ZA945415B - Method for precipitating natural avermectins - Google Patents

Method for precipitating natural avermectins

Info

Publication number
ZA945415B
ZA945415B ZA945415A ZA945415A ZA945415B ZA 945415 B ZA945415 B ZA 945415B ZA 945415 A ZA945415 A ZA 945415A ZA 945415 A ZA945415 A ZA 945415A ZA 945415 B ZA945415 B ZA 945415B
Authority
ZA
South Africa
Prior art keywords
pct
natural
avermectins
sec
precipitation
Prior art date
Application number
ZA945415A
Other languages
English (en)
Inventor
Abdullah R Ali
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of ZA945415B publication Critical patent/ZA945415B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/44—Preparation of O-glycosides, e.g. glucosides
    • C12P19/60—Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin
    • C12P19/62—Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin the hetero ring having eight or more ring members and only oxygen as ring hetero atoms, e.g. erythromycin, spiramycin, nystatin
    • C12P19/623—Avermectin; Milbemycin; Ivermectin; C-076
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/465—Streptomyces
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/886—Streptomyces

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
ZA945415A 1993-07-23 1994-07-22 Method for precipitating natural avermectins ZA945415B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US9674593A 1993-07-23 1993-07-23

Publications (1)

Publication Number Publication Date
ZA945415B true ZA945415B (en) 1996-01-22

Family

ID=22258886

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA945415A ZA945415B (en) 1993-07-23 1994-07-22 Method for precipitating natural avermectins

Country Status (16)

Country Link
US (2) US5686274A (ja)
EP (1) EP0710290B1 (ja)
JP (1) JP2828343B2 (ja)
AT (1) ATE175240T1 (ja)
AU (1) AU674743B2 (ja)
BR (1) BR9407141A (ja)
CA (1) CA2167186C (ja)
CO (1) CO4230201A1 (ja)
DE (1) DE69415675T2 (ja)
DK (1) DK0710290T3 (ja)
ES (1) ES2125446T3 (ja)
FI (2) FI112092B (ja)
GR (1) GR3029285T3 (ja)
NZ (1) NZ263615A (ja)
WO (1) WO1995003419A1 (ja)
ZA (1) ZA945415B (ja)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU4139797A (en) * 1997-06-09 1998-12-30 Nauchno-Proizvodstvennoye Obiedinenie "Farmbiomed" (streptomyces avermitilis) strain, method for separating avermectin complexe s and preparations for protecting plants and animals
KR100419554B1 (ko) * 1999-10-29 2004-02-19 주식회사유한양행 아버멕틴의 정제방법
US6872708B2 (en) * 2001-09-10 2005-03-29 Mitsukazu Matsumoto Local injection prescription
JP4373080B2 (ja) * 2002-12-24 2009-11-25 三井化学アグロ株式会社 ミルベマイシン類の精製法
US8080512B2 (en) * 2004-12-23 2011-12-20 J P Laboratories Pvt. Ltd. Process for preparing a detergent
CN103333214B (zh) * 2013-07-03 2015-08-12 大庆志飞生物化工有限公司 一种阿维菌素B2a精粉的制备方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI56187C (fi) * 1970-07-02 1979-12-10 Takeda Chemical Industries Ltd Foerfarande foer framstaellning av antibiotiskt aktiva estrar av makrolidglykosiderna b-5050 eller tetrahydro b-5050
US4017516A (en) * 1972-11-15 1977-04-12 Schering Corporation Novel monoesters of rosamicin
SE434277B (sv) * 1976-04-19 1984-07-16 Merck & Co Inc Sett att framstella nya antihelmintiskt verkande foreningar genom odling av streptomyces avermitilis
US4201861A (en) * 1977-10-03 1980-05-06 Merck & Co., Inc. Acyl derivatives of C-076 compounds
US4307085A (en) * 1979-11-09 1981-12-22 Schering Corporation Antibiotic AR-5 complex, antibiotics coproduced therewith and derivatives thereof
US4389397A (en) * 1980-08-04 1983-06-21 Merck & Co., Inc. Solubilization of ivermectin in water
US4399274A (en) * 1981-07-02 1983-08-16 Merck & Co., Inc. Isolation of non-ionic lipophilic materials on macroreticular polymeric absorbents
US4703009A (en) * 1983-03-08 1987-10-27 Merck & Co., Inc. RDNA cloning vector pVE1, deletion and hybrid mutants and recombinant derivatives thereof products and processes
ES8800986A1 (es) * 1985-07-27 1987-12-01 Pfizer Un procedimiento para la produccion de un nuevo derivado de avermectina
US5077348A (en) * 1986-10-31 1991-12-31 Toyo Ink Manufacturing Co., Ltd. Aqueous coating composition, process for the production thereof and aqueous coating
US5077398A (en) * 1986-11-18 1991-12-31 Merck & Co., Inc. Process for isolation of avermectin B1 components with improved purity and subsequent isolaton of B2 components
US5234831A (en) * 1987-01-23 1993-08-10 Pfizer Inc Cultures for production of B avermectins
JP2888586B2 (ja) * 1990-03-05 1999-05-10 社団法人北里研究所 エバーメクチンの特定成分を選択生産するための微生物およびその選択的製造法

Also Published As

Publication number Publication date
FI960304A (fi) 1996-01-22
FI960304A0 (fi) 1996-01-22
NZ263615A (en) 1997-08-22
ES2125446T3 (es) 1999-03-01
WO1995003419A1 (en) 1995-02-02
FI20030488A (fi) 2003-04-01
DE69415675D1 (de) 1999-02-11
CA2167186C (en) 1999-01-26
FI112092B (fi) 2003-10-31
CO4230201A1 (es) 1995-10-19
DE69415675T2 (de) 1999-05-20
DK0710290T3 (da) 1999-08-30
BR9407141A (pt) 1996-09-17
ATE175240T1 (de) 1999-01-15
US5905034A (en) 1999-05-18
CA2167186A1 (en) 1995-02-02
AU674743B2 (en) 1997-01-09
GR3029285T3 (en) 1999-05-28
US5686274A (en) 1997-11-11
JP2828343B2 (ja) 1998-11-25
EP0710290B1 (en) 1998-12-30
JPH08506966A (ja) 1996-07-30
FI112375B (fi) 2003-11-28
AU6436194A (en) 1995-02-20
EP0710290A1 (en) 1996-05-08

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