BR9406564A - Processo para a separação de uma enzima de uma solução aquosa - Google Patents

Processo para a separação de uma enzima de uma solução aquosa

Info

Publication number
BR9406564A
BR9406564A BR9406564-0A BR9406564A BR9406564A BR 9406564 A BR9406564 A BR 9406564A BR 9406564 A BR9406564 A BR 9406564A BR 9406564 A BR9406564 A BR 9406564A
Authority
BR
Brazil
Prior art keywords
enzyme
pct
aqueous solution
separation
sec
Prior art date
Application number
BR9406564-0A
Other languages
English (en)
Inventor
Birgitte Mahler Nilsson
Mads Aage Laustsen
Christine Pahle
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8093052&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR9406564(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Publication of BR9406564A publication Critical patent/BR9406564A/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/02General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length in solution
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/16Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/18Carboxylic ester hydrolases (3.1.1)
    • C12N9/20Triglyceride splitting, e.g. by means of lipase
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14Extraction; Separation; Purification
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/814Enzyme separation or purification
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/814Enzyme separation or purification
    • Y10S435/816Enzyme separation or purification by solubility

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Patente de Invenção "PROCESSO PARA A SEPARAçãO DE UMA ENZIMA DE UMA SOLUçãO AQUOSA". A presente invenção se refere a um processo de separação de uma enzima de uma solução aquosa compreendendo esta enzima na mistura com outras proteínas, e à recuperação da enzima desejada na forma cristalina.
BR9406564-0A 1993-04-02 1994-03-29 Processo para a separação de uma enzima de uma solução aquosa BR9406564A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DK93396A DK39693D0 (da) 1993-04-02 1993-04-02 Enzym
PCT/DK1994/000132 WO1994022903A1 (en) 1993-04-02 1994-03-29 Separation of proteins

Publications (1)

Publication Number Publication Date
BR9406564A true BR9406564A (pt) 1999-08-31

Family

ID=8093052

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9406564-0A BR9406564A (pt) 1993-04-02 1994-03-29 Processo para a separação de uma enzima de uma solução aquosa

Country Status (13)

Country Link
US (1) US5719048A (pt)
EP (1) EP0691982B2 (pt)
JP (1) JP3542601B2 (pt)
KR (1) KR960701082A (pt)
CN (1) CN1039244C (pt)
AT (1) ATE171189T1 (pt)
AU (1) AU6424294A (pt)
BR (1) BR9406564A (pt)
DE (1) DE69413389T2 (pt)
DK (2) DK39693D0 (pt)
ES (1) ES2124400T3 (pt)
FI (1) FI954648A (pt)
WO (1) WO1994022903A1 (pt)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE310745T1 (de) * 1996-03-08 2005-12-15 Novozymes As Kristallisation eines proteins mit einem schwefelsalz
US6031082A (en) * 1996-03-14 2000-02-29 Novo Nordisk A/S Increased yields of a crystallized protein by using a solid adsorption material
US5914141A (en) * 1997-03-11 1999-06-22 Alfacel S.A. Easy peeling wiener casings via use of enzymes
US6140475A (en) * 1997-04-11 2000-10-31 Altus Biologics Inc. Controlled dissolution crosslinked protein crystals
US20010046493A1 (en) * 2000-02-24 2001-11-29 Alex Margolin Lipase-containing composition and methods of use thereof
US7142464B2 (en) * 2003-04-29 2006-11-28 Saifun Semiconductors Ltd. Apparatus and methods for multi-level sensing in a memory array
ES2314646T3 (es) 2004-03-22 2009-03-16 Solvay Pharmaceuticals Gmbh Composiciones farmaceuticas por via de productos que contienen lipasa , en particular de pancreatina, que contienen tensioactivos.
US7823635B2 (en) * 2004-08-23 2010-11-02 Halliburton Energy Services, Inc. Downhole oil and water separator and method
EP1809320B1 (en) * 2004-10-14 2010-07-21 Altus Pharmaceuticals Inc. Compositions containing lipase; protease and amylase for treating pancreatic insufficiency
RU2413532C2 (ru) 2005-07-29 2011-03-10 Зольвай Фармасьютиклз Гмбх Способ получения стерилизованного порошкообразного панкреатина
US11266607B2 (en) 2005-08-15 2022-03-08 AbbVie Pharmaceuticals GmbH Process for the manufacture and use of pancreatin micropellet cores
US9198871B2 (en) 2005-08-15 2015-12-01 Abbott Products Gmbh Delayed release pancreatin compositions
US20100196344A1 (en) * 2005-10-14 2010-08-05 Cystic Fibrosis Foundation Therapeutics, Inc. Compositions and methods for treating pancreatic insufficiency
US10072256B2 (en) 2006-05-22 2018-09-11 Abbott Products Gmbh Process for separating and determining the viral load in a pancreatin sample
CN105112386A (zh) 2006-12-21 2015-12-02 诺维信公司 用于药物用途的脂肪酶变体
WO2011000924A1 (en) 2009-07-03 2011-01-06 Abbott Products Gmbh Spray-dried amylase, pharmaceutical preparations comprising the same and use
WO2014053359A1 (en) * 2012-10-05 2014-04-10 Arcelik Anonim Sirketi Refrigerator comprising water dispenser
AR100606A1 (es) 2014-05-27 2016-10-19 Novozymes As Variantes de lipasas y polinucleótidos que las codifican
EP3878957A1 (en) 2014-05-27 2021-09-15 Novozymes A/S Methods for producing lipases
EP4067485A3 (en) 2014-12-05 2023-01-04 Novozymes A/S Lipase variants and polynucleotides encoding same
CA3175255A1 (en) 2015-07-01 2017-01-05 Novozymes A/S Methods of reducing odor
EP3320089B1 (en) 2015-07-06 2021-06-16 Novozymes A/S Lipase variants and polynucleotides encoding same
CN108431217B (zh) 2015-12-01 2022-06-21 诺维信公司 用于产生脂肪酶的方法
US11326152B2 (en) 2016-07-18 2022-05-10 Novozymes A/S Lipase variants, polynucleotides encoding same and the use thereof
EP3858145A1 (en) * 2016-12-23 2021-08-04 Arla Foods amba Production of novel beta-lactoglobulin preparations and related methods, uses, and food products
WO2018202846A1 (en) 2017-05-05 2018-11-08 Novozymes A/S Compositions comprising lipase and sulfite
WO2019002356A1 (en) 2017-06-30 2019-01-03 Novozymes A/S ENZYMATIC SUSPENSION COMPOSITION
WO2019110462A1 (en) 2017-12-04 2019-06-13 Novozymes A/S Lipase variants and polynucleotides encoding same
WO2024032881A1 (en) 2022-08-10 2024-02-15 Arla Foods Amba Crystallisation of a protein capable of crystallizing under salting-in conditions using multiple protein feeds

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3642582A (en) * 1969-07-14 1972-02-15 Standard Brands Inc Purification of alpha amylase
US4659667A (en) * 1985-02-26 1987-04-21 Miles Laboratories, Inc. Process to recover crystalline enzymes and crystalline enzymes produced thereby
DK122686D0 (da) 1986-03-17 1986-03-17 Novo Industri As Fremstilling af proteiner
ATE125865T1 (de) 1987-08-28 1995-08-15 Novo Nordisk As Rekombinante humicola-lipase und verfahren zur herstellung von rekombinanten humicola-lipasen.

Also Published As

Publication number Publication date
EP0691982B1 (en) 1998-09-16
JPH08508168A (ja) 1996-09-03
US5719048A (en) 1998-02-17
JP3542601B2 (ja) 2004-07-14
ES2124400T3 (es) 1999-02-01
FI954648A0 (fi) 1995-09-29
DE69413389T2 (de) 1999-04-29
CN1039244C (zh) 1998-07-22
EP0691982A1 (en) 1996-01-17
WO1994022903A1 (en) 1994-10-13
ATE171189T1 (de) 1998-10-15
DK39693D0 (da) 1993-04-02
AU6424294A (en) 1994-10-24
FI954648A (fi) 1995-09-29
DK0691982T3 (da) 1999-06-14
CN1120340A (zh) 1996-04-10
KR960701082A (ko) 1996-02-24
EP0691982B2 (en) 2008-03-12
DE69413389D1 (de) 1998-10-22

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Legal Events

Date Code Title Description
EG Technical examination (opinion): publication of technical examination (opinion)
FC Decision: refusal