ZA945435B - 1-aryloxy-3-alkylamino-2-propanol nitrate esters the use thereof and corresponding pharmaceutical composition - Google Patents

1-aryloxy-3-alkylamino-2-propanol nitrate esters the use thereof and corresponding pharmaceutical composition

Info

Publication number
ZA945435B
ZA945435B ZA945435A ZA945435A ZA945435B ZA 945435 B ZA945435 B ZA 945435B ZA 945435 A ZA945435 A ZA 945435A ZA 945435 A ZA945435 A ZA 945435A ZA 945435 B ZA945435 B ZA 945435B
Authority
ZA
South Africa
Prior art keywords
alkylamino
aryloxy
nitrate esters
pharmaceutical composition
corresponding pharmaceutical
Prior art date
Application number
ZA945435A
Other languages
English (en)
Inventor
Quinones Maria Prat
Sallent Joan Pi
Veit Dagmar Vedrilla
Original Assignee
Prodesfarma Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Prodesfarma Sa filed Critical Prodesfarma Sa
Publication of ZA945435B publication Critical patent/ZA945435B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C235/00Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/02Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C235/32Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
    • C07C235/34Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/02Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C217/04Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C217/28Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines
    • C07C217/30Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines having the oxygen atom of at least one of the etherified hydroxy groups further bound to a carbon atom of a six-membered aromatic ring
    • C07C217/32Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines having the oxygen atom of at least one of the etherified hydroxy groups further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring or condensed ring system containing that ring being further substituted

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Emergency Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
ZA945435A 1993-07-30 1994-07-22 1-aryloxy-3-alkylamino-2-propanol nitrate esters the use thereof and corresponding pharmaceutical composition ZA945435B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES09301721A ES2065291B1 (es) 1993-07-30 1993-07-30 "nitrato esteres de 1-ariloxi-3-alquilamino-2-propanoles, utilizacion y composicion farmaceutica correspondiente"

Publications (1)

Publication Number Publication Date
ZA945435B true ZA945435B (en) 1995-05-11

Family

ID=8282739

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA945435A ZA945435B (en) 1993-07-30 1994-07-22 1-aryloxy-3-alkylamino-2-propanol nitrate esters the use thereof and corresponding pharmaceutical composition

Country Status (18)

Country Link
US (2) US5502237A (de)
EP (1) EP0637583B1 (de)
JP (1) JP2777572B2 (de)
KR (1) KR950003262A (de)
AT (1) ATE146453T1 (de)
AU (1) AU666626B2 (de)
CA (1) CA2128671A1 (de)
CO (1) CO4290296A1 (de)
DE (1) DE69401177T2 (de)
DK (1) DK0637583T3 (de)
ES (1) ES2065291B1 (de)
GR (1) GR3022704T3 (de)
HU (1) HU214827B (de)
MX (1) MX9405660A (de)
NO (1) NO179746C (de)
NZ (1) NZ264118A (de)
PL (1) PL175707B1 (de)
ZA (1) ZA945435B (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1295694B1 (it) * 1996-11-14 1999-05-27 Nicox Sa Nitrossi derivati per la preparazione di medicamenti ad attivita antitrombinica
CN1083824C (zh) * 1999-09-24 2002-05-01 许景峰 具有心血管药理活性的合成化合物及制备方法
WO2005018561A2 (en) * 2003-08-20 2005-03-03 Nitromed, Inc. Nitrosated and nitrosylated cardiovascular compounds, compositions and methods of use
EP1691804B1 (de) 2003-12-02 2007-04-04 NicOx S.A. Nitrooxy-derivate von carvedilol und anderen betablockern als antihypertensiva
JP2007513113A (ja) * 2003-12-02 2007-05-24 ニコックス エス エイ 抗高血圧薬剤のニトロオキシ誘導体
WO2006052899A2 (en) * 2004-11-08 2006-05-18 Nitromed, Inc. Nitrosated and nitrosylated compounds, compositions and methods for the treatment of ophthalmic disorders
KR102324664B1 (ko) 2017-08-01 2021-11-10 주식회사 이강테크 듀얼 프레스를 이용한 복층유리 제조장치
KR102240153B1 (ko) 2017-08-01 2021-04-14 강흥섭 복층유리제조용 듀얼 프레싱장치
KR102240154B1 (ko) 2017-09-08 2021-04-14 강흥섭 유리판 다중 공급장치
KR200494614Y1 (ko) 2017-09-08 2021-11-17 주식회사 이강테크 복층 유리 제조에 적용되는 유리판 검사장치
KR20210020341A (ko) 2019-08-14 2021-02-24 주식회사 아이지스 복층 유리 제조를 위한 컨베어용 자동 분배 공급장치
KR102163495B1 (ko) 2019-08-22 2020-10-07 주식회사 아이지스 복층유리의 가스 주입을 갖는 더블 프레스 장치

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE354851B (de) * 1970-02-18 1973-03-26 Haessle Ab
DE2839475A1 (de) * 1978-09-11 1980-03-20 Dolorgiet Arzneimittelfabrik Isopropylamin-verbindungen, verfahren zu ihrer herstellung und sie enthaltende arzneimittel
JPS56113748A (en) * 1980-02-13 1981-09-07 Kowa Co Aminoethanol derivative and its preparation
US4387103A (en) * 1980-11-28 1983-06-07 American Hospital Supply Corporation Method for treatment or prophylaxis of cardiac disorders
JPS58109461A (ja) * 1981-12-24 1983-06-29 Kowa Co 新規ベンズアミド誘導体
DE3443998A1 (de) * 1984-12-01 1986-06-05 Boehringer Mannheim Gmbh, 6800 Mannheim Amino-propanol-derivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel sowie zwischenprodukte
NL8802276A (nl) * 1988-09-15 1990-04-02 Cedona Pharm Bv Geneesmiddel met relaxerende werking, dat als aktieve stof een nitraatester bevat.
IT1243367B (it) * 1990-07-26 1994-06-10 Italfarmaco Spa Derivati acidi benzoici sostituiti ad attivita' cardiovascolare
ES2026756A6 (es) * 1990-09-24 1992-05-01 Prodesfarma Sa Procedimiento para la obtencion de nitratos de 1-ariloxi-3 amino-2-propilo.

Also Published As

Publication number Publication date
US5502237A (en) 1996-03-26
EP0637583B1 (de) 1996-12-18
ES2065291B1 (es) 1995-10-01
NO179746C (no) 1996-12-11
NO942568D0 (no) 1994-07-07
DE69401177T2 (de) 1997-04-24
JP2777572B2 (ja) 1998-07-16
ES2065291A1 (es) 1995-02-01
EP0637583A1 (de) 1995-02-08
HU9402229D0 (en) 1994-09-28
NO179746B (no) 1996-09-02
DE69401177D1 (de) 1997-01-30
CO4290296A1 (es) 1996-04-17
CA2128671A1 (en) 1995-01-31
NZ264118A (en) 1995-04-27
DK0637583T3 (da) 1997-05-12
PL304406A1 (en) 1995-02-06
NO942568L (no) 1995-01-31
KR950003262A (ko) 1995-02-16
JPH0789910A (ja) 1995-04-04
MX9405660A (es) 1995-01-31
HU214827B (hu) 1998-06-29
US5639904A (en) 1997-06-17
GR3022704T3 (en) 1997-05-31
AU6743794A (en) 1995-02-09
ATE146453T1 (de) 1997-01-15
PL175707B1 (pl) 1999-01-29
HUT71813A (en) 1996-02-28
AU666626B2 (en) 1996-02-15

Similar Documents

Publication Publication Date Title
AU676884B2 (en) 1H-indole-3-acetamide sPLA2 inhibitors
CA2102209A1 (en) Novel Isoxazole Derivative and Salt Thereof
AU6379290A (en) Tricyclic carbapenem compounds
AU6601294A (en) Amide and urea derivatives having anti-hypercholesteremic activity, their preparation and their therapeutic uses
ZA945435B (en) 1-aryloxy-3-alkylamino-2-propanol nitrate esters the use thereof and corresponding pharmaceutical composition
EP0632031A4 (de)
TW256832B (de)
AU5504694A (en) Substituted amic acid derivatives
AU8226891A (en) Benzopyran derivative, production thereof, and pharmaceutical composition containing the same
IL90267A (en) Enantiomeric glutaramide diuretic agents, process for their preparation and compositions containing them
HU895648D0 (en) Process for the preparation of n,n-disubstituted diaryl-alkancarboxylic acid amide derivatives and pharmaceutical compositions containing such compounds
AU6231090A (en) N-azabicyclo(3.3.0)octane amides of aromatic acids
TW324719B (en) Succinamide compound, production thereof and use thereof
IE890257L (en) Hydrazides and hydroxamic acid derivatives