ZA956925B - Estradiol-TTS having water-binding additives - Google Patents

Estradiol-TTS having water-binding additives

Info

Publication number
ZA956925B
ZA956925B ZA956925A ZA956925A ZA956925B ZA 956925 B ZA956925 B ZA 956925B ZA 956925 A ZA956925 A ZA 956925A ZA 956925 A ZA956925 A ZA 956925A ZA 956925 B ZA956925 B ZA 956925B
Authority
ZA
South Africa
Prior art keywords
pct
water
estradiol
tts
matrix
Prior art date
Application number
ZA956925A
Other languages
English (en)
Inventor
Walter Mueller
Michael Horstmann
Original Assignee
Lohmann Therapie Syst Lts
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lohmann Therapie Syst Lts filed Critical Lohmann Therapie Syst Lts
Publication of ZA956925B publication Critical patent/ZA956925B/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7069Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained otherwise than by reactions only involving carbon to carbon unsaturated bonds, e.g. polysiloxane, polyesters, polyurethane, polyethylene oxide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/12Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/24Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/30Oestrogens
ZA956925A 1994-08-20 1995-08-18 Estradiol-TTS having water-binding additives ZA956925B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4429667A DE4429667C2 (de) 1994-08-20 1994-08-20 Estradiol-TTS mit wasserbindenden Zusätzen und Verfahren zu seiner Herstellung

Publications (1)

Publication Number Publication Date
ZA956925B true ZA956925B (en) 1996-03-25

Family

ID=6526231

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA956925A ZA956925B (en) 1994-08-20 1995-08-18 Estradiol-TTS having water-binding additives

Country Status (22)

Country Link
US (1) US5902602A (xx)
EP (1) EP0776199B1 (xx)
JP (1) JP3825799B2 (xx)
KR (1) KR100401136B1 (xx)
CN (1) CN1078461C (xx)
AT (1) ATE185067T1 (xx)
AU (1) AU695970B2 (xx)
CZ (1) CZ289397B6 (xx)
DE (2) DE4429667C2 (xx)
DK (1) DK0776199T3 (xx)
ES (1) ES2139932T3 (xx)
FI (1) FI118720B (xx)
GR (1) GR3032218T3 (xx)
HU (1) HU226959B1 (xx)
IL (1) IL114949A (xx)
MX (1) MX9701302A (xx)
NO (1) NO313984B1 (xx)
NZ (1) NZ291813A (xx)
PL (1) PL180965B1 (xx)
SK (1) SK281626B6 (xx)
WO (1) WO1996005814A1 (xx)
ZA (1) ZA956925B (xx)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5698217A (en) * 1995-05-31 1997-12-16 Minnesota Mining And Manufacturing Company Transdermal drug delivery device containing a desiccant
DE19600347A1 (de) * 1996-01-08 1997-07-10 Lohmann Therapie Syst Lts Hauthaftende pharmazeutische Zubereitung, insbesondere TTS zur Abgabe von 17-beta-Estradiol an den menschlichen Organismus
DE19713141A1 (de) * 1996-03-29 1997-10-30 Labtec Gmbh Transdermales System mit Melatonin
DE19827732A1 (de) * 1998-06-22 1999-12-23 Rottapharm Bv Transdermales System vom Matrix-Typ zur Abgabe von Wirkstoffen mit einer hohen Abgaberate von Steroid-Hormonen und die Verwendung eines derartigen Systems zur Hormonersatztherapie
US10493049B2 (en) 2016-02-10 2019-12-03 Niracle LLC Applicator-based transdermal drug delivery system for administration of drugs in combination with topical formulations
CN117545474A (zh) 2021-11-08 2024-02-09 李维庸 一种用于向患者递送药物的透皮给药系统

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE12731T1 (de) * 1979-01-11 1985-05-15 Key Pharma Polymere diffusionsmatrix und verfahren zu deren herstellung.
US4438139A (en) * 1979-08-14 1984-03-20 Key Pharmaceuticals, Inc. Polymeric diffusion matrix containing estrogens
CA1163559A (en) * 1980-07-09 1984-03-13 Alec D. Keith Polymeric diffusion matrix for administration of drugs
DE3333240A1 (de) * 1983-09-12 1985-03-28 Schering AG, 1000 Berlin und 4709 Bergkamen Mittel zur transdermalen applikation von arzneimittelwirkstoffen
ZA853488B (en) * 1984-05-10 1986-12-30 American Home Prod Transdermal dosage form
US4810499A (en) * 1984-10-01 1989-03-07 Biotek, Inc. Transdermal drug delivery system and method
US4788062A (en) * 1987-02-26 1988-11-29 Alza Corporation Transdermal administration of progesterone, estradiol esters, and mixtures thereof
US4816258A (en) * 1987-02-26 1989-03-28 Alza Corporation Transdermal contraceptive formulations
US4764379A (en) * 1987-08-24 1988-08-16 Alza Corporation Transdermal drug delivery device with dual permeation enhancers
US4863738A (en) * 1987-11-23 1989-09-05 Alza Corporation Skin permeation enhancer compositions using glycerol monooleate
US4855294A (en) * 1988-09-06 1989-08-08 Theratech, Inc. Method for reducing skin irritation associated with drug/penetration enhancer compositions
DD279818A1 (de) * 1989-02-06 1990-06-20 Jenapharm Veb Verfahren zur herstellung eines medizinischen pflasters
DE3933460A1 (de) * 1989-10-06 1991-04-18 Lohmann Therapie Syst Lts Oestrogenhaltiges wirkstoffpflaster
AR246186A1 (es) * 1989-11-17 1994-07-29 Beta Pharm Co Procedimiento para fabricar un dispositivo para administrar estradiol por via transdermica.
DE4210165A1 (de) * 1991-07-30 1993-02-04 Schering Ag Transdermale therapeutische systeme
US5518734A (en) * 1991-09-25 1996-05-21 Beta Pharmaceuticals Co. Transdermal delivery system for estradiol and process for manufacturing said device
DE4210711A1 (de) * 1991-10-31 1993-05-06 Schering Ag Berlin Und Bergkamen, 1000 Berlin, De Transdermale therapeutische systeme mit kristallisationsinhibitoren
WO1993025168A1 (en) * 1992-06-11 1993-12-23 Theratech, Inc. The use of glycerin in moderating transdermal drug delivery
US5683711A (en) * 1993-04-20 1997-11-04 Hexal Pharma Gmbh Active ingredient patch

Also Published As

Publication number Publication date
IL114949A (en) 1998-12-27
SK22097A3 (en) 1997-07-09
NO970360D0 (no) 1997-01-28
IL114949A0 (en) 1995-12-08
US5902602A (en) 1999-05-11
DK0776199T3 (da) 2000-04-10
KR100401136B1 (ko) 2004-03-31
DE4429667C2 (de) 1996-07-11
JP3825799B2 (ja) 2006-09-27
FI118720B (fi) 2008-02-29
PL180965B1 (pl) 2001-05-31
CN1078461C (zh) 2002-01-30
NZ291813A (en) 1998-01-26
HU226959B1 (en) 2010-03-29
GR3032218T3 (en) 2000-04-27
DE4429667A1 (de) 1996-02-22
FI970701A (fi) 1997-02-19
AU695970B2 (en) 1998-08-27
DE59506962D1 (de) 1999-11-04
KR970705381A (ko) 1997-10-09
NO970360L (no) 1997-01-28
CZ289397B6 (cs) 2002-01-16
CN1155835A (zh) 1997-07-30
NO313984B1 (no) 2003-01-13
CZ50997A3 (en) 1997-06-11
WO1996005814A1 (de) 1996-02-29
EP0776199A1 (de) 1997-06-04
EP0776199B1 (de) 1999-09-29
JPH10504313A (ja) 1998-04-28
PL319013A1 (en) 1997-07-21
ES2139932T3 (es) 2000-02-16
HUT77085A (hu) 1998-03-02
MX9701302A (es) 1998-05-31
SK281626B6 (sk) 2001-05-10
AU3344995A (en) 1996-03-14
FI970701A0 (fi) 1997-02-19
ATE185067T1 (de) 1999-10-15

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