ZA95960B - Use of interleukin-12 antagonists in the treatment of autoimmune diseases - Google Patents

Use of interleukin-12 antagonists in the treatment of autoimmune diseases

Info

Publication number
ZA95960B
ZA95960B ZA95960A ZA95960A ZA95960B ZA 95960 B ZA95960 B ZA 95960B ZA 95960 A ZA95960 A ZA 95960A ZA 95960 A ZA95960 A ZA 95960A ZA 95960 B ZA95960 B ZA 95960B
Authority
ZA
South Africa
Prior art keywords
autoimmune
treatment
interleukin
antagonists
autoimmune diseases
Prior art date
Application number
ZA95960A
Other languages
English (en)
Inventor
John P Leonard
Samuel Goldman
Richard O'hara Jr
Original Assignee
Genetics Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22791827&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ZA95960(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Genetics Inst filed Critical Genetics Inst
Publication of ZA95960B publication Critical patent/ZA95960B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/20—Interleukins [IL]
    • A61K38/208—IL-12
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244—Interleukins [IL]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Molecular Biology (AREA)
  • Emergency Medicine (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Epidemiology (AREA)
  • Endocrinology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Ophthalmology & Optometry (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
ZA95960A 1994-03-14 1995-02-07 Use of interleukin-12 antagonists in the treatment of autoimmune diseases ZA95960B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US21262994A 1994-03-14 1994-03-14

Publications (1)

Publication Number Publication Date
ZA95960B true ZA95960B (en) 1995-10-10

Family

ID=22791827

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA95960A ZA95960B (en) 1994-03-14 1995-02-07 Use of interleukin-12 antagonists in the treatment of autoimmune diseases

Country Status (14)

Country Link
US (1) US6338848B1 (fr)
EP (4) EP1179348A3 (fr)
JP (1) JP3798426B2 (fr)
AT (1) ATE217533T1 (fr)
AU (1) AU689236B2 (fr)
CA (1) CA2185565C (fr)
DE (1) DE69526728T3 (fr)
DK (1) DK0750509T4 (fr)
ES (1) ES2173953T5 (fr)
IL (1) IL112677A (fr)
PT (1) PT750509E (fr)
TW (1) TW400233B (fr)
WO (1) WO1995024918A1 (fr)
ZA (1) ZA95960B (fr)

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US6054487A (en) * 1997-03-18 2000-04-25 Basf Aktiengesellschaft Methods and compositions for modulating responsiveness to corticosteroids
US7229841B2 (en) 2001-04-30 2007-06-12 Cytimmune Sciences, Inc. Colloidal metal compositions and methods
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EP2168984B1 (fr) * 1999-03-25 2012-08-29 Abbott GmbH & Co. KG Anticorps humains qui se lient au IL-12 humain et procédé de fabrication
JP4676049B2 (ja) * 1999-07-21 2011-04-27 生化学工業株式会社 Ｉｌ−１２産生抑制剤
US6346247B1 (en) * 1999-10-28 2002-02-12 Promega Corporation Prevention and treatment of autoimmune disease with luminally administered polyclonal antibodies
US7115712B1 (en) 1999-12-02 2006-10-03 Maxygen, Inc. Cytokine polypeptides
US8080247B2 (en) 2000-08-07 2011-12-20 Janssen Biotech, Inc. Anti-IL-12 antibodies
US6902734B2 (en) 2000-08-07 2005-06-07 Centocor, Inc. Anti-IL-12 antibodies and compositions thereof
EP1494710A4 (fr) * 2002-03-26 2007-03-21 Centocor Inc Proteines derivees de l'immunoglobuline liees au diabete, compositions, methodes et utilisations relatives a ces proteines
WO2005065121A2 (fr) 2003-12-02 2005-07-21 Cytimmune Sciences, Inc. Procedes et compositions de production d'anticorps monoclonaux
GB0329146D0 (en) * 2003-12-16 2004-01-21 Glaxosmithkline Biolog Sa Vaccine
US20070178520A1 (en) * 2004-02-27 2007-08-02 Barbara Wolff-Winiski Screening assay for modulators of interaction between interleukin-12 and/or -23 with their receptors
DK2299275T3 (en) * 2004-07-30 2018-05-07 Adeza Biomedical Corp Classification of oncofetal fetronectin level for pregnancy-related indications
EP2500355A3 (fr) 2005-08-19 2012-10-24 Abbott Laboratories Immunoglobuline à double domaine variable et ses utilisations
EP1928506A4 (fr) 2005-08-19 2009-10-21 Abbott Lab Immunoglobuline a deux domaines variables et utilisations de celle-ci
US7612181B2 (en) 2005-08-19 2009-11-03 Abbott Laboratories Dual variable domain immunoglobulin and uses thereof
RU2475265C2 (ru) 2007-01-16 2013-02-20 Эбботт Лэборетриз Способы лечения псориаза
KR20100014674A (ko) 2007-03-29 2010-02-10 아보트 러보러터리즈 결정성 항-사람 ｉｌ-12 항체
TW201513883A (zh) 2008-03-18 2015-04-16 Abbvie Inc 治療牛皮癬的方法
AU2009241589B2 (en) 2008-04-29 2013-10-10 Abbvie Inc. Dual variable domain immunoglobulins and uses thereof
EP3002299A1 (fr) 2008-06-03 2016-04-06 AbbVie Inc. Immunoglobulines à deux domaines variables et leurs utilisations
MX2010013236A (es) 2008-06-03 2011-02-24 Abbott Lab Inmunoglobulinas de dominio variable doble y usos de las mismas.
MX2010014574A (es) 2008-07-08 2011-04-27 Abbott Lab Inmunoglobulinas de dominio variable dual para prostaglandina e2 y usos de las mismas.
US20110243938A1 (en) * 2008-09-30 2011-10-06 Baylor Research Intitute Methods to Reduce B-Helper T Cells to Treat Autoimmune Diseases
CN104398471A (zh) * 2008-11-28 2015-03-11 Abbvie公司 稳定的抗体组合物和用于稳定其的方法
PE20121530A1 (es) 2009-09-01 2012-12-22 Abbvie Inc Inmunoglobulinas con dominio variable dual
MX2012003138A (es) 2009-09-14 2012-07-04 Abbott Lab Y Abbott Gmbh & Co Kg Metodos para tratar la psoriasis.
US8716450B2 (en) 2009-10-15 2014-05-06 Abbvie Inc. Dual variable domain immunoglobulins and uses thereof
UY32979A (es) 2009-10-28 2011-02-28 Abbott Lab Inmunoglobulinas con dominio variable dual y usos de las mismas
WO2011051466A1 (fr) 2009-11-02 2011-05-05 Novartis Ag Molécules de liaison anti-idiotypiques à base de fibronectine et leurs utilisations
US20120009196A1 (en) 2010-07-08 2012-01-12 Abbott Laboratories Monoclonal antibodies against hepatitis c virus core protein
UY33492A (es) 2010-07-09 2012-01-31 Abbott Lab Inmunoglobulinas con dominio variable dual y usos de las mismas
RU2013109275A (ru) 2010-08-03 2014-09-10 Эббви Инк. Иммуноглобулины с двумя вариабельными доменами и их применение
KR20130139884A (ko) 2010-08-26 2013-12-23 애브비 인코포레이티드 이원 가변 도메인 면역글로불린 및 이의 용도
US8962317B2 (en) 2010-09-28 2015-02-24 Neumedicines, Inc. Uses of IL-12 and the IL-12 receptor positive cell in tissue repair and regeneration
US8853365B2 (en) 2010-12-21 2014-10-07 Abbvie Inc. Dual variable domain immunnoglobulins and uses thereof
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CA2843014C (fr) * 2011-07-27 2020-01-21 Neumedicines, Inc. Utilisation d'il-12 pour generer de l'erythropoietine endogene
TW201333035A (zh) 2011-12-30 2013-08-16 Abbvie Inc 針對ｉｌ－１３及／或ｉｌ－１７之雙特異性結合蛋白
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Also Published As

Publication number Publication date
ES2173953T5 (es) 2007-03-01
DK0750509T3 (da) 2002-07-08
IL112677A0 (en) 1995-05-26
AU1974995A (en) 1995-10-03
DE69526728T2 (de) 2002-11-21
TW400233B (en) 2000-08-01
IL112677A (en) 2000-01-31
EP0750509B1 (fr) 2002-05-15
DE69526728T3 (de) 2007-01-04
ES2173953T3 (es) 2002-11-01
JP3798426B2 (ja) 2006-07-19
PT750509E (pt) 2002-08-30
AU689236B2 (en) 1998-03-26
EP0750509B2 (fr) 2006-06-14
EP1179348A3 (fr) 2003-12-03
US6338848B1 (en) 2002-01-15
EP0750509A1 (fr) 1997-01-02
DE69526728D1 (de) 2002-06-20
CA2185565A1 (fr) 1995-09-21
ATE217533T1 (de) 2002-06-15
CA2185565C (fr) 2009-02-03
EP2201959A2 (fr) 2010-06-30
DK0750509T4 (da) 2006-10-16
WO1995024918A1 (fr) 1995-09-21
EP2311484A1 (fr) 2011-04-20
JPH09510444A (ja) 1997-10-21
EP1179348A2 (fr) 2002-02-13
EP2201959A3 (fr) 2011-03-16

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