ZA956327B - Novel pyrrolocarbazoles - Google Patents
Novel pyrrolocarbazolesInfo
- Publication number
- ZA956327B ZA956327B ZA956327A ZA956327A ZA956327B ZA 956327 B ZA956327 B ZA 956327B ZA 956327 A ZA956327 A ZA 956327A ZA 956327 A ZA956327 A ZA 956327A ZA 956327 B ZA956327 B ZA 956327B
- Authority
- ZA
- South Africa
- Prior art keywords
- pyrrolocarbazoles
- novel
- lower alkyl
- hydrogen
- heteroaryl
- Prior art date
Links
- QNMMYUBZGLXCCK-UHFFFAOYSA-N pyrrolo[3,2-a]carbazole Chemical class N1=C2C=CC=CC2=C2C1=C1C=CN=C1C=C2 QNMMYUBZGLXCCK-UHFFFAOYSA-N 0.000 title 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 239000002246 antineoplastic agent Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229940127089 cytotoxic agent Drugs 0.000 abstract 1
- 125000001072 heteroaryl group Chemical group 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/06—Peri-condensed systems
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pyrrole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Steroid Compounds (AREA)
- Emulsifying, Dispersing, Foam-Producing Or Wetting Agents (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US28604394A | 1994-08-04 | 1994-08-04 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA956327B true ZA956327B (en) | 1996-02-04 |
Family
ID=23096813
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA956327A ZA956327B (en) | 1994-08-04 | 1995-07-28 | Novel pyrrolocarbazoles |
Country Status (29)
| Country | Link |
|---|---|
| US (1) | US5721267A (cs) |
| EP (1) | EP0695755B1 (cs) |
| JP (1) | JP2672290B2 (cs) |
| KR (1) | KR100326790B1 (cs) |
| CN (1) | CN1051551C (cs) |
| AT (1) | ATE172463T1 (cs) |
| AU (1) | AU692563B2 (cs) |
| BR (1) | BR9503536A (cs) |
| CA (1) | CA2155148A1 (cs) |
| CO (1) | CO4410329A1 (cs) |
| CZ (1) | CZ288583B6 (cs) |
| DE (1) | DE69505470T2 (cs) |
| DK (1) | DK0695755T3 (cs) |
| ES (1) | ES2123873T3 (cs) |
| FI (1) | FI111258B (cs) |
| HU (1) | HU225567B1 (cs) |
| IL (1) | IL114785A (cs) |
| MA (1) | MA23639A1 (cs) |
| MY (1) | MY117092A (cs) |
| NO (1) | NO304833B1 (cs) |
| NZ (1) | NZ272687A (cs) |
| PE (1) | PE34996A1 (cs) |
| PL (1) | PL180801B1 (cs) |
| RU (1) | RU2162089C2 (cs) |
| SA (1) | SA95160203B1 (cs) |
| TR (1) | TR199500954A1 (cs) |
| TW (1) | TW403652B (cs) |
| UY (1) | UY24010A1 (cs) |
| ZA (1) | ZA956327B (cs) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1283203B1 (it) * | 1996-03-07 | 1998-04-16 | Ausimont Spa | Composizioni estinguenti la fiamma |
| US6020298A (en) * | 1997-03-05 | 2000-02-01 | Ausimont S.P.A. | Solvent cleaning agents including additives of the formula Rf -CFX-L containing perfluoroalkylenic units |
| DE19744257B4 (de) * | 1997-10-07 | 2004-04-15 | Zentaris Gmbh | Beta-Carboline und deren Verwendung zur Behandlung von malignen und anderen, auf pathologischen Zellproliferationen beruhenden Erkrankungen |
| US7122679B2 (en) * | 2000-05-09 | 2006-10-17 | Cephalon, Inc. | Multicyclic compounds and the use thereof |
| US20050070591A1 (en) * | 2001-12-18 | 2005-03-31 | Fumihiko Kanai | Indole derivative |
| US7094798B1 (en) | 2002-04-26 | 2006-08-22 | Pfizer Inc | Inhibitors of checkpoint kinases (Wee1 and Chk1) |
| BR0309783A (pt) * | 2002-04-26 | 2005-03-22 | Warner Lambert Co | Inibidores de quinases de pontos de controlo (wee1 e chk1) |
| JP2012051804A (ja) * | 2008-12-26 | 2012-03-15 | Kyoto Univ | Ｅｇ５阻害剤 |
| RU2404983C1 (ru) * | 2009-06-08 | 2010-11-27 | Федеральное Государственное Образовательное Учреждение Высшего Профессионального Образования "Южный Федеральный Университет" | СПОСОБ ПОЛУЧЕНИЯ 2-R1-6-R2-5-АРИЛ-ПИРРОЛО[3,4-с]КАРБАЗОЛ-1,3(2Н,6Н)-ДИОНОВ |
| PL2975024T3 (pl) * | 2009-06-10 | 2018-09-28 | Chugai Seiyaku Kabushiki Kaisha | Związki tetracykliczne |
| US9365514B2 (en) | 2010-08-20 | 2016-06-14 | Chugai Seiyaku Kabushiki Kaisha | Composition comprising tetracyclic compound |
| ES2692664T3 (es) | 2012-09-25 | 2018-12-04 | Chugai Seiyaku Kabushiki Kaisha | Inhibidor de RET |
| KR101577098B1 (ko) | 2012-11-20 | 2015-12-14 | 주식회사 두산 | 유기 화합물 및 이를 포함하는 유기 전계 발광 소자 |
| KR20220042486A (ko) | 2014-04-25 | 2022-04-05 | 추가이 세이야쿠 가부시키가이샤 | 4환성 화합물의 신규 결정 |
| SG10202009484WA (en) | 2014-04-25 | 2020-11-27 | Chugai Pharmaceutical Co Ltd | Preparation containing tetracyclic compound at high dose |
| TWI765410B (zh) | 2014-08-08 | 2022-05-21 | 日商中外製藥股份有限公司 | ４環性化合物的非晶質體的用途 |
| EP3246047B1 (en) | 2015-01-16 | 2024-12-25 | Chugai Seiyaku Kabushiki Kaisha | Combination drug |
| EP3848361B1 (en) | 2018-09-04 | 2025-01-22 | Chugai Seiyaku Kabushiki Kaisha | Method of producing tetracyclic compound |
| KR102509614B1 (ko) * | 2022-08-09 | 2023-03-13 | 김학수 | 부직포 패널 제조방법 및 제조장치 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8611762D0 (en) * | 1986-05-14 | 1986-06-25 | Wellcome Found | Polycyclic biocidal compounds |
| US4785085A (en) * | 1986-11-21 | 1988-11-15 | Bristol-Myers Company | Rebeccamycin analogs |
| IL89167A (en) * | 1988-02-10 | 1994-02-27 | Hoffmann La Roche | Substituted pyrroles, their manufacture and pharmaceutical compositions containing them |
| DE3833008A1 (de) * | 1988-09-29 | 1990-04-05 | Goedecke Ag | Pyrrolocarbozol-derivate, verfahren zu deren herstellung und deren verwendung als arzneimittel |
| MC2096A1 (fr) * | 1989-02-23 | 1991-02-15 | Hoffmann La Roche | Pyrroles substitues |
| GB2239013B (en) * | 1989-11-01 | 1993-06-02 | Toyama Chemical Co Ltd | Novel isoindole derivatives and salts thereof,processes for producing the same and antitumor agent comprising the same |
| DE4005969A1 (de) * | 1990-02-26 | 1991-08-29 | Boehringer Mannheim Gmbh | Neue trisubstituierte pyrrole, verfahren zu ihrer herstellung sowie arzneimittel, die diese verbindungen enthalten |
| DE4217964A1 (de) * | 1992-05-30 | 1993-12-02 | Goedecke Ag | Indolocarbazol-Imide und deren Verwendung |
| AU678435B2 (en) * | 1993-05-10 | 1997-05-29 | F. Hoffmann-La Roche Ag | Substituted pyrroles |
| DE69409641T2 (de) * | 1993-05-28 | 1998-11-26 | Cephalon, Inc., West Chester, Pa. | Anwendung von indolocarbazol-derivaten zur behandlung von prostataerkrankungen |
-
1995
- 1995-07-21 EP EP95111472A patent/EP0695755B1/en not_active Expired - Lifetime
- 1995-07-21 DK DK95111472T patent/DK0695755T3/da active
- 1995-07-21 DE DE69505470T patent/DE69505470T2/de not_active Expired - Fee Related
- 1995-07-21 AT AT95111472T patent/ATE172463T1/de not_active IP Right Cessation
- 1995-07-21 ES ES95111472T patent/ES2123873T3/es not_active Expired - Lifetime
- 1995-07-25 TW TW084107708A patent/TW403652B/zh not_active IP Right Cessation
- 1995-07-27 AU AU27220/95A patent/AU692563B2/en not_active Ceased
- 1995-07-28 ZA ZA956327A patent/ZA956327B/xx unknown
- 1995-07-31 HU HU9502270A patent/HU225567B1/hu not_active IP Right Cessation
- 1995-07-31 NZ NZ272687A patent/NZ272687A/en unknown
- 1995-07-31 IL IL114785A patent/IL114785A/en not_active IP Right Cessation
- 1995-08-01 CA CA002155148A patent/CA2155148A1/en not_active Abandoned
- 1995-08-01 PE PE1995275075A patent/PE34996A1/es not_active Application Discontinuation
- 1995-08-02 MY MYPI95002255A patent/MY117092A/en unknown
- 1995-08-03 BR BR9503536A patent/BR9503536A/pt not_active IP Right Cessation
- 1995-08-03 MA MA23980A patent/MA23639A1/fr unknown
- 1995-08-03 RU RU95113107/04A patent/RU2162089C2/ru not_active IP Right Cessation
- 1995-08-03 TR TR95/00954A patent/TR199500954A1/xx unknown
- 1995-08-03 CN CN95108687A patent/CN1051551C/zh not_active Expired - Fee Related
- 1995-08-03 CO CO95034716A patent/CO4410329A1/es unknown
- 1995-08-03 KR KR1019950023928A patent/KR100326790B1/ko not_active Expired - Fee Related
- 1995-08-03 JP JP7197846A patent/JP2672290B2/ja not_active Expired - Fee Related
- 1995-08-03 UY UY24010A patent/UY24010A1/es not_active IP Right Cessation
- 1995-08-03 PL PL95309874A patent/PL180801B1/pl not_active IP Right Cessation
- 1995-08-03 NO NO953052A patent/NO304833B1/no unknown
- 1995-08-03 CZ CZ19951997A patent/CZ288583B6/cs not_active IP Right Cessation
- 1995-08-03 FI FI953710A patent/FI111258B/fi not_active IP Right Cessation
- 1995-08-27 SA SA95160203A patent/SA95160203B1/ar unknown
-
1997
- 1997-01-22 US US08/787,594 patent/US5721267A/en not_active Expired - Fee Related
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