ZA9610405B - New crystal modification of cdch a process for its preparation and pharmaceutical formulations comprising this modification - Google Patents

New crystal modification of cdch a process for its preparation and pharmaceutical formulations comprising this modification

Info

Publication number
ZA9610405B
ZA9610405B ZA9610405A ZA9610405A ZA9610405B ZA 9610405 B ZA9610405 B ZA 9610405B ZA 9610405 A ZA9610405 A ZA 9610405A ZA 9610405 A ZA9610405 A ZA 9610405A ZA 9610405 B ZA9610405 B ZA 9610405B
Authority
ZA
South Africa
Prior art keywords
modification
cdch
preparation
pharmaceutical formulations
new crystal
Prior art date
Application number
ZA9610405A
Other languages
English (en)
Inventor
Alfons Grunenberg
Patrick Bosche
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=7779831&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ZA9610405(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of ZA9610405B publication Critical patent/ZA9610405B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
ZA9610405A 1995-12-12 1996-12-11 New crystal modification of cdch a process for its preparation and pharmaceutical formulations comprising this modification ZA9610405B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19546249A DE19546249A1 (de) 1995-12-12 1995-12-12 Neue Kristallmodifikation des 1-Cyclopropyl-7-([S,S]-2,8-diazabicyclo[4,3,0]non-8-yl)-6-fluor-1,4-dihydro-8-methoxy-4-oxo-3-chinolincarbonsäure Hydrochlorid (CDCH), Verfahren zu dessen Herstellung und diese enthaltende pharmazeutische Zubereitungen

Publications (1)

Publication Number Publication Date
ZA9610405B true ZA9610405B (en) 1997-06-23

Family

ID=7779831

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA9610405A ZA9610405B (en) 1995-12-12 1996-12-11 New crystal modification of cdch a process for its preparation and pharmaceutical formulations comprising this modification

Country Status (42)

Country Link
US (1) US5849752A (esLanguage)
EP (1) EP0780390B1 (esLanguage)
JP (1) JP4104687B2 (esLanguage)
KR (1) KR100525146B1 (esLanguage)
CN (1) CN1061348C (esLanguage)
AR (1) AR005009A1 (esLanguage)
AT (1) ATE221531T1 (esLanguage)
AU (1) AU708006B2 (esLanguage)
BG (1) BG62258B1 (esLanguage)
BR (1) BR9605968A (esLanguage)
CA (1) CA2192418C (esLanguage)
CO (1) CO4480105A1 (esLanguage)
CU (1) CU22774A3 (esLanguage)
CZ (1) CZ288657B6 (esLanguage)
DE (2) DE19546249A1 (esLanguage)
DK (1) DK0780390T3 (esLanguage)
EE (1) EE03474B1 (esLanguage)
ES (1) ES2179910T3 (esLanguage)
HR (1) HRP960558B1 (esLanguage)
HU (1) HU226521B1 (esLanguage)
ID (1) ID22625A (esLanguage)
IL (1) IL119795A (esLanguage)
IN (1) IN185805B (esLanguage)
MA (1) MA24342A1 (esLanguage)
MY (1) MY117492A (esLanguage)
NL (1) NL300109I1 (esLanguage)
NO (1) NO306725B1 (esLanguage)
NZ (1) NZ299905A (esLanguage)
PL (1) PL184885B1 (esLanguage)
PT (1) PT780390E (esLanguage)
RO (1) RO119782B1 (esLanguage)
RU (1) RU2162468C2 (esLanguage)
SA (1) SA96170492B1 (esLanguage)
SG (1) SG47201A1 (esLanguage)
SI (1) SI0780390T1 (esLanguage)
SK (1) SK282805B6 (esLanguage)
SV (1) SV1996000109A (esLanguage)
TR (1) TR199600970A2 (esLanguage)
TW (1) TW411340B (esLanguage)
UA (1) UA35638C2 (esLanguage)
YU (1) YU49485B (esLanguage)
ZA (1) ZA9610405B (esLanguage)

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EP1017392B1 (de) * 1997-09-25 2002-07-17 Bayer Aktiengesellschaft Arzneimittelformulierung mit kontrollierter wirkstofffreisetzung
DE19751948A1 (de) * 1997-11-24 1999-05-27 Bayer Ag Verfahren zur Herstellung von 8-Methoxy-Chinoloncarbonsäuren
US6716830B2 (en) * 1998-09-30 2004-04-06 Alcon, Inc. Ophthalmic antibiotic compositions containing moxifloxacin
US6509327B1 (en) 1998-09-30 2003-01-21 Alcon Manufacturing, Ltd. Compositions and methods for treating otic, ophthalmic and nasal infections
US6395746B1 (en) 1998-09-30 2002-05-28 Alcon Manufacturing, Ltd. Methods of treating ophthalmic, otic and nasal infections and attendant inflammation
BR9915208A (pt) 1998-11-10 2001-07-31 Bayer Ag Preparado farmacêutico de moxifloxacina
DE19854357A1 (de) * 1998-11-25 2000-05-31 Bayer Ag Semi-Hydrochlorid von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicyclo/4.3.0/ -nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäure
DE19854356A1 (de) * 1998-11-25 2000-05-31 Bayer Ag Kristallmodifikation A von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicyclo-/4.3.0/nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäure
DE19854355A1 (de) * 1998-11-25 2000-05-31 Bayer Ag Kristallmodifikation B von 8-Cyan-1-cyclopropyl-7-(1S, 6S-2,8-diazabicyclo-/4.3.O/nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäure
DE19908449A1 (de) * 1999-02-26 2000-08-31 Bayer Ag Kristallmodifikation C von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicylo-[4.3.0]nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chino/incarbonsäure
AU2003278418A1 (en) * 2002-10-31 2004-05-25 Ranbaxy Laboratories Limited Amorphous moxifloxacin hydrochloride
DE602004022646D1 (de) * 2003-04-09 2009-10-01 Reddys Lab Ltd Dr Kristalline form iii von wasserfreiem moxifloxacin-hydrochlorid und ein verfahren zu seiner herstellung
EP1651630A1 (en) * 2003-08-05 2006-05-03 Matrix Laboratories Ltd An improved process for the preparation of moxifloxacin hydrochloride
ITMI20032259A1 (it) 2003-11-20 2005-05-21 Chemi Spa Nuovo polimorfo dell'acido 1-ciclopropil-7-(s,s-2,8-diazabciclo-4.3.0-non-8-il)-6-fluoro-1,4-diidro-8-metossi-4-oxo-chinolin carbossilico cloridrato e metodi per la sua preparazione
WO2005054240A1 (en) * 2003-11-20 2005-06-16 Chemi Spa Polymorphs of 1-cyclopropyl-7-([s,s]-2,8-diazadicyclo[4.3.0]non-8-yl)-6-fluoro-1,4-dihydro-8-methoxy-4-oxo-3-quinoline carboxylic acid hydrochloride and methods for the preparation thereof
US7491725B2 (en) 2004-02-06 2009-02-17 Bristol-Myers Squibb Company Process for preparing 2-aminothiazole-5-aromatic carboxamides as kinase inhibitors
DE102004015981A1 (de) * 2004-04-01 2005-10-20 Bayer Healthcare Ag Neue kirstalline Form von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicyclo[4.3.0]nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäure
DE102004063347A1 (de) * 2004-12-23 2006-07-13 Stada Arzneimittel Ag Gebrauchsfertige Gemcitabinlösungen und Gemcitabinlösungskonzentrate
WO2007033515A1 (fr) * 2005-09-21 2007-03-29 Shenzhen Tys R & D Co., Ltd. Formulation orale contenant de la moxifloxacine et son procédé de préparation
GB0612422D0 (en) * 2006-06-23 2006-08-02 Generics Uk Ltd Novel hydrate form
CA2655061A1 (en) 2006-06-27 2008-01-03 Sandoz Ag New method for salt preparation
ES2303768B1 (es) * 2006-09-08 2009-06-05 Quimica Sintetica, S.A. Nueva forma cristalina de moxifloxacino clorhidrato.
CA2669427A1 (en) * 2006-11-13 2008-05-22 Cipla Limited Process for the synthesis of moxifloxacin hydrochloride
EP1992626A1 (en) * 2007-05-10 2008-11-19 Sandoz AG Process for the preparation of moxifloxacin hydrochloride
EP2083010A1 (en) * 2008-01-08 2009-07-29 Chemo Ibérica, S.A. Polymorphic Forms of Moxifloxacin hydrochloride and processes for preparation thereof
EP2154137A1 (en) 2008-08-04 2010-02-17 Chemo Ibérica, S.A. Crystalline form of moxifloxacin base
EA201170545A1 (ru) * 2008-10-09 2012-01-30 Абды Ибрахым Иладж Санайи Ве Тыджарет Аноным Сыркеты Применение органических растворителей в способе влажного гранулирования моксифлоксацина
WO2010052726A1 (en) * 2008-11-06 2010-05-14 Hetero Research Foundation Novel polymorph of moxifloxacin hydrochloride
PL2364141T5 (pl) 2008-12-08 2018-02-28 Ratiopharm Gmbh Kompaktorowana moksyfloksacyna
MX2011012134A (es) 2009-05-15 2012-02-08 Redx Pharma Ltd Derivados de farmaco de oxido-reduccion.
WO2011121596A2 (en) * 2010-04-01 2011-10-06 Neuland Laboratories Ltd. Crystal modification of moxifloxacin hydrochloride
BRPI1106900A2 (pt) 2011-12-26 2013-11-05 Ems Sa Composição farmacêutica sólida compreendendo antibótico da familia das quinolonas e processo de sua obtenção
FR2992218B1 (fr) 2012-06-22 2015-01-23 Rivopharm Sa Composition pharmaceutique de chlorhydrate de moxifloxacine et procede de preparation
CN102924449B (zh) * 2012-10-30 2015-08-12 重庆福安药业集团庆余堂制药有限公司 盐酸莫西沙星h晶型及其制备方法和药物组合物
EP2928892B1 (en) 2012-12-04 2018-03-21 Mankind Pharma Ltd. An improved process for the preparation of moxifloxacin hydrochloride
RU2561037C2 (ru) * 2013-02-07 2015-08-20 Открытое акционерное общество "Химико-фармацевтический комбинат "АКРИХИН" (ОАО "АКРИХИН") Антибактериальная фармацевтическая композиция и способ ее получения
KR102237887B1 (ko) 2013-03-15 2021-04-07 멜린타 서브시디어리 코프. 항생제를 사용하여 과체중 및 비만 환자에서 감염을 치료하는 방법

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DE3601567A1 (de) * 1986-01-21 1987-07-23 Bayer Ag 7-(azabicycloalkyl)-chinoloncarbonsaeure- und -naphthyridon-carbonsaeure-derivate
AU618235B2 (en) * 1986-03-31 1991-12-19 Sankyo Company Limited Quinoline-3-carboxylic acid derivatives, their preparation and use
AU609974B2 (en) * 1988-05-18 1991-05-09 Warner-Lambert Company Improved process for the preparation of 5-amino-7- (substituted amino)-quinoline-3-carboxylic acids
DE3910663A1 (de) * 1989-04-03 1990-10-04 Bayer Ag 5-alkylchinoloncarbonsaeuren
RO108347B1 (ro) * 1989-10-30 1994-04-28 Bellon Labor Sa Roger DERIVATI DE BENZO-(b)-NAFTIRIDIN-1,8 SI PROCEDEU DE PREPARARE A ACESTORA
TW209865B (esLanguage) 1992-01-10 1993-07-21 Bayer Ag
WO1993015070A1 (fr) * 1992-01-31 1993-08-05 Chugai Seiyaku Kabushiki Kaisha Cristal d'hydrate de derive d'acide quinolonecarboxylique
DE4234078A1 (de) * 1992-10-09 1994-04-14 Bayer Ag Chinoloncarbonsäuren
CA2112165C (en) * 1992-12-25 2003-04-08 Makoto Takemura Bicyclic amine derivatives
ZA946853B (en) * 1993-09-10 1995-04-24 Daiichi Seiyaku Co Crystals of antimicrobial compound.
ATE170400T1 (de) * 1994-04-07 1998-09-15 Pfizer Verwendung von trovafloxacin oder dessen derivaten zur herstellung eines arzneimittels zur behandlung von h.pylori infektionen

Also Published As

Publication number Publication date
EE9600201A (et) 1997-06-16
AU7421696A (en) 1997-06-19
HU226521B1 (en) 2009-03-30
BG62258B1 (bg) 1999-06-30
JP4104687B2 (ja) 2008-06-18
DE19546249A1 (de) 1997-06-19
AU708006B2 (en) 1999-07-29
EP0780390A1 (de) 1997-06-25
CA2192418A1 (en) 1997-06-13
NO965298L (no) 1997-06-13
KR100525146B1 (ko) 2006-01-27
SK282805B6 (sk) 2002-12-03
HUP9603428A3 (en) 1997-10-28
US5849752A (en) 1998-12-15
DE59609501D1 (de) 2002-09-05
CN1160052A (zh) 1997-09-24
HUP9603428A2 (en) 1997-08-28
HRP960558A2 (en) 1998-02-28
CZ364696A3 (en) 1997-07-16
AR005009A1 (es) 1999-04-07
HRP960558B1 (en) 2002-04-30
RU2162468C2 (ru) 2001-01-27
SG47201A1 (en) 1998-03-20
CO4480105A1 (es) 1997-07-09
TW411340B (en) 2000-11-11
YU49485B (sh) 2006-08-17
EE03474B1 (et) 2001-08-15
CN1061348C (zh) 2001-01-31
IL119795A (en) 1998-12-27
NO306725B1 (no) 1999-12-13
JPH09169757A (ja) 1997-06-30
ATE221531T1 (de) 2002-08-15
IL119795A0 (en) 1997-03-18
SK159196A3 (en) 1997-10-08
KR970042550A (ko) 1997-07-24
MY117492A (en) 2004-07-31
PL317415A1 (en) 1997-06-23
YU65096A (sh) 1998-12-23
CA2192418C (en) 2001-06-12
MX9606325A (es) 1997-10-31
DK0780390T3 (da) 2002-11-11
RO119782B1 (ro) 2005-03-30
NZ299905A (en) 1998-09-24
SA96170492B1 (ar) 2006-05-23
NL300109I1 (nl) 2003-02-03
SI0780390T1 (en) 2002-10-31
NO965298D0 (no) 1996-12-11
CU22774A3 (es) 2002-07-24
ID22625A (id) 1999-12-02
UA35638C2 (uk) 2001-04-16
HU9603428D0 (en) 1997-01-28
IN185805B (esLanguage) 2001-05-05
TR199600970A2 (tr) 1997-06-21
EP0780390B1 (de) 2002-07-31
PL184885B1 (pl) 2003-01-31
BR9605968A (pt) 1998-08-18
SV1996000109A (es) 1997-10-23
ES2179910T3 (es) 2003-02-01
BG101043A (en) 1998-04-30
PT780390E (pt) 2002-11-29
MA24342A1 (fr) 1998-07-01
CZ288657B6 (cs) 2001-08-15

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