MX9405660A - Nitrato esteres de 1-ariloxi-3-alquilamino-2-propanoles, utilizacion ycomposicion farmaceutica correspondiente. - Google Patents

Nitrato esteres de 1-ariloxi-3-alquilamino-2-propanoles, utilizacion ycomposicion farmaceutica correspondiente.

Info

Publication number
MX9405660A
MX9405660A MX9405660A MX9405660A MX9405660A MX 9405660 A MX9405660 A MX 9405660A MX 9405660 A MX9405660 A MX 9405660A MX 9405660 A MX9405660 A MX 9405660A MX 9405660 A MX9405660 A MX 9405660A
Authority
MX
Mexico
Prior art keywords
aryloxi
propanols
alkylamino
nitrate esters
pharmaceutical composition
Prior art date
Application number
MX9405660A
Other languages
English (en)
Inventor
Maria Prat Quinones
Joan Pi Sallent
Dagmar Vedrilla Veit
Original Assignee
Prodesfarma Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Prodesfarma Sa filed Critical Prodesfarma Sa
Publication of MX9405660A publication Critical patent/MX9405660A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C235/32—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
    • C07C235/34—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/02—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C217/04—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C217/28—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines
    • C07C217/30—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines having the oxygen atom of at least one of the etherified hydroxy groups further bound to a carbon atom of a six-membered aromatic ring
    • C07C217/32—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines having the oxygen atom of at least one of the etherified hydroxy groups further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring or condensed ring system containing that ring being further substituted

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Emergency Medicine (AREA)
  • Epidemiology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

La presente invención se refiere a nitrato ésteres que son de fórmula I, asus enantiómeros y diastereoisómeros y sus sales terapéuticamenteaceptables, R1 representa una cadena de fórmula general II- (CH2)m - Z -R2, en la que: m es 1 ó 2; Z significa una función éter -O-, amida -CONH oéster -COO-; y R2 una cadena alquílica lineal o ramificada de 2 ó 3 átomosde carbono, que presenta como sustituyente al menos un grupo nitrooxi; yAr representa un anillo bencénico cuando Z representa la función éter oéster, y un anillo naftalénico cuando Z representa la función amida. Estoscompuestos son de utilidad para el tratamiento de afeccionescardiovasculares.
MX9405660A 1993-07-30 1994-07-25 Nitrato esteres de 1-ariloxi-3-alquilamino-2-propanoles, utilizacion ycomposicion farmaceutica correspondiente. MX9405660A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES09301721A ES2065291B1 (es) 1993-07-30 1993-07-30 "nitrato esteres de 1-ariloxi-3-alquilamino-2-propanoles, utilizacion y composicion farmaceutica correspondiente"

Publications (1)

Publication Number Publication Date
MX9405660A true MX9405660A (es) 1995-01-31

Family

ID=8282739

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9405660A MX9405660A (es) 1993-07-30 1994-07-25 Nitrato esteres de 1-ariloxi-3-alquilamino-2-propanoles, utilizacion ycomposicion farmaceutica correspondiente.

Country Status (18)

Country Link
US (2) US5502237A (es)
EP (1) EP0637583B1 (es)
JP (1) JP2777572B2 (es)
KR (1) KR950003262A (es)
AT (1) ATE146453T1 (es)
AU (1) AU666626B2 (es)
CA (1) CA2128671A1 (es)
CO (1) CO4290296A1 (es)
DE (1) DE69401177T2 (es)
DK (1) DK0637583T3 (es)
ES (1) ES2065291B1 (es)
GR (1) GR3022704T3 (es)
HU (1) HU214827B (es)
MX (1) MX9405660A (es)
NO (1) NO179746C (es)
NZ (1) NZ264118A (es)
PL (1) PL175707B1 (es)
ZA (1) ZA945435B (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1295694B1 (it) * 1996-11-14 1999-05-27 Nicox Sa Nitrossi derivati per la preparazione di medicamenti ad attivita antitrombinica
CN1083824C (zh) * 1999-09-24 2002-05-01 许景峰 具有心血管药理活性的合成化合物及制备方法
WO2005018561A2 (en) * 2003-08-20 2005-03-03 Nitromed, Inc. Nitrosated and nitrosylated cardiovascular compounds, compositions and methods of use
DE602004005748T2 (de) 2003-12-02 2007-12-27 Nicox S.A., Sophia Antipolis Nitrooxy-derivate von carvedilol und anderen betablockern als antihypertensiva
ES2320002T3 (es) * 2003-12-02 2009-05-18 Nicox S.A. Nitroxiderivados de farmacos antihipertensores.
EP1814535A4 (en) * 2004-11-08 2008-06-04 Nitromed Inc NITROSED AND NITROSYLATED COMPOUNDS, COMPOSITIONS AND METHODS OF TREATING EYE DISEASES
KR102240153B1 (ko) 2017-08-01 2021-04-14 강흥섭 복층유리제조용 듀얼 프레싱장치
KR102324664B1 (ko) 2017-08-01 2021-11-10 주식회사 이강테크 듀얼 프레스를 이용한 복층유리 제조장치
KR102240154B1 (ko) 2017-09-08 2021-04-14 강흥섭 유리판 다중 공급장치
KR200494614Y1 (ko) 2017-09-08 2021-11-17 주식회사 이강테크 복층 유리 제조에 적용되는 유리판 검사장치
KR20210020341A (ko) 2019-08-14 2021-02-24 주식회사 아이지스 복층 유리 제조를 위한 컨베어용 자동 분배 공급장치
KR102163495B1 (ko) 2019-08-22 2020-10-07 주식회사 아이지스 복층유리의 가스 주입을 갖는 더블 프레스 장치

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE354851B (es) * 1970-02-18 1973-03-26 Haessle Ab
DE2839475A1 (de) * 1978-09-11 1980-03-20 Dolorgiet Arzneimittelfabrik Isopropylamin-verbindungen, verfahren zu ihrer herstellung und sie enthaltende arzneimittel
JPS56113748A (en) * 1980-02-13 1981-09-07 Kowa Co Aminoethanol derivative and its preparation
US4387103A (en) * 1980-11-28 1983-06-07 American Hospital Supply Corporation Method for treatment or prophylaxis of cardiac disorders
JPS58109461A (ja) * 1981-12-24 1983-06-29 Kowa Co 新規ベンズアミド誘導体
DE3443998A1 (de) * 1984-12-01 1986-06-05 Boehringer Mannheim Gmbh, 6800 Mannheim Amino-propanol-derivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel sowie zwischenprodukte
NL8802276A (nl) * 1988-09-15 1990-04-02 Cedona Pharm Bv Geneesmiddel met relaxerende werking, dat als aktieve stof een nitraatester bevat.
IT1243367B (it) * 1990-07-26 1994-06-10 Italfarmaco Spa Derivati acidi benzoici sostituiti ad attivita' cardiovascolare
ES2026756A6 (es) * 1990-09-24 1992-05-01 Prodesfarma Sa Procedimiento para la obtencion de nitratos de 1-ariloxi-3 amino-2-propilo.

Also Published As

Publication number Publication date
US5502237A (en) 1996-03-26
ES2065291B1 (es) 1995-10-01
KR950003262A (ko) 1995-02-16
NO942568D0 (no) 1994-07-07
EP0637583A1 (en) 1995-02-08
JPH0789910A (ja) 1995-04-04
PL304406A1 (en) 1995-02-06
HU9402229D0 (en) 1994-09-28
DK0637583T3 (da) 1997-05-12
US5639904A (en) 1997-06-17
GR3022704T3 (en) 1997-05-31
PL175707B1 (pl) 1999-01-29
CO4290296A1 (es) 1996-04-17
NZ264118A (en) 1995-04-27
AU6743794A (en) 1995-02-09
NO179746B (no) 1996-09-02
ATE146453T1 (de) 1997-01-15
NO942568L (no) 1995-01-31
AU666626B2 (en) 1996-02-15
JP2777572B2 (ja) 1998-07-16
NO179746C (no) 1996-12-11
HU214827B (hu) 1998-06-29
CA2128671A1 (en) 1995-01-31
DE69401177T2 (de) 1997-04-24
DE69401177D1 (de) 1997-01-30
HUT71813A (en) 1996-02-28
ZA945435B (en) 1995-05-11
EP0637583B1 (en) 1996-12-18
ES2065291A1 (es) 1995-02-01

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Legal Events

Date Code Title Description
FG Grant or registration
MM Annulment or lapse due to non-payment of fees