DE69413389D1 - Trennung von proteinen - Google Patents

Trennung von proteinen

Info

Publication number
DE69413389D1
DE69413389D1 DE69413389T DE69413389T DE69413389D1 DE 69413389 D1 DE69413389 D1 DE 69413389D1 DE 69413389 T DE69413389 T DE 69413389T DE 69413389 T DE69413389 T DE 69413389T DE 69413389 D1 DE69413389 D1 DE 69413389D1
Authority
DE
Germany
Prior art keywords
pct
proteins
enzyme
sec
separation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69413389T
Other languages
English (en)
Other versions
DE69413389T2 (de
Inventor
Birgitte Mahler Nilsson
Mads Aage Laustsen
Christine Pahle
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novozymes AS
Original Assignee
Novo Nordisk AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8093052&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69413389(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novo Nordisk AS filed Critical Novo Nordisk AS
Publication of DE69413389D1 publication Critical patent/DE69413389D1/de
Application granted granted Critical
Publication of DE69413389T2 publication Critical patent/DE69413389T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/02General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length in solution
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/16Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/18Carboxylic ester hydrolases (3.1.1)
    • C12N9/20Triglyceride splitting, e.g. by means of lipase
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14Extraction; Separation; Purification
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/814Enzyme separation or purification
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/814Enzyme separation or purification
    • Y10S435/816Enzyme separation or purification by solubility

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Peptides Or Proteins (AREA)
DE69413389T 1993-04-02 1994-03-29 Trennung von proteinen Expired - Lifetime DE69413389T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DK93396A DK39693D0 (da) 1993-04-02 1993-04-02 Enzym
PCT/DK1994/000132 WO1994022903A1 (en) 1993-04-02 1994-03-29 Separation of proteins

Publications (2)

Publication Number Publication Date
DE69413389D1 true DE69413389D1 (de) 1998-10-22
DE69413389T2 DE69413389T2 (de) 1999-04-29

Family

ID=8093052

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69413389T Expired - Lifetime DE69413389T2 (de) 1993-04-02 1994-03-29 Trennung von proteinen

Country Status (13)

Country Link
US (1) US5719048A (de)
EP (1) EP0691982B2 (de)
JP (1) JP3542601B2 (de)
KR (1) KR960701082A (de)
CN (1) CN1039244C (de)
AT (1) ATE171189T1 (de)
AU (1) AU6424294A (de)
BR (1) BR9406564A (de)
DE (1) DE69413389T2 (de)
DK (2) DK39693D0 (de)
ES (1) ES2124400T3 (de)
FI (1) FI954648A0 (de)
WO (1) WO1994022903A1 (de)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2021797A (en) * 1996-03-08 1997-09-22 Novo Nordisk A/S Crystallization of a protein with a sulphur salt
US6031082A (en) * 1996-03-14 2000-02-29 Novo Nordisk A/S Increased yields of a crystallized protein by using a solid adsorption material
US5914141A (en) * 1997-03-11 1999-06-22 Alfacel S.A. Easy peeling wiener casings via use of enzymes
US6140475A (en) * 1997-04-11 2000-10-31 Altus Biologics Inc. Controlled dissolution crosslinked protein crystals
US20010046493A1 (en) * 2000-02-24 2001-11-29 Alex Margolin Lipase-containing composition and methods of use thereof
US7142464B2 (en) * 2003-04-29 2006-11-28 Saifun Semiconductors Ltd. Apparatus and methods for multi-level sensing in a memory array
PL1729797T3 (pl) 2004-03-22 2009-02-27 Abbott Laboratories Gmbh Doustne kompozycje farmaceutyczne produktów zawierających lipazę, a zwłaszcza pankreatynę, zawierające środki powierzchniowo czynne
US7823635B2 (en) * 2004-08-23 2010-11-02 Halliburton Energy Services, Inc. Downhole oil and water separator and method
ATE474592T1 (de) * 2004-10-14 2010-08-15 Altus Pharmaceuticals Inc Zusammensetzungen enthaltend lipase, protease und amylase zur behandlung von pankreasinsuffizienz
CN101233229B (zh) 2005-07-29 2013-05-01 雅培实验室有限公司 制备消毒的胰酶粉末的方法
US11266607B2 (en) 2005-08-15 2022-03-08 AbbVie Pharmaceuticals GmbH Process for the manufacture and use of pancreatin micropellet cores
US9198871B2 (en) 2005-08-15 2015-12-01 Abbott Products Gmbh Delayed release pancreatin compositions
US20100196344A1 (en) * 2005-10-14 2010-08-05 Cystic Fibrosis Foundation Therapeutics, Inc. Compositions and methods for treating pancreatic insufficiency
US10072256B2 (en) 2006-05-22 2018-09-11 Abbott Products Gmbh Process for separating and determining the viral load in a pancreatin sample
RU2009128067A (ru) 2006-12-21 2011-01-27 Новозимс А/С (Dk) Варианты липаз для их применения в фармацевтике
WO2011000924A1 (en) 2009-07-03 2011-01-06 Abbott Products Gmbh Spray-dried amylase, pharmaceutical preparations comprising the same and use
WO2014053359A1 (en) * 2012-10-05 2014-04-10 Arcelik Anonim Sirketi Refrigerator comprising water dispenser
WO2015181118A1 (en) 2014-05-27 2015-12-03 Novozymes A/S Methods for producing lipases
EP3149178B1 (de) 2014-05-27 2020-07-15 Novozymes A/S Lipasevarianten und polynukleotide zur codierung davon
CN107002054A (zh) 2014-12-05 2017-08-01 诺维信公司 脂肪酶变体以及编码它们的多核苷酸
US10920203B2 (en) 2015-07-01 2021-02-16 Novozymes A/S Methods of reducing odor
US10822598B2 (en) 2015-07-06 2020-11-03 Novozymes A/S Lipase variants and polynucleotides encoding same
EP3384019B1 (de) 2015-12-01 2020-06-24 Novozymes A/S Verfahren zur herstellung von lipasen
WO2018015295A1 (en) 2016-07-18 2018-01-25 Novozymes A/S Lipase variants, polynucleotides encoding same and the use thereof
JP7222891B2 (ja) * 2016-12-23 2023-02-15 アーラ フーズ エエムビエ 新規のベータ-ラクトグロブリン調製物の製造ならびに関連する方法、使用および食品
CN110651038A (zh) 2017-05-05 2020-01-03 诺维信公司 包含脂肪酶和亚硫酸盐的组合物
CN111108183A (zh) 2017-06-30 2020-05-05 诺维信公司 酶浆液组合物
EP3720954A1 (de) 2017-12-04 2020-10-14 Novozymes A/S Lipasevarianten und polynukleotide zur codierung davon
WO2024032881A1 (en) 2022-08-10 2024-02-15 Arla Foods Amba Crystallisation of a protein capable of crystallizing under salting-in conditions using multiple protein feeds

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3642582A (en) * 1969-07-14 1972-02-15 Standard Brands Inc Purification of alpha amylase
US4659667A (en) * 1985-02-26 1987-04-21 Miles Laboratories, Inc. Process to recover crystalline enzymes and crystalline enzymes produced thereby
DK122686D0 (da) 1986-03-17 1986-03-17 Novo Industri As Fremstilling af proteiner
ATE125865T1 (de) 1987-08-28 1995-08-15 Novo Nordisk As Rekombinante humicola-lipase und verfahren zur herstellung von rekombinanten humicola-lipasen.

Also Published As

Publication number Publication date
CN1120340A (zh) 1996-04-10
EP0691982B1 (de) 1998-09-16
FI954648A (fi) 1995-09-29
JPH08508168A (ja) 1996-09-03
AU6424294A (en) 1994-10-24
EP0691982A1 (de) 1996-01-17
DK39693D0 (da) 1993-04-02
JP3542601B2 (ja) 2004-07-14
ES2124400T3 (es) 1999-02-01
WO1994022903A1 (en) 1994-10-13
US5719048A (en) 1998-02-17
CN1039244C (zh) 1998-07-22
FI954648A0 (fi) 1995-09-29
DK0691982T3 (da) 1999-06-14
DE69413389T2 (de) 1999-04-29
EP0691982B2 (de) 2008-03-12
ATE171189T1 (de) 1998-10-15
KR960701082A (ko) 1996-02-24
BR9406564A (pt) 1999-08-31

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Legal Events

Date Code Title Description
8363 Opposition against the patent
8327 Change in the person/name/address of the patent owner

Owner name: NOVOZYMES A/S, BAGSVAERD, DK

8366 Restricted maintained after opposition proceedings