaltende Medikamente |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL117179A0 IL117179A0 (en) | 1996-06-18 |
| IL117179A true IL117179A (en) | 2000-02-17 |
Family
ID=7754593
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL11717996A IL117179A (en) | 1995-02-21 | 1996-02-19 | Substituted benzenesulfonylureas and-thioureas processes for their preparation and use thereof in the production of medicaments and pharmaceutical compositions containing them |
Country Status (30)
| Country | Link |
|---|---|
| US (1) | US5633239A (no) |
| EP (1) | EP0728741B1 (no) |
| JP (1) | JP3905570B2 (no) |
| KR (1) | KR100446566B1 (no) |
| CN (1) | CN1060767C (no) |
| AR (1) | AR001352A1 (no) |
| AT (1) | ATE196467T1 (no) |
| AU (1) | AU701278B2 (no) |
| BR (1) | BR9600773A (no) |
| CA (1) | CA2169695C (no) |
| CZ (1) | CZ291219B6 (no) |
| DE (2) | DE19505910A1 (no) |
| DK (1) | DK0728741T3 (no) |
| ES (1) | ES2151614T3 (no) |
| FI (1) | FI120392B (no) |
| GR (1) | GR3034646T3 (no) |
| HR (1) | HRP960081B1 (no) |
| HU (1) | HU227308B1 (no) |
| IL (1) | IL117179A (no) |
| MY (1) | MY113432A (no) |
| NO (1) | NO305792B1 (no) |
| NZ (1) | NZ286013A (no) |
| PL (1) | PL181628B1 (no) |
| PT (1) | PT728741E (no) |
| RU (1) | RU2159763C2 (no) |
| SI (1) | SI9600053B (no) |
| SK (1) | SK281876B6 (no) |
| TR (1) | TR199600129A2 (no) |
| TW (1) | TW357140B (no) |
| ZA (1) | ZA961314B (no) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19832009A1 (de) | 1998-07-16 | 2000-01-20 | Hoechst Marion Roussel De Gmbh | 2,5-Substituierte Benzolsulfonylharnstoffe und -thioharnstoffe, Verfahren zu ihrer Herstellung, ihre Verwendung und sie enthaltende pharamazeutische Präparate |
| US6436864B1 (en) | 1999-10-06 | 2002-08-20 | Sri International | Unsaturated nitrogenous compounds as electron donors for use with ziegler-natta catalysts |
| DE10129704A1 (de) * | 2001-06-22 | 2003-01-02 | Aventis Pharma Gmbh | Verwendung von Benzolsulfonyl(thio)harnstoffen in der Behandlung des septischen Schocks |
| CN101160285A (zh) * | 2005-03-17 | 2008-04-09 | 辉瑞大药厂 | 适用于治疗疼痛的n-(n-磺酰氨基甲基)环丙烷甲酰胺衍生物 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL141381B (nl) * | 1963-09-25 | 1974-03-15 | Hoechst Ag | Werkwijze voor het bereiden van geneesmiddelen met bloedsuikerspiegel verlagende werkzaamheid. |
| DE1198354B (de) * | 1963-09-25 | 1965-08-12 | Hoechst Ag | Verfahren zur Herstellung von Benzol-sulfonylharnstoffen |
| BE754454A (fr) * | 1969-08-06 | 1971-02-05 | Bayer Ag | Nouveaux composes hypoglycemiques du type d'arylsulfonylurees et d'arylsulfonylsemicarbazides contenant des groupes carbonamide |
| ES2098069T3 (es) * | 1993-02-23 | 1997-04-16 | Hoechst Ag | Bencenosulfonil-ureas y -tioureas sustituidas, procedimiento para su preparacion y su utilizacion como agentes farmaceuticos. |
| DE4341655A1 (de) * | 1993-12-07 | 1995-06-08 | Hoechst Ag | Aminosubstituierte Benzolsulfonylharnstoffe und -thioharnstoffe, Verfahren zu ihrer Herstellung und ihre Verwendung als Pharmazeutika |
-
1994
- 1994-02-20 ZA ZA961314A patent/ZA961314B/xx unknown
-
1995
- 1995-02-21 DE DE19505910A patent/DE19505910A1/de not_active Withdrawn
- 1995-12-29 HU HU9503931A patent/HU227308B1/hu not_active IP Right Cessation
-
1996
- 1996-01-29 PL PL96312529A patent/PL181628B1/pl not_active IP Right Cessation
- 1996-02-13 CN CN96102002A patent/CN1060767C/zh not_active Expired - Fee Related
- 1996-02-15 AT AT96102255T patent/ATE196467T1/de active
- 1996-02-15 DK DK96102255T patent/DK0728741T3/da active
- 1996-02-15 PT PT96102255T patent/PT728741E/pt unknown
- 1996-02-15 ES ES96102255T patent/ES2151614T3/es not_active Expired - Lifetime
- 1996-02-15 DE DE59605898T patent/DE59605898D1/de not_active Expired - Lifetime
- 1996-02-15 EP EP96102255A patent/EP0728741B1/de not_active Expired - Lifetime
- 1996-02-16 CA CA002169695A patent/CA2169695C/en not_active Expired - Fee Related
- 1996-02-16 US US08/601,109 patent/US5633239A/en not_active Expired - Lifetime
- 1996-02-16 BR BR9600773A patent/BR9600773A/pt not_active IP Right Cessation
- 1996-02-16 TR TR96/00129A patent/TR199600129A2/xx unknown
- 1996-02-17 MY MYPI96000635A patent/MY113432A/en unknown
- 1996-02-19 AU AU45600/96A patent/AU701278B2/en not_active Ceased
- 1996-02-19 SK SK222-96A patent/SK281876B6/sk not_active IP Right Cessation
- 1996-02-19 NZ NZ286013A patent/NZ286013A/en not_active IP Right Cessation
- 1996-02-19 HR HR960081A patent/HRP960081B1/xx not_active IP Right Cessation
- 1996-02-19 FI FI960740A patent/FI120392B/fi not_active IP Right Cessation
- 1996-02-19 AR AR33545296A patent/AR001352A1/es unknown
- 1996-02-19 CZ CZ1996486A patent/CZ291219B6/cs not_active IP Right Cessation
- 1996-02-19 IL IL11717996A patent/IL117179A/xx not_active IP Right Cessation
- 1996-02-20 RU RU96103250/04A patent/RU2159763C2/ru not_active IP Right Cessation
- 1996-02-20 NO NO960664A patent/NO305792B1/no not_active IP Right Cessation
- 1996-02-20 SI SI9600053A patent/SI9600053B/sl not_active IP Right Cessation
- 1996-02-21 JP JP03327496A patent/JP3905570B2/ja not_active Expired - Fee Related
- 1996-02-21 KR KR1019960004021A patent/KR100446566B1/ko not_active IP Right Cessation
- 1996-04-22 TW TW085104747A patent/TW357140B/zh not_active IP Right Cessation
-
2000
- 2000-10-20 GR GR20000402333T patent/GR3034646T3/el unknown
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FF | Patent granted | ||
| KB | Patent renewed | ||
| KB | Patent renewed | ||
| MM9K | Patent not in force due to non-payment of renewal fees |